Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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PP2A Cancerous-IN-1
CAS:<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Fórmula:C30H24N4O3Cor e Forma:SolidPeso molecular:488.54Dihydrocytochalasin B
CAS:<p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>Fórmula:C29H39NO5Pureza:98%Cor e Forma:SolidPeso molecular:481.62AG-205
CAS:<p>(rac)-AG-205 inhibits Pgrmc1, affects sterol gene INSIG1, and hinder NF-kB/BDNF/PI3K/AKT in neuronal hypoxic resistance.</p>Fórmula:C22H23ClN6OSCor e Forma:SolidPeso molecular:454.98O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Fórmula:C16H22FN5O3SCor e Forma:SolidPeso molecular:383.44ML-9 Free Base
CAS:<p>ML-9 suppresses MLCK, PKA, PKC (Ki: 4, 32, 54 μM), inhibits Akt kinase & STIM1, and induces autophagy.</p>Fórmula:C15H17ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:324.83CHPG
CAS:<p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>Fórmula:C8H8ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:201.61Litronesib Racemate
CAS:<p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>Fórmula:C23H37N5O4S2Cor e Forma:SolidPeso molecular:511.7TOK-8801
CAS:<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Fórmula:C17H21N3OSPureza:99.97%Cor e Forma:SolidPeso molecular:315.43Tubulin inhibitor 26
CAS:<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Fórmula:C17H19N3O3Cor e Forma:SolidPeso molecular:313.35Cardionogen 1
CAS:<p>Wnt signaling modulator</p>Fórmula:C13H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:274.34Creatine monohydrate
CAS:<p>Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.</p>Fórmula:C4H11N3O3Pureza:99.87%Cor e Forma:White SolidPeso molecular:149.15BIIB028
CAS:<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Fórmula:C19H21ClN5O5PCor e Forma:SolidPeso molecular:465.83Hsp90-Cdc37-IN-1
CAS:<p>Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.</p>Fórmula:C43H57FN2O6SPureza:98%Cor e Forma:SolidPeso molecular:748.99(S)-Dolaphenine hydrochloride
CAS:<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Fórmula:C11H13ClN2SPureza:98%Cor e Forma:SolidPeso molecular:240.75Microtubule inhibitor 7
CAS:<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Fórmula:C25H19FN2O5Cor e Forma:SolidPeso molecular:446.43Amphethinile
CAS:<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Fórmula:C15H11N3SPureza:98%Cor e Forma:SolidPeso molecular:265.33CH5138303
CAS:<p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>Fórmula:C19H18ClN5O2SPureza:98%Cor e Forma:SolidPeso molecular:415.9CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:98.38%Cor e Forma:SolidPeso molecular:235.24Microtubule inhibitor 3
CAS:<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Fórmula:C26H23FN4O3Cor e Forma:SolidPeso molecular:458.48PPY A
CAS:<p>PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cells</p>Fórmula:C22H20N4O2Pureza:98.77%Cor e Forma:SolidPeso molecular:372.42
