Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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β-Catenin modulator-4
CAS:<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H21ClN2O2SCor e Forma:SolidPeso molecular:400.92CNS-11
CAS:<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Fórmula:C25H21N3O2Cor e Forma:SolidPeso molecular:395.45MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Cor e Forma:SolidPeso molecular:1115.71Oxaline
CAS:<p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>Fórmula:C24H25N5O4Cor e Forma:SolidPeso molecular:447.49Tubulin polymerization-IN-52
CAS:<p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>Fórmula:C21H18F3N5O3Cor e Forma:SolidPeso molecular:445.39EG-011
CAS:<p>EG-011, a potent first-in-class WASP activator, enhances actin polymerization, showing selective anti-tumor effects in lymphomas.</p>Fórmula:C28H26N4O4Cor e Forma:SolidPeso molecular:482.53KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Cor e Forma:SolidPeso molecular:356.41Valecobulin hydrochloride
CAS:<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Fórmula:C26H29ClN6O5SPureza:99.52%Cor e Forma:SolidPeso molecular:573.06Paluratide
CAS:<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Fórmula:C73H105F5N12O12Pureza:98.70%Cor e Forma:SolidPeso molecular:1437.68CCT251455
CAS:<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Fórmula:C26H26ClN7O2Pureza:99.1% - 99.1%Cor e Forma:SolidPeso molecular:503.98Demethylasterriquinone B1
CAS:<p>insulin receptor (IR) activator</p>Fórmula:C32H30N2O4Pureza:98%Cor e Forma:SolidPeso molecular:506.59ER degrader 7
CAS:<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Fórmula:C33H31F4N3O5SSeCor e Forma:SolidPeso molecular:736.63ASN90
CAS:<p>ASN90 is a specific, orally active inhibitor of the O-GlcNAcase (OGA) enzyme, demonstrating an IC50 of 10.2 nM.</p>Fórmula:C17H21N5O3SCor e Forma:SolidPeso molecular:375.45Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Fórmula:C26H25BrN4O3Pureza:98%Cor e Forma:SolidPeso molecular:521.41HSP90-IN-29
CAS:<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Fórmula:C19H20ClN3O4Cor e Forma:SolidPeso molecular:389.83Akt-I-1,2
CAS:<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Fórmula:C23H22ClN3Pureza:99.95%Cor e Forma:SolidPeso molecular:375.89PVZB1194
CAS:<p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>Fórmula:C13H9F4NO2SPureza:98%Cor e Forma:SolidPeso molecular:319.283,4',5-Trismethoxybenzophenone
CAS:<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Fórmula:C16H16O4Cor e Forma:SolidPeso molecular:272.3TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Fórmula:C27H25F3N4O4Pureza:99.39% - ≥98%Cor e Forma:SolidPeso molecular:526.51Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Fórmula:C22H37ClN2O5SPureza:98%Cor e Forma:SolidPeso molecular:477.06
