Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1384 produtos de "Sinalização Citoesquelética"
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PU-H54
CAS:<p>PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.</p>Fórmula:C18H19N5SPureza:99.13%Cor e Forma:SolidPeso molecular:337.44Milnacipran ((1S-cis) hydrochloride)
CAS:<p>Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.</p>Fórmula:C15H23ClN2OPureza:99.81%Cor e Forma:SolidPeso molecular:282.81Smurf1-IN-A01
CAS:<p>Smurf1-IN-A01 is a potent Smurf1 inhibitor enhancing BMP-2, with a Kd of 3.664 nM, preventing Smad1/5 degradation.</p>Fórmula:C22H20ClF3N4O3SPureza:99.46%Cor e Forma:SolidPeso molecular:512.93TNIK-IN-2
CAS:<p>TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.</p>Fórmula:C22H19N3O3Pureza:99.54%Cor e Forma:SolidPeso molecular:373.42-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Fórmula:C11H11F3N2O4Pureza:99.45% - 99.82%Cor e Forma:SolidPeso molecular:292.21Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Cor e Forma:SolidPeso molecular:322.31HSP27 inhibitor J2
CAS:<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Fórmula:C13H12O4SPureza:99.51%Cor e Forma:SolidPeso molecular:264.3NRX-252262
CAS:<p>NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)</p>Fórmula:C23H17Cl2F3N2O4SPureza:98.94% - 99.87%Cor e Forma:SolidPeso molecular:545.36KBU2046
CAS:<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Fórmula:C15H11FO2Pureza:99.89%Cor e Forma:SolidPeso molecular:242.24Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Fórmula:C12H15N3O3SPureza:97.29%Cor e Forma:White To Off-White PowderPeso molecular:281.33Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Fórmula:C24H31N3O3Pureza:98.05% - 99.66%Cor e Forma:SolidPeso molecular:409.52TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Cor e Forma:SolidPeso molecular:474.33Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Cor e Forma:Off-White PowderPeso molecular:466.53CK-869
CAS:<p>CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.</p>Fórmula:C17H16BrNO3SPureza:99.85%Cor e Forma:SolidPeso molecular:394.28Aficamten
CAS:<p>Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.</p>Fórmula:C18H19N5O2Pureza:99.19% - 99.57%Cor e Forma:SolidPeso molecular:337.38Fingolimod
CAS:<p>Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).</p>Fórmula:C19H33NO2Pureza:99.53% - 99.6%Cor e Forma:SolidPeso molecular:307.47Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Cor e Forma:SolidPeso molecular:717.69Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Cor e Forma:SolidPeso molecular:384.27CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Fórmula:C26H32BrN5O6Pureza:98.05% - 99.83%Cor e Forma:SolidPeso molecular:590.47AZ13705339 hemihydrate
<p>AZ13705339 hemihydrate: potent PAK1 inhibitor (IC50: 0.33 nM), also binds PAK1/2 (Kd: 0.28/0.32 nM), for cancer research.</p>Fórmula:C33H36FN7O3SH2OCor e Forma:SolidPeso molecular:638.77
