Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1381 produtos de "Sinalização Citoesquelética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Questiomycin A
CAS:<p>Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.</p>Fórmula:C12H8N2O2Pureza:98.13% - 98.7%Cor e Forma:SolidPeso molecular:212.2Valecobulin
CAS:<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Fórmula:C26H28N6O5SPureza:98%Cor e Forma:SolidPeso molecular:536.6Neurodazine
CAS:<p>Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.</p>Fórmula:C27H21ClN2O3Pureza:98.01%Cor e Forma:SolidPeso molecular:456.92RO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Fórmula:C24H19Cl3N2O4Pureza:98.26%Cor e Forma:SolidPeso molecular:505.78Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C27H36N6O3Pureza:99.53%Cor e Forma:SolidPeso molecular:492.61Ruboxistaurin hydrochloride
CAS:<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Fórmula:C28H28N4O3·HClPureza:98.44% - 99.22%Cor e Forma:SolidPeso molecular:505.01Bosutinib hydrate
CAS:<p>Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.</p>Fórmula:C26H31Cl2N5O4Pureza:99.87%Cor e Forma:SolidPeso molecular:548.46Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Pureza:95% - 97.51% (SEC-HPLC)Cor e Forma:LiquidEtaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.3 (kDa)FAK activator 1
CAS:<p>ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.</p>Fórmula:C23H26F3N3O3Pureza:99.19%Cor e Forma:SoildPeso molecular:449.47Vevorisertib trihydrochloride
CAS:<p>Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.</p>Fórmula:C35H41Cl3N8OPureza:98.28%Cor e Forma:SolidPeso molecular:696.12H-Ile-Lys-Val-Ala-Val-OH
CAS:<p>H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite growth.</p>Fórmula:C25H48N6O6Pureza:99.92%Cor e Forma:SolidPeso molecular:528.69Alvespimycin
CAS:<p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>Fórmula:C32H48N4O8Pureza:99.88%Cor e Forma:SolidPeso molecular:616.75Arg-Gly-Asp-Ser
CAS:<p>Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.</p>Fórmula:C15H27N7O8Pureza:98.29%Cor e Forma:SolidPeso molecular:433.42NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Fórmula:C21H16N2O4Pureza:98.35%Cor e Forma:SolidPeso molecular:360.36Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Cor e Forma:SolidPeso molecular:480.6Enlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Cor e Forma:LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Cor e Forma:LiquidOdronextamab
CAS:<p>Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].</p>Cor e Forma:LiquidPosdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Cor e Forma:Liquid4-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Fórmula:C43H56N6O7Cor e Forma:SolidPeso molecular:768.94Linvoseltamab
CAS:<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Cor e Forma:LiquidWZU-13
CAS:<p>WZU-13 is an inhibitor of carboxylesterase (CES). At a concentration of 100 μM, WZU-13 suppresses 77% of CES activity.</p>Fórmula:C22H16N2OCor e Forma:SolidPeso molecular:324.38Gresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Cor e Forma:LiquidVibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Cor e Forma:LiquidOsemitamab
CAS:<p>Osemitamab (TST001) is a humanised monoclonal antibody targeting claudin-18.2, gastric/gastric-oesophageal junction adenocarcinoma, PDAC, and lung cancer.</p>Pureza:95%Cor e Forma:LiquidMeclofenamate sodium hydrate
CAS:<p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>Fórmula:C14H12Cl2NNaO3Cor e Forma:SolidPeso molecular:336.15Ubamatamab
CAS:<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Cor e Forma:LiquidVatelizumab
CAS:<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Pureza:95%Cor e Forma:LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Pureza:99%Cor e Forma:Odour LiquidNivatrotamab
<p>Nivatrotamab: Humanized anti-GD2/CD3 bispecific antibody for neuroblastoma research.</p>Cor e Forma:Odour LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Pureza:98%Cor e Forma:Odour LiquidSemorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Pureza:95% - 95%Cor e Forma:LiquidLixudebart
CAS:<p>Lixudebart is a humanised monoclonal antibody targeting CLDN1 (Claudin-1), which can be used to reverse organ fibrosis and reduce initial ALT/AST levels.</p>Pureza:95%Cor e Forma:LiquidPavurutamab
CAS:<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Cor e Forma:LiquidObrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Cor e Forma:LiquidTepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Cor e Forma:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Cor e Forma:LiquidVonsetamig
CAS:<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Cor e Forma:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Pureza:95%Cor e Forma:Odour LiquidRaludotatug
CAS:<p>Raludotatug is a humanized antibody targeting cadherin-6 (CDH6). As part of the ADC Raludotatug deruxtecan, it shows promise in researching platinum-sensitive ovarian cancer.</p>Pureza:95% - 95%Cor e Forma:LiquidFlotetuzumab
CAS:<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Cor e Forma:LiquidGosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Pureza:95% - 95%Cor e Forma:LiquidST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43Pasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Cor e Forma:LiquidPlamotamab
CAS:<p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>Cor e Forma:LiquidVepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Cor e Forma:LiquidPinatuzumab
CAS:<p>Pinatuzumab is a humanised monoclonal antibody targeting CD22, B-cell malignancies non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL).</p>Pureza:95%Cor e Forma:LiquidVoxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Cor e Forma:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Cor e Forma:Liquid
