Compostos Deuterados

Applications D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 (CAS# 1426174-46-0) is a useful isotopically labeled research compound.

Applications 2-Hydroxyethyl Nortadalafil-d4 is the isotope labelled analog of 2-Hydroxyethyl Nortadalafil (H942245); a derivative of Tadalafil (T004500) which is a compound used for the treatment of erectile dysfunction. Also a phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)

Applications 4,4-Bis(4-aminophenylsulfonyl)-azobenzene-d16 is the isotope labelled analog of 4,4-Bis(4-aminophenylsulfonyl)-azobenzene. 4,4-Bis(4-aminophenylsulfonyl)-azobenzene is synthesized from dapsone (D193250), an antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

Applications Cyclohexanecarboxylic-1-d1 Acid (CAS# 933-37-9) is a useful isotopically labeled research compound.

Applications 3-Chlorotoluene-d7 (CAS# 1219804-88-2) is a useful isotopically labeled research compound.

Applications 4-(Phenyl-d5)-3-buten-2-one (cas# 56187-93-0) is a compound useful in organic synthesis.

Applications Monocrotaline-d4 is labelled Monocrotaline (M526000) which is a toxic pyrrolizidine alkaloid isolated from Crotalaria spp. It is used for inducing pulmonary diseases in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Newberne, P.M., et al.: Toxicol. Appl. Pharmacol., 18, 387 (1971), Bober, M.A., et al.: Toxicon, 27, 1059 (1989), Wilson, D.W., et al.: Crit. Rev. Toxicol., 22, 307 (1992),

Applications N,N-Dimethylaniline-d11 (CAS# 85785-00-8) is a useful isotopically labeled research compound.

Applications Isotope labelled N-Fmoc-glycine is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.
References Eulenberg, V., et al.: Trend. Biochem. Sci., 30, 325 (2005); Gundersen, R., et al.: Acta Anaesth. Scand., 49, 1108 (2005); Lockart, R. & Eagle, H.: Science, 129, 252 (1959); Sogabe, K., et al.: Kidn. Int., 50, 845 (1996)

Applications 4-Hydroxychlorpropham Sulfate-d7 Triethylamine is an intermediate used in the synthesis of 4-Hydroxychlorpropham-d7 Sulfate Sodium Salt (H825077), which is derived from Isopropanol-d7 (I822752), a deuterated alcohol used in the study of lignite liquefaction.
References Kuznetov, P.N. et al.: Fuel, 70, 559 (1991);

Applications Prometon-d3 (methoxy-d3) (CAS# 1219803-43-6) is a useful isotopically labeled research compound.

Applications Butyl 3-Formylcrotonate-D9 is a labelled analogue of Butyl 3-Formylcrotonate (B809105).

Applications 4-n-Butylanisole-2,3,5,6-d4 (CAS# 1219804-78-0) is a useful isotopically labeled research compound.