Síntese de Peptídeos

<p>Fmoc-Cys-(CAMTrt)-OH is an amino acid derivative, which is a synthetic compound essential for peptide synthesis. It is derived from natural cysteine, an amino acid found in proteins, and is modified with an Fmoc (9-fluorenylmethoxycarbonyl) protective group and a CAMTrt (trityl sulfonium ion) moiety. This derivative is used primarily in solid-phase peptide synthesis, where the Fmoc group protects the amine during chain elongation, and the CAMTrt group safeguards the thiol function of cysteine, preventing unwanted side reactions during synthesis.</p>

<p>Crosslinker reacting rapidly with primary amines.  It is used as a protein crosslinker where it reacts with cysteine to yield specific conjugates.  The cyclohexane bridge confers added stability to the maleimide group making it ideal for maleimide activation of proteins.  It is soluble in water and many other aqueous buffers although it is less stable then in DMSO or DMF.</p>

<p>Fmoc-Thr(tBu)-D-Ser(Psi(Me,Me)pro)-OH is a speciality chemical that is used as a reagent for peptide synthesis. It is also useful in the synthesis of complex compounds and scaffolds. This compound has high quality with a CAS number of 56610-81-8. Fmoc-Thr(tBu)-D-Ser(Psi(Me,Me)pro)-OH is a versatile building block that can be used in reactions involving amines and carboxylic acids. Fmoc-Thr(tBu)-D-Ser(Psi(Me,Me)pro)-OH is an intermediate that can be used in the synthesis of many different compounds.</p>

<p>Fmoc-N-Me-Asp(OtBu)-OH is a synthetic peptide with potential immunosuppressive properties. It has been shown to inhibit the proliferation of human lymphocytes in response to lipopolysaccharides (LPS) and also to suppress the release of cytokines such as IL-1β, IL-6, and TNFα. The effects were dose dependent and could be reversed by the addition of a neutralizing antibody. This peptide can be used as an immunosuppressant in clinical trials that are investigating treatments for myasthenia gravis. Fmoc-N-Me-Asp(OtBu)-OH has been synthesised using chemical synthesis methods from commercially available reagents.</p>

<p>Please enquire for more information about L-γ-Glutamyl-3-(1-propenylsulfinyl)-L-alanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>LL-37 TFA is a reagent, complex compound and useful intermediate for the fine chemical and pharmaceutical industries. It is also an important building block for the synthesis of other chemicals. LL-37 TFA has CAS No. 71428-08-9, which is a speciality chemical that can be used in research as well as in many different reactions. The versatility of this compound makes it a very useful building block for the synthesis of other chemicals.</p>

<p>4-Hydroxybenzenepropanoic acid 2,5-dioxo-1-pyrrolidinyl ester is a chemical reagent commonly employed in the field of peptide synthesis. This compound, often utilized as a coupling agent, is derived from the esterification of 4-hydroxybenzenepropanoic acid with N-hydroxysuccinimide (NHS).</p>

<p>Fmoc-D-allo-Thr(tBu)-L-Ser(Psi(Me,Me)pro)-OH is a reagent that is used as an intermediate in the synthesis of complex compounds. It is also a fine chemical that can be used to prepare speciality chemicals. Fmoc-D-allo-Thr(tBu)-L-Ser(Psi(Me,Me)pro)-OH has CAS No. and can be used as a reaction component in various reactions. This compound is versatile and can be used as a building block for other compounds.</p>

<p>A novel protected cysteine that can be cleaved by photolysis.</p>

<p>D-methionine is a form of the amino acid methionine that is synthesized in plants. It has been studied for its potential to help with various metabolic disorders, including osteoarthritis and primary sclerosing cholangitis. D-methionine provides methionine to the body, which is essential for the formation of collagen and elastin. In addition, it has been shown to have a protective effect against neuronal death in a model system. D-methionine may be beneficial for people with liver disease, but more research is needed.</p>

<p>Macrophage-activating lipopetide-2 (MALP-2) is a TLR2 agonist and activator of  MyD88-dependent signaling pathways. It has potential as a vaccine adjuvant.</p>

<p>Please enquire for more information about Methyl 2,4-diaminobutanoate dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about L-Lysyl-L-phenylalanyl-L-lysine trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about N-(Triphenylmethyl)-D-asparagine monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Poly-L-lysine hydrochloride, MW20000 is a water soluble polymer with an average molecular weight of 20000 Da. It is used in the synthesis of peptides and proteins due to its high purity, high quality, and low cost. Poly-L-lysine hydrochloride, MW20000 has been shown to bind to a wide range of surfaces such as glass, plastic, silicon dioxide, and stainless steel. This makes it useful for surface modification. Poly-L-lysine hydrochloride can be used as a scaffold for chemical reactions or as an intermediate in the synthesis of complex compounds.</p>

<p>Please enquire for more information about S-2-Propen-1-yl-L-cysteine ethyl ester hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>A useful as an intermediate in the synthesis of peptides, proteins, and other organic molecules. It can be used as a reagent or as an additive to other chemicals.</p>

<p>Boc-L-prolinal is a stereoselective enolate that has been used in the synthesis of organometallic compounds. It is also used in the preparation of monoclonal antibodies, which are proteins that are produced by the immune system to help fight off infections. Boc-L-prolinal has been shown to be an effective agent for treating many cancers, including breast cancer and melanoma. In addition, it has been shown to inhibit epidermal growth factor (EGF) and other growth factors, which may be due to its ability to induce apoptotic signaling. Boc-L-prolinal also contains a carbonyl group, which can undergo acidolysis reactions with nucleophiles such as water or alcohols.</p>

<p>Cbz-L-glutamine is a water soluble compound that is used in the synthesis of pomalidomide. It is synthesized through a stepwise amide formation from methylamine and ethylene diamine. Cbz-L-glutamine has been shown to have an inhibitory effect on cancer cells, which may be due to its ability to break down hydroxamic acids. This chemical reaction causes the release of hydrogen ions, which leads to the disruption of various cellular processes, such as DNA replication and protein synthesis. The uptake of Cbz-L-glutamine by cancer cells has been shown in tissue culture experiments.</p>

<p>Ramage Linker,Fmoc-Suberol is a synthetic derivative of the antimicrobial peptide guanylate. It is used as an inhibitor of congestive heart failure. Ramage Linker,Fmoc-Suberol has been shown to be effective in reducing the severity of congestive heart failure by inhibiting the production of brain natriuretic peptides. The chemical structure and sequence have been determined using a combination of structural analysis and degradable linkers that are cleaved in vivo by hydrolysis or enzymatic degradation. Ramage Linker,Fmoc-Suberol has also been shown to reduce blood pressure and inhibit platelet aggregation.</p>

<p>Solid phase peptide anchor; tool for the Fmoc solid phase synthesis of peptide amides.<br>100-200 mesh. 1% DVB, substitution range 0.3-0.6 meq/g</p>

<p>Fmoc-L-Cys(StBu)-OH is a synthetic molecule that is used in pharmaceutical formulations. It can be synthesized from Fmoc-L-Cys and L-serine methyl ester by the chemical ligation of the two molecules. The chloride group at the end of this molecule provides a functional group for conjugation with other biomolecules, such as fatty acids. This molecule has been shown to have high purity with an isolated yield of about 98%.</p>

<p>Rink amide-AM resin is a cation exchange resin that is used in peptide synthesis. It has an optimal pH range of 8-9. Rink amide-AM resin can be activated with trifluoroacetic acid or piperidine and washed with a mixture of water and methanol to remove the salt byproduct. The resin can then be used for peptide synthesis, which is typically done by adding the desired amino acids in sequence to the resin. The synthesis is stopped when the linear peptide reaches a desired length, typically 12-15 amino acids long. The linear peptides are then cleaved from the resin using trifluoroacetic acid or piperidine, depending on which activation reagent was used during synthesis. After cleavage, the linear peptides are precipitated from solution using ethanol or acetone and collected by filtration.</p>

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<p>Please enquire for more information about H-Lys-Thr-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dopaquinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Glu-Gly-OH is a high quality, versatile building block that is used in the synthesis of complex, high value compounds. It has been shown to be a good reagent for the synthesis of novel natural products and can also be used as a research chemical. H-Gly-Glu-Gly-OH is available as a fine chemical with CAS No. 50997-16-5.</p>

<p>Pexiganan acetate is the acetate salt form of a polymyxin B derivative that has potent antimicrobial activity against both Gram-positive and Gram-negative bacteria. It has been shown to be effective in the treatment of tissue infections, especially those caused by human pathogens such as Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Pexiganan also has significant activity against Mycobacterium tuberculosis and other mycobacteria. The mechanism of action for pexiganan is not fully understood but it may involve the inhibition of bacterial cell wall synthesis, or the disruption of bacterial membranes. Pexiganan was originally isolated from a marine sponge off the coast of Australia in 1961. It had been classified as an antimicrobial peptide (AMP) because of its chemical structure, which includes a polymyxin B moiety. Pexiganan’s AMP classification was later challenged when researchers found that it did</p>

<p>N3-Orn(Boc) cyclohexylamine is a chemical intermediate that is used in the synthesis of complex compounds. It can be used as a building block or an intermediate in the synthesis of many fine chemicals, such as pharmaceuticals, agrochemicals, and fragrances. N3-Orn(Boc) cyclohexylamine is also used in reactions involving amines and alcohols to produce useful scaffolds. This chemical product has been shown to be safe for human use with no significant adverse side effects at doses up to 100mg/kg body weight.</p>

<p>Please enquire for more information about 2-Chlorotrityl chloride resin - (100-200mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Boc-L-homoserine is a lactam with an alkyl group, which makes it a useful synthetic intermediate for the synthesis of various products. It has been used in the synthesis of β-unsaturated ketones and conjugates. N-Boc-L-homoserine is also found naturally in nature and can be found as its two isomers, L-homoserine and D-homoserine. This compound has been shown to have histone deacetylase inhibition activity, which may be due to its ability to inhibit histone acetyl transferase. N-Boc-L-homoserine is synthesized from butyric acid, which is a tetrapeptide that contains four amino acids: valine, leucine, proline, and hydroxyproline.</p>

<p>Trityl-L-phenylalanine diethylamine is a reagent that is used in the synthesis of peptides, reagents, and other chemicals. Trityl-L-phenylalanine diethylamine reacts with an azide to form a triazole. It can also be used to convert an acid into an amino acid. This chemical has been shown to be sensitive to plasmin, which may lead to degradation during peptide synthesis.</p>

<p>N-Cbz-L-homoserine is a synthetic amino acid that has been used in positron emission tomography (PET) studies to determine the uptake and utilisation of other amino acids by biological systems. It has also been used in biological studies to investigate the mechanism of nucleophilic attack by serine on Cbz-protected homoserine. N-Cbz-L-homoserine has been shown to have hepatotoxic effects and may be carcinogenic, but no evidence indicates it is mutagenic or teratogenic. It is highly reactive with acrylonitrile, which can cause it to produce hydrogen cyanide as a result of nitrile hydrolysis.</p>

<p>4-tert-Butyl-L-phenylalanine is a synthetically created antigen with the ability to interact with red blood cells. It has been shown to be a potent probe for the detection of P. falciparum, and can be used as an affinity reagent for the isolation and identification of mutations in the c-terminal region of this protein. 4-tert-Butyl-L-phenylalanine also interacts with P. falciparum apical membrane proteins, which are specific to this type of parasite. This interaction may play a role in its invasion into red blood cells, which is what causes malaria infection.</p>

<p>Fmoc-glycinol is a synthetase that is used to synthesize glycinol conjugates. It binds to the receptor on Gram-positive bacteria and blocks the synthesis of bacterial cell wall, leading to cell death. Fmoc-glycinol has been shown to have high binding constants with amines and an acyl chain, which allows it to bind with antigen. Fmoc-glycinol also has strong nucleophilic properties that allow it to react with chloride ions in water and other polar solvents. This reaction mechanism leads to the formation of a new bond between two molecules, which is called a glycinol linkage.</p>

<p>DL-3-(2-Furyl)serine is a versatile building block that can be used in the synthesis of complex compounds. It has been used as a reaction component and intermediate for research chemicals, speciality chemicals and fine chemicals. DL-3-(2-Furyl)serine has also been found to be useful in the synthesis of high quality reagents.</p>

<p>Fmoc-D-allo-isoleucine is a β-amino acid that is used in the synthesis of calpinactam, a multidrug used to treat tuberculosis. The chemical structure of Fmoc-D-allo-isoleucine has been analyzed by spectroscopic methods and found to be labile. This product is susceptible to hydrolysis and can undergo modifications such as dehydration, oxidation, or racemization. Fmoc-D-allo-isoleucine has shown antimycobacterial activity when tested against M. tuberculosis.</p>

<p>Fmoc-Asp(OtBu)-D-Ser(Psi(Me,,Me)pro)-OH is a high quality, reagent, complex compound, useful intermediate, fine chemical, useful scaffold, and speciality chemical that is used in the synthesis of peptides and other organic compounds. It can be used as a reaction component for the synthesis of peptides and other organic compounds. This building block is versatile with many different functional groups and can be used in a wide variety of reactions. Fmoc-Asp(OtBu)-D-Ser(Psi(Me,,Me)pro)-OH is also a reaction component that can be used to make various drugs or pharmaceuticals.</p>

<p>Bio acrylic resin is a dental material that is composed of a methacrylate-ethylene glycol dimethacrylate copolymer. It is used in the fabrication of dentures and other dental prosthetics. The resin particles are made up of a poly(ethylene glycol dimethacrylate-Methyl methacrylate) blend, which provides strength and durability to the final product. The particle size of the resin is approximately 50 micrometers, ensuring smooth and even application during the manufacturing process. Bio acrylic resin is commonly used in dental laboratories and research facilities for its reliable performance and consistent results.</p>

<p>Boc-L-aspartic acid a-9-fluorenylmethyl ester is a synthetic compound that mimics the structure of acetylcholine. It has been shown to be an efficient method for generating pseudopeptides and cyclic peptides. This compound may be used as a surrogate for acetylcholine in virus research, since it can bind to the same receptor. Boc-L-aspartic acid a-9-fluorenylmethyl ester has also been used to generate monoclonal antibodies that are neutralizing against foot-and-mouth disease viruses.</p>

<p>Fmoc-N-Me-Asn(Trt)-OH is a peptidomimetic that mimics the sequence of the serine protease. The Fmoc group on the N-terminal amino acid is used to protect against proteolytic degradation and its methyl ester group confers stability in biological fluids. The Fmoc-N-Me-Asn(Trt)-OH has been shown to have minimal effects on endogenous protein synthesis, while also being quantified with high sensitivity and specificity. This compound has been shown to inhibit protein-protein interactions by acting as a competitive inhibitor of serine proteases.</p>

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