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Sinalização Citoesquelética

Sinalização Citoesquelética

Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.

Foram encontrados 1382 produtos de "Sinalização Citoesquelética"

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  • SNIPER(ABL)-047


    <p>SNIPER(ABL)-047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels,</p>
    Fórmula:C67H82F3N11O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1274.5
  • 2119738-71-3

    CAS:
    <p>Compound 2119738-71-3 interacts with the FAK receptor.</p>
    Fórmula:C25H29ClFN7O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:513.99
  • SNIPER(ABL)-050


    <p>SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.</p>
    Fórmula:C68H84N12O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1213.47
  • Myelin Basic Protein

    CAS:
    <p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>
    Fórmula:C60H103N21O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1390.59
  • TC113


    <p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>
    Fórmula:C37H50F2N12O13
    Cor e Forma:Solid
    Peso molecular:908.86
  • hAChE-IN-2


    <p>hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-</p>
    Fórmula:C22H23FN4O2
    Cor e Forma:Solid
    Peso molecular:394.44
  • KT D606

    CAS:
    <p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>
    Fórmula:C59H50N6O10
    Cor e Forma:Solid
    Peso molecular:1003.06
  • Fuzapladib

    CAS:
    <p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>
    Fórmula:C15H20F3N3O3S
    Pureza:99.87%
    Cor e Forma:Soild
    Peso molecular:379.4
  • K34c hydrochloride

    CAS:
    <p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>
    Fórmula:C26H30ClN3O4
    Pureza:99.76% - 99.89%
    Cor e Forma:Soild
    Peso molecular:483.99
  • FDA-Approved Kinase Inhibitor Library


    <p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>
    Cor e Forma:Liquid
  • Protein kinase C α peptide TFA

    CAS:
    <p>Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.</p>
    Fórmula:C68H115F3N24O26S
    Cor e Forma:Solid
    Peso molecular:1773.85
  • Microtubule stabilizing agent-1


    <p>Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [</p>
    Fórmula:C45H55NO13
    Cor e Forma:Solid
    Peso molecular:817.92
  • T-808

    CAS:
    <p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>
    Fórmula:C17H19FN4
    Cor e Forma:Solid
    Peso molecular:298.36
  • αVβ8-IN-1

    CAS:
    <p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>
    Fórmula:C25H32ClN5O4
    Cor e Forma:Solid
    Peso molecular:502.01
  • ARM165


    <p>ARM165 is a heterobifunctional molecule that degrades the protein PIK3CG and inhibits the PI3Kγ-Akt signaling pathway, thereby exerting anti-leukemic effects. It is capable of suppressing the proliferation of AML cells, with an IC50 of less than 1 μM.</p>
    Fórmula:C44H51N7O8S
    Peso molecular:837.35198
  • BMP agonist 1


    <p>BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.</p>
    Fórmula:C21H16N2O6
    Cor e Forma:Solid
    Peso molecular:392.36
  • PROTAC HSP90 degrader BP3

    CAS:
    <p>PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.</p>
    Fórmula:C32H29ClN8O5
    Cor e Forma:Solid
    Peso molecular:641.08
  • KGP591


    <p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>
    Fórmula:C24H21NO5
    Cor e Forma:Solid
    Peso molecular:403.43
  • Microtubule-associated protein tau (26-44)


    <p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>
    Fórmula:C83H127N25O34S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2051.11
  • PDI-IN-4


    <p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>
    Fórmula:C17H12F3NO2
    Cor e Forma:Solid
    Peso molecular:319.278
  • FRATide

    CAS:
    <p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>
    Fórmula:C55H102N2O2
    Cor e Forma:Solid
    Peso molecular:823.433
  • Cepeginterferon alfa-2b

    CAS:
    <p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>
    Cor e Forma:Liquid
  • INY-03-041


    <p>INY-03-041, a PROTAC pan-AKT degrader, targets AKT1/2/3 with IC50s: 2.0/6.8/3.5 nM; GDC-0068 + Lenalidomide fusion.</p>
    Fórmula:C44H56ClN7O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:798.41
  • Hypoglycemic agent 3


    <p>Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.</p>
    Fórmula:C32H51NO5
    Cor e Forma:Solid
    Peso molecular:529.751
  • Lamifiban trifluoroacetate

    CAS:
    <p>Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).</p>
    Fórmula:C26H29F3N4O8
    Cor e Forma:Solid
    Peso molecular:582.533
  • Ceratamine A

    CAS:
    <p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>
    Fórmula:C17H16Br2N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:468.14
  • Fasudil

    CAS:
    <p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>
    Fórmula:C14H17N3O2S
    Pureza:99.79% - 99.84%
    Cor e Forma:Solid
    Peso molecular:291.37
  • Besufetamig

    CAS:
    <p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>
    Cor e Forma:Liquid
  • Mumefural

    CAS:
    <p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>
    Fórmula:C12H12O9
    Cor e Forma:Solid
    Peso molecular:300.22
  • Chemerin-9 (149-157)

    CAS:
    <p>Chemerin-9, a nonapeptide C-terminal fragment of chemerin, retains full protein's activity as a ChemR23 agonist.</p>
    Fórmula:C54H66N10O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1063.16
  • trans-Dehydrocurvularin

    CAS:
    <p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>
    Fórmula:C16H18O5
    Cor e Forma:Solid
    Peso molecular:290.315
  • Tubulin polymerization-IN-46


    <p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>
    Fórmula:C22H25NO6
    Cor e Forma:Solid
    Peso molecular:399.44
  • Crosstide

    CAS:
    <p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>
    Fórmula:C48H77N17O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1164.23
  • PROTAC BCR-ABL Degrader-1


    <p>PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and</p>
    Fórmula:C43H40N10O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:792.84
  • Dentonin TFA


    <p>Dentonin TFA (AC-100 TFA) is a short peptide fragment derived from MEPE. It enhances osteogenesis by promoting the adhesion of osteoprogenitor cells and supports the survival of immature adherent cells. Dentonin TFA does not have a significant effect on mature osteoblasts and can be utilized in studies of phosphate homeostasis and bone metabolism.</p>
    Fórmula:C109H161F3N30O44
    Peso molecular:2651.1235
  • Dihydrocephalomannine

    CAS:
    <p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>
    Fórmula:C45H55NO14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:833.928
  • ALB-109564 dihydrochloride

    CAS:
    <p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>
    Fórmula:C47H62Cl2N4O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:929.99
  • para-amino-Blebbistatin

    CAS:
    <p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>
    Fórmula:C18H17N3O2
    Cor e Forma:Solid
    Peso molecular:307.353
  • Coronaridine

    CAS:
    <p>Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.</p>
    Fórmula:C21H26N2O2
    Cor e Forma:Solid
    Peso molecular:338.451
  • tau/Aβ40 aggregation-IN-1


    <p>Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1].</p>
    Fórmula:C23H28N2O2S
    Cor e Forma:Solid
    Peso molecular:396.55
  • TTBK1-IN-2

    CAS:
    <p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>
    Fórmula:C18H13ClN4O
    Pureza:99.83%
    Cor e Forma:Soild
    Peso molecular:336.77
  • MK2-IN-5

    CAS:
    <p>MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and</p>
    Fórmula:C61H113N21O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1396.68
  • Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Tubulin inhibitor 45


    <p>Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.</p>
    Fórmula:C19H18N2O2S
    Peso molecular:338.1089
  • SNIPER(ABL)-013


    <p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>
    Fórmula:C42H52F3N7O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:839.9
  • Akt/SKG Substrate Peptide

    CAS:
    <p>substrate for Akt/PKB</p>
    Fórmula:C36H59N13O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:817.94
  • H2-Gamendazole

    CAS:
    <p>H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins &amp; EF1α, regulates Hsp90.</p>
    Fórmula:C18H13Cl2F3N2O2
    Pureza:97.36%
    Cor e Forma:Solid
    Peso molecular:417.21
  • 187-1, N-WASP inhibitor

    CAS:
    <p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>
    Fórmula:C96H122N18O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1784.13
  • LDV-FITC TFA


    <p>LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.</p>
    Fórmula:C69H81N11O17S·xC2HF3O2
  • LDV FITC

    CAS:
    <p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>
    Fórmula:C69H81N11O17S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1368.53
  • PDK-IN-1

    CAS:
    <p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>
    Fórmula:C20H16BrN7O
    Cor e Forma:Solid
    Peso molecular:450.29
  • G-5555 hydrochloride (1648863-90-4 free base)


    <p>G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.</p>
    Fórmula:C25H26Cl2N6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:529.42
  • DSPE-PEG2000-iRGD


    <p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>
    Cor e Forma:Odour Solid
  • 4,4'-Di-O-methylellagic acid

    CAS:
    <p>4,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences. The catalog number is T125016 and the CAS number is 3374-77-4.</p>
    Fórmula:C16H10O8
    Cor e Forma:Solid
    Peso molecular:330.248
  • PKCiota-IN-2

    CAS:
    <p>PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).</p>
    Fórmula:C24H21N5O
    Pureza:98.86%
    Cor e Forma:Solid
    Peso molecular:395.46
  • Zolbetuximab MMAE


    <p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>
    Pureza:95% - 95%
    Cor e Forma:Liquid
    Peso molecular:150 kDa
  • Protein Kinase C (19-36)

    CAS:
    Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.
    Fórmula:C93H159N35O24
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2151.48
  • 20-O-Demethyl-AP3

    CAS:
    <p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>
    Fórmula:C31H41ClN2O9
    Cor e Forma:Solid
    Peso molecular:621.12
  • Chaetominine

    CAS:
    <p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>
    Fórmula:C22H18N4O4
    Cor e Forma:Solid
    Peso molecular:402.40
  • PROTAC tubulin-Degrader-1


    <p>PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.</p>
    Cor e Forma:Odour Solid
  • HA15-Biotin

    CAS:
    <p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>
    Fórmula:C37H45N7O5S3
    Cor e Forma:Solid
    Peso molecular:763.99
  • Dynamin inhibitory peptide TFA


    <p>Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.</p>
    Fórmula:C49H81F3N18O16
    Cor e Forma:Solid
    Peso molecular:1235.27
  • Cys-McMMAF

    CAS:
    <p>Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.</p>
    Fórmula:C52H83N7O13S
    Cor e Forma:Solid
    Peso molecular:1046.32
  • Mps1-IN-6


    <p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>
    Fórmula:C35H39N9O3
    Cor e Forma:Solid
    Peso molecular:633.74
  • Tabituximab barzuxetan

    CAS:
    <p>Tabituximab barzuxetan: Humanized antibody FZD-10-targeted, Yttrium-90 labeled, for synovial sarcoma research.</p>
    Cor e Forma:Solid
  • HSDVHK-NH2

    CAS:
    <p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>
    Fórmula:C30H48N12O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:720.78
  • Microtubule destabilizing agent-1

    CAS:
    <p>Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.</p>
    Fórmula:C22H26N4O4
    Cor e Forma:Solid
    Peso molecular:410.47
  • Integrin Binding Peptide

    CAS:
    <p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>
    Fórmula:C42H63N15O16S
    Cor e Forma:Solid
    Peso molecular:1066.12
  • Foxy-5

    CAS:
    <p>Foxy-5 is a wnt5a peptide mimetic</p>
    Fórmula:C26H42N6O12S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:694.77
  • Tubulin inhibitor 38


    <p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>
    Fórmula:C17H13ClN6OS
    Cor e Forma:Solid
    Peso molecular:384.84
  • DSPE-PEG2000-cRGD


    <p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>
    Cor e Forma:Odour Solid
  • Combretastatin A-1 phosphate tetrasodium

    CAS:
    <p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>
    Fórmula:C18H18Na4O12P2
    Cor e Forma:Solid
    Peso molecular:580.24
  • 11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27
  • DSPE-PEG1000-iRGD


    <p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>
    Cor e Forma:Odour Solid
  • Phallacidin

    CAS:
    <p>Phallacidin, a phallotoxin family member, targets and binds to F-actin in mushroom toxins.</p>
    Fórmula:C37H50N8O13S
    Cor e Forma:Solid
    Peso molecular:846.91
  • Bimosiamose

    CAS:
    <p>Bimosiamose has anti-inflammatory effects[1].</p>
    Fórmula:C46H54O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:862.91
  • GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Fórmula:C22H37N9O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:587.58
  • MAL3-101

    CAS:
    <p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>
    Fórmula:C54H66N4O10
    Cor e Forma:Solid
    Peso molecular:931.12
  • Tubulin polymerization-IN-78


    <p>Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.</p>
    Cor e Forma:Odour Solid
  • Tubulin inhibitor 36


    <p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>
    Fórmula:C16H13ClN6S
    Cor e Forma:Solid
    Peso molecular:356.83
  • Phomopsin A

    CAS:
    <p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>
    Fórmula:C36H45ClN6O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:789.23
  • JG-258

    CAS:
    <p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>
    Fórmula:C20H22ClN3OS3
    Cor e Forma:Solid
    Peso molecular:452.06
  • PKCδ Peptide Substrate

    CAS:
    <p>PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) and</p>
    Fórmula:C109H191N35O29S
    Cor e Forma:Solid
    Peso molecular:2487.97
  • Anhydrovinblastine sulfate


    Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.
    Fórmula:C46H60N4O16S2
    Peso molecular:988.34457
  • Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)

    CAS:
    <p>Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.</p>
    Fórmula:C22H35N9O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:569.57
  • Ifebemtinib FA


    <p>BI-853520 FA (Ifebemtinib FA) is an orally active inhibitor of adhesion patch kinase with anticancer and antiproliferative activity for ovarian and lung cancer.</p>
    Fórmula:C29H30F4N6O6
    Pureza:98.05% - 99.73%
    Cor e Forma:Solid
    Peso molecular:634.58
  • TAT-P110

    CAS:
    TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.
    Fórmula:C100H178N44O26
    Peso molecular:2412.76
  • Delcasertib acetate


    <p>Delcasertib acetate is a selective δ protein kinase C (δPKC) inhibitor for the study of acute myocardial infarction and pain.</p>
    Fórmula:C122H203N45O36S2
    Pureza:98.92%
    Cor e Forma:Solid
    Peso molecular:2940.33
  • hCA/Wnt/β-catenin-IN-1


    <p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>
    Cor e Forma:Odour Solid
  • PKCε inhibitor peptide,myristoylated


    <p>Myristoylated PKCε inhibitor peptide (Myr-PKCε-) is a cell-permeable inhibitor consisting of a peptide linked to myristic acid that specifically inhibits</p>
    Fórmula:C51H91N9O14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1054.32
  • HSP90-IN-23


    <p>HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.</p>
    Fórmula:C22H24N2O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:444.5
  • GSK 3008348 hydrochloride

    CAS:
    <p>GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.</p>
    Fórmula:C29H37N5O2xHCl
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:0
  • 6BrCaQ-C10-TPP


    <p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>
    Fórmula:C45H47Br2N2O3P
    Cor e Forma:Solid
    Peso molecular:854.65
  • KTC1101

    CAS:
    <p>KTC1101 is a pan-PI3K inhibitor with antiproliferative and anticancer activities, reducing phosphorylation of downstream AKT and mTOR.</p>
    Fórmula:C21H26F2N8O3
    Pureza:98.75%
    Cor e Forma:Soild
    Peso molecular:476.48
  • Gantofiban

    CAS:
    <p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>
    Fórmula:C21H29N5O6
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:447.48
  • DSPE-PEG5000-cRGD


    <p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>
    Cor e Forma:Odour Solid
  • AT7867 dihydrochloride

    CAS:
    <p>AT7867 dihydrochloride inhibits Akt1/2/3 and p70S6K/PKA, with IC50s: 32/17/47 nM &amp; 85/20 nM, respectively, and hampers tumor growth.</p>
    Fórmula:C20H22Cl3N3
    Cor e Forma:Solid
    Peso molecular:410.77
  • Debio 0932

    CAS:
    <p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>
    Fórmula:C22H30N6O2S
    Pureza:98.98%
    Cor e Forma:Solid
    Peso molecular:442.58
  • Ombrabulin hydrochloride

    CAS:
    <p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>
    Fórmula:C21H27ClN2O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:438.9
  • (±)-1,2-Diolein

    CAS:
    <p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>
    Fórmula:C39H72O5
    Cor e Forma:Solid
    Peso molecular:620.99