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Sinalização Citoesquelética

Sinalização Citoesquelética

Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.

Foram encontrados 1382 produtos de "Sinalização Citoesquelética"

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  • Tubulin inhibitor 6

    CAS:
    <p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>
    Fórmula:C20H14ClNO2S
    Pureza:99.05%
    Cor e Forma:Solid
    Peso molecular:367.85
  • ALK inhibitor 2

    CAS:
    <p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>
    Fórmula:C23H28ClN7O3S
    Pureza:99.77% - >99.99%
    Cor e Forma:Solid
    Peso molecular:518.03
  • Vantictumab

    CAS:
    <p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>
    Pureza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)
    Cor e Forma:Liquid
  • Donanemab

    CAS:
    <p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Pamidronate Disodium

    CAS:
    <p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>
    Fórmula:C3H9NNa2O7P2
    Pureza:99.86% - 99.93%
    Cor e Forma:White Crystals
    Peso molecular:279.03
  • Gantofiban

    CAS:
    <p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>
    Fórmula:C21H29N5O6
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:447.48
  • GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Fórmula:C22H37N9O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:587.58
  • Larazotide

    CAS:
    <p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>
    Fórmula:C32H55N9O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:725.83
  • DSPE-PEG2000-cRGD


    <p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>
    Cor e Forma:Odour Solid
  • PDS-0330

    CAS:
    <p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>
    Fórmula:C25H17N3O2S
    Pureza:99.93%
    Cor e Forma:Soild
    Peso molecular:423.49
  • hCA/Wnt/β-catenin-IN-1


    <p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>
    Cor e Forma:Odour Solid
  • Tubulin polymerization-IN-46


    <p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>
    Fórmula:C22H25NO6
    Cor e Forma:Solid
    Peso molecular:399.44
  • DSPE-PEG2000-iRGD


    <p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>
    Cor e Forma:Odour Solid
  • SNIPER(ABL)-013


    <p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>
    Fórmula:C42H52F3N7O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:839.9
  • Epothilone F

    CAS:
    <p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>
    Fórmula:C27H41NO7S
    Cor e Forma:Solid
    Peso molecular:523.68
  • Zolbetuximab MMAE


    <p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>
    Pureza:95% - 95%
    Cor e Forma:Liquid
    Peso molecular:150 kDa
  • hAChE-IN-1


    <p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>
    Fórmula:C22H24N4O
    Cor e Forma:Solid
    Peso molecular:360.45
  • Foxy-5

    CAS:
    <p>Foxy-5 is a wnt5a peptide mimetic</p>
    Fórmula:C26H42N6O12S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:694.77
  • 6BrCaQ-C10-TPP


    <p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>
    Fórmula:C45H47Br2N2O3P
    Cor e Forma:Solid
    Peso molecular:854.65
  • trans-Dehydrocurvularin

    CAS:
    <p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>
    Fórmula:C16H18O5
    Cor e Forma:Solid
    Peso molecular:290.315