Haletos orgânicos

<p>Applications 3,4-Dichloroaniline is used in the preparation of the herbicide propanil (P760840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlorophenol can be used in the regeneration of vegetal activated carbons.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H. et al.: Monatsh. Chem., 126, 1161 (1995); Dranca, I.: Environ. Eng. Man. J., 5, 203 (2006);<br></p>

<p>Applications 1H,1H,2H-Perfluoro-1-Octene (cas# 25291-17-2) is a useful research chemical.<br></p>

<p>Applications Bromochloroacetamide is a haloacetemide byproduct of nitrogenous disinfection agents at water purification plants in European and Asian countries.<br>References Kosaka, K. et al.: Water Res., 106, 470 (2016);<br></p>

<p>Applications An intermediate for the preparation of Citalopram.<br></p>

<p>Applications 9-Bromononanol (cas# 55362-80-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorodecyltriethoxysilane is used in making thin film transistors, polyethersulfone membranes, and a superwettable Janus membrane.<br>References Zhu, Zhigao, et al.: J. of Membrane Sci., 563, 602-609 (2018); Khan, Aftab A., et al.: Separation and Purification Tech., 210, 20-28 (2019); Shih, Andy, et al.: MRS Adv., 3(33), 1877-1882 (2018)<br></p>

<p>Applications Hexyl chloroformate is used as a derivatizing agent in organic synthesis, and is also used as a reagent to synthesize Dabigatran (D100090), an oral thrombin inhibitor used to prevent venous thromboembolism.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eerenberg, E., et al.: Circulation, 124, 1573 (2011); Eriksson, B., et al.: Lancet, 370, 949 (2007); Maurino, V., et al.: J. Am. Soc. Mass Spec., 10, 1328 (1999); Simpson, J., et al.: J. Am. Soc. Mass Spec., 6, 525 (1995); van Ryn, J., et al.: Thromb. &amp; Haemo., 103, 1116 (2010)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Chloro-5-(1-chloro-1,3-dihydro-3-oxo-1-isobenzofuranyl)-benzenesulfonyl Chloride is a useful synthetic intermediate.<br></p>

<p>Applications DL-2,4-Diaminobutyric Acid Dihydrochloride (cas# 65427-54-5) is a useful research chemical.<br></p>

<p>Applications 4-Bromo-2-chlorophenol<br></p>

<p>Applications 1,4-Diaminobutane is known to affect the development of plant root systems, it’s inhibition resulting in a more dominant ‘tap’ root system. 1,4-Diaminobutane is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes.<br>References Ben-Hayyim G. et al.: FEBS Lett., 4, 145 (1994); Hwang, J. et al.: Eur. J. Med. Chem., 70, 315 (2013); Yari, A. et al.: J. Biomed. Mat. Res., 102A, 84 (2014);<br></p>

<p>Stability Temperature sensitive - closes readily. Store at -80°C<br>Applications Used for isolating bases by means of Reinecke's salt.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dudley, H., et al.: Biochem. J., 27, 157 (1933),<br></p>

<p>Applications (S)-4,4-Difluoro-N-(3-oxo-1-phenylpropyl)cyclohexanecarboxamide acts as a reagent in the synthesis of CCR5 antagonists which are used in HIV therapy and may also be relevant for the treatment of graft-vs.-host disease and Staphylococcus aureus infection.<br>References Asano, S., et al.: ACS Med. Chem. , 5, 133 (2014)<br></p>

<p>Applications 1-Decylamine Hydrochloride is used as a cationic surfactant with copper or cobalt. 1-Decylamine Hydrochloride has also been used in the preparation of lyotropic liquid crystals.<br>References Badawi, A.M., et. al.: J. Surfactants Deterg., 10, 243 (2007); Luk, Y., et. al.: Chem. Materials, 17, 4774 (2005)<br></p>

<p>Applications 2,4-Dichloro-3,5-dinitrobenzotrifluoride is a reagent used in the synthesis of kinesin spindle protein inhibitors. Potential use as an alternative to neurotoxic MT inhibitors.<br>References Dong, J. et al.: Eur. J. Med. Chem., 70, 427 (2013);<br></p>

<p>Applications Di-tert-butyldichlorosilane (cas# 18395-90-9) is a useful research chemical.<br></p>

<p>Applications 2,3,4,5,6-Pentabromophenol is used in the synthesis of alkyltrichlorosilane surface modifiers for biomedical applications. Also used in the synthesis of flame retardant polymers.<br>References Blaszykowski, C. et al.: Langmuir, 28, 2318 (2012); Alam, S. et al.: Ann. Tech. Conf. Soc. Plas. Engineers., 3, 2400 (2011);<br></p>

<p>Applications 2-Amino-6-(chloromethyl)-4(3H)-pteridinone is a reagent/intermediate used in the preparation of Folic Acid (F680300) and its derivatives.<br>References Qi, Y., et al.: Faming Zhuanli Shenqing. CN 103755706 A 20140430. Apr 30, 2014;<br></p>

<p>Applications 2-Chloroethyl Methyl Ether is used as a reagent in the synthesis of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)<br></p>

<p>Applications Di-β,β'-Chloroethylphosphoric Acid, is a dialkyl hydrogen phosphates, that can undergo the electrophilic trifluor- omethylation to produce trifluoromethyl phosphates in order to increase the lipophilicity of functional groups.<br>References Santschi, N., et al.: J. Fluorine Chem., 135, 83 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(3-Chloropropyl)theobromine (cas# 74409-52-2) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Chlorotrimethylsilane have been used in the preparation of volatile derivatives of a wide range of compounds for GC analysis. Chlorotrimethylsilane has been used for silylation and as a protection group in the process of various organic synthesis.<br> E0<br>References Casimiro, M., et al.: Org. Lett., 15, 2378 (2013); Lifchits, O., et al.: J. Am. Chem. Soc., 135, 6677 (2013);<br></p>

<p>Stability Light Sensitive<br>Applications 3-Chlorocyclohexene (cas# 2441-97-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Ethoxybenzamidine hydrochloride is an impurity of Vardenafil (diHCl salt: V098001), a phosphodiesterase type 5 inhibitor that is used to treat men of varying aetiology with erectile dysfunction.<br>References Hellstrom, W., et al.: J. Andro., 23, 763 (2002); Keating, G. &amp; Scott, L.: Drugs, 63, 2673 (2003); Krishnaiah, C., et al.: Anal. Chem. Ind. J., 8, 284 (2009); Porst, H., et al.: Int. J. Imp. Res., 13, 192 (2001)<br></p>

<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications Isopropylamine Hydrochloride is an intermediate in the synthesis of 1-Cyano-3-isopropylguanidine (C955800).<br>References Jensen, N., et al.: J. Med. Chem., 44, 3925 (2001), Paci, A., et al.: J. Pharm. Biomed. Anal., 27, 1 (2002),<br></p>

<p>Applications Ethenesulfonyl chloride is a useful reactant for the preparation of oral quinoline-based ALDH1A1 inhibitors as potential antitumor agents.<br>References Yang, SM., et al.: J. Med. Chem., 61, 4883-4903 (2018);<br></p>

<p>Applications 7-(2-Chloroethyl)theophylline (cas# 5878-61-5) is a useful research chemical.<br></p>

<p>Applications 2-CHLOROTOLUENE (cas# 95-49-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications epi-5-Fluoro ADB is an analog of fluoronatied ADB-PINACA an analog of AKB48 in which the adamantyl group has been replaced with 1-amino-3,3-dimethyl-1-oxobutan-2-yl (ADB). epi-5-Fluoro ADB is a synthetic cannabinoid. Synthetic Cannabinoids<br>References Uchiyama, N., et al.: Forensic Toxicol., 30, 114 (2012)<br></p>

<p>Applications Ethylenebis(tetrabromophthalimide) is an additive fire retardant that is added to a polymer mixture to produce a blend. Ethylenebis(tetrabromophthalimide) is used in high impact polystyrene (HIPS), polyethylene, polypropylene, thermoplastic polyesters, polyamide, ethylene propylene-diene terpolymers (EPDM rubbers) and other synthetic rubbers, polycarbonate, ethylene copolymers, ionomer resins, epoxies, and textile treatments.<br>References Clausen, E., et al.: Anal. Chem., 327, 297 (1987);<br></p>

<p>Stability Hygroscopic<br>Applications Perfluorobutylphosphonic Acid, is a surfactant or antifoaming agent.<br></p>

<p>Stability Moisture Sensitive<br>Applications Pentachloroacetone is a disinfection byproduct.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jeong, C., et al.: Environ. Sci. Technol., 46, 12120 (2012); Colman, J., et al.: Toxicol. Appl. Pharm., 254, 100 (2011)<br></p>

<p>Applications Phosphorus(V) Oxybromide is a reagent used in the preparation of phosphoryl halide for N-protection of amino acids using group assisted purification (GAP). Phosphorus(V) Oxybromide is a brominating agent.<br>References An, G., et al.: Heterocycles, 90, 344 (2015); Guo, J., et al.: Hebei Gongye Daxue Xuebao, 40, 57 (2011); Golding, D., et al.: J. Org. Chem., 12, 293 (1947)<br></p>

<p>Applications α-Chlorobenzyl 4-Fluorophenyl Ketone is derived from Benzyl 4-Fluorophenyl Ketone (B279785), which is used in preparation and evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors.<br>References Singh, S. et al.: Bioorg. Med. Chem., 12, 1881 (2004);<br></p>

<p>Applications 2-Amino-4-chlorobenzenethiol is used as reagent in the synthesis of several organic compounds including that of MHY908 which is an inhibitor of melanogenesis and can potentially be used in the prevention and treatment of pigmentation disorders. Also used in the synthesis of γ-lactam analogs of prostaglandin E2 which may act as EP4 agonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Park, M., et al.: Arch. Pharm. Res., 38, 505 (2015); Kambe, T., et al.: Bioorgan. Med. Chem., 20, 3502 (2012);<br></p>

<p>Applications 5-Bromo-2-thiophenecarboxaldehyde is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.<br>References Prabhu, V.V., et al.: J. Immunotoxicol., 9, 341 (2012);<br></p>

<p>Applications 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid is a photoreactive aromatic diazirine.<br>References Wiedmann, M .; J. Cell biol.; 104, 201 (1987).<br></p>

<p>Impurity Fluorouracil EP Impurity E<br>Applications Used for the experimental and clinical treatment of neoplastic and viral diseases. Fluorouracil EP Impurity E.<br>References Yu, H., et al.: J. Biol. Chem., 268, 15935 (1993), Staleva, L., et al.: Mutat. Res., 370, 81(1996), Harris, V., et al.: J. Mol. Biol., 326, 1389 (2003)<br></p>

<p>Applications 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Fluorobenzene, is an aryl fluorinated building block used in various chemical synthesis. Fluorobenzene is a useful solvent for highly reactive species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Flood, D. T., Org. Synth.; Coll., 2, 295 (1943); Perutz, R. N., et al.: Compeh. Organometallic Chem., 1, 725 (2007);<br></p>

<p>Stability Moisture Sensitive<br>Applications 1,1,1-Trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (cas# 82113-65-3) is a useful research chemical.<br></p>

<p>Applications (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.<br>References Wang, X., et al.: Org. Lett., 16, 4090 (2014);<br></p>

<p>Applications 1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities.<br>References Barasch, D., et al.: Eur. J. Med. Chem., 34, 597 (1999)<br></p>

<p>Applications 1-Chloro-6-iodohexane is used in studies to demonstrate the direct reduction of 1-Bromo-6-chlorohexane/1-Chloro-6-iodohexane at silver cathodes in Dimethylformamide.<br>References Rose, J.A., et al.: ?Electrochim. Acta, 218, 311-317 (2016)<br></p>

<p>Applications Difluoroacetic acid<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Chloro-2,5-dimethoxyaniline was an analyte identified in a screening study of electronic nicotine delivery systems (ENDS), which are regulated tobacco products.<br>References Hung, P. H., et al.: J. Applied Toxic., 40, 1566 (2020)<br></p>

<p>Stability Unstable in Solution<br>Applications 2-(Trimethylsilyl)ethoxymethyl chloride is mostly used in organic synthesis to protect hydroxyl functionalities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lipshutz, B. &amp; Miller, T.: Tetrahedron Lett., 30, 7149 (1989); Wada, T., et al.: Tetrahedron Lett., 36, 1683 (1995)<br></p>

<p>Applications 2,3-Dibromopropionamide (cas# 15102-42-8) is a useful research chemical.<br></p>

<p>Applications 3-Chloropropionic Acid (cas# 107-94-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Dibromoformaldoxime is a reagent that undergoes cycloaddition with alkynes to prepare substituted 3-bromo-isoxazoles in high yield.<br>References Chiarino, D., et al.: J. Heterocyclic Chem., 24, 43 (1987); De Amici, M., et al.: J. Org. Chem., 54, 2646 (1989); Castelhano, A., et al.: 16, 335 (1988).<br></p>

<p>Impurity Bupropion 2-Bromo Impurity (Related Compound G)<br>Applications 3’-Chloro-2-bromopropiophenone (cas# 34911-51-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4,5,5,6,6,7,7,7-nonafluoroheptan-1-ol (cas# 83310-97-8) is a useful research chemical.<br></p>

<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>

<p>Applications Nonanoyl Chloride is used in the synthesis of immunosuppressants involving 2-aminoethanols and aminopropane-1,2-diols. Also used in the synthesis of Vanilloids with antinociceptive and antiinflammatory compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiuchi, M. et al.: J. Med. Chem., 43, 2946 (2000); Janusz, J. et al.: J. Med. Chem., 36, 2595 (1993);<br></p>

<p>Applications Methyl 2,3-dichlorobenzoate<br></p>

<p>Applications 2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).<br>References McClay, K. et al.: Appl. Environ. Microbiol., 73, 6870 (2007); David, F<br></p>

<p>Applications 2,4,5,6-Tetrachloro-m-xylene, is an intermediate for the synthesis of pesticides and metabolites. It can also be used for the preparation of Quinol nitrates.<br>References Suzuki, H., et al.: J. Chem. Soci. Comm., 51 (1957); Snyder, J. L., et al.: Anal. Chem., 64, 1940 (1992);<br></p>

<p>Applications Chloramine-T Trihydrate is used as a safe and convenient electrocyclisation (oxidizing) agent in the preparation of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mal, S., et al.: Tetrahedron Lett., 56, 2896-2901 (2015)<br></p>

<p>Applications Methyl 3-bromo-4-hydroxybenzoate<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications 5-Bromoacetyl-2-hydroxybenzamide is a reagent used in the synthesis of bisthiazole derivatives and novel 7-methylguanine derivatives targeting influenza polymerase binding domains.<br>References Pautus, S. et al.: J. Med. Chem., 56, 8915 (2013); Araniciu, C. et al.: Revista. Chim., 64, 1067 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications Methyltin Trichloride is used in the synthesis of metallasilesesquiloxanes used for their important application to silica surfaces. Also used in the preparation of organotin(IV) complexes showing antibacterial activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feher, F. et al.: J. Am. Chem. Soc., 114, 3859 (1992); Salam, M., Heteroatom Chem., 24, 43 (2013);<br></p>

<p>Applications 3,5-Dinitrochlorobenzene is used to study strength and directionality of halogen bond are co-detected by the magnitude and size of the σ-hole.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kolar, M., et al.: Phys. Chem. Chem. Phys., 16, 9987 (2014);<br></p>

<p>Applications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)<br></p>

<p>Applications 2,3,5,6-Tetrachlorophenol is used in the study of the toxicity of halogenated phenols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References He, G., et al.: Procedia Eng., 43, 204 (2012)<br></p>

<p>Applications Ethyl 2,3-Dibromopropanoate is a building block that has been used as a catalyst for the polymerization of ethyl acrylate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakota, N., et. al.: Kogyo Kagaku Zasshi, 72, 975 (1969)<br></p>

<p>Applications Anticonvulsant against audiogenic convulsion.<br>References Kim, K., et al.: J. Med. Chem., 51, 5330 (2008), Ruel, R., et al.: Bioorg. Med. Chem. Lett., 18, 2985 (2008),<br></p>

<p>Applications 1H,1H,2H-Perfluoro-1-decene (cas# 21652-58-4) is a useful research chemical.<br></p>

<p>Applications Octyl Bromide, is a versatile halogenated building block in chemical synthesis. It has also industrial applications. It is used in the preparation of fluorous polymers, which serve as a surface modifier and an emulsifier.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Golling, F. E., et al.: Poly. Prep.(Amer. Chem. Soci. Div. Poly. Chem), 52, 735 (2011);<br></p>

<p>Applications 3-(2,2,2-trifluoroethoxy)prop-1-yne (cas# 1481-06-7) is a useful research chemical.<br></p>

<p>Applications 2-Iodoxybenzoic Acid is used in the oxidation of alcohols in organic synthesis. It is also frequently used in the preparation of Dess-Martin periodinane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Frigerio, M. et al.: J. Org. Chem., 60, 7272 (1995); Ireland, R. et al.: J. Org. Chem., 58, 2899 (1993);<br></p>

<p>Applications Intermediate in the preparation of imidazole antifungal agents.<br>References Albet, C. et al.; J. Pharmaceut. Biomed. 10, 205 (1992); Raga, M. et al.; Eur. J. Med. Chem. 21, 329 (1986)<br></p>

<p>Stability Hygroscopic<br>Applications N-(2-Chloroethyl)-1,2-ethanediamine Dihydrochloride is an analog of 2-(2-Aminoethylamino)ethanol (A608990); a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Also used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013)<br></p>

<p>Applications Fluoranthene is a commonly occurring environmental pollutant and can be classified as either a tumour initiator or a cocarcinogen in humans. Fluoranthene is widely used as an intermediate to synthesize fluorescent dyes. This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hecht, S., et al.: Carcinogenesis, 16, 1433 (1995); Storer, J., et al.: Arch. Dermatol., 120, 874 (1984); Ma, X., et al.: Dyes Pigments, 82, 353 (2009)<br></p>

<p>Applications 4-Chlorobenzal Chloride is an impurity that is formed in the synthesis of Benoxaprofen (B165300); a non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cockerill, A.F., et al.: J. Chromatogr., 129, 339 (1976); Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003); Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007); Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009)<br></p>

<p>Applications 4-Bromophenol is used as a reagent in Stille reactions.<br>References Littke, A.F. et al.: J. Am. Chem. Soc., 124, 6343 (2002);<br></p>

<p>Applications 2-hydroxy-5-iodobenzoic Acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labelled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.<br>References Tu, Z. et al.: J. Med. Chem., 50, 3194 (2007); Sellarajah, S. et al.: J. Med. Chem., 47, 5515 (2004);<br></p>

<p>Applications 4-Fluoroephedrine (cas# 63009-92-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.<br>References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009<br></p>

<p>Stability Moisture sensitive<br>Applications Diisopropyl Phosphorochloridate is a phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications N-Phenyl-3-(trifluoromethyl)aniline (cas# 101-23-5) is a useful research chemical.<br></p>

<p>Applications 2,3,4,6-Tetrachlorotoluene is a tetra-chlorinated derivative of toluene that is often used as a reference standard.<br></p>

<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>

<p>Applications 1,2,4-Tribromobenzene is a compound commonly used in organic synthesis reactions. 1,2,4-Tribromobenzene is hepatotoxic to rats, and is also toxic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dodd, D., et al.: Int. J. Toxicol., 31, 250 (2012); Szymanska, J.: Arch Toxicol., 72, 97 (1998)<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorooctyl-1-thiol acts as a reagent in the preparation, structure, and antitumor activity of dinuclear arene ruthenium thiolato complexes with fluorous side-chains. Reagent in the preparation of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders.<br>References Stibal, D., et al.: Inorganica Chimica Acta, 444, 51 (2016); Durand, G., et al.: Bioorg. Med. Chem. Lett., 13, 859 (2003)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Ethylbutyl Chloroformate is a possible impurity from the synthesis of Dabigatran etexilate mesylate (D100150).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zheng, Y., et al.: Org. Proc. Res. Devel., 18, 744 (2014)<br></p>

<p>Applications Benzo[j]fluoranthene is a polycyclic aromatic hydrocarbon that has tumour initiating activity and can be found in soot, oil, water and soil extracts as a common pollutant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References LaVole, E., et al.: Carcinogenesis, 3, 49 (1982); Nadal, M., et al.: Environ. Pollut., 132, 1 (2004); White, P. &amp; Rasmussen, J.: Mutat. Res., 410, 223 (1998); Wornat, M., et al.: Environ. Sci. Technol., 35, 1943 (2001)<br></p>

<p>Applications 1,1-Dichloro-2-propanone is a disinfection byproduct in drinking water. It may cause bladder cancer and other adverse health effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Farre, M., et al.: Water Sci. Tehnol., 12, 573 (2012); Catherine, M., et al.: Water Res., 47, 3231 (2013); Neale, P., et al.: Environ. Sci. Technol., 46, 10317 (2012)<br></p>

<p>Applications 2-Chloro-4,5-dinitro-toluene (cas# 56136-79-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(Dimethylphosphinyl)benzenamine Hydrochloride is the salt form of 4-(Dimethylphosphinyl)benzenamine, a reactant in the preparation of 9-(arenethenyl)purines as dual Src/Abl kinase inhibitors.<br>References Huang, Wei-Sheng, et al.: J. of Med. Chem., 52(15), 4743-4756 (2009)<br></p>

<p>Applications Methyl 2-Bromomethylbenzoate is a reactant in the preparation of Methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate with neuroprotective activity.<br>References Zhong, Y., et. al.: Chin. J. Struct. Chem., 33, 1096 (2014)<br></p>