Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1381 produtos de "Sinalização Citoesquelética"
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Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Fórmula:C13H14N2O4Pureza:99.61%Cor e Forma:SolidPeso molecular:262.26XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Fórmula:C25H21Cl2N3O8Cor e Forma:SolidPeso molecular:562.36Debio 0617B
CAS:<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Fórmula:C28H23ClF3N7O2Cor e Forma:SolidPeso molecular:581.98Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Fórmula:C17H11NO2Cor e Forma:SolidPeso molecular:261.27Antitumor agent-71
CAS:<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Fórmula:C26H31N5O4SCor e Forma:SolidPeso molecular:509.62BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Fórmula:C25H25ClN6O2SCor e Forma:SolidPeso molecular:509.02PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Fórmula:C20H21ClFN5O3Cor e Forma:SolidPeso molecular:433.86KIF18A-IN-4
CAS:KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.Fórmula:C22H27N3O3SCor e Forma:SolidPeso molecular:413.53K-80003
CAS:K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.Fórmula:C22H21FO2Pureza:99.45%Cor e Forma:SolidPeso molecular:336.4PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Fórmula:C23H19ClO2Pureza:98%Cor e Forma:SolidPeso molecular:362.85AKT-IN-2
CAS:<p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>Fórmula:C25H34F3N7OPureza:98%Cor e Forma:SolidPeso molecular:505.58GB1874
CAS:<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Fórmula:C24H27N3O2SCor e Forma:SolidPeso molecular:421.56AMP-PCP
CAS:<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Fórmula:C11H18N5O12P3Pureza:98%Cor e Forma:SolidPeso molecular:505.21Eg5 Inhibitor V, trans-24
CAS:<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Fórmula:C26H21N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:423.46BBO-10203
CAS:<p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>Fórmula:C34H30F2N6O3SPureza:98.62%Cor e Forma:SolidPeso molecular:640.7TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Fórmula:C17H20N6OPureza:98%Cor e Forma:SolidPeso molecular:324.38KP-23172
CAS:<p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>Fórmula:C10H4N6OPureza:98%Cor e Forma:SolidPeso molecular:224.18Tyrphostin AG 568
CAS:<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Fórmula:C13H9N5O2Pureza:98%Cor e Forma:SolidPeso molecular:267.24AS1938909
CAS:<p>AS1938909: SHIP2 inhibitor boosts Akt phosphorylation, glucose use, and uptake via GLUT1 in L6 myotubes.</p>Fórmula:C19H13Cl2F2NO2SPureza:98%Cor e Forma:SolidPeso molecular:428.28DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Fórmula:C18H14N2OCor e Forma:SolidPeso molecular:274.32
