Bioquímicos e reagentes

<p>CD107b antibody (FITC) was raised in rat using glycoproteins purified from BALB/c mouse embryo 3T3 cell line as the immunogen.</p>

<p>Ly2444296, also known as FP3FBZ, is an experimental pharmaceutical compound, specifically a small-molecule antagonist designed to target a particular receptor system in the central nervous system. It is synthesized through a complex series of chemical reactions, leveraging advanced organic synthesis techniques. The primary mode of action for Ly2444296 is the selective inhibition of the norepinephrine transporter (NET), which results in increased levels of norepinephrine in the synaptic cleft. This modulation of neurotransmitter dynamics can have significant effects on mood and stress responses.</p>

<p>7-((Benzo[D]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol is a synthetic investigational compound, which is typically synthesized in a laboratory setting through a series of chemical reactions involving quinoline derivatives and other complex organic molecules. This compound is designed to target and inhibit specific molecular pathways involved in cancer cell proliferation and survival. Its mode of action is believed to involve the disruption of signaling pathways critical to tumor growth, potentially through interaction with specific kinases or receptor sites on the cancer cells.</p>

<p>Altretamine hydrochloride is a chemotherapy drug that is metabolized by methylating enzymes, which are primarily located in the liver. It inhibits tumor growth by inhibiting the function of DNA polymerase and DNA topoisomerase I, which are enzymes involved in DNA replication and repair. Altretamine also has anti-cancer activity against respiratory tract tumors. It is not active against tumors that have no oxygen requirements (e.g., breast cancer). Altretamine is toxic to cells when it binds to methyl groups because it prevents their use for other cellular processes. The effects of altretamine on the environment are unknown but may be significant given its high toxicity to aquatic organisms.</p>

<p>ML 339 is a novel immunosuppressant drug that has been shown to be effective in the treatment of autoimmune diseases. It is a selective, reversible inhibitor of phosphodiesterase 4 (PDE4) and prevents the breakdown of cyclic adenosine monophosphate (cAMP), a signaling molecule that is important for immune responses. In animal models, ML 339 has been shown to suppress immune responses and prevent the development of autoimmune disease. It has also been shown to preserve transplanted organs from rejection.</p>

<p>Gamma globulin antibody is a type of antibody that is used in the field of Life Sciences. It is a chemokine that plays a crucial role in immune response and inflammation. This antibody is commonly used in research and diagnostic applications, as well as in therapeutic treatments. Gamma globulin antibodies can be either monoclonal or polyclonal, depending on their origin and specificity.</p>

<p>CD22 antibody (FITC) was raised in rat using CD22 as the immunogen.</p>

<p>Please enquire for more information about 4-[4-(2-Naphthalenylsulfonyl)-1-piperazinyl]-2-(2-thienyl)quinazoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Carlina oxide is a natural antibacterial compound that has been shown to inhibit the growth of C. glabrata and other bacteria. It is an antioxidant compound with strong antioxidative activity, which has been demonstrated by its ability to protect cells from damage induced by hydrogen peroxide. Carlina oxide also shows potent cytotoxicity against human cancer cells and has been shown to be effective in animal models for the treatment of infections caused by E. coli and F. faecalis strains. This compound has not yet been synthesized but can be extracted from the leaves of carline thistle (Carlina vulgaris).</p>

<p>BC1618 is a peptide that activates the GABA(A) receptor. It has been shown to be a high-potency activator of the GABA(A) receptor, with an EC50 of 2.5 nM in recombinant cell lines. BC1618 has also been shown to inhibit ligand-gated ion channels and produce long-lasting changes in cell membrane potentials. In addition, BC1618 is a potent inhibitor of the voltage-dependent calcium channel (VDCC) current with an IC50 of 100 nM.</p>

<p>Complement C3 is a protein that inhibits the pathogenic mechanisms of bacteria and viruses. It is present in maternal blood and can be used to diagnose diseases such as bowel disease or injury. Complement C3 has been shown to activate the immune system by binding to toll-like receptors on macrophages, which are cells that engulf foreign objects, including bacteria and viruses. The activation of toll-like receptors leads to the production of cytokines, which are proteins involved in cell signaling. Complement C3 also plays a role in iron homeostasis by preventing the insertion of iron into ferritin, an iron storage protein found in most cells.</p>

<p>Vu 590 is a histone deacetylase inhibitor that has been shown to have cardioprotective effects. Vu590 binds to the HAT domain of HDAC and prevents the removal of acetyl groups from histones, which causes an increase in gene expression. It also inhibits the activity of ionophores, which are molecules that transport ions across membranes. Vu 590 binds to ionophore channels and blocks their opening, preventing the flow of ions. This drug also has a number of other effects on dopamine and serotonin release, as well as coexpression with adenosine receptors.</p>

<p>KLRG1 antibody (PE) was raised in hamster using activated NK (A-LAK) cells from B6 mice as the immunogen.</p>

<p>Inhibits dopamine, serotonin and adrenergic receptors</p>

<p>Teludipine hydrochloride is a drug that has been shown to inhibit the growth of cancer cells in vitro and in vivo. Teludipine hydrochloride inhibits cell proliferation by binding to the extracellular domain of the proprotein convertase subtilisin/kexin type 9 (PCSK9) and preventing it from binding to its receptor. Teludipine hydrochloride also inhibits PCSK9-induced cancer cell death. It has been shown that teludipine hydrochloride can be used as an anti-cancer agent, which may be due to its ability to inhibit PCSK9-induced cellular activation and signal transduction. This drug also binds to disulfide bonds on proteins, which may lead to inhibition of the reaction solution.</p>

<p>Please enquire for more information about Phosphatidylinositol sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-681217 is a peptide that stimulates the α2A adrenergic receptor and has been shown to activate ion channels. It can be used as a research tool in the study of pharmacology, protein interactions, and receptor function. L-681217 is also an antibody ligand, which binds to receptors on cells of the immune system. The antibody then triggers a response from the cell.</p>

<p>MS37452 is an antimicrobial peptide, which is a type of biomolecule sourced from natural or synthetic origins. These peptides are known for their ability to interact with bacterial cell membranes through electrostatic interactions and hydrophobic insertions. This mode of action leads to the disruption of bacterial cell integrity, resulting in cell lysis and death.</p>

<p>M2 ion channel blockers are a class of antiviral drugs that block the M2 ion channel. They are used for the treatment and prevention of influenza, HIV, and other viruses. M2 ion channel blockers have been shown to inhibit viral growth and replication in vitro by blocking the proton conductance through the M2-pore. This proton conductance is required for the synthesis of new virus particles. The potency of M2 ion channel blockers is influenced by drug interactions with other medicines, such as protease inhibitors used to treat HIV. They can also affect virus strain selection, as they may select for strains resistant to these agents, which leads to more difficult treatment and more severe complications from infection. These agents have not been shown to be effective against pandemic influenza due to their sensitivity limitations in detecting low levels of influenza A type H1N1 virus when present in a patient’s respiratory tract.</p>

<p>A 33 is a polymeric matrix that is programmable and can be used to create an osmotic device. It consists of a fibre with a cyclic oligomeric matrix (COM) that is hydrophilic on one side and hydrophobic on the other. The two surfaces are connected by a membrane. The COM is designed to change the pH of the solution on either side, depending on the desired effect. For example, if it is desirable for the system to maintain a basic pH, then the hydrophobic side should be placed in contact with an acidic solution, while the hydrophilic side should be placed in contact with a basic solution. This produces an osmotic system that has different properties at different pH levels. A 33 has been tested as a treatment for systemic sclerosis and has shown promising results in animal models.</p>

<p>Heparanase 1 (HPA1) is a protein that in humans is encoded by the HPA1 gene. The protein encoded by this gene hydrolyzes heparan sulfate, which is a negatively charged glycosaminoglycan found in extracellular matrices. It has been shown to be an important regulator of angiogenesis, and it also plays a role in tumor cell migration. InSight Polyclonal Rabbit Anti-Human Heparanase 1 antibody recognizes human heparanase 1 with high affinity and specificity. This antibody will allow you to study the expression and function of this protein in various cell types, as well as its involvement in specific biological processes.</p>

<p>Tert-Butyl 3-benzyl-4-{4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazole-1-carbonyl}piperazine-1-carboxylate is a specialized chemical compound, primarily utilized in the field of medicinal chemistry. This compound is synthetically derived, often produced through multi-step organic synthesis processes that incorporate click chemistry techniques, leading to the formation of 1,2,3-triazole rings.</p>

<p>p-Nitroblebbistatin is a photostable small-molecule inhibitor, which is derived from the original compound blebbistatin. It acts specifically on non-muscle myosin II ATPase, inhibiting its activity without affecting other myosin isoforms or closely related ATPases.</p>

<p>Inhibitor of PI3K kinases</p>

<p>Rasfonin is a natural product that was found in an extract of the plant Etoac. It has been shown to inhibit the growth of pancreatic cancer cells and have anticancer activity. Rasfonin is structurally similar to the anticancer drug temozolomide, but it does not have any known toxicity. Rasfonin binds to DNA and inhibits transcriptional activation by the nuclear factor-kappa B (NF-κB) pathway. It also induces autophagy, which is important for maintaining cellular homeostasis, preventing tumor formation, and inducing apoptosis. This compound has been shown to inhibit proliferation of normal as well as cancerous cells in vitro and in vivo.</p>

<p>CD107b antibody was raised in rat using glycoproteins purified from BALB/c mouse embryo 3T3 cell line as the immunogen.</p>

<p>CD45 antibody (biotin) was raised in Rat using CD45/LCA as the immunogen.</p>

<p>CD8a antibody (PE) was raised in Mouse using the alpha chainc of chicken CD8 as the immunogen.</p>

<p>3-Morpholino-1-phenylpropan-1-one is a potent inhibitor of hepg2 cells (human hepatoma) and microglia cells (brain cells). 3-Morpholino-1-phenylpropan-1-one binds to hepg2 and microglia cells and inhibits the production of proinflammatory cytokines, such as IL-6, TNFα, and IL-8. It has been shown that 3MOPP can inhibit the synthesis of phenylpropanoids in dasycarpus plants. This inhibition may be due to its binding to caffeic acid or other glycosidic functional groups.</p>

<p>CD8a antibody (biotin) was raised in Mouse using the alpha chainc of chicken CD8 as the immunogen.</p>

<p>Auristatin F TFA salt is a potent antitumor agent that can be used for the treatment of solid tumours. It inhibits the growth of cancer cells by binding to epidermal growth factor (EGF) receptors and blocking the action of EGF. Auristatin F TFA salt has been shown to induce apoptosis in prostate cancer cells and can also act as a potential biomarker for tumour response. The drug is not toxic to healthy cells, but it is rapidly eliminated from the body due to its short half-life. Auristatin F TFA salt has been shown to have pharmacokinetic properties that are similar in mice, rats, and humans. This drug also binds monoclonal antibodies against EGFR, which may serve as an alternative treatment for cancer patients who develop resistance to temozolomide.</p>

<p>CD20 antibody (PE-CY7) was raised in mouse using human CD20 as the immunogen.</p>

<p>N-[2-[(2-Hydroxyethyl)amino]ethyl]-(3beta)-cholest-5-ene-3-carboxamide is a potent kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting kinases, which are enzymes that play a crucial role in cancer cell growth and survival. This compound has been found to induce apoptosis (programmed cell death) in tumor cells, making it a potential anticancer agent. N-[2-[(2-Hydroxyethyl)amino]ethyl]-(3beta)-cholest-5-ene-3-carboxamide has also been shown to be effective against linezolid-resistant strains of bacteria and may serve as an analog for developing new antibiotics. In Chinese hamster ovary cells, this compound has demonstrated potent inhibition of protein kinase CK1δ activity and exhibited cytotoxicity against human cancer cell lines. Overall, N-[2-[(2-Hydroxyethyl)amino</p>

<p>Please enquire for more information about 2Abz-Acp-Ala-Phe(4-NO2)-Leu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hydroxyzine acetic acid is an inhibitor of human kinases, which are proteins involved in cell signaling pathways. It is an analog of tolvaptan, a drug used to treat tumors and cancer cells. Hydroxyzine acetic acid has been shown to induce apoptosis, or programmed cell death, in various types of cancer cells. This compound may have potential as an anticancer agent due to its ability to inhibit the activity of Chinese hamster ovary (CHO) kinases. Additionally, it has been found in urine samples from patients with cancer, suggesting that it may be a useful biomarker for cancer diagnosis and treatment monitoring.</p>

<p>PI 103 hydrochloride is a pharmacological compound, specifically a dual inhibitor, which is synthetically derived. It acts by inhibiting both the phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) pathways. This compound disrupts signaling pathways critical for cell growth and survival, making it a valuable tool in cancer research. By targeting these pathways, PI 103 hydrochloride is used to investigate cellular processes and mechanisms underlying tumor growth and proliferation. Researchers employ this compound to study the effects of pathway inhibition on cancer cells, potentially leading to the development of novel therapeutic strategies. This makes PI 103 hydrochloride a significant component in the exploration of targeted cancer therapies and advanced studies in cellular biology.</p>

<p>The Plasminogen antibody is a growth factor that plays a crucial role in various biological processes. It contains acid residues that enable it to bind to fibrinogen and exert its proteolytic activity. This Polyclonal Antibody can specifically recognize and bind to the Plasminogen antigen, leading to the formation of antigen-antibody complexes. These complexes have been shown to have various biological effects, including the regulation of hepatocyte growth and the modulation of microvessel density.</p>

<p>Cefprozil-d4 is an inhibitor of protein kinases, which are enzymes that regulate various cellular processes including cell growth and division. It has been shown to have anticancer properties in vitro and in vivo, inhibiting the growth of tumor cells by inducing apoptosis. Cefprozil-d4 is an analog of cefprozil, a cephalosporin antibiotic used to treat bacterial infections. In addition to its anticancer effects, it has been found to inhibit elastin degradation in urine samples from patients with bladder cancer. This suggests that cefprozil-d4 may have potential as a therapeutic agent for the treatment of cancer and other diseases involving abnormal protein kinase activity.</p>

<p>Please enquire for more information about Sec-butyl 2-bromoacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>GSK983 is a drug that inhibits papilloma virus by acting as an analog. It is thought to work by inhibiting the synthesis of uridine, which is needed for viral DNA replication. GSK983 has been studied in various model organisms and cell cultures to determine its mechanism of action. This drug has shown efficacy against cancers and infectious diseases, such as herpes simplex virus. GSK983 binds to the cellular target with high affinity and inhibits viral replication in vitro and in vivo by targeting the viral life cycle at the stage of DNA synthesis.</p>

<p>Please enquire for more information about YCN47284 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>BTUM is a medicinal compound that acts as an analog of human kinases. It has been shown to have potent anticancer properties, inhibiting the growth and proliferation of cancer cells by inducing apoptosis and disrupting the cell cycle. BTUM works by binding to specific proteins in cancer cells, which are involved in the regulation of cell growth and division. This inhibitor prevents these proteins from functioning properly, leading to the suppression of tumor growth. BTUM has been extensively studied in Chinese medicine, where it has been used for its anti-cancer properties for many years. With its ability to target cancer cells specifically, BTUM is a promising candidate for the development of new cancer therapies.</p>

<p>CD19 antibody (PE-CY5.5) was raised in mouse using human CD19 as the immunogen.</p>

<p>Apcin-A is an anticancer analog that functions as a kinase inhibitor. It has been shown to inhibit the activity of various kinases, including those involved in cancer cell growth and proliferation. Apcin-A is derived from human urine and has demonstrated potent anticancer activity against a range of tumors. This protein inhibitor induces apoptosis in cancer cells, leading to their death. Apcin-A has also been found to be effective against Chinese hamster ovary cells and elastin-induced cell proliferation. With its ability to target specific kinases, Apcin-A shows great potential as a therapeutic agent for cancer treatment.</p>

<p>CD106 antibody (FITC) was raised in rat using murine CD106/VCAM-1 as the immunogen.</p>

<p>CP-226269 is a synthetic glucocorticoid, which is a type of steroid hormone. This compound is derived from chemical synthesis, originating from laboratories dedicated to the development of advanced biomolecules for research. Its mode of action involves binding to glucocorticoid receptors, which are part of the nuclear receptor superfamily. Once bound, it modulates the expression of target genes that play pivotal roles in inflammation, immune response, and metabolic processes.</p>

<p>TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. The TentaGel S base resins are available with several different derivative choices. The typical capacity range for our TentaGel base resins is 0.2-0.3 meq/g.<br>Application: (90 µm)<br>Substitution Functional Group:-CH2-CH2-SH</p>

<p>Ribalinium chloride is an anticancer drug that works by inhibiting the activity of protein kinases, which are enzymes involved in cell division and growth. It has been shown to be effective against a variety of cancer types, including leukemia and tumors. Ribalinium chloride induces apoptosis, or programmed cell death, in cancer cells by blocking the cell cycle and preventing them from dividing further. It is derived from Chinese medicinal plants and has been used traditionally for its anti-tumor properties. Ribalinium chloride is excreted mainly through urine and acts as a potent inhibitor of protein kinase activity. This makes it a promising candidate for the development of new cancer treatments that target specific signaling pathways involved in tumor growth and progression.</p>

<p>CD5 antibody (PE) was raised in rat using CD5/Lyt-1 as the immunogen.</p>

<p>Please enquire for more information about 1,3-Dilignoceroyl glycerol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>CD8a antibody (FITC) was raised in rat using mouse thymus or spleen as the immunogen.</p>

<p>Grk2I is a selective inhibitor, which is a synthetic compound designed to target G protein-coupled receptor kinase 2 (GRK2). This compound is developed through intricate chemical synthesis, enabling precise modulation of GRK2 activity. Its mode of action involves the competitive inhibition of GRK2, thereby preventing it from phosphorylating target receptors. This disruption of receptor phosphorylation subsequently alters downstream signaling pathways, which can be crucial in various physiological and pathological processes.</p>

<p>H-Arg-Arg-Arg-Arg-OH is a peptide that belongs to the group of activators. It has been shown to activate the immune system by stimulating antibody production, and is used as a research tool for studying ion channels, life science, cell biology, and pharmacology. H-Arg-Arg-Arg-Arg-OH has been shown to act as an inhibitor of protein interactions in various systems. The receptor for this peptide is unknown.</p>

<p>CD19 antibody (PE-CY7) was raised in rat using murine CD19-expressing K562 human erythroleukemia cells as the immunogen.</p>

<p>CD19 antibody (PE) was raised in mouse using human CD19 as the immunogen.</p>

<p>CD24 antibody (Spectral Red) was raised in rat using murine heat stable antigen as the immunogen.</p>

<p>CD45RB antibody (FITC) was raised in rat using cloned mouse Th2 cell lines as the immunogen.</p>

<p>Inhibits mutated EGFR with exon 20 insertion; anti-cancer agent</p>

<p>Cpp is a peptide with a molecular weight of 8.7 kDa and a length of 6 amino acids. It was originally isolated from the venom of the Brazilian spider Phoneutria nigriventer, but has also been found in other organisms such as scorpions, bees, and sea anemones. Cpp is an activator of voltage-gated sodium ion channels. It binds to the extracellular domain of the sodium channel and opens it by changing its conformation. This binding prevents fast inactivation of sodium channels that are activated by depolarization. This inhibition leads to an increase in action potential duration and amplitude, which may be one mechanism underlying Cpp's neurotoxic effects.</p>

<p>Piragliatin is a potent inducer of glucose-dependent insulinotropic peptide (GIP) receptor. It has been shown to have a hypoglycemic effect in tissue culture and to reduce hepatic steatosis in mice. Piragliatin also potentiates the effect of glp-1r agonists, which are used for the treatment of type 2 diabetes mellitus, by increasing glucose uptake into fat cells and enhancing insulin secretion.</p>

<p>Mevociclib is a potent inhibitor of the Bcl-2 protein, which is considered to be a key regulator of cell death. It binds to the kinase domain of the Bcl-2 protein, inhibiting its function and promoting apoptosis. Mevociclib has shown potent antitumor activity in clinical studies against patients with high-risk diseases such as cancer and cell culture experiments against carcinoma cells. This drug also inhibits transcriptional regulation by suppressing specific genes that inhibit apoptosis pathways.</p>

<p>N,N-Bis-desethyl, N-methyl entacapone is a potent inhibitor of cancer cell growth and has been shown to have anticancer properties. It works by inhibiting the activity of certain proteins that are involved in tumor growth and survival. This inhibitor has been shown to be effective against various types of cancer cells, including those found in human urine and Chinese hamster ovary cells. It has also been found to induce apoptosis, or programmed cell death, in cancer cells. N,N-Bis-desethyl, N-methyl entacapone is an analog of elastase inhibitors and has been shown to inhibit the activity of kinases, which are enzymes that play a key role in cellular signaling pathways. This inhibitor may hold promise for the development of new cancer therapies.</p>

<p>GSK598809 is a non-selective, high-affinity, amide-type dopamine D2 receptor antagonist that is currently in phase II clinical trials for the treatment of dystonia. This drug binds to the D2 receptor with high affinity and specificity and has shown efficacy in animal models of Parkinson's disease. GSK598809 has been shown to have low expression in humans, as well as no adverse effects on human red blood cells. It also has a low potential for abuse or dependence due to its lack of activity at other neurotransmitter receptors.</p>

<p>VRK-IN-1 is an antibody that binds to the peptide sequence VRKK. This antibody has been used as a research tool for the study of protein interactions, ion channels, and ligand activation. VRK-IN-1 can be used in the lab to inhibit receptor or ligand binding by competing with the target protein for binding. VRK-IN-1 is purified from rabbit serum and has a purity of &gt;98%.</p>

<p>Jaspamycin is an antitumor antibiotic, which is a natural product isolated from the bacterium *Streptomyces hygroscopicus*. Its mode of action involves disrupting RNA synthesis by inhibiting nucleic acid chain elongation, thereby impeding cell proliferation and leading to cell death in rapidly dividing cancer cells. This mechanism makes Jaspamycin particularly effective as a chemotherapeutic agent.</p>

<p>LEAP-2 (38 - 77) (Human) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-LLEVPEGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>RO8191 is a small molecule that has been shown to inhibit replication of hepatitis B virus (HBV) in vitro and in vivo. RO8191 has also been shown to inhibit replication of human papillomavirus (HPV) and cervical cancer cells. In cellular systems, RO8191 inhibits the activity of cellular polymerase chain reaction (PCR) replicons, which are used as a model for HBV and HPV replication. The compound also inhibits the activity of replicons derived from human immunodeficiency virus type 1 (HIV-1). In vivo, RO8191 inhibited viral load in mice infected with HBV.<br>Mesenchymal stromal cells (MSCs) have been shown to express high levels of RO8191's target enzyme, poly(ADP-ribose) polymerase 1 (PARP-1), suggesting that MSCs may be an effective delivery vehicle for this drug. This drug has not yet been evaluated for</p>

<p>CD3 antibody (Allophycocyanin-CY7) was raised in mouse using the epsilon chain of CD3/T-cell antigen receptor complex as the immunogen.</p>

<p>CD19 antibody (PE-Texas Red) was raised in mouse using human CD19 as the immunogen.</p>

<p>Dxd is a type of Antibody-Drug Conjugate (ADC), which is a sophisticated therapeutic agent arising from bioconjugate chemistry. It incorporates a monoclonal antibody that specifically targets cancer cell antigens, linked to a cytotoxic payload designed to induce cell death. The mechanism of action involves the highly selective binding of the ADC to a cancer-specific antigen, followed by internalization, and subsequent release of the cytotoxic agent within the cell. This targeted approach allows for the preferential destruction of cancer cells while minimizing damage to healthy tissues.</p>

<p>Estradiol 3-sulfamate is a synthetic estrogen analogue, which is derived from the natural estrogen hormone, estradiol. Its mode of action involves the inhibition of steroid sulfatase, an enzyme responsible for converting sulfated steroid precursors into active estrogens. This inhibition reduces estrogen levels and influences the hormonal regulation pathways within the body.</p>

<p>CD44 antibody (FITC) was raised in mouse using chicken CD44 as the immunogen.</p>

<p>H-VMGPRTLIL-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>H-GNDIAFHFNPR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Simvastatin Na is the salt form of Simvastatin. It acts as HMG-CoA reductase inhibitor and suppresses TNF-mediated NF-kappaB activation.</p>

<p>Peptide H-SAGGE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>ANQ 11125 is a linker that is used to connect therapeutic molecules to blood-based transport vectors. This linker has been shown to be efficient in conjugating the therapeutic molecules to cells of all types, including those from humans and animals.</p>

<p>YUKA1 is a protein that in humans is encoded by the YUK1 gene. It regulates cellular growth, differentiation and migration. YUKA1 has been shown to be overexpressed in breast cancer tissues, and has been shown to promote angiogenesis and tumor growth. This protein also interacts with the epidermal growth factor receptor (EGFR), which is a cell surface receptor tyrosine kinase involved in regulating cell proliferation, survival and motility. Yuka1 has been shown to bind histone H3 lysine 36 (H3K36) at specific regions of DNA called CpG islands. These regions are found near genes that are turned on or off by methylation, which can lead to changes in gene expression levels.</p>

<p>N-[[4-(1-Methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine is a research tool that activates the Ligand and Receptor. It has been developed as a ligand for GPCR receptors, such as the cannabinoid receptor 1 (CB1). This drug also functions as an inhibitor of ion channels, including sodium channels and potassium channels. NMPPIPA also inhibits protein synthesis by binding to ribosomes.</p>

<p>8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a potent analog that has been extensively studied for its medicinal properties. It has been shown to be an effective inhibitor of protein kinase and cell cycle regulators, which are important targets for cancer therapy. This compound induces apoptosis in cancer cells and has shown promising results as an anticancer agent. Additionally, 8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen has been found in human urine and may have potential as a tumor marker or diagnostic tool. Its unique structure and potent activity make it a valuable addition to the field of cancer research.</p>

<p>Peptide H-ATNVAHWTTPSLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EELTVSEFL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Agomelatine (L(+)-tartaric acid) is a synthetic antidepressant, which is derived from chemical synthesis. It acts primarily by serving as an agonist at melatonin MT1 and MT2 receptors and as an antagonist at 5-HT2C serotonin receptors. This dual mechanism of action is particularly significant as it helps regulate sleep-wake cycles and mood by re-establishing normal circadian rhythms.</p>

<p>CD23 antibody (PE-CY7) was raised in rat using CD23 low affinity IgE Fc receptor as the immunogen.</p>

<p>Peptide H-GKQGGKVR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine, dihydrochloride is a ligand that binds to and activates the receptor. It has been used as a research tool in cell biology to study ion channels and protein interactions. 6Et4TTP has also been used as an inhibitor of peptides and antibodies. The chemical name for this compound is 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl]thieno[2,3d]pyrimidine, dihydrochloride. The CAS number for this compound is 1934302 - 23 - 4.</p>

<p>Peptide H-EPQTTVIHNPDGNK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TQETNKVETY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>BI 9564 is a small molecule that binds to the bromodomain and interacts with the histone acetyltransferase activity, which is involved in inflammatory diseases. BI 9564 also has anti-cancer effects, and can be used for the treatment of various types of cancer, including pancreatic cancer. It inhibits the growth of stem cells, which are important for kidney function. BI 9564 has been shown to induce cell death in glomerular filtration rate cells, cardiac muscle cells and growth factor-dependent cells.</p>

<p>Peptide H-TGKFC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TVRHPEW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AYGRKKRRQRRR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Amino-dPEG®36-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®36-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Peptide H-SSTGPGEQLR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-HGEGTFTSDVSSYLEEQAAK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>MSC1094308 is a molecule that inhibits the replication of viral DNA. It has been shown to be active against a broad range of viruses, including HIV, poliovirus, herpes simplex virus type 1 and influenza A virus. MSC1094308 also exhibits anti-cancer and anti-inflammatory properties, which may be due to its ability to induce autophagy. The mechanism of action for this drug is not yet known.</p>

<p>Bufotalidin is a caffeic acid derivative that has been shown to have inhibitory properties on the heart and locomotor activity. Bufotalidin was shown to decrease the cardiac contractility of isolated rat hearts by inhibiting calcium influx. It also inhibits basic protein kinase C (PKC) in HL-60 cells, which may be due to its ability to inhibit PKC translocation from the cytosol to the membrane. Bufotalidin also has an inhibitory effect on autophagy, which is a process that breaks down cellular components. The molecular mechanisms underlying these effects are not yet understood.</p>

<p>Peptide H-SQVMNLHNL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EHHG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>