Bioquímicos e reagentes

<p>H-Asp-Gly-OH is a peptide hormone that belongs to the group of hydroxylated aspartic acid. This peptide hormone has been shown to be a lymphocyte transformation factor in vitro and stimulates the production of collagen and other proteins. It has also been shown to have anticarcinogenic effects on bone cancer cells, which may be due to its ability to induce apoptosis. H-Asp-Gly-OH has a neutral pH and forms stable complexes with metal ions, such as copper and zinc, which are important for a variety of biological functions.</p>

<p>DT2216 is a small-molecule anticancer compound, which is a product of rational drug design originating from advanced chemical synthesis techniques. The primary mode of action of DT2216 involves selectively targeting and disrupting BCL-XL interactions with pro-apoptotic proteins. By specifically degrading BCL-XL, DT2216 enhances the induction of apoptosis in cancer cells, thereby addressing the challenge of resistance associated with conventional therapies.</p>

<p>Disulfide bond is a covalent chemical bond that links two sulfur atoms to each other. Disulfides are the major form of sulfur-containing proteins, and are important in many biological processes, such as postnatal development, biliary function, hepatitis diagnosis and cancer. Disulfide bonds can be detected using chromatographic methods such as high performance liquid chromatography (HPLC) or gas chromatography (GC). The biosynthesis of disulfides is an essential process in the metabolism of glutathione. Disulfide bonds are formed by the oxidation of two sulfhydryl groups (-SH) in a protein by reactive oxygen species (ROS), which results in the formation of a single disulfide bond between two cysteine residues. This reaction requires glutathione as a cofactor, which catalyzes the formation of -S-S- bridges between two cysteine residues by reducing them to their corresponding thiols (-SH). Glutathione also</p>

<p>3-Indolepropionyl-coa is a potent inhibitor of cancer cell cycle and has been found to induce apoptosis in human cancer cells. This compound is an analog of the naturally occurring urinary metabolite, indole-3-acetic acid, which has been shown to have anticancer properties. 3-Indolepropionyl-coa is a promising medicinal compound for the development of novel anticancer drugs due to its ability to inhibit protein kinase activity in Chinese hamster ovary cells. It has also been reported to inhibit tumor growth and proliferation by blocking the production of cyclin-dependent kinases, which are essential for cell division. The potential use of 3-Indolepropionyl-coa as a therapeutic agent for cancer treatment warrants further investigation.</p>

<p>UM729 is an advanced surface coating, which is a chemical formulation with the aim of enhancing surface durability and protection. Sourced from novel polymeric materials, UM729 is designed to form a robust and resilient layer when applied to various substrates. Its mode of action involves cross-linking at the molecular level, creating a cohesive barrier that offers resistance to environmental factors such as abrasion, moisture, and UV radiation.</p>

<p>Please enquire for more information about 3-Bromo-L-thyroxine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aptiganel (CAS No. 137159-92-3) is a research tool that can be used to study the interaction of proteins and peptides with ion channels. It is an inhibitor of ion channels that blocks the flow of ions through them, thereby preventing the generation of action potentials. Aptiganel is a potent inhibitor of voltage-dependent calcium channels, which are found in neurons and muscle cells. This drug binds to ligands on the extracellular side of ion channel receptors and prevents ligand binding to the receptor, blocking ion flow. Aptiganel has been shown to inhibit voltage-gated potassium channels in rat dorsal root ganglion cells, human neuroblastoma cells grown in culture, and cultured mouse embryo spinal cord neurons. Aptiganel also inhibits voltage-gated sodium channels in rat dorsal root ganglion cells and cultured mouse embryo spinal cord neurons.</p>

<p>LHRH (1-5) (free acid) trifluoroacetate salt is a synthetic hormone that is used in the treatment of prostate cancer. It inhibits the release of luteinizing hormone and follicle-stimulating hormone from the anterior pituitary gland, which suppresses testosterone production by the testes. LHRH (1-5) (free acid) trifluoroacetate salt is synthesized industrially using a liquid phase synthesis. The product may be recycled by returning it to the manufacturing process or using it as an additive for plastics or other industrial products. LHRH (1-5) (free acid) trifluoroacetate salt was shown to be active against tumor cells in culture and inhibited cell growth in culture. This drug has been shown to inhibit the production of nitric oxide, which may contribute to its anti-tumor activity. LHRH (1-5) (free acid)</p>

<p>Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester is a synthetic chemical compound used primarily in advanced organic synthesis. It is derived from benzoic acid and functionalized with a pyrazole moiety, enhancing its reactivity and versatility in chemical transformations. This compound acts as an intermediate in the synthesis of more complex molecules, playing a crucial role as a precursor or reagent due to its unique structure, which facilitates targeted chemical modifications.</p>

<p>1-Palmitoyl-rac-glycero-3-phosphocholine is a biological lipid that has been shown to be a potent growth factor for cells in culture. It binds to DNA and modulates transcriptional regulation. 1-Palmitoyl-rac-glycero-3-phosphocholine also inhibits the production of lysophosphatidylcholine, which is an inflammatory mediator that promotes the release of histamine from mast cells. This compound may be useful as an antimicrobial agent, as it has been shown to inhibit the growth of bacteria and fungi.</p>

<p>FAPI-46 trifluoroacetate is a fibroblast activation protein (FAP) inhibitor, which is synthesized as part of targeted cancer research efforts. It is derived from chemical engineering processes focusing on the modification of small molecules to selectively interact with FAP, an enzyme overexpressed in cancer-associated fibroblasts (CAFs) within the tumor microenvironment. FAPI-46 binds to and inhibits FAP, reducing its enzymatic activity. By blocking FAP, FAPI-46 trifluoroacetate disrupts the tumor-promoting interactions between CAFs and tumor cells, potentially impeding tumor growth and progression.</p>

<p>L-a-Phosphatidylcholine (PC) is a phospholipid that is present in all living cells. It is the major component of biological membranes and is essential for maintaining cell membrane integrity. PC 20 is a purified form of L-a-Phosphatidylcholine, made from soybean extract. The purity of PC 20 has been shown by its ability to inhibit nitrite ion production from soybean extract in vitro. PC 20 also has low bioavailability, meaning that it may not be absorbed well into the bloodstream following oral consumption. This may be due to the uptake of PC 20 by other organs and tissues in the body, such as the liver or spleen, before it can be transported to the blood stream. Further research is needed to determine how PC 20 affects colorectal adenocarcinoma cells.</p>

<p>TFA salt</p>

<p>Sermorelin acetate is a synthetic peptide, which is an analogue of the naturally occurring growth hormone-releasing hormone (GHRH). It is derived from recombinant DNA technology, representing the first 29 amino acids (1-29) of endogenous GHRH. Its mode of action involves binding to and activating the GHRH receptor on the anterior pituitary gland, which subsequently stimulates the release of growth hormone (GH) into the bloodstream.</p>

<p>Involved in the metabolism of fatty acids and amino acids</p>

<p>Cefuroxime-d3 is intended for use as an internal standard for the quantification of cefuroxime, FA19881.  Cefuroxime is a cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria.</p>

<p>Thymopentin acetate salt H-Arg-Lys-Asp-Val-Tyr-OH acetate salt is an experimental model system that has been shown to replicate the physiological effects of thymopoietin in vitro. It has also been shown to inhibit the growth of Candida glabrata, a fungus that causes infection in patients with HIV or AIDS. Thymopentin acetate salt H-Arg-Lys-Asp-Val-Tyr-OH acetate salt has been shown to activate both toll like receptor and IL2 receptor, which may be due to its ability to stimulate polyamine synthesis.</p>

<p>Vancomycin methyl ester is an analog of the antibiotic vancomycin that has been shown to have anticancer properties. It induces apoptosis in cancer cells, particularly in Chinese hamster ovary (CHO) cells and human tumor cell lines. Vancomycin methyl ester acts as a cyclin-dependent kinase inhibitor by binding to the ATP-binding site of these kinases, thereby inhibiting their activity. This protein kinase inhibition leads to the downregulation of proteins involved in cell cycle progression, such as cyclin D1 and E2F1, ultimately leading to cell death. Vancomycin methyl ester has also been found to inhibit the growth of certain types of cancer cells by blocking angiogenesis, which is the formation of new blood vessels that tumors need for their growth and survival. Additionally, this compound has been detected in human urine after administration and may have potential therapeutic applications in cancer treatment.</p>

<p>PI3K-gamma inhibitor 1 is a small molecule inhibitor, which is selectively synthesized for targeting the PI3K-gamma isoform. This inhibitor is derived through precise medicinal chemistry, involving the synthesis of compounds that specifically interact with the catalytic domain of the phosphoinositide 3-kinase gamma (PI3K-γ) enzyme. Its mode of action involves the selective inhibition of the PI3K-γ pathway, a critical signaling route responsible for modulating immune cell functions and inflammatory responses.</p>

<p>Please enquire for more information about Cagrilintide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Guaiacin is a guaianolide that is an inhibitor of the protein phosphatase 1 (PP1). It has been shown to bind to PP1 and inhibit its activity, leading to increased levels of the cellular messenger cAMP. Guaiacin has also been shown to activate PP2A, which may contribute to its anti-inflammatory effects. Guaiacin has been used as a research tool in cell biology and pharmacology studies. It is available in high purity and can be used as an antibody reagent for immunocytochemistry.</p>

<p>Benzoylecgonine antibody was raised in mouse using benzoyl ecgonine-BSA as the immunogen.</p>

<p>ROPA or resiniferonol 9,13,14-orthophenylacetate is an analogue of resiniferatoxin that has been shown to have synergistic interactions with detergents, such as Tween-80, in the removal of wheat germ agglutinin (WGA) from Brucella. ROPA is also active against herpes simplex virus and tumour necrosis factor-alpha (TNF-α). When combined with a basic protein, it can activate the receptor and inhibits the formation of dry weight. ROPA has been shown to be able to inhibit the growth of infectious bacteria, such as those that cause tuberculosis or brucellosis. The mechanism for this inhibition is not clear, but may be due to its ability to bind to water molecules and inhibit their binding with bacterial cytoplasmic membranes.</p>

<p>CA 125 antibody (biotin) was raised in mouse using affinity pure human CA 125 antigen as the immunogen.</p>

<p>Isodesmosine is an amino acid and naturally occurring cross-linking compound, which is primarily found in elastin, a key protein in connective tissues. Its source is the structural protein elastin, where it forms stable cross-links that contribute to the elasticity and resilience of various tissues, notably the skin, lungs, and blood vessels. The mode of action of isodesmosine involves its integration into the elastin matrix, providing durability and elasticity through covalent bonding within and between polypeptide chains.</p>

<p>18:0 PE-DTPA is a cationic amphiphile that is composed of 18:0 phosphatidylethanolamine (PE) and DTPA. It has a strong affinity for gadolinium, which is used in MRI imaging. 18:0 PE-DTPA micelles are used to deliver gadolinium to the target site where it accumulates inside cells. The accumulation of gadolinium in cells can be detected by MRI.</p>

<p>Steroid Free Serum is a high-quality serum that is free from steroids. It is commonly used in various Life Sciences applications, including research and diagnostic assays. This serum contains important components such as alpha-fetoprotein, angiotensin-converting enzyme, collagen, erythropoietin, pegylated growth factor, chemokines, and antibodies with neutralizing properties.</p>

<p>Please enquire for more information about Taurolithocholic acid-d4 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl N,N-bis(1-methylethyl)phosphoramidochloridite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alprostadil alfadex is a medicinal drug that has been found to have anticancer properties. It works by inhibiting the growth of cancer cells and inducing apoptosis, or programmed cell death. This drug is an analog of a naturally occurring protein that acts as a tumor inhibitor in humans. Alprostadil alfadex has been shown to be effective against various types of cancer, including those found in the urinary tract and prostate. It works by blocking the action of certain enzymes and proteins involved in the cell cycle, thereby preventing cancer cells from dividing and multiplying. Chinese researchers have also found that this drug has a kinase-inhibiting effect, which may contribute to its anticancer activity.</p>

<p>Please enquire for more information about IR-806 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3'-Hydroxybupivacaine is an analog of the local anesthetic bupivacaine that has shown potential as an anticancer agent. It acts as a kinase inhibitor, which can prevent the growth and spread of cancer cells. 3'-Hydroxybupivacaine has been found in human urine samples and has been shown to induce apoptosis in tumor cells. This drug is also effective against a variety of Chinese hamster ovary (CHO) cell lines, indicating its broad-spectrum activity against cancer cells. Additionally, 3'-Hydroxybupivacaine has been shown to enhance the anti-tumor effects of other protein kinase inhibitors, such as oseltamivir. Overall, this drug shows promise as a potential therapeutic option for cancer treatment.</p>

<p>β-Chlornaltrexamine dihydrochloride (β-CNTA) is a non-competitive antagonist of the kappa opioid receptor. It has been shown to inhibit camp levels and whole-cell recordings in cells expressing the G protein, guanine nucleotide binding proteins, and ryanodine receptor. β-CNTA also inhibits locomotor activity in mice and reverses the effects of morphine on rotarod performance. In addition, β-CNTA has been shown to be effective against human cell line HL60.END&gt;</p>

<p>Please enquire for more information about (Pyr³)-Amyloid B-protein (3-42) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Acetylpiperazine-N-(4-phenol) ketoconazole is an analog inhibitor that has been shown to inhibit the activity of several kinases. This compound has been tested against a variety of cancer cells and has demonstrated potent anticancer activity, inducing apoptosis in Chinese hamster ovary cells. N-Acetylpiperazine-N-(4-phenol) ketoconazole also inhibits the activity of dapoxetine, a drug used to treat premature ejaculation. In addition to its anticancer properties, this compound has shown promise as an anti-inflammatory agent due to its ability to inhibit the production of prostaglandins. This inhibitor can be detected in urine and may have potential therapeutic applications in the treatment of various cancers.</p>

<p>H-Glu-Gly-Arg-chloromethylketone trifluoroacetate salt is an anticoagulant drug that prevents the formation of blood clots by inhibiting the enzyme thrombin. This drug is effective in enhancing blood flow and oxygen supply to the heart and other organs. H-Glu-Gly-Arg-chloromethylketone trifluoroacetate salt has been shown to have a positive effect on patients with congestive heart failure. It has also been used as an adjuvant therapy in bypassing procedures, where clotting occurs at the site of an artificial conduit placed in the body to allow blood flow between two points. In vitro studies have demonstrated that this drug inhibits protease activity, which may be due to its ability to inhibit fibrinogen and serine protease activity.</p>

<p>Vasopressin receptor agonist; antidiuretic</p>

<p>Z-VRPR-FMK trifluoroacetate is an apoptosis-inducing inhibitor that works by inhibiting a specific kinase in the human body. It has been shown to have anti-cancer properties and may be useful in the treatment of various types of cancer. Z-VRPR-FMK trifluoroacetate is a menthol analog that acts as an inhibitor of apoptosis, which is the process by which cells die naturally. This compound has been tested on Chinese hamster ovary cells and has been found to be effective at inducing apoptosis in these cells. Additionally, Z-VRPR-FMK trifluoroacetate has been shown to inhibit tylosin-induced apoptosis in human colon cancer cells. Overall, this compound shows promise as a potential therapeutic agent for the treatment of cancer and other diseases.</p>

<p>Methotrexate Conjugate for use in immunoassays</p>

<p>GC-globulin is a protein that is found in human plasma. It can be used as an activator, inhibitor, or ligand for ion channels, receptors, and other proteins. GC-globulin has been shown to inhibit the function of receptor tyrosine kinases on B-cells with antibodies that bind to the Fc region of the protein. This inhibition prevents activation of the B-cell receptor and thus inhibits antibody production by B cells. GC-globulin also binds to peptides during cell division and functions as a cofactor for proteolytic enzymes such as plasminogen activator (PA). GC-globulin has been shown to activate PA which leads to fibrinolysis.</p>

<p>Fluorescent derivative of cyclopamine</p>

<p>Please enquire for more information about H-Gly-Leu-Gly-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-glucosidase inhibitor; anti-diabetic</p>

<p>Peptide 5-azido-pentanoyl-RKKRRQRRR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Please enquire for more information about H-Leu-Leu-Gly-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The Methotrexate antibody is a monoclonal antibody that specifically targets and binds to Methotrexate, a commonly used cytotoxic drug in the field of Life Sciences. This antibody has been extensively tested and validated for its high affinity and specificity towards Methotrexate. It can be used in various applications such as ELISA, Western blotting, immunohistochemistry, and flow cytometry. The Methotrexate antibody works by binding to Methotrexate molecules and preventing their interaction with their target enzymes involved in DNA synthesis. This inhibits the growth of cancer cells and autoimmune responses mediated by activated T-cells. Additionally, this antibody can also be utilized as a tool for studying the intracellular localization and trafficking of Methotrexate within cells. The unique features of this Methotrexate antibody include its ability to recognize both free Methotrexate molecules as well as Methotrexate conjugated to proteins or other biomolecules. It exhibits minimal cross-reactivity with</p>

<p>Please enquire for more information about Ethyl N,N,N',N'-Tetraisopropylphosphorodiamidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>LY 117018 is a dopamine analog that binds to the toll-like receptor and blocks the production of proinflammatory cytokines. LY 117018 also inhibits epidermal growth factor (EGF) in liver cells and cyclin D2, which is involved in cell cycle regulation. This drug has been shown to be effective in a model system using fetal bovine serum with angiogenic factors, such as vascular endothelial growth factor (VEGF). The effect on blood vessels was dose-dependent for LY 117018. This drug potentiates the actions of 17β-estradiol on mcf-7 cells and serum prolactin levels are significantly decreased in vivo by this compound.</p>

<p>FluM1 (58-66) is a short part of the matrix protein of Influenza A virus which is the most abundant component of this enveloped virus localized under the viral lipid envelope. The GILGFVFTL epitope is highly conserved in Influenza A virus strains at a rate of 93% for 69 strains tested. Human Influenza epitopes may bind MHC molecules and then may be recognized by CD8+ cytotoxic T cells. Applications of FluM1 (58-66): FluM1 (58-66) is used to stimulate CTL responses in peripheral blood mononuclear cells (PBMCs). Then, ELISPOT assay is used to quantify peptide epitope specificity and IFN-γ releasing effector cells. FluM1 (58-66) has shown CTL responses qualified of immunodominant with restriction by HLA-A*02:01. It has also been detected CTL responses when FluM1 (58-66) is restricted by all HLA-C. Therefore, FluM1 (58-66) may help to understand the reaction of immune system against Influenza virus of each populations having different HLA type. FluM1 (58-66) has indeed prompted research to develop T-cell vaccine strategies capable of inducing specific CTL responses in patients upon immunization with Influenza M1 antigenic epitope. MVA-NP+M1 vaccine use GILGFVFTL epitope and is tested in clinical trial. Potential cross-reactivity with HIV-1 p17 Gag (77-85): Moreover, FluM1 (58-66) share similarities with HIV-1 p17 Gag (77-85) which can potentially show a cross-reactivity between these epitopes. It has been demonstrated a cross-reactivity and results suggest that immunity following infection by Influenza virus causes specific immune response to HIV-1 p17 Gag (77-85).</p>

<p>UK 383367 is a chemical compound classified as a synthetic small molecule, which is derived from a meticulously controlled chemical synthesis process. Its mode of action involves modulating specific biochemical pathways by binding to target receptors, thereby influencing cellular processes at a molecular level. This compound is utilized extensively in pharmaceutical research for its potential therapeutic effects, particularly in the context of investigating receptor activity and signaling pathways. Additionally, UK 383367 finds applications in various industrial processes, serving as an intermediate in the synthesis of more complex compounds. Due to its precision in targeting and influencing biological systems, UK 383367 is a valuable tool for scientists seeking to elucidate the mechanistic pathways underlying disease and for the development of novel therapeutic strategies.</p>

<p>ALX-1393 is a synthetic compound that acts as an inhibitor, specifically targeting the glycine transporter 1 (GlyT1). As a small molecule inhibitor derived from chemical synthesis, it modulates neurotransmitter systems by blocking the reuptake of glycine, an important co-agonist of the NMDA receptor, in the central nervous system. The mode of action of ALX-1393 involves binding to the GlyT1 transporter, thereby increasing the synaptic concentration of glycine. This elevation in glycine levels enhances NMDA receptor function, which is crucial for synaptic plasticity, learning, and memory.</p>

<p>Please enquire for more information about 1-(Carboxymethyl)-1H-benzo[G]indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Diynes are a group of unsaturated fatty acids that have two carbon-carbon double bonds. 16:0-23:2 Diyne pe is a growth factor that has been shown to increase the proliferation of prostate cancer cells in vitro. It has also been shown to stimulate angiogenesis, or the formation of new blood vessels from pre-existing ones. It has been found to be an important prognostic factor for cervical cancer and may be used as a predictive marker for prognosis and treatment. This compound is present in human serum at low levels and is increased by liver damage, inflammation, or other diseases such as hepatitis. 16:0-23:2 Diyne pe may also play a role in preeclampsia and cell culture, where it stimulates cell proliferation. In addition, this compound may act as a receptor for fatty acid metabolism.</p>

<p>The hCG protein is a growth factor that plays a crucial role in various biological processes. It is involved in the regulation of cell growth, differentiation, and development. This protein has been extensively studied in the field of Life Sciences and has shown promising results in various applications. One of the key characteristics of the hCG protein is its ability to interact with arginase, an enzyme involved in the metabolism of arginine. Through molecular docking studies, it has been shown that hCG can bind to arginase and modulate its activity, leading to potential therapeutic applications. Monoclonal antibodies targeting the hCG protein have been developed for research purposes. These antibodies are highly specific and can be used in immunoassays to detect and quantify hCG levels in human serum samples. They have also been used for the immobilization of hCG on electrodes, enabling the development of biosensors for diagnostic purposes. Furthermore, studies have demonstrated that the hCG protein plays a role in the regulation of mes</p>

<p>Peptide H-ASCLYGQLPK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>This peptide is a research tool that has been shown to activate the ATP-sensitive potassium ion channel, which is found in the membranes of many cells. This peptide also binds to the beta2-adrenergic receptor and has been shown to inhibit the activity of protein kinase C. The CAS number for this peptide is 400863-77-6.</p>

<p>Please enquire for more information about H-Gln-pNA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ala-Ala-Ala-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-(3-Chlorostyryl)caffeine is a caffeine derivative that binds to the adenosine A3 receptor. It has been shown to inhibit locomotor activity and increase diastolic pressure in knockout mice lacking the adenosine A3 receptor. 8-(3-Chlorostyryl)caffeine has also been shown to have inhibitory properties on cyclase, which is necessary for the production of cAMP, the second messenger in cells. This drug also inhibits dopamine release from neurons and hydrogen bond formation with DNA, protein, and other biomolecules. Lastly, 8-(3-Chlorostyryl)caffeine can bind to both A1 and A2A receptors as well as to dna binding sites.</p>

<p>Please enquire for more information about H-Val-Val-Val-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>TES, also known as N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid, is a buffering agent that is used in protein assays and forms complexes with DNA and copper ions. The optimal pH range of this zwitterionic buffer is 6.8-8.2 and its pKa is 7.4.</p>

<p>Retroprogesterone is a human urine-derived compound that has shown promising results in the field of cancer research. It is an analog of oseltamivir and acts as a kinase inhibitor, which makes it an effective anticancer agent. Retroprogesterone has been shown to induce apoptosis in cancer cells by inhibiting protein kinases that are essential for cell survival and proliferation. This compound has demonstrated potent tumor growth inhibition in Chinese hamster ovary cells, making it a potential candidate for cancer therapy. Retroprogesterone has also been studied as an inhibitor of various kinases involved in cancer development and progression. Its ability to target multiple pathways involved in cancer makes it a valuable tool for future research and drug development.</p>

<p>μ- and κ- opioid receptor antagonist; partial agonist of δ- opioid receptors</p>

<p>Please enquire for more information about Cerebellin trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Mucin antibody was raised in mouse using Mucin isolated from ovarian mucinous cysts and colonic mucosa as the immunogen.</p>

<p>PF2562 is a potent and selective activator of the metabotropic glutamate receptor mGluR5. It is a competitive antagonist at AMPA receptors, with no activity at NMDA or kainate receptors. PF2562 is known to inhibit protein interactions between the proteins encoded by the gene for the metabotropic glutamate receptor mGluR5 and its ligands, such as l-glutamic acid and d-serine. This inhibition leads to activation of these receptors, which may be important in research on neurological disorders and other diseases involving glutamate signaling.</p>

<p>Imidazole-15N2 is an analog of the calcium channel blocker nifedipine that has been shown to have anticancer properties. It induces apoptosis in cancer cells by inhibiting protein kinases, which are involved in tumor growth and survival. Imidazole-15N2 has been studied in both Chinese hamster ovary cells and human cancer cell lines, where it has demonstrated potent inhibition of kinase activity. This drug is a promising candidate for the development of novel cancer therapies due to its ability to selectively target cancer cells while sparing normal cells. Imidazole-15N2 can be detected in urine and may serve as a biomarker for the presence of protein kinase inhibitors in the body.</p>

<p>Siratiazem is a calcium-channel blocker that is used for the treatment of cardiac arrhythmia and hypertension, as well as for the prevention of congestive heart failure. Siratiazem is a prodrug that is converted to its active form by hydrolysis in the liver. It binds to the L-type calcium channels in cardiac muscle cells, thereby blocking calcium influx and decreasing the excitability of these cells. This drug has been shown to be effective in phase 1 clinical trials, with no major adverse effects. Siratiazem can cause symptoms such as nausea, vomiting, diarrhea, or constipation and may also have effects on insulin resistance and ventricular dysfunction.</p>

<p>2-Benzyl-2,8-diazaspiro[4.5]decan-1-one hydrochloride is a chemical compound utilized chiefly in pharmacological research. It is synthesized through organic chemical processes designed to produce spirocyclic frameworks that can interact specifically with biological macromolecules. The compound acts as a ligand in receptor studies, allowing researchers to investigate the binding properties and activities at selective receptor subtypes.</p>

<p>Please enquire for more information about Opiorphin trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Oligopeptide-51 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Endogenous heptapetide which causes vasodilation and has anti-hypertensive properties.</p>

<p>Recombinant canine thyroid-stimulating hormone (TSH)</p>

<p>3,4-Dihydro-2(1H)-isoquinolinyl)[2-[(4-methoxyphenyl)amino]-4-thiazolyl]methanone is a potent and selective inhibitor of the ion channel TRPM8. It reduces pain and inflammation by inhibiting the action of TRPV1 and TRPA1. 3,4-Dihydro-2(1H)-isoquinolinyl)[2-[(4-methoxyphenyl)amino]-4-thiazolyl]methanone is an inhibitor of the TRPM8 ion channel with IC50 value of 0.06 μM. 3,4-Dihydro-2(1H)-isoquinolinyl)[2-[(4-methoxyphenyl)amino]-4-thiazolyl]methanone inhibits TRPA1 with IC50 value of</p>

<p>Please enquire for more information about 1,8-Dinitropyrene-d8 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>A novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

<p>D-Hyoscyamine is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cell growth and division. D-Hyoscyamine has been tested on both human and Chinese hamster ovary cells, and has demonstrated significant anticancer activity. It is an analog of several kinase inhibitors, including cyclin-dependent kinase (CDK) inhibitors, which are commonly used in cancer therapy. In addition to its anticancer properties, D-Hyoscyamine has also been found to have potential therapeutic applications for other diseases such as Alzheimer's disease and Parkinson's disease. It is derived from urine and acts as a potent inhibitor of protein kinases.</p>

<p>N-Desethyl N-methyl rivastigmine is an analog of rivastigmine and a potent inhibitor of kinases. It has been shown to induce apoptosis in cancer cells, making it a promising candidate for the treatment of various types of tumors. This medicinal compound is excreted through urine and has been found to have anticancer properties by inhibiting protein kinases. In Chinese hamster ovary cells, N-Desethyl N-methyl rivastigmine was found to inhibit the activity of several kinases involved in cell proliferation and survival. This inhibitor has potential therapeutic applications for cancer treatment due to its ability to target specific kinases that are essential for tumor growth and progression.</p>

<p>a brain-penetrating activator of eukaryotic initiation factor 2B (eIF2B) that inhibits the abnormal integrated stress response</p>

<p>Please enquire for more information about Bromantane-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Pheromone Cymit Quimicaesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sheep polyclonal Mescaline antibody</p>

<p>Pseudoisoeugenyl 2-methylbutyrate is an analog of astaxanthin that has shown promising results in inhibiting tumor growth and inducing apoptosis in cancer cells. It acts as a kinase inhibitor, preventing the replication of cancer cells and promoting anticancer effects. Pseudoisoeugenyl 2-methylbutyrate has been tested on human and Chinese hamster ovary cell lines, demonstrating its potential as a potent anticancer agent. This compound has also been found in urine samples, suggesting that it may have natural sources in the body. Its ability to inhibit kinases makes it a promising candidate for further research into cancer treatment.</p>

<p>S-Lenalidomide is a drug that is used to treat cancer and autoimmune diseases. It is an immunomodulatory agent that induces cytokine release and inhibits the production of interleukin-2 (IL-2) by T cells. This drug also has a concentration-dependent effect on the activity of oxidative enzymes, such as benzalkonium chloride and light emission. S-Lenalidomide has been shown to be clinically relevant in infectious diseases, with concentrations producing significant effects on disease activity. The water vapor stability of this drug makes it suitable for use in humid environments such as those found in developing countries. S-Lenalidomide has been shown to induce antitumor responses without causing immunosuppression or toxicity in rats.</p>

<p>Please enquire for more information about HYYYGAAPPGQKGQANATRIPAKTPPAPK{pT}PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP{pT}PPTREPKKVA-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Secologanate is a peptide that has been used as a research tool to study the interactions between proteins and ligands. Secologanate is an inhibitor of ion channels, which are membrane-spanning proteins that control the flow of ions in and out of cells. It also inhibits protein interactions by blocking the binding site on one molecule for a second molecule. Secologanate has been shown to inhibit the ion channel TRPV1, which is involved in pain sensation. Secologanate has also been shown to be a ligand for the human angiotensin II receptor type 1 (AT1R).</p>

<p>Foslevodopa is a prodrug that is converted to levodopa in the body. This drug has been shown to be safe and effective for the treatment of Parkinson's disease with minimal side effects, although it does not affect the progression of the disease. Foslevodopa is a synthetic compound that has been synthesized using chemical methods. It can be manufactured in large quantities, making it a scalable pharmaceutical formulation.</p>

<p>L-MobileTrex is an advanced analytical technology platform, which is a product of cutting-edge research in data science and computational modeling. This platform operates by integrating multi-dimensional datasets through sophisticated algorithms, providing enhanced data visualization and interpretability.</p>

<p>Purified native Human CEA protein (Preservative-free)</p>

<p>Please enquire for more information about Cyclo(L-alanyl-L-tryptophyl) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>