Haletos orgânicos

<p>Applications Ethyl 3-bromopropionate<br></p>

<p>Applications 3-Chlorobenzene-1,2-diamine<br></p>

<p>Applications 1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities.<br>References Barasch, D., et al.: Eur. J. Med. Chem., 34, 597 (1999)<br></p>

<p>Applications Octyl Bromide, is a versatile halogenated building block in chemical synthesis. It has also industrial applications. It is used in the preparation of fluorous polymers, which serve as a surface modifier and an emulsifier.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Golling, F. E., et al.: Poly. Prep.(Amer. Chem. Soci. Div. Poly. Chem), 52, 735 (2011);<br></p>

<p>Applications 1,2,5,6,9,10-Hexabromocyclododecane is a flame retardant used in foamed polystyrene. One of the new POPs under the Stockholm Convention<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Larsen, E.R. et al.: J. Fire Sci., 4, 261 (1986);<br></p>

<p>Applications 3-Pyridylacetic Acid is a metabolite of Nicotine (N412420). 3-Pyridylacetic Acid is an antilipemic.<br>References Baer, T.A., et al.: J. Med. Chem., 16, 85 (1973); Kyerematen, G. A., et al.: Drug Metab. Dispos., 16, 125 (1988);<br></p>

<p>Applications Combinations of Bis(trichloromethyl)sulfone, (Hexachlorodimethyl sulfone) and 1,2-Dibromo-2,4-dicyanobutane are shown to have synergistic antimicrobial properties. The synergistic compounds may be used together with a third microbiocide to enhance the compound’s effectiveness against a wide variety of bacteria, molds, and yeasts and other microorganisms.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pearl, G., et al.: Curr. Top Med. Chem., 1, 247 (2001), Casalegno, M., et al.: Chem. Res. Toxicol., 18, 740 (2005), Toropov, A., et al.: Bioorg. Med. Chem., 14, 2779 (2006),<br></p>

<p>Applications tert-Butylhydrazine Hydrochloride is a a hydrazine compound used in organic synthesis for aromatic nucleophilic N-N exchange reaction. tert-Butylhydrazine Hydrochloride is also used in the preparation of insect growth regulator.<br>References Hojo, M. et al.: Synthesis, 6, 481 (1990); Zhang, J. et al.: Huax. Shijie, 36, 576 (1995);<br></p>

<p>Stability Moisture Sensitive (Reactive)<br>Applications Iodotrimethylsilane is a reagent used for cleaving ethers, esters, carbamates, ketals and lactones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heck, M., et al.: Tetrahedron Lett., 35, 5445 (1994); Hiral, G., et al.: Biorg. Med. Chem. Lett., 14, 2647 (2004)<br></p>

<p>Applications Fundamental starting material for organic synthesis.Metabolite of dibromobenzene in urine of rabbit.<br>References Ruzo, L., et al.: J. Agric. Food Chem., 24, 291 (1976),<br></p>

<p>Stability Moisture Sensitive<br>Applications Ethyl Trifluoroacetate is an intermediate used in the synthesis of various pharmaceutically active molecules and agricultural products. Ethyl Trifluoroacetate is also useful for the preparation of trifluoroacylated compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References HugenBerg, V., J. Fluorine. Chem., 131, 942 (2010); Belyakova, Z.V., et al.: Russ. J. Gen. Chem., 79, 2634 (2009); Wu, J.L., et al.: Jingxi. Huagong. Zhongjianti., 40, 64 (2010);<br></p>

<p>Applications 2-[(Chloroacetyl)amino]benzoic Acid is used to prepare (thiazolyl)arylquinazolinone derivatives via cyclocondensation.<br>References Giri, R., et al.: Eur. J. Med. Chem., 44, 2184 (2009);<br></p>

<p>Applications A reagent used in the preparation of prodrugs of diacidic nonpeptide angiotensin II antagonist as well as pyrrolothiazole platelet activating factor antagonist.<br>References Aungst, B.J. et al.: Pharmac. Res., 12, 763 (1996); Davidsen, S.K. et al.: J. Med. Chem., 37, 4423 (1994);<br></p>

<p>Stability Light Sensitive<br>Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.<br>References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)<br></p>

<p>Applications Ethyl difluoroacetate<br></p>

<p>Impurity Acemetacin EP Impurity A / Bezafibrate EP Impurity B<br>Applications A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>

<p>Applications 4-tert-Butyl-1,2-bis(chloromethyl)benzene is used as a reactant in the preparation of dihydronaphthalenes/naphthalenes via cobalt-catalyzed formal [4+2] cycloaddition of α,α'-dichloro-ortho-xylenes with alkynes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Komeyama, K., et al.: Angew. Chem. Int. Ed., 53, 11325 (2014);<br></p>

<p>Stability Hygroscopic<br>Applications Methylbenzethonium Chloride is an anti-leishmanial agent, in the treatment of leishmaniasis, a zoonotic infection affecting people in tropical regions.<br>References El-On, J. et al.: Exp. Parasitol., 116, 156 (2007); Peniche, A. et al.: Antimicrob. Agents. Chemother., 58, 78 (2014);<br></p>

<p>Applications 2,4-DINITROBENZYL BROMIDE (cas# 3013-38-5) is a useful research chemical.<br></p>

<p>Applications 3-Aminobenzamidine Dihydrochloride is a reactant that has been used in the synthesis of N-phenylamidines as selective inhibitors of human neuronal nitric oxide synthase.<br>References Collins, J.L., et. al.: J. Med. Chem., 41, 2858 (1998)<br></p>

<p>Applications Methyl 3-bromo-4-hydroxybenzoate<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Aminolevulinic Acid Hydrochloride (cas# CAS:5451-09-2) is a useful research chemical.<br></p>

<p>Applications 4-chlorocatechol was a major degradation product of 4-chloro-2-aminophenol (4C2AP)1. The degradation of 4-chlorocatechol was catalyzed by cphA-I enzyme2.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Quintelas, C., et al.: Environ. Sci. Pollut. Res. Int., 20, 1374 (2013); Costa, F., et al.: Biodegradation, 23, 81 (2012)<br></p>

<p>Applications 2-Bromo-2,2-dichloroacetamide is a byproduct produced from water purifciation processes.<br>References Chuang, Y. et al.: Env. Sci. Tech., 53, 3729 (2019)<br></p>

<p>Applications 4-Aminocatechol Hydrochloride is an acidic salt form of 4-Aminocatechol (A603280). 4-Aminocatechol is a phenol derivative with inhibitory activity against matrix metalloproteinase (MMP).<br>References Rubino, M.T. et al.: Arch. Pharm., 344, 557 (2011);<br></p>

<p>Applications Reagent used in the synthesis of cyhalothric pesticides and fungicides.<br>References Sun, C., et al.: Bioorg. Med. Chem., 14, 8574 (2006),<br></p>

<p>Applications α-Isopropylbenzylamine Hydrochloride is used in the synthetic preparation of arylalkylamines by addition of Grignard reagents to phosphorylaldimines.<br>References Zwierzak, A., Napieraj, A.: Synthesis, 6, 930 (1999)<br></p>

<p>Applications 3,5-Dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline (cas# 104147-32-2) is a useful research chemical.<br></p>

<p>Applications 3-[3-(trifluoromethyl)phenyl]propan-1-amine (cas# 104774-87-0) is a useful research chemical.<br></p>

<p>Applications 1-Chlorodecane is a reagent in the preparation of antimycobacterial agents. Also used in the synthesis of antimalarial atovaquone derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pathak, A. et al.: Bioorg. Med. Chem., 21, 1685 (2013); El Hage, S. et al.: Eur. J. Med. Chem., 44, 4778 (2009);<br></p>

<p>Stability Light Sensitive<br>Applications Iodoacetonitrile (cas# 624-75-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Chloro-2-(α-chlorophenylmethyl)benzene is used as a reagent in the synthesis of bifonazole analogs which have antibacterial and antifungal activities. It is also used in the preparation of diphenylpiperazine N-type calcium channel inhibitors.<br>References El Hage, S., et al.: Arch. Pharm., 344, 402 (2011); Pajouhesh, H., et al.: Bioorg. Med. Chem. Lett., 20, 1378 (2010)<br></p>

<p>Applications Reagent used in the preparation of carbonic anhydrase inhibitors.<br></p>

<p>Applications 2,2-Dibromopropanoic Acid is a disinfection byproduct (DBP) produced by disinfection of drinking water rich in bromide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Richardson, S.D., et al.: Environ. Sci. Technol, 37, 3782-3793 (2003);<br></p>

<p>Applications 2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, F., et al.: Bull. Enviro. Contamin. Toxicol., 89, 316 (2012); Zhong, W., et al.: J. Hazard. Mat., 217, 286 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications Aniline Hydrochloride is used in the making of new azo pyridone dyes for polyester fabrics and in the microwave-assisted preparation of arylazoaminopyrazoles as disperse dyes for textile printing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khattab, T. A., et al.: Z. Anorg. Allg. Chem., 642, 766 (2016); Al-Etaibi, A., et al.: Eur. J. Chem., 5, 321 (2014)<br></p>

<p>Applications Trigonelline (chloride) is an alkaloid found in plants and coffee. Trigonelline is a product of niacin metabolism that is excreted in urine.<br></p>

<p>Applications 1-Bromo-9-(tert-butyldimethylsilyloxy)nonane is used in the preparation of Fulvestrant (F862500) intermediate.<br>References Liu, W., et al.: Faming Zhuanli Shenqing (2014), CN 103965280 A 20140806<br></p>

<p>Applications 4-Bromo-2,2-diphenylbutyric Acid (cas# 37742-98-6) is a compound useful in organic synthesis.<br></p>

<p>Applications o-tert-Butyl-α-chlorotoluene is a useful research reagent for the competitive chloromethylation of alkylbenzenes.<br>References Takezawa, T., et al.: Nippon Kagaku Kaishi 6, 1047 (1989); Hu, Y. L., et al.: J. Chil. Chem. Soc., 55, 97 92 (2010); Pinnell, R. P., et al.: Tetrahedron Lett., 25, 3511 (1984)<br></p>

<p>Applications 4-Aminomethyl Benzamidine Dihydrochloride is a small molecule CXCR4 antagonist.<br>References Zhan, Weiqiang, et al.: J. of Med. Chem., 50(23), 5655-5664 (2007)<br></p>

<p>Applications 3-(2,2,2-trifluoroethoxy)prop-1-yne (cas# 1481-06-7) is a useful research chemical.<br></p>

<p>Applications 3-Iodobenzoic Acid (cas# 618-51-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 2-Chloropropionate is used to elucidate structural and functional properties of the LRRK2 protein ATP-binding pocket, which plays a major role in the late-onset Parkinson Disease.<br>References Liu, Z. et al.: J. Biol. Chem., 289, 32937 (2014);<br></p>

<p>Applications 6-Bromo-2-napthoic Acid is used in the preparation of Adapalene, a synthetic aromatic retinoid with specificity for RARβ and RARγ receptors.<br>References Milanese, A. et al.: Bioorg, Chem., 39, 151 (2011);<br></p>

<p>Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.<br>References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)<br></p>

<p>Applications 2-Iodoacetamide is an alkylating agent commonly used in the alkylation of proteins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Woods, A.G.,et. al.: Biochem. Bioph. Res. Co., 419, 305 (2012); Samgina, T.Y., et. al.: J. Am. Soc. Mass Spec., 22, 2246 (2011)<br></p>

<p>Stability Moisture Sensitive<br>Applications Methyltin Trichloride is used in the synthesis of metallasilesesquiloxanes used for their important application to silica surfaces. Also used in the preparation of organotin(IV) complexes showing antibacterial activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feher, F. et al.: J. Am. Chem. Soc., 114, 3859 (1992); Salam, M., Heteroatom Chem., 24, 43 (2013);<br></p>

<p>Impurity Fluorouracil EP Impurity E<br>Applications Used for the experimental and clinical treatment of neoplastic and viral diseases. Fluorouracil EP Impurity E.<br>References Yu, H., et al.: J. Biol. Chem., 268, 15935 (1993), Staleva, L., et al.: Mutat. Res., 370, 81(1996), Harris, V., et al.: J. Mol. Biol., 326, 1389 (2003)<br></p>

<p>Applications 1-Bromobenzene, is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);<br></p>

<p>Applications An intermediate in the synthesis of Erlotinib.<br></p>

<p>Applications Ethylenebis(tetrabromophthalimide) is an additive fire retardant that is added to a polymer mixture to produce a blend. Ethylenebis(tetrabromophthalimide) is used in high impact polystyrene (HIPS), polyethylene, polypropylene, thermoplastic polyesters, polyamide, ethylene propylene-diene terpolymers (EPDM rubbers) and other synthetic rubbers, polycarbonate, ethylene copolymers, ionomer resins, epoxies, and textile treatments.<br>References Clausen, E., et al.: Anal. Chem., 327, 297 (1987);<br></p>

<p>Applications 2-Chloro-1,3,2-dioxaphospholane-2-oxide is used in the synthesis of α-naphthylphosphorylcholine as a method to detect phospholipase C activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Durban, M. et al.: Eur. J. Lipid. Sci. Tech., 105, 633 (2003);<br></p>

<p>Applications 2-[(4-fluorobenzyl)amino]ethanol (cas# 22116-33-2) is a useful research chemical.<br></p>

<p>Applications Furoyl Chloride is used in the preparation of novel dibenzothiepins that show antibiofilm activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stecoza, C. et al.: Curr. Org. Chem., 17, 113 (2013);<br></p>

<p>Applications 2-chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine (cas# 101862-47-9) is a useful research chemical.<br></p>

<p>Applications 4-Azido-2,3,5,6-tetrafluorobenzamide (cas# 122616-98-2) is a compound useful in organic synthesis.<br></p>

<p>Applications A chemical additive to control bacterial contamination in ethanol fermentation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vaisanen, O., et al.: J. Ind. Microbio., 4, 419 (1989), Costerton, J., et al.: J. Bacteriol., 176, 2137 (1994), Pirttijarvi, T., et al.: J. Appl. Bacteriol., 81, 445 (1996),<br></p>

<p>Applications 4-Chlorophenylamine is an organic chemical reagent and precursor in the synthesis of various drugs and dyestuffs. It is a building block and a degredation product of Chlorhexidine (C335045), an antiseptic as well as azo dyes and pigments in printing and textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leucea, D. et al.: Ind. Text., 61, 304 (2010); Below, H. et al.: Microchim. Acta 146, 129 (2004);<br></p>

<p>Applications 2-Iodoheptafluoropropane is a useful synthetic intermediate. It is a reagent used to prepare a-trifluoromethyl carbonyl compounds and novel amino acids.<br>References Pham, P., et al.: Angewandte Chemie, 50, 6119 (2011); McNabb, S., et al.: Org. Lett., 6, 1911 (2004)<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>

<p>Applications Axitinib Iodo Tetrahydropyran is an analog of Axitinib (A794650). Axitinib (A794650) is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003);Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorodecyltriethoxysilane is used in making thin film transistors, polyethersulfone membranes, and a superwettable Janus membrane.<br>References Zhu, Zhigao, et al.: J. of Membrane Sci., 563, 602-609 (2018); Khan, Aftab A., et al.: Separation and Purification Tech., 210, 20-28 (2019); Shih, Andy, et al.: MRS Adv., 3(33), 1877-1882 (2018)<br></p>

<p>Applications 2,2,2-trichloroethanol (TCE) is an active metabolite of Trichloroacetaldehyde monohydrate [chloral hydrate (CH)] (T774055), a sedative/hypnotic that increases cerebral blood flow (CBF).<br>References Parelkar, N., et al.: J. Pharma. Exper. Ther., 332, 803 (2010); Merdink, J., et al.: Toxicol, 245, 130 (2008)<br></p>

<p>Applications Butylamine Hydrochloride is a miscellaneous reagent used in the synthesis of benzamides for the synthesis of various drugs and polymers.<br>References Bantreil, X. et al.: Eur. J. Org. Chem., 2015, 416 (2015);<br></p>

<p>Stability Volatile<br>Applications Ethyl trifluoromethanesulfonate (cas# 425-75-2) is a useful reagent for the enantioselective preparation of γ-fluoroamines.<br>References Roagna, G., et al.: J. Am. Chem. Soc., 142, 14045 (2020)<br></p>

<p>Stability Moisture sensitive<br>Applications Diisopropyl Phosphorochloridate is a phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents.<br>References Zhang, H., et al.: Bioorganic Med. Chem. Lett., 22, 3598 (2012).<br></p>

<p>Applications 2,6-Difluorobenzoylacetonitrile is used in the synthesis of thienodiazepinones which can have poor central nervous system depressant activity.<br>References Binder, D., et al.: Arch. Pharm., 313, 587 (1980)<br></p>

<p>Impurity Adapalene USP Related Compound A<br>Applications Methyl 6-Bromo-2-napthoate (Adapalene USP Related Compound A) is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.<br>References Milanese, A. et al.: Bioorg. Chem., 9, 151 (2011);<br></p>

<p>Impurity Lamotrigine USP Related Compound B/ Lamotrigine EP Impurity E<br>Applications 2,3-Dichlorobenzoic Acid (Lamotrigine USP Related Compound B) is the key intermediate for antiepileptic drug Lamotrigine (L173250) and other pharmaceuticals for the treatment of central nervous system (CNS) disorders and disease.<br>References Liao Q., et al.: JingXi. Huagong., 36, 18 (2006); Qadeer, G., et al.: J. Brazilian. Chem. Soc., 18, 1176 (2007); Pellon, R.F., et al.: Syn. Commun., 37, 1853 (2007); Wang, J.F., et al.: Thermochimica. Acta., 512, 118 (2011);<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorooctyl-1-thiol acts as a reagent in the preparation, structure, and antitumor activity of dinuclear arene ruthenium thiolato complexes with fluorous side-chains. Reagent in the preparation of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders.<br>References Stibal, D., et al.: Inorganica Chimica Acta, 444, 51 (2016); Durand, G., et al.: Bioorg. Med. Chem. Lett., 13, 859 (2003)<br></p>

<p>Applications CHLOROFLUOROACETAMIDE (cas# 431-09-4) is a useful research chemical.<br></p>

<p>Applications Triethylamine Trihydrofluoride is used in the synthesis of modified siRNA’s in vivo used to inhibit hepatitis B replication (1). Used in RNA synthesis in the removal of t-butyldimethylsilyl protection (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Marimani M. et al.: Bioorg Med Chem. 2013 Oct 15;21(20):6145-55. 2. Westman, E. et al.: Nucleic Acids Res. 1994 Jun 25;22(12):2430-1<br></p>

<p>Stability Air Sensitive<br>Applications 4,5-Dichloro-2-octyl-3(2H)-isothiazolone (cas# 64359-81-5) is a useful research chemical.<br></p>

<p>Applications 4-Bromo-2-chlorophenol<br></p>

<p>Applications Hydrazine Dihydrochloride (cas# 5341-61-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol<br></p>

<p>Applications 4-(2-Chlorophenyl)-cyclohexanone is used in the synthetic preparation of cyclohexyl pyridylpiperazines as Δ8-Δ7 sterol isomerase ligands with antiproliferative activity.<br>References Berardi, F., et al.: J. Med. Chem., 51, 7523 (2008)<br></p>

<p>Applications 1H,1H,2H-Perfluoro-1-Octene (cas# 25291-17-2) is a useful research chemical.<br></p>

<p>Applications An intermediate for the preparation of Citalopram.<br></p>

<p>Applications Benzetimide Hydrochloride has anticholinergic properties and can block pilocarpine-induced lacrimation or salivation at submydriatic dose levels.<br>References Paul, A.J., et al.: Psychopharmacologia, 11, 231 (1967)<br></p>

<p>Applications (3-Azidopropyl)triphenylphosphonium Bromide (cas# 127611-39-6) is a compound useful in organic synthesis.<br></p>

<p>Applications (S)-4,4-Difluoro-N-(3-oxo-1-phenylpropyl)cyclohexanecarboxamide acts as a reagent in the synthesis of CCR5 antagonists which are used in HIV therapy and may also be relevant for the treatment of graft-vs.-host disease and Staphylococcus aureus infection.<br>References Asano, S., et al.: ACS Med. Chem. , 5, 133 (2014)<br></p>

<p>Impurity Bupropion 2-Bromo Impurity (Related Compound G)<br>Applications 3’-Chloro-2-bromopropiophenone (cas# 34911-51-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.<br>References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).<br></p>

<p>Applications 4-Fluoro-3-nitrobenzotrifluoride is an intermeidate used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids and [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Higashi, T., et al.: Anal. Sci., 18, 1301 (2002); Caci, E., et al.: Am. J. Physiol. Lung Cellular and Molecular Physiology, 285, L180 (2003)<br></p>

<p>Impurity Adamantane Impurity 3<br>Applications 1-Ethyl-3-bromoadamantane have been used in the synthesis of 1-adamantyloxyalkanols. Adamantane Impurity 3<br>References Reznikov, A.N., et al.: Russ. J. Org. Chem., 46, 1741 (2010); Henkel, J.G., et al.: J. Med. Chem., 25, 51 (1982);<br></p>

<p>Applications Bromochloroacetamide is a haloacetemide byproduct of nitrogenous disinfection agents at water purification plants in European and Asian countries.<br>References Kosaka, K. et al.: Water Res., 106, 470 (2016);<br></p>

<p>Applications This compound is used in the synthesis of Diclazuril (D436200) and diclazuril derivatives.<br></p>