Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Fórmula:C39H65N5O8Pureza:97.00% - 99.88%Cor e Forma:SolidPeso molecular:731.96Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Cor e Forma:SolidPeso molecular:517.06Gap 26
CAS:<p>Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.</p>Fórmula:C70H107N19O19SPureza:98.26%Cor e Forma:SolidPeso molecular:1550.78Dasatinib N-oxide
CAS:<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Fórmula:C22H26ClN7O3SPureza:98.54% - 99.94%Cor e Forma:SolidPeso molecular:504PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Fórmula:C25H30F3N5O4Pureza:99.04%Cor e Forma:SolidPeso molecular:521.53XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Fórmula:C29H37N5O3Pureza:99.18%Cor e Forma:SolidPeso molecular:503.64H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Fórmula:C23H38N10O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:614.61PKC ζ pseudosubstrate acetate
<p>PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.</p>Fórmula:C78H132N30O18Pureza:98.78%Cor e Forma:SolidPeso molecular:1778.10ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Cor e Forma:SolidPeso molecular:533.59Fingolimod hydrochloride
CAS:<p>Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).</p>Fórmula:C19H34ClNO2Pureza:99.26% - 99.83%Cor e Forma:White SolidPeso molecular:343.93HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Cor e Forma:Pale Yellow Crystalline SolidPeso molecular:277.34Plinabulin
CAS:<p>Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).</p>Fórmula:C19H20N4O2Pureza:98.69% - >99.99%Cor e Forma:SolidPeso molecular:336.39Hypocrellin A
CAS:<p>Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.</p>Fórmula:C30H26O10Pureza:98% - 99.81%Cor e Forma:SolidPeso molecular:546.52TAT-Gap19 acetate
<p>TAT-Gap19 acetate, a Cx43 HC inhibitor, crosses blood-brain barrier, reduces liver fibrosis in mice, and spares Cx43 GJCs.</p>Fórmula:C119H212N46O26Pureza:99.74%Cor e Forma:SolidPeso molecular:2703.25Nilotinib monohydrochloride monohydrate
CAS:<p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>Fórmula:C28H22F3N7O·HCl·H2OPureza:99.93%Cor e Forma:SolidPeso molecular:583.99Soblidotin
CAS:<p>Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.</p>Fórmula:C39H67N5O6Pureza:99.89%Cor e Forma:SolidPeso molecular:701.98Adaphostin
CAS:<p>Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.</p>Fórmula:C24H27NO4Pureza:98.29%Cor e Forma:SolidPeso molecular:393.48Protein Kinase C 19-31 acetate
<p>PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.</p>Fórmula:C69H122N26O18Pureza:>99.99%Cor e Forma:SolidPeso molecular:1603.9Hypericin
CAS:<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Fórmula:C30H16O8Pureza:99.05% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
<p>Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Fórmula:C19H34N8O11Pureza:99.81%Cor e Forma:SolidPeso molecular:550.52Lifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Cor e Forma:SolidPeso molecular:615.48PF-562271
CAS:<p>PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).</p>Fórmula:C21H20F3N7O3SPureza:97.17% - >99.99%Cor e Forma:SolidPeso molecular:507.49Bisindolylmaleimide V
CAS:<p>Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.</p>Fórmula:C21H15N3O2Pureza:90%Cor e Forma:Red SolidPeso molecular:341.36Defactinib
CAS:<p>Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H21F3N8O3SPureza:98% - 99.71%Cor e Forma:SolidPeso molecular:510.49PF-AKT400
CAS:<p>PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.</p>Fórmula:C20H22F2N6OPureza:98.21%Cor e Forma:SolidPeso molecular:400.43Estramustine
CAS:<p>Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.</p>Fórmula:C23H31Cl2NO3Pureza:98.09%Cor e Forma:SolidPeso molecular:440.4ML346
CAS:<p>ML346 is a novel activator of Hsp70.</p>Fórmula:C14H12N2O4Pureza:97.32% - 99.36%Cor e Forma:SolidPeso molecular:272.26PD173955
CAS:<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Fórmula:C21H16Cl2N4OSPureza:98.52% - 98.99%Cor e Forma:SolidPeso molecular:443.35ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Fórmula:C10H12N6OPureza:99.69%Cor e Forma:SolidPeso molecular:232.24Ansamitocin P 3'
CAS:<p>Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.</p>Fórmula:C32H43ClN2O9Pureza:98.16% - 99.16%Cor e Forma:SolidPeso molecular:635.14Pamidronate disodium pentahydrate
CAS:<p>Pamidronate disodium pentahydrate strengthens bones and prevents osteoporosis.</p>Fórmula:C3H21NNa2O12P2Pureza:99.84%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:371.13roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Fórmula:C21H29N5O6Pureza:98%Cor e Forma:SolidPeso molecular:447.48AST 487
CAS:<p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>Fórmula:C26H30F3N7O2Pureza:98.17% - 99.56%Cor e Forma:SolidPeso molecular:529.56IM-12
CAS:<p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>Fórmula:C22H20FN3O2Pureza:99.42% - >99.99%Cor e Forma:SolidPeso molecular:377.41Dynamin inhibitory peptide, myristoylated acetate
<p>Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.</p>Fórmula:C63H111N19O16Pureza:99.42%Cor e Forma:SolidPeso molecular:1390.67Olverembatinib
CAS:<p>Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).</p>Fórmula:C29H27F3N6OPureza:98.53% - >99.99%Cor e Forma:SolidPeso molecular:532.56[Ala107]-MBP (104-118) acetate
<p>[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).</p>Fórmula:C59H108N20O21Pureza:99.23%Cor e Forma:SolidPeso molecular:1553.72VER49009
CAS:<p>VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).</p>Fórmula:C19H18ClN3O4Pureza:98.95% - >99.99%Cor e Forma:SolidPeso molecular:387.82Cyclo(RADfK)
CAS:<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Fórmula:C28H43N9O7Pureza:>99.99%Cor e Forma:SolidPeso molecular:617.7Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Fórmula:C21H46N·BrPureza:99.09%Cor e Forma:Solid SolidPeso molecular:392.5Y15
CAS:<p>Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity,</p>Fórmula:C6H14Cl4N4Pureza:98% - 99.32%Cor e Forma:Dark Brown CrystalsPeso molecular:284.01E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Cor e Forma:SolidPeso molecular:336.37N-Phenylbenzylamine
CAS:<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Fórmula:C13H13NPureza:98.75%Cor e Forma:Colorless To Pale Yellow Crystalline PowderPeso molecular:183.25Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Fórmula:C21H24ClN2NaO4SPureza:99.82%Cor e Forma:SolidPeso molecular:458.93Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Cor e Forma:SolidPeso molecular:831.96 (free base)KNK437
CAS:<p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>Fórmula:C13H11NO4Pureza:98.90%Cor e Forma:SolidPeso molecular:245.23TAS-301
CAS:<p>TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.</p>Fórmula:C23H19NO3Pureza:99.55%Cor e Forma:SolidPeso molecular:357.4GNF-7
CAS:<p>GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.</p>Fórmula:C28H24F3N7O2Pureza:97.05% - 99.7%Cor e Forma:SolidPeso molecular:547.53CK-636
CAS:<p>CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.</p>Fórmula:C16H16N2OSPureza:98.1% - 98.88%Cor e Forma:SolidPeso molecular:284.38Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Fórmula:C29H36O15Pureza:97.46% - 99.55%Cor e Forma:SolidPeso molecular:624.59
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