Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1381 produtos de "Sinalização Citoesquelética"
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GNF-5
CAS:<p>GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.</p>Fórmula:C20H17F3N4O3Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:418.37Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Cor e Forma:SolidPeso molecular:603.67[Ala113]-MBP (104-118) acetate
<p>[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.</p>Fórmula:C69H108N20O21Pureza:97.72%Cor e Forma:SolidPeso molecular:1553.74MMAD
CAS:<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Fórmula:C41H66N6O6SPureza:99.25% - 99.91%Cor e Forma:SolidPeso molecular:771.06XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Cor e Forma:SolidPeso molecular:437.54TPPB
CAS:<p>TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).</p>Fórmula:C27H30F3N3O3Pureza:97.71% - 98.00%Cor e Forma:SolidPeso molecular:501.54Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Fórmula:C25H23N5O2S·CH4O3SPureza:98.79% - 99.02%Cor e Forma:SolidPeso molecular:553.65Flumatinib mesylate
CAS:<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Fórmula:C30H33F3N8O4SPureza:99.82%Cor e Forma:SolidPeso molecular:658.69Borussertib
CAS:<p>Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)</p>Fórmula:C36H32N6O3Pureza:99.00%Cor e Forma:SolidPeso molecular:596.68Ingenol
CAS:<p>Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.</p>Fórmula:C20H28O5Pureza:99.78% - 99.87%Cor e Forma:SolidPeso molecular:348.43BX517
CAS:<p>BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.</p>Fórmula:C15H14N4O2Pureza:99.26%Cor e Forma:SolidPeso molecular:282.3Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Cor e Forma:SolidPeso molecular:292.35Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Fórmula:C16H18N2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:302.39T807
CAS:T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).Fórmula:C16H10FN3Pureza:99.72%Cor e Forma:SolidPeso molecular:263.27PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Cor e Forma:SolidPeso molecular:501.5Curvulin
CAS:<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Fórmula:C12H14O5Pureza:98.65%Cor e Forma:SolidPeso molecular:238.24Mavacamten
CAS:<p>Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)</p>Fórmula:C15H19N3O2Pureza:99.53% - 99.98%Cor e Forma:SolidPeso molecular:273.33Hydroxy-Dynasore
CAS:<p>Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,</p>Fórmula:C18H14N2O5Pureza:97.60% - >99.99%Cor e Forma:SolidPeso molecular:338.31PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Fórmula:C24H21N5O2Pureza:99.33%Cor e Forma:SolidPeso molecular:411.46
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