Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Pureza:95.42%Cor e Forma:SoildBOS-172722
CAS:<p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>Fórmula:C24H30N8OPureza:99.37%Cor e Forma:SolidPeso molecular:446.55Bosutinib
CAS:<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Vedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Pureza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Cor e Forma:LiquidPeso molecular:146.80 kDaIPI-493
CAS:<p>IPI-493 is a bioactive chemical.</p>Fórmula:C28H39N3O8Pureza:>99.99%Cor e Forma:SolidPeso molecular:545.62Akt3 degrader 1
CAS:<p>Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.</p>Fórmula:C53H72N8O4Pureza:98.12% - 99.02%Cor e Forma:SolidPeso molecular:885.19BNC105
CAS:<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Fórmula:C20H20O7Pureza:96.57%Cor e Forma:SolidPeso molecular:372.37N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Fórmula:C28H29N7OPureza:98.60%Cor e Forma:Off-White To Pale-Yellow SolidPeso molecular:479.582,3-Butanedione 2-Monoxime
CAS:<p>2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.</p>Fórmula:C4H7NO2Pureza:98.62%Cor e Forma:Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:101.1Recilisib
CAS:<p>Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.</p>Fórmula:C16H13ClO4SPureza:98.85% - 98.96%Cor e Forma:SolidPeso molecular:336.79Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidVerubulin hydrochloride
CAS:<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Fórmula:C17H18ClN3OPureza:98.29% - 99.77%Cor e Forma:SolidPeso molecular:315.8RWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Fórmula:C18H17F3N4O2SPureza:99.09%Cor e Forma:SolidPeso molecular:410.41Danicamtiv
CAS:<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Fórmula:C16H20F3N5O4SPureza:99.38%Cor e Forma:SolidPeso molecular:435.42Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Cor e Forma:LiquidPeso molecular:145.79 kDaFluocinolone (Acetonide)
CAS:<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Fórmula:C24H30F2O6Pureza:99.29% - 99.82%Cor e Forma:Crystals From Acetone & Hexane SolidPeso molecular:452.49ADH-1 trifluoroacetate
CAS:<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Fórmula:C24H35F3N8O8S2Pureza:90.08% - 99.17%Cor e Forma:SolidPeso molecular:684.71Zagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Pureza:95% - > 95%Cor e Forma:LiquidPeso molecular:145.3 kDaAbciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:95.18 kDaImatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:589.71Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01Fluorofenidone
CAS:<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Fórmula:C12H10FNOPureza:99.85%Cor e Forma:SolidPeso molecular:203.21ATN-161 acetate
CAS:<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Fórmula:C25H39N9O10SPureza:98.27%Cor e Forma:SoildPeso molecular:657.7CMPD101
CAS:<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Fórmula:C24H21F3N6OPureza:99.01% - 99.04%Cor e Forma:SolidPeso molecular:466.46IMAB027
CAS:<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Pureza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Cor e Forma:LiquidMosunetuzumab
CAS:<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Pureza:SDS-PAGE:94.4%;SEC-HPLC:96.1%Cor e Forma:LiquidPeso molecular:146.27 kDaAS1949490
CAS:<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Fórmula:C20H18ClNO2SPureza:99.94%Cor e Forma:SolidPeso molecular:371.88Veltuzumab
CAS:<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Cor e Forma:LiquidOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Pureza:>95%Cor e Forma:LiquidMeclofenamic acid sodium
CAS:<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Fórmula:C14H10Cl2NNaO2Pureza:98% - 98.96%Cor e Forma:SolidPeso molecular:318.14Tubulin inhibitor 6
CAS:<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Fórmula:C20H14ClNO2SPureza:99.05%Cor e Forma:SolidPeso molecular:367.85ALK inhibitor 2
CAS:<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Fórmula:C23H28ClN7O3SPureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:518.03Vantictumab
CAS:<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Pureza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidDonanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Pureza:95%Cor e Forma:LiquidPamidronate Disodium
CAS:<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Fórmula:C3H9NNa2O7P2Pureza:99.86% - 99.93%Cor e Forma:White CrystalsPeso molecular:279.03Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Fórmula:C21H29N5O6Pureza:99.57%Cor e Forma:SolidPeso molecular:447.48GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Fórmula:C22H37N9O10Pureza:98%Cor e Forma:SolidPeso molecular:587.58Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Fórmula:C32H55N9O10Pureza:98%Cor e Forma:SolidPeso molecular:725.83DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Cor e Forma:Odour SolidPDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Fórmula:C25H17N3O2SPureza:99.93%Cor e Forma:SoildPeso molecular:423.49hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Cor e Forma:Odour SolidTubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Fórmula:C22H25NO6Cor e Forma:SolidPeso molecular:399.44DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Cor e Forma:Odour SolidSNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Fórmula:C42H52F3N7O8Pureza:98%Cor e Forma:SolidPeso molecular:839.9Epothilone F
CAS:<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Fórmula:C27H41NO7SCor e Forma:SolidPeso molecular:523.68Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Pureza:95% - 95%Cor e Forma:LiquidPeso molecular:150 kDahAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Fórmula:C22H24N4OCor e Forma:SolidPeso molecular:360.45Foxy-5
CAS:<p>Foxy-5 is a wnt5a peptide mimetic</p>Fórmula:C26H42N6O12S2Pureza:98%Cor e Forma:SolidPeso molecular:694.776BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Fórmula:C45H47Br2N2O3PCor e Forma:SolidPeso molecular:854.65trans-Dehydrocurvularin
CAS:<p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>Fórmula:C16H18O5Cor e Forma:SolidPeso molecular:290.315
