Heterociclos com Nitrogénio (N)

<p>Please enquire for more information about 2-Iodo-5-methylpyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Chloro-4,6-difluoro-pyridine is an electrophilic compound that can react with nucleophiles to form covalent bonds. This reaction is known as nucleophilic substitution and it can be used in the synthesis of organic compounds. The diisopropylamide of lithium is a popular reagent for this purpose because it is inexpensive, highly reactive, and easily purified by distillation. In particular, 2-chloro-4,6-difluoro-pyridine reacts quantitatively with lithium diisopropylamide to form 4-(2-chloro-4,6-difluoro)pyrimidin-2(1H)-ones in tetrahydrofuran.</p>

<p>3-Chloro-2-nitropyridine is a chemical compound that has been shown to have anticancer activity. It is a structural analog of the nucleophilic piperazine, which can react with hydrogen fluoride in an electrophilic substitution reaction to form 3-chloro-2-nitropyridine oxide. The anticancer activity of this compound may be due to its ability to inhibit the growth of tumor cells by binding to the d4 receptor, inhibiting the production of inflammatory cytokines and growth factors. 3-Chloro-2-nitropyridine has also been shown to have antiinflammatory activities, which may be due to its inhibition of nitric oxide synthesis and 5'-lipoxygenase.</p>

<p>Please enquire for more information about a,a-Diphenyl-2-pyridinemethanol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 6-methyl-2-thioxo-4-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(2-Chloroethyl)piperidine hydrochloride is a chemical compound that has photochemical properties. It is used as an amine and in the synthesis of other chemicals. The crystal structure of 1-(2-Chloroethyl)piperidine hydrochloride has been determined by X-ray crystallography. It also has antibacterial activity and inhibits the growth of bacteria by binding to single-stranded DNA, which prevents DNA replication. 1-(2-Chloroethyl)piperidine hydrochloride binds to DNA with tetradentate coordination, forming a stable complex which does not allow the DNA polymerase to bind to the single strand. 1-(2-Chloroethyl)piperidine hydrochloride can be detected using mass spectrometry and nuclear magnetic resonance spectra.</p>

<p>2-Hydroxy-4-methylpyrimidine is a heterocyclic compound that is used in the synthesis of other heterocycles. It is prepared by the reaction of methylbenzene and nitrous acid, followed by hydrolysis to form an imine. This compound has been synthesized with various substituents at different positions on the ring and also as a series of homologues. The 2-hydroxy-4-methylpyrimidine molecule has four nitroso groups, which are substituted with methyl groups. X-ray crystallography studies have shown that the molecule can exist in two different forms: one with the methyl groups pointing "homotopically" towards each other and the other with them directed "heterotopically."</p>

<p>Please enquire for more information about 2-Hydroxypyrimidine-5-boronicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-butyl (2S)-2-Methyl-4-oxopiperidine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Amino-5-fluoropyridine is a chiral amino acid that can be synthesized from butyronitrile and fluorine in the presence of an organocatalyst. The synthesis can be carried out with either a biodegradable or non-biodegradable catalyst. 3-Amino-5-fluoropyridine can be used as a precursor to prepare medicines such as fluoroquinolones, which are antibiotics that inhibit bacterial growth by binding to DNA-dependent RNA polymerase and preventing transcription and replication. Fluoroquinolones are also potent anti-inflammatory agents and have been shown to reduce inflammation in animal models of asthma, arthritis, and colitis. 3-Amino-5-fluoropyridine can be synthesized from nitro compounds with aluminium mediated reactions. Nitro compounds are toxic substances that have been used in explosives or as herbicides.</p>

<p>Please enquire for more information about Cinidon ethyl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(3-Chlorophenyl)piperazine dihydrochloride is a serotonin antagonist that has been shown to cause an increase in cortisol levels. It is also a serotonergic agent, which may be related to its antidepressant activity. 1-(3-Chlorophenyl)piperazine dihydrochloride has been shown to have a matrix effect on the brain and can be used as a drug for treating primary pulmonary hypertension. It can also induce behavioral changes and stimulate ovarian activity. The compound 1-(3-Chlorophenyl)piperazine dihydrochloride is an antagonist of 5-HT2C receptors, and it has no affinity for the 5-HT2A receptor.</p>

<p>Please enquire for more information about 2-Bromo-5,6-dihydro-8h-imidazo[1,2-a]pyrazine-7-carboxylic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Methyl-5-(tributylstannyl)pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Phenyl-4-carbethoxy piperidineHCl is a germanium compound that can be used as a diagnostic agent to detect the presence of magnesium in the blood. It has been shown to bind to acidic and basic sites on the brain, regulating the functions of these regions. The drug has also been shown to have analgesic properties, as it activates opioid receptors in the brain. 4-Phenyl-4-carbethoxy piperidineHCl binds with high affinity to meperidine and naloxone, which are opioid receptor agonists. It is also able to bind to pentazocine, an opioid receptor antagonist. This drug is not active against molybdenum or thebaine.</p>

<p>Please enquire for more information about 4-Chloro-3-iodopyridin-2-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Benzyl-4-phenylpiperazine is a type of phenylpiperazine that has hydroxy, phenyl ring, alkylthio, naphthyl and dopamine. It is an agonist for the D2 receptor and a specific ligand for the serotonin 5HT1A receptor. 1-Benzyl-4-phenylpiperazine has been shown to be effective in treating depression and psychotic depression. This drug can also be used as a substance in research on the neuropsychology of depression.</p>

<p>Piperidinium acetate is a photochemical agent that has been used in the photochemical oxidation of organic compounds. It is also used as a catalyst for the oxidative coupling of piperidinium salts with sodium salts to form piperidine. Piperidinium acetate can be used for the treatment of metabolic disorders, such as lactic acidosis and hyperglycemia, and autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. This compound is also known to cause allergic symptoms and anhydrous sodium may be generated in the process.</p>

<p>Please enquire for more information about 3-Bromo-2-(bromomethyl)pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Imidazole is a highly polar aromatic compound with two annular nitrogen atoms. Imidazole is widely used in the affinity purification of proteins with polyhistidine tags (His-Tag). In the protein purification process, imidazole is used for the elution of His-Tag-fused recombinant proteins from a metal-immobilised resins. In the elution buffers, imidazole is typically used in the 50 – 500 mM concentration range (Bornhorst and Falke, 2000).</p>

<p>Please enquire for more information about 1-Boc-4-imidazol-2-yl-piperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid is an inhibitor of the enzyme histamine N-methyltransferase (HNMT), which is responsible for the synthesis of histamine. The inhibition of HNMT leads to a decrease in histamine levels and therefore has been used as a treatment for chronic prostatitis, lacrimal gland, and energy efficiency. Histamine N-methyltransferase also participates in the regulation of apoptosis by methylating proapoptotic proteins like Bax, so inhibition can lead to an increase in apoptosis. This chemical is also able to bind with chloride ions and form diphenyl ethers through a reaction solution, which are known to have anticancer properties.</p>

<p>2-Bromo-6-fluoropyridine is a versatile building block that can be used to create a range of compounds. It is a useful intermediate and can be applied in the synthesis of high quality reagents, speciality chemicals, and complex compounds. It has been used as a reaction component in the synthesis of 2-(2-bromoethoxy)pyridine and 2-bromopyridine. This compound has CAS No. 144100-07-2, which makes it an important research chemical.</p>

<p>2-(Tributylstannyl)pyrimidine is a synthetic heterocycle that has antibacterial activity. It is a guanine analog that binds to the ribonucleic acid (RNA) of bacterial cells and inhibits protein synthesis by attacking the 4-chloropyrimidine moiety of nucleoside monophosphates. 2-(Tributylstannyl) pyrimidine also has antiviral properties and acts as an inhibitor of vitamin B1, which is required for the synthesis of DNA. This drug can be used in the treatment of sulfamethoxazole-resistant infections caused by bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa.<br>2-(Tributylstannyl)pyrimidine is effective at inhibiting the growth of bacteria due to its ability to form an ion pair with chloride ions. This property makes it highly reactive for transmetall</p>

<p>Fidovirsen is a nucleoside analogue that is an inhibitor of the NS3 protease of hepatitis C virus (HCV). Fidovirsen binds to the active site of the NS3 protease and prevents cleavage at the NS3/4A interface, thus inhibiting viral replication. It has been shown to be effective in clinical studies involving human liver samples. Fidovirsen has also been shown to have antiviral activity against other RNA viruses, including HIV-1 and influenza A virus. Fidovirsen has a low toxicity profile and does not exhibit cross-resistance with other antiviral drugs. The drug is being developed as a potential therapy for chronic HCV infection.</p>

<p>Please enquire for more information about N-Boc-amino-(4-N-fmoc-piperidinyl)carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1H-Pyrrolo[2,3-b]pyridin-5-ylamine is a heterocycle that can be synthesized by cyclization of pyrrole with an alkyne. The microwave irradiation of the reaction mixture leads to selective formation of 1-(2-hydroxyphenyl)pyrrolo[2,3-b]pyridine. This heterocycle can be used in the synthesis of other heterocycles and pharmaceuticals.</p>

<p>1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride is an antidepressant that belongs to the class of nefazodone. It is a prodrug, which is hydrolyzed to nefazodone in the liver. It has been shown to have a high affinity for serotonin receptors and as such may be useful for the treatment of depression. 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine Hydrochloride also has anticonvulsant properties, which may be due to its inhibition of neuronal excitability by blocking sodium channels in the brain.</p>

<p>Piperazine monohydrochloride is a white crystalline powder that is soluble in water and ethanol. It has a molecular weight of 208.23 and a melting point of 117-119°C. Piperazine monohydrochloride exhibits anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Please enquire for more information about 1-(4-Methoxy-pyridin-2-yl)-ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about {2-[(4-Phenylpiperazin-1-yl)carbonyl]phenyl}amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-4-(3-carboxymethyl-2-keto-one-benzimidazolyl)piperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Apixaban-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about trans-1-Boc-4-amino-piperidine-3-carboxylic acid ethyl ester hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-[4-(4-bromophenyl)piperazin-1-yl]ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,6-Dihydro-4-(tributylstannyl)-1(2H)-pyridinecarboxylic acid t-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-4-(4-fluorophenyl)-piperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Iodo-2-methoxypyridine-3-carboxaldehyde is a disubstituted compound that has insulin-like properties. It inhibits the activity of the insulin receptor, which may contribute to its insulin-like growth factor effects. This inhibitor also targets the protein kinase, which is responsible for the response of cells to insulin. 4-Iodo-2-methoxypyridine 3 carboxaldehyde has been shown to inhibit IGF1R and malonate ion, and it may have potential as an oral treatment for diabetes.</p>

<p>The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.</p>

<p>3-Nitropyridine is a nitro compound that is used in the preparation of pharmaceuticals. It has been shown to have an inhibitory effect on HIV and other viruses, which may be due to its ability to react with nucleophilic groups. 3-Nitropyridine has also been shown to have an inhibitory effect on the human immunodeficiency virus (HIV) by reacting with the acidic group of the virus. This reaction prevents the virus from binding to cells and entering them. 3-Nitropyridine is also used as a solvent for organic reactions.</p>

<p>4'-Amino-2,2':6',2''-terpyridine is a versatile chemical building block that can be used in the synthesis of complex compounds. It is a high quality reagent and useful intermediate for the production of speciality chemicals. 4'-Amino-2,2':6',2''-terpyridine can also be used as a reaction component or scaffold to produce other compounds. CAS No. 193944-66-0</p>

<p>Please enquire for more information about 1-(Benzyloxy)-6-oxo-1,6-dihydropyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Bromomethyl-4'-methyl-2,2'-bipyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-(Piperidine-4-carbonyl)piperidin-4-one hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,3-Dichloro-5-nitropyridine (2,3-DNP) is an antidiabetic drug that has been shown to improve insulin sensitivity in animals. It is a sample preparation reagent that can be used to validate the use of γ-aminobutyric acid (GABA) as a linker for the immobilization of proteins on solid supports. 2,3-DNP is also used as an adipose tissue marker to study obesity and insulin resistance. This drug has been shown to increase choline levels in the liver by inhibiting its export and increasing its synthesis by phosphorylation of serine hydroxymethyltransferase. 2,3-DNP also increases fatty acid synthesis by activating acetyl coenzyme A carboxylase and inhibiting carnitine palmitoyl transferase I. 2,3-DNP has also been shown to decrease food intake and body weight gain in db/db mice</p>

<p>Please enquire for more information about 2-Methoxypyrimidine-5-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Bromo-4-pyridinecarboxylic acid is a naphthyridine derivative that is used in drug development. It is a crystalline solid that can be dissolved in organic solvents. 3-Bromo-4-pyridinecarboxylic acid has been shown to have antiinflammatory properties and can be used as an oxidant. 3-Bromo-4-pyridinecarboxylic acid is being investigated as a receptor subtype for inflammatory diseases, and it has also been used to study the mechanism of chronic inflammatory diseases.</p>

<p>5-Amino-2-chloropyridine-4-carboxylic acid is a potent tyrosine kinase inhibitor. It inhibits the activation of EGFR, which may be due to its binding to the ATP-binding pocket in EGFR. 5-Amino-2-chloropyridine-4-carboxylic acid has been shown to inhibit cancer cell growth and induce apoptosis in vitro. This drug has also been shown to have potent anticancer activity in vivo, as well as inhibitory effect on tumor growth in xenograft models of human cancer cells. In addition, it inhibits the production of formamidine acetate, a precursor for histamine synthesis. 5-Amino-2-chloropyridine-4-carboxylic acid binds to formamide and formamidine acetate with high affinity and therefore inhibits histamine synthesis.</p>

<p>8-Bromo-imidazo[1,2-a]pyridine is a neutralizing agent that can be used in the synthesis of succinimide. It reacts with chloroacetaldehyde to yield the imidate ester. This reaction is catalyzed by alkali and requires filtration to remove the bromine and any other impurities. The reaction generates heat, so it must be performed in a well-ventilated area.</p>