Compostos Deuterados

Applications 2’,3’,5’-Tri-O-benzoyl Xanthine-13C5 is an intermediate used in the synthesis of Xanthosine-13C5 (X742102), which is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure.
References Magasanik, B, et al.: J. Bio. Chem., 206, 83 (1954);

Applications Pentadecanoic-15,15,15-d3 Acid (CAS# 352431-40-4) is a useful isotopically labeled research compound.

Applications Hexadecanoic-7,7,8,8-d4 Acid (CAS# 75736-49-1) is a useful isotopically labeled research compound.

Applications Hexadecanoic-13,13-d2 Acid (CAS# 62690-28-2) is a useful isotopically labeled research compound.

Applications 4-Chlorobiphenyl-2',3',4',5',6'-d5 (CAS# 51624-37-4) is a useful isotopically labeled research compound.

Applications A metabolite of Phosphatidylcholine, also inhibits the production of oxygen radicals during methane production.
References Liao, C., et al.: Eur. J. Pharmacol., 566, 103 (2007), Ghyczy, M., et al.: Cell. Physiol. Biochem., 21, 251 (2008),

Applications Dexamethasone Hemisuccinate-d4 is the isotope labelled analog of Dexamethasone Hemisuccinate (D298855); a derivative of Dexamethasone (D298800) which is a glucocorticoid used as an anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. Dexamethasone also inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)

Applications 3',4'-Dimethoxyacetophenone-d3 (methyl-d3) (CAS# 350818-54-1) is a useful isotopically labeled research compound.

Applications 2,2-Bis(4-hydroxyphenyl)propanol-d11 is labelled 2,2-Bis(4-hydroxyphenyl)propanol (B447360) which is a metabolite of bisphenol A (B519495). It works as an endocrine disruptor.
References Krishnan, A.V., et al.: Endocrinology, 132, 2279 (1993), Steinmetz, R., et al.: Trends Endocrinol. Metab., 9, 124 (1998); Kitamura, S., et al.: Toxicol. Sci., 84, 249 (2005)

Applications (±)-Carazolol-d7 is labelled (±)-Carazolol (C175810, HCl salt) which is a promising high-affinity beta-adrenergic receptor ligand for the noninvasive determination of beta receptor status using PET.
References Berridge, M.S., et al.: J. Nucl. Med., 35(10), 1665 (1994)

Applications Labelled Aldicarb Sulfoxide (A514665). Aldicarb Sulfoxide is an analog of Aldicarb (A514650) detected in agricultural products as pesticide residue.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985), Ashby, J., et al.: Mutat. Res., 257, 229 (1991), Kazius, J., et al.: J. Med. Chem., 48, 312 (2005), Benigni, R., et al.: Mutagenesis, 25, 335 (2010),

Applications 3-Pentanone-d10 (CAS# 54927-77-4) is a useful isotopically labeled research compound.