Bioquímicos e reagentes

<p>Lamin B1 (321-330) is derived from the nuclear envelope protein, Lamin B1 which plays a role in the regulation of epigenetic chromatin. The lysine residue at position 10 is isotopically labelled with carbon-13 (6) and nitrogen-15 (2).</p>

<p>Normal Guinea Pig Serum is a veterinary product that is commonly used in various applications. It is known for its photostability and contains essential components such as glycan, human serum, glycoprotein, and glycosylation. This serum is activated and can be used in experiments involving farnesyl transferase and glycopeptide. Additionally, Normal Guinea Pig Serum is often utilized in the life sciences field for research purposes, including the development of monoclonal antibodies and chemokines. It is an important biospecimen that provides valuable insights into various biological processes.</p>

<p>Peptide H-AVQQPDGLAVLGIFLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-HNLFEPEDTGQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide ttpa-SGSG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SNLELLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LLVPANEGDPTETLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-STGGAPTFNVTVTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>E. coli O157 antibody was raised in mouse using the 'O' antigen of E. coli serotype O157 as the immunogen.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>KLH antibody is a monoclonal antibody used in Life Sciences research. It has cytotoxic properties and can specifically target various molecules, including TNF-α, collagen, and alpha-synuclein. This monoclonal antibody is highly specific and can be used to study the role of these molecules in different biological processes. Additionally, KLH antibody has been shown to inhibit the activity of growth factors such as hepatocyte growth factor (HGF) and transforming growth factor-β1 (TGF-β1). Furthermore, this antibody has potential therapeutic applications in the treatment of thrombocytopenia and as a family kinase inhibitor for epidermal growth factor receptors. Its versatility makes it a valuable tool for researchers in the field of Life Sciences.</p>

<p>Peptide H-YNGIITDTI^K-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Oxybutynin is an antimuscarinic agent that is used to aid the bladder in relaxing and preventing the urge to void. This drug is used in the treatment of an overactive bladder and reduces detrusor muscle activity. Oxybutynin works by inhibiting the action of acetylcholine on smooth muscle.</p>

<p>Peptide LCBiot-SGVYKVAYDWQH-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Purified native Bovine 200 kDa Neurofilament protein</p>

<p>H-DMLSELSTIMNEQIMCR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-DMLSELSTIMNEQIMCR-OH is provided at greater that Flashpure (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-DMLSELSTIMNEQIMCR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-DMLSELSTIMNEQIMCR-OH at the technical inquiry form on this page</p>

<p>Peptide Aoa-ATCYCRTGRCATRESLSGVCEISGRLYRLCCR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-PQNLLLDPDTAVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-CTPYDINQM-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-FLRGRAYGL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Residues 1-10 of the gastrointestinal hormone motilin, secreted from endocrine cells in the small intestines, mainly from the jejunum and duodenum, in response to the fasting, drinking water or the mechanical stimulus of eating.</p>

<p>Peptide H-YFIIQDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Purified Bovine IgG (Fc) FITC conjugate</p>

<p>Highly purified native Human RBP protein</p>

<p>Lysostaphin is a bacteriolytic enzyme that is produced by the bacteria Staphylococcus simulans. It cleaves the cross-linked pentaglycine bridges in bacterial cell walls which are essential for their structural integrity. Lysostaphin displays a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The recombinant form of lysostaphin has been expressed in E. coli and can be used to produce large quantities of lysostaphin for therapeutic use. Expression of lysostaphin in E. coli has also allowed for the production of other polypeptides with antimicrobial properties, such as the clostridial bacteriocins and staphylokinase.</p>

<p>The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is a potent antituberculosis drug from the rifamycin class. It is highly effective in treating tuberculosis infections due to its bactericidal activity. This compound works by binding to DNA-dependent RNA polymerase, preventing transcription and replication of bacteria. Its efficacy has been demonstrated through transcription-quantitative polymerase chain reactions and patch-clamp techniques. Additionally, it undergoes various metabolic transformations, including hydrolysis, oxidation, reduction, and conjugation with glucuronic acid. Furthermore, it specifically targets Mycobacterium tuberculosis strains by binding to markers expressed at high levels in these strains.</p>

<p>Elastase antibody was raised in mouse using purified human neutrophil elastase as the immunogen.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Nef is an accessory protein highly conserved amongst all primate lentiviruses, it is essential for viral replication in vivo- it is expressed by human immunodeficiency virus (HIV) HIV-1 and HIV-2. Nef acts as a downregulator of class I human leukocyte antigens (HLA) expression in HIV-infected cells to help circumvent the immune response, such as Cytotoxic T lymphocytes (CTL) activity. An intact nef gene is critical for high viral loads, linked to development of acquired immunodeficiency syndrome (AIDS). Certain alleles of HLA have been associated with maintaining a seronegative status such as HLA-A*1101.This nef peptide sequence contains the region considered to be a a C-proximal adaptor-protein (AP) interaction site. The presence of various nef motifs such as this are an intense area of investigation to understand if they are a factor in patients who remain clinically asymptomatic. This nef fragment is provided with an N-terminal acetyl group to increase its stability.</p>

<p>HBsAg antibody (Subtype ad/ay) was raised in goat using hepatitis B surface antigen as the immunogen.</p>

<p>Ac-KIKSGERGRKGPGPGG-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-KIKSGERGRKGPGPGG-NH2 is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-KIKSGERGRKGPGPGG-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-KIKSGERGRKGPGPGG-NH2 at the technical inquiry form on this page</p>

<p>H-VNRVRKGYSPLSLQT-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VNRVRKGYSPLSLQT-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VNRVRKGYSPLSLQT-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VNRVRKGYSPLSLQT-OH at the technical inquiry form on this page</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Histone 4 (H4) is one of the four core histones (H2A, H2B, H3 and H4) which are essential for compacting eukaryotic DNA into the nucleosome. Due to the high lysine and arginine content, histones have a net positive charge and therefore electrostatically interact with negatively charged DNA. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Like other core histones, H4 has a globular domain and a flexible N-terminal domain, the histone tail, which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination.Gene transcriptional activation or inactivation is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes. Both processes function to alter the positioning of the nucleosome, allowing the DNA within to be either accessible to the transcription machinery or inaccessible. H4 lysine rich tail plays a role in the higher order chromatin folding.The lysine at position 16 has been acetylated, which neutralizes the positive charge on the amino acid, loosening the chromatin structure. This alteration to the accessibility of chromatin promotes the initiation of transcription.Acetyl-Histone H4 (1-23) K16Ac-GG-[Lys(5-FAM)] has a C-terminal GGK linker labelled with 5-Carboxyfluorescein (5-FAM), a widely used green fluorescent tag. Additionally, this peptide has an uncharged C-terminal amide and is protected from N-terminal modifications by a covalently bonded acetyl group.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Selective partial GABAA receptor antagonist of subtypes  α1, α2, α3, α5 subunits. Non-sedative anxiolytic effects demonstrated in vivo, without compromising motor activity. Anti-nociceptive and anti-inflammatory activities also demonstrated in vivo.</p>

<p>The Hepatitis C Virus antibody is a cholinergic antibody used in the field of Life Sciences. It is an androgen that targets specific antigens and growth factors associated with the Hepatitis C Virus. This Monoclonal Antibody works by inhibiting the activity of choline acetyltransferase, an enzyme involved in the synthesis of acetylcholine. By targeting this enzyme, the antibody disrupts the normal functioning of the virus and prevents its replication. Additionally, this antibody has been shown to exhibit cytotoxic effects on infected cells, making it a promising tool for diagnostic assays and potential therapeutic applications. With its high specificity and efficacy, this monoclonal antibody is a valuable asset in Hepatitis C research and treatment.</p>

<p>Peptide H-IPAMVVDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AAGIGILTV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>HMG-CoA reductase inhibitor</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>H-FDMELDDLPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-FDMELDDLPK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-FDMELDDLPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-FDMELDDLPK-OH at the technical inquiry form on this page</p>

<p>ATP6V1E2 antibody was raised in Rabbit using Human ATP6V1E2 as the immunogen</p>

<p>3-(4-[[3-(4-Chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl]methoxy]-3,5-difluorophenyl)propanoic acid is an antibody that is used to study the interactions between proteins in the cell. It can be used to determine the function of ion channels, protein synthesis and cell division. 3-(4-[[3-(4-Chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl]methoxy]-3,5-difluorophenyl)propanoic acid is a high purity reagent for research use only. This antibody has been shown to bind to a receptor of interest with high affinity and specificity. The molecular weight of this antibody is approximately 150 kDa. CAS No. 1628448-77-</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Selective inhibitor of the mutated RET variant RETV804M, which is the anticipated drug-resistant RET mutant that can occur in tumours treated with kinase inhibitors. The compound has a biochemical IC50 of 0.02 µM and selectivity for purified RETV804M over purified RET and KDR of 3.7 and 110, respectively. The efficacy of the compound was shown also in cell cultures with IC50 of 4.4 µM, and cell assay selectivity for RETV804M over RET and KDR of 0.89 and 2.3, respectively.</p>

<p>Peptide Ac-SHAVAS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>