Heterociclos com Nitrogénio (N)

<p>Applications 5-Methyl-pyrazine-2-carboxylic Acid (cas# 5521-55-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate<br></p>

<p>Applications 4-(Difluoromethoxy)piperidine (cas# 1147107-39-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 2-(2-Aminobenzoyl)pyridine, is an intermediate used for the synthesis of various Quinoline derivatives. It can also be used in the synthesis of the antitumoral agent batracylin and related isoindolo[1,2-b]quinazolin-12(10H)-ones.<br>References Chia-Chung, Ch., et al.: Organic Reactions, 28 (1982); Martinez-Viturro, C. M., et al.: Tetrahedron Letters, 48, 1023 (2007);<br></p>

<p>Applications 4-(1H-1,2,3-benzotriazol-1-yl)pyrimidin-2-amine (cas# 1542059-06-2) is a useful research chemical.<br></p>

<p>Applications 2,4-Dichloropyridine is a versatile reactant used in the preparation of host materials for light-emitting diodes with heterocyclic cores. Also used in the preparation of sulfonylated pyridines, pyrazine and quinoline via aromatic nucleophilic substitution of azines with sodium sulfinates.<br>References Su, S., et al.: Chem. Mater., 23, 274 (2011); Maloney, K., et al.: Org. Lett., 13, 102 (2011);<br></p>

<p>Applications 5-Amino-1-phenylpyrazole is a reagent that is used in the synthesis of sulfaphenazole(S689020) derivatives as inhibitors and tools for comparing active sites of human liver cytochromes P 450 2C subfamily.<br>References Vestergren, A.L.S. et al.: Mol. Biol. Rep., 39, 6867 (2012); Huang, C. et al.: Amer. J. Phys., 298, H570 (2010); Ha-Douong, N., et al.: J. Med. Chem., 44, 3622 (2001);<br></p>

<p>Applications 2-Fluoro-5-pyrimidinol is a structural analog of 2-Methyl-5-pyrimidinol (M326115); a pyrimidinyl derivative used as an insecticide intermediate.<br>References Cox, R., et al.: J. Phys. Chem., 72, 1646 (1968); Norton, R., et al.: Mol. Cell Biochem., 12, 103 (1976); Imai, E., et al.: Science, 283, 831 (1999)<br></p>

<p>Applications 3-(1H-Tetrazol-5-yl)benzoic Acid is a useful reactant in organic synthesis.<br>References Ouellette, Wayne, et al.: Inorganica Chimica Acta, 391, 36-43 (2012);Ramachandran, Sreekanth A., et al.: Bioorg. &amp; Med. Chem. Let., 27(10), 2153-2160 (2017)<br></p>

<p>Applications 4-(Piperazinomethyl)benzoic Acid, Dihydrochloride (cas# 86620-70-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-(Aminosulphonyl)-1-methyl-1H-pyrrole-2-carboxylic acid (cas# 306936-62-9) is a useful research chemical.<br></p>

<p>Applications 3-Bromopicolinic Acid Sodium Salt (cas# 1189933-55-8) is a compound useful in organic synthesis.<br>References See mercaptopicolinic acid file<br></p>

<p>Applications 2-PHENYLPIPERAZINE 2HCL (cas# 872139-22-5) is a useful research chemical.<br></p>

<p>Applications Tetrazolo[1,5-a]pyridin-7-amine is a chemical intermediate for the synthesis of pharmaceutical goods.<br></p>

<p>Applications 5-Pyridin-4-yl-1H-indazole (cas# 885272-55-9) is a useful research chemical.<br></p>

<p>Applications (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxy-benzeneacetic Acid is an intermediate used to prepare Cephalosporin derivatives with activities against both Gram-positive and Gram-negative bacteria.<br>References Albrecht, H., et al.: J. Med. Chem., 37, 400 (1994)<br></p>

<p>Applications 3-(2-Chloroethyl)benzimidazolidin-2-one (cas# 52548-84-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used to prepare biosynthetic polymer surfactants designed for shear-stable endothelialization.<br>References Schaefer, A., et al.: J. Bacteriol., 178, 2897 (1996), Ruegsegger, M., et al.: J. Biomed. Mat. Res., 56, 159 (2001), Abdu-Allah, H., et al.: J. Med. Chem., 51, 6665 (2008), Georgiades, S., et al.: Bioorg. Med. Chem. Lett., 18, 3117 (2008),<br></p>

<p>Applications 2-(tert-Butylamino)-4-chloro-6-cyclopropylamino-1,3,5-triazine (cas# 26737-71-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-(2,3-Difluorophenyl)picolinic acid<br></p>

<p>Applications Diethyl Pyridine-2,3-dicarboxylate is a useful reagent in preparation of herbicides.<br>References Doehner, R.: Eur. Pat. Appl. (1988), EP 254951 A2 19880203.<br></p>

<p>Applications An intermediate of Rosuvastatin (R700500).<br></p>

<p>Applications 2-Amino-3-bromopyrazine-5-carboxylic Acid (cas# 887352-34-3) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(2-(2-Nitro-1H-imidazol-1-yl)ethyl)acrylamide is a useful synthesis intermediate.<br></p>

<p>Applications 4-Pyrazoleboronic Acid Pinacol Ester is used in the preparation of Rho kinase (ROCK) inhibitors as wella s other biologically active compounds.<br>References Chowdhury, S. et al.: Bioorg. Med. Chem. Lett., 21, 7107 (2011);<br></p>

<p>Applications 4-Chloro-6-phenylpyrimidine (cas# 3435-26-5) is a useful research chemical.<br></p>

<p>Applications 5-(4-methylphenyl)imidazolidine-2,4-dione (cas# 69489-37-8) is a useful research chemical.<br></p>

<p>Applications 2,4-Dichloro-5-trifluoromethylpyrimidine is a reactant in the preparation of pyrimidine derivatives as inhibitors of gene ALK protein Kinase phosphorylating kinase and as cell proliferation inhibitors.<br>References Yang, E.H., et. al.: Bull. Korean Chem. Soc., 34, 3129 (2013)<br></p>

<p>Applications 2-(3,5-Dichlorophenyl)-imidazo[1,2-a]pyridine is derived from Ethyl Bromoacetate (E900140), which is used in the synthesis of metabolites of carcinogenic PAHs. Also it is used in the preparation of steroidal antiestrogens through cyclic condensation. A reactant in the preparation of antimicrobial and antioxidant coumarinyloxymethyl-thiadiazolone.<br>References Wu, A. et al.: Tetrahedron, 68, 7217 (2012); Clark, E. et al.: J. Med. Chem., 20, 1096 (1977); Al-Amiery, A. et al.: Chem. Nat. Comp., 48, 950 (2013);<br></p>