Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1381 produtos de "Sinalização Citoesquelética"
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Pamidronate disodium pentahydrate
CAS:<p>Pamidronate disodium pentahydrate strengthens bones and prevents osteoporosis.</p>Fórmula:C3H21NNa2O12P2Pureza:99.84%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:371.13AT7867
CAS:<p>AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.</p>Fórmula:C20H20ClN3Pureza:99.63%Cor e Forma:SolidPeso molecular:337.85AKT-IN-1
CAS:<p>AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).</p>Fórmula:C22H21N3OPureza:98.63%Cor e Forma:SolidPeso molecular:343.42roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Fórmula:C21H29N5O6Pureza:98%Cor e Forma:SolidPeso molecular:447.48GNF-2
CAS:<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Fórmula:C18H13F3N4O2Pureza:98.17% - ≥95%Cor e Forma:SolidPeso molecular:374.32PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Fórmula:C19H28ClNO3Pureza:99.54%Cor e Forma:SolidPeso molecular:353.88Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Cor e Forma:White SolidPeso molecular:327.83Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Fórmula:C17H38BrNPureza:99.80%Cor e Forma:SolidPeso molecular:336.39Recilisib sodium
CAS:<p>Recilisib (ON 01210.Na) is a radioprotective agent altering cancer cell cycles and preventing radiation-induced apoptosis.</p>Fórmula:C16H13ClNaO4SCor e Forma:SolidPeso molecular:359.78Bisindolylmaleimide V
CAS:<p>Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.</p>Fórmula:C21H15N3O2Pureza:90%Cor e Forma:Red SolidPeso molecular:341.36Defactinib
CAS:<p>Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H21F3N8O3SPureza:98% - 99.71%Cor e Forma:SolidPeso molecular:510.49Tirbanibulin
CAS:<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Cor e Forma:SolidPeso molecular:431.53IM-12
CAS:<p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>Fórmula:C22H20FN3O2Pureza:99.42% - >99.99%Cor e Forma:SolidPeso molecular:377.41NSC45586
CAS:<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Fórmula:C20H18N6NaO3Pureza:99.31%Cor e Forma:SolidPeso molecular:413.4Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Fórmula:C31H43F6N9O12Pureza:95.28% - ≥95%Cor e Forma:SolidPeso molecular:847.72Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Cor e Forma:SolidPeso molecular:360.31Grp94 Inhibitor-1
CAS:<p>Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).</p>Fórmula:C22H28N2O2Pureza:97.02%Cor e Forma:SolidPeso molecular:352.47FRAX486 HCL(1232030-35-1 free base)
<p>FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.</p>Fórmula:C25H24Cl3FN6OPureza:98.85% - 99.82%Cor e Forma:SolidPeso molecular:549.86Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Cor e Forma:SolidPeso molecular:569.44Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.66
