Haletos orgânicos

<p>Applications 3-Chlorodiphenylamine (cas# 101-17-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications n-Undecanoyl Chloride is an analog of Heptanoyl Chloride (H281235), which is used in the synthesis of novel class of 2-Aminopyrimidines as CDK1 and CDK2 inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Samanta, R., et al.: Org. Lett., 14, 5518 (2012); Sabbah, M., et al.: Bioorg. Med. Chem., 20, 4727 (2012)<br></p>

<p>Applications Octyl Bromide, is a versatile halogenated building block in chemical synthesis. It has also industrial applications. It is used in the preparation of fluorous polymers, which serve as a surface modifier and an emulsifier.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Golling, F. E., et al.: Poly. Prep.(Amer. Chem. Soci. Div. Poly. Chem), 52, 735 (2011);<br></p>

<p>Impurity Adamantane Impurity 3<br>Applications 1-Ethyl-3-bromoadamantane have been used in the synthesis of 1-adamantyloxyalkanols. Adamantane Impurity 3<br>References Reznikov, A.N., et al.: Russ. J. Org. Chem., 46, 1741 (2010); Henkel, J.G., et al.: J. Med. Chem., 25, 51 (1982);<br></p>

<p>Applications Decafluorobiphenyl is used for step−growth polymers synthesis (1).<br>References (1) Deck, P. A. and Maiorana, C. R. Macromolecules 34, 9 (2001)<br></p>

<p>Applications Fluoro phosphates useful as surfactants, surface treating agents, leveling agents.<br></p>

<p>Stability Hygroscopic<br>Applications 2,2,4,4,6,6-Hexakis(2,2,3,3-tetrafluoropropoxy)-2λ5,4λ5,6λ5-1,3,5,2,4,6-triazatriphosphorine is a component of Ultramark 1621 which is a useful calibration compound for negative and positive ion fast-atom bombardment (FAB) high-resolution mass spectrometry.<br>References Jiang, L., et al.: J. Am. Soc. Mass Spec., 3, 842 (1992)<br></p>

<p>Applications Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.<br>References Selassie, C.D. et al.: J. Med. Chem., 33, 1914 (1990); Venkatachalam, M.A et al.: Kidney Int., 49, 449 (1996);<br></p>

<p>Applications 2-Bromoethanol is an widely used intermediate in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tian, Z., et al.: Int. J. Quant. Chem., 111, 631 (2011); Thayer, F.K., et al.: Org. Syntheses., 6, (1926);<br></p>

<p>Applications 1-Bromo-2-butyne is used in the synthesis of six to eight annulated ring compounds in reactions with indoles. It is also used in the preparation of Pseudopterane (+/-)-Kallolide B, a marine natural product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferrer, C. et al.: Chem. A. Eur. J. et al.: 13, 1358 (2007); Marshall, J. et al.: J. Org. Chem., 60, 796 (1995);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Bromomethylbenzil (cas# 18189-19-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,2,4-Triaminobenzene Dihydrochloride is a useful reagent for making multicolor fluorescent carbon dots that can be detected via white-​light-​emitting diodes and water.<br>References Kumari, R., et al.: Langmuir, 36, 5287 (2020)<br></p>

<p>Applications Bromocyclobutane<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 9-Hydroxyfluorene is a wake promoting agent and is considered as the next generation anti-narcolepsy drug. It is also a potential environmental carcinogen.<br>References Dunn, D., et al.: Bioorg. Med. Chem. Lett., 22, 3751 (2012); Clark, J., et al.: Environ. Res., 117, 132 (2012); Li, F., et al.: Environ. Toxicol. Phar., 32, 373 (2011)<br></p>

<p>Stability Moisture Sensitive<br>Applications Benzoyl Chloride is used in the manufacturing of dye intermediates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glotzbach, C. et al.: J. Org. Chem., 78, 4410 (2013); Coskun, A. et al.: J. Am. Chem. Soc., 127, 10464 (2005);<br></p>

<p>Applications 3-(Methylamino)propanoic acid HCl<br></p>

<p>Applications benzo[b]fluoren-11-one (cas# 3074-03-1) is a useful research chemical.<br></p>

<p>Applications 4-Bromophenol is used as a reagent in Stille reactions.<br>References Littke, A.F. et al.: J. Am. Chem. Soc., 124, 6343 (2002);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4,4'-Dimethoxytrityl Chloride (cas# 40615-36-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Bromo-4,5-dimethoxybenzoic Acid (cas# 6286-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4,5-Trifluorobenzoic Acid is a useful synthetic intermediate. It can be used to synthesize quinolone antibacterial agnts.<br>References Sanchez, J., et al.: J. Med. Chem., 31, 983 (1988); Tran, T., et al.: Bioorg. Med. Chem. Lett., 14, 4405 (2004)<br></p>

<p>Applications 4-[(2-chloroacetyl)amino]benzoic acid (cas# 4596-39-8) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Tri-n-octylchlorotin is an octyltin compound used to study the growth and fatty acid of the microscopic fungus Cochliobolus lunatus. It is also an organotin reagents used to covalently functionalize oxide nanostructures and multi-walled C nanotubes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Felczak, A., et al.: Process Biochem., 49, 295-300 (2014); Gomathi, A., et al.: J. Mater. Chem., 19, 988-995 (2009);<br></p>

<p>Applications Ethyl 4-Bromo-2-(methoxyimino)-3-oxobutyrate is an intermediate used in the synthesis of some thiophene analogs as anti-inflammatory agents.<br>References Pillai, A., et al.: Bioorg. Med. Chem., 13, 1275 (2005)<br></p>

<p>Applications 2-(2-chloroethoxy)ethylphosphonic acid, tech. is used in biological study for studying the composition of technical ethephon.<br>References Segall, Y. et al.: Jou. of Agr. and Foo. Che., 39(2), 380-5, (1991)<br></p>

<p>Applications 2-Chlorobenzonitrile is an activated aryl chloride that is commonly used in reactions that involve the Palladium-catalyzed direct arylation of heteroaromatics (e.g. 3-aminopicolinic acid [A627800]). 2-Chlorobenzonitrile and its substituted derivatives (e.g. 2,3-dichloro-6-nitrobenzonitrile [2112-22-3]) also have potential anti-inflammatory properties.<br>References Andreu, M., et al.: Chem. Commun., 24, 2475 (2000); Hellman, W., et al.: J. Med. Chem., 21, 906 (1978); Roy, D., et al.: ACS Catal., 2, 1033 (2012);<br></p>

<p>Applications Ethyl 4-Bromobutanoate is a building block which has been used as a reactant for the preparation of firefly luciferase inhibitor-conjugated peptide derivatives.<br>References Poutiainen, P.K., et. al.: Bioconjugate Chem., 25, 4 (2014)<br></p>

<p>Stability Moisture Sensitive<br>Applications 3,5-Dinitrobenzoyl Chloride was used as a derivatization agent for high performance liquid chromatographic analysis of several compounds including polyamines and acteylated derivatives, taurine and hypotaurine and biogenic amines in fermented foods. It was also used in the synthesis of several organic compounds including that of a novel starch derivative which has adsorption property for creatinine and may therefore be useful in treatment of renal failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirschbaum, J., et al.: J. Chromatogr A., 881, 517 (2000); Wongyai, S., et al.: Biomed. Chromatogr., 2, 254 (1988); Masuoka, N., et al.: J. Chromatogr B., 660, 31 (1994); Jiu-gao, Y., et al.: Acta Pharm. Sin., 38, 191 (2003);<br></p>

<p>Applications Hydrogen Tetrafluoroborate(1-) is a useful building block for organic synthesis.<br>References Ohkuma, T., et al.: Journal of the American Chemical Society., 218, 8724 (2006)<br></p>

<p>Applications 3,5-Diiodothyronamine Hydrobromide is an intermediate in the synthesis of Thyronamines and related analogues.<br>References Hart, M. E., et al.: J. Med. Chem., 49, 1101 (2006);<br></p>

<p>Impurity Mesalazine EP Impurity M<br>Applications 2-Chloro-5-nitrobenzoic Acid is used in the synthesis of sesquiterpenoids as potential antibacterial compounds. Also used in the synthesis of substituted phenyl oxazoles as novel LSD1 inhibitors with antiproliferative activity. In addition it’s used to synthesize cathespin L inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dulla, B. et al.: Org. Biomol. Chem., 11, 3103 (2013); Torkar, A. et al.: Bioorg. Med. Chem. Lett., 23, 2968 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications 1,1,1-Trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (cas# 82113-65-3) is a useful research chemical.<br></p>

<p>Applications 2,6-Difluorobenzoylacetonitrile is used in the synthesis of thienodiazepinones which can have poor central nervous system depressant activity.<br>References Binder, D., et al.: Arch. Pharm., 313, 587 (1980)<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.<br>References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);<br></p>

<p>Applications 2-Aminobenzotrifluoride is used as a reagent to synthesize thiohydrazides that act as effective antibacterial remedies for chlamydia. 2-Aminobenzotrifluoride is also used as a reagent to synthesize substituted 2-benzothiazolamines which have anticonvulsant activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hays, S., et al.: J. Pharm. Sci., 83, 1425 (1994); Yarovenko, V., et al.: J. Chem. Chemical Eng., 4, 55 (2010)<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>

<p>Applications PROP-2-EN-1-AMINE HCL (cas# 10017-11-5) is a useful research chemical.<br></p>

<p>Applications 1-Bromonapthalene is used in the preparation of N-aryl imidazoles and diaryl ethers. Also used in the preparations of glutathione peroxidase-like antioxidant activity of diaryl diselenides.<br>References Ghorbani-Vaghei, R. et al.: Tetrahedron Lett., 54, 7095 (2013); Mugesh, G. et al.: J. Am. Chem. Soc., 123, 839 (2001);<br></p>

<p>Stability Moisture Sensitive<br>Applications Dimethyl chlorothiophosphate is an organophosphorus reagent that is used to synthesize phosphorus analogues of γ-aminobutyric acid, compounds that exhibit anticonvulsant properties. Dimethyl chlorothiophosphate is also used as a reagent to synthesize Parathion (P192220), a widely used pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cates, L., et al.: J. Med. Chem., 27, 654 (1984); DeBruin, K. &amp; Boros, E.: J. Org. Chem., 55, 609 (1990); Hall, S.: J. Am. Chem. Soci., 72, 2768 (1950); Kotronarou, A. &amp; Hoffmann, M.: Env. Sci. Tech., 26, 1460 (1992)<br></p>

<p>Applications 1,3-Dichloro-5,5-dimethylhydantoin is used as a reagent in the synthesis of macrolactonolides which can be used as potential antiinflammatory drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013)<br></p>

<p>Applications 2-Chloro-1,5-hexadiene is a reagent in the conversion of zirconabicycles into bicyclic enones via carbonylation.<br>References Negishi, E., et al.: J. Am. Chem. Soc., 111, 3336-46 (1989)<br></p>

<p>Applications 4-(Dimethylphosphinyl)benzenamine Hydrochloride is the salt form of 4-(Dimethylphosphinyl)benzenamine, a reactant in the preparation of 9-(arenethenyl)purines as dual Src/Abl kinase inhibitors.<br>References Huang, Wei-Sheng, et al.: J. of Med. Chem., 52(15), 4743-4756 (2009)<br></p>

<p>Applications A valuable tool in studies of cellular organelles and oligomeric enzymes, using the techniques of protein-protein cross-linking. It may also be used to introduce reactive sulfhydryl groups into proteins for subsequent reaction with alkylating agents or heavy metal compounds.<br>References Perham, R.N. &amp; Thomas, J.O.: J. Mol. Biol., 62, 415 (1971), Jue, R., et al: Biochemistry, 17, 5399 (1978)<br></p>

<p>Applications N,N-Dimethyl-3-phenylpentan-3-amine Hydrochloride is a useful research chemical.<br></p>

<p>Applications 1-Bromobenzene, is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);<br></p>

<p>Applications 2-tert-butyl-2-[2-(4-chlorophenyl)ethyl]oxirane (cas# 80443-63-6) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications An intermediate in the synthesis of Terbinafine (T107500).<br></p>

<p>Applications 2,4,6-Tribromoanisole is haloanisole often present in wine. 2,4,6-Tribromoanisole is one of the main agent responsible for the musty odor in wine sample<br>References Sanvicens, N. et al.: J. Agric. Food Chem., 54, 9176 (2006); Copete, M.L. et al.: Food Add. Contam. Part A Chem. Anal. Cont. Risk Assess., 26, 32 (209);<br></p>

<p>Applications Methoxyacetyl chloride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Copper Hexafluorosilicate is a useful compound in metal-organic material synthesis.<br>References Nugent, P., et al.: Natrue, 495, 80 (2013);<br></p>

<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>

<p>Stability Hygroscopic<br>Applications Quaternary ammonium salts useful as paint strippers, foaming stabilizers, and bactericidal lotions.<br>References Bhattacharya, S., et al.: Biochemistry, 37, 7764 (1998), Raspaud, E., et al.: Biophys. J., 74, 381 (1998), Asgatay, S., et al.: Int. J. Pharm., 285, 121 (2004), Goracci, L., et al.: ChemBioChem., 6, 197 (2005),<br></p>

<p>Impurity Mesalazine EP Impurity L<br>Applications The toxicity of halogenated benzoic acids was found to be directly related to the compound's hydrophobicity. Toxicity and quantitative structure-activity relationships of benzoic acids to Pseudokirchneriella subcapitata.<br>References Moore, D., et al.: Environ. Toxicol. Chem., 16, 794 (1997), Zhao, Y., et al.: Sci. Total Environ., 216, 205 (1998), Fiorentino, A., et al.: J. Agric.Food Chem., 51, 1005 (2003),<br></p>

<p>Applications Butylamine Hydrochloride is a miscellaneous reagent used in the synthesis of benzamides for the synthesis of various drugs and polymers.<br>References Bantreil, X. et al.: Eur. J. Org. Chem., 2015, 416 (2015);<br></p>

<p>Applications 4-Chloropropiophenone is a useful synthetic intermediate. It can be used to prepare 4-Chloro Cathinone. It can also be used to synthesize bupropion (B689625) analogs.<br>References Carroll, F., et al.: J. Med. Chem., 52, 6768 (2009)<br></p>

<p>Applications Ethylenebis(tetrabromophthalimide) is an additive fire retardant that is added to a polymer mixture to produce a blend. Ethylenebis(tetrabromophthalimide) is used in high impact polystyrene (HIPS), polyethylene, polypropylene, thermoplastic polyesters, polyamide, ethylene propylene-diene terpolymers (EPDM rubbers) and other synthetic rubbers, polycarbonate, ethylene copolymers, ionomer resins, epoxies, and textile treatments.<br>References Clausen, E., et al.: Anal. Chem., 327, 297 (1987);<br></p>

<p>Applications Chloramine-T Trihydrate is used as a safe and convenient electrocyclisation (oxidizing) agent in the preparation of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mal, S., et al.: Tetrahedron Lett., 56, 2896-2901 (2015)<br></p>

<p>Applications Tetrachlorohydroquinone is a chlorinated hydroquinone compound used as an analytical standard.<br></p>

<p>Applications An intermediate for the preparation of Citalopram.<br></p>

<p>Applications (3-trans-Chloroallyl)oxyamine is used as a reagent in the preparation of 5-(dioxabicyclohept-6-yl)cyclohexenone oxime ether as hericides and plant growth regulators.<br>References Rheinheimer, J., et al.: PCT Int. Appl., 1998:490643 (1998)<br></p>

<p>Applications 2,4-Dichloro-3,5-dinitrobenzotrifluoride is a reagent used in the synthesis of kinesin spindle protein inhibitors. Potential use as an alternative to neurotoxic MT inhibitors.<br>References Dong, J. et al.: Eur. J. Med. Chem., 70, 427 (2013);<br></p>

<p>Applications It is used in a new method for conjugation of carbohydrates to proteins using an aminooxy-thiol heterobifunctional linker.<br>References Tietze, L., et al.: Bioconjugate Chem., 2, 148 (1991), Peeters, C., et al.: Infect. Immun., 60, 1826 (1992), Brask, J., et al.: J. Pept. Sci., 6, 290 (2000),<br></p>

<p>Stability Very Volatile<br>Applications 1,1-Dichloroethane is used as a chemical solvent in the preparation of precursors of quinolizine, isoquinoline and indole alkaloids(1). Groundwater contaminant, DDT biodegredation product(2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Butler, E. et al.: Env. Sci. Tech. 2000, 34 (3), pp 422–429.2. Ren, L. et al.: Chemosphere. 2017 Feb;168:244-253.3. Grewal, J. et al.: J. Environ. Sci. Health. B. 2016 Dec;51(12):809-816.<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Applications 2,4,5,6-Tetrachloro-m-xylene, is an intermediate for the synthesis of pesticides and metabolites. It can also be used for the preparation of Quinol nitrates.<br>References Suzuki, H., et al.: J. Chem. Soci. Comm., 51 (1957); Snyder, J. L., et al.: Anal. Chem., 64, 1940 (1992);<br></p>

<p>Applications 2,3,4,5-Tetrachlorophenol is a halogenated phenol found in textiles and leather products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhu, Feng.: Pige Kexue Yu Gongcheng, 24(4), 65-72 (2014)<br></p>

<p>Applications 1-Chloro-4-(chlorophenylmethyl)benzene is used in the synthesis of novel benzhydrylpiperazine derivatives as cytotoxic compounds in the treatment of various cancers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gurdal, E. et al.: Drug Res., 63, 121 (2013); Yarim, M. et al.: Int. J. Mol. Sci., 13, 8071 (2013);<br></p>

<p>Impurity Azelastine EP Impurity E /Azelastine USP RC E<br>Applications Stilbene-related benzalphthalide derivative with with potential anti-HIV and leishmanicidal activity. It has anxiolytic effects and maybe useful in the development of a non-benzodiazepinic and non-nitrogenated antianxiety agents.An impurity arising in the synthesis of azelastine (A808250).<br>References Zamilpa, A. et al.: Bioorg. Med. Chem. Lett., 15, 3483 (2005); Bedoya, L.M. et al.: Bioorg. Med. Chem. Lett., 16, 4075 (2006); del Olmo, E. et al.: Bioorg. Med. Chem. Lett., 11, 2123 (2001);<br></p>

<p>Applications 2,4,5-trichlorobenzoic acid (cas# 50-82-8) is a useful research chemical.<br></p>

<p>Stability Moisture sensitive<br>Applications Diisopropyl Phosphorochloridate is a phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications 7-Bromoheptanoic Acid is a reagent that is used in the synthesis of N-Heptanoic Acid Tianeptine Disodium Salt (H281500) which are metabolite of Tianeptine (T436800), having psychostimulant, anti-ulcer and anti-emetic properties.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>

<p>Applications 1H,1H-Perfluorohexan-1-ol is a reagent in the synthesis of environmentally safer fluoroalkyl ether synthons.<br>References Lazzari, D., et al.: J. Fluorine. Chem., 156, 34 (2013)<br></p>

<p>Stability Hygroscopic<br>Applications N-(2-Chloroethyl)-1,2-ethanediamine Dihydrochloride is an analog of 2-(2-Aminoethylamino)ethanol (A608990); a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Also used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013)<br></p>

<p>Applications 6,8-Dichloro-octanoate is an Intermediate in the synthesis of α-Lipoic acid (L468750) and its derivatives.<br>References Zhang, S.J. et al: Bioorg. Medn. Chem. Letters., 20, 3078 (2010);<br></p>

<p>Applications Carboxymethoxyamine Hemihydrochloride (cas# 2921-14-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Nonanoyl Chloride is used in the synthesis of immunosuppressants involving 2-aminoethanols and aminopropane-1,2-diols. Also used in the synthesis of Vanilloids with antinociceptive and antiinflammatory compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiuchi, M. et al.: J. Med. Chem., 43, 2946 (2000); Janusz, J. et al.: J. Med. Chem., 36, 2595 (1993);<br></p>

<p>Applications 2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).<br>References McClay, K. et al.: Appl. Environ. Microbiol., 73, 6870 (2007); David, F<br></p>

<p>Applications 9-Bromononanol (cas# 55362-80-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Bromo-2,2-dichloroacetamide is a byproduct produced from water purifciation processes.<br>References Chuang, Y. et al.: Env. Sci. Tech., 53, 3729 (2019)<br></p>

<p>Applications 2,4,6-Tribromophenol a reagent used in industrial synthesis of compounds and pharmaceuticals. It is used in the synthesis of anti-HIV candidates. Identified as a metabolic impurity of industrial chemical runoff in humans and wildlife.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ludovici, D. et al.: Bioorg. Med. Chem. Lett., 11, 2229, (2001); Hovander, L. et al.: Arch. Env. Cont. Toxicol., 42, 105 (2002);<br></p>

<p>Applications 2-Amino-3,5-dibromobenzoic acid (cas# 609-85-8) is a useful research chemical.<br></p>

<p>Applications Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol<br>References Kitagawa, M., et al.: Chem. Pharm. Bull., 39, 2681 (1991), Keller, T., et al.: Chem. Pharm. Bull., 49, 1009 (2001),<br></p>

<p>Applications 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone is used in the synthesis of acid chloride phenylhydrazones in a broad-spectrum anthelmintic series.<br>References Rector, D. et al.: J. Med. Chem., 24, 532 (1981);<br></p>

<p>Applications Iodosobenzene (cas# 536-80-1) is a useful research chemical.<br></p>

<p>Applications 1-Bromo-2-(4-bromophenyl)ethylene (contains cis isomer) (cas# 778641-02-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 12-Chlorododecanoic Acid is used via animation to synthesize α-Amino dodecanoic acid (ADA); Also, it is derived from 12-Hydroxylauric Acid (H943775), which is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.<br>References Shi, X., et al.: Jingxi Huagong, 30, 911-914 (2013); Kubienova, L., et. al.: Biochimie, 95, 889 (2013)<br></p>

<p>Applications 2-[(Chloroacetyl)amino]benzoic Acid is used to prepare (thiazolyl)arylquinazolinone derivatives via cyclocondensation.<br>References Giri, R., et al.: Eur. J. Med. Chem., 44, 2184 (2009);<br></p>

<p>Applications 2-Amino-3-(2-chlorobenzoyl)thiophene is a useful compound for the synthetic process of Brotizolam (B689280(M)), which is a hypnotic and a sedative.<br>References Du, D. P., et al.: Zhongguo Yaowu Huaxue Zazhi, 25, 280 (2015); Sato, T., et al.: J. Med. Chem., 51, 7705 (2008); Nishino, T., et al.: J. Pharmacol. Sci., 107, 349 (2008); Yamashiro, T., et al.: J. Clin. Pharm, Ther., 33, 273 (2008); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)<br></p>

<p>Applications 1-Decylamine Hydrochloride is used as a cationic surfactant with copper or cobalt. 1-Decylamine Hydrochloride has also been used in the preparation of lyotropic liquid crystals.<br>References Badawi, A.M., et. al.: J. Surfactants Deterg., 10, 243 (2007); Luk, Y., et. al.: Chem. Materials, 17, 4774 (2005)<br></p>

<p>Applications 2-Ethoxybenzamidine hydrochloride is an impurity of Vardenafil (diHCl salt: V098001), a phosphodiesterase type 5 inhibitor that is used to treat men of varying aetiology with erectile dysfunction.<br>References Hellstrom, W., et al.: J. Andro., 23, 763 (2002); Keating, G. &amp; Scott, L.: Drugs, 63, 2673 (2003); Krishnaiah, C., et al.: Anal. Chem. Ind. J., 8, 284 (2009); Porst, H., et al.: Int. J. Imp. Res., 13, 192 (2001)<br></p>