Investigação da doença de Alzheimer

Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment …

BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and …

AChE-IN-27 is a small molecule used for high-throughput assays.

Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used …

δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead …

Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and …

SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the …

Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine …

SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist

Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in …

Tacrine (CS 12602) is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved …

Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL.

GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate

Perivine (Perivin) may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be …

Fasoracetam is a modulator of GABA receptor potentially for the treatment of attention deficit hyperactivity …