Hidrazinas

Applications Methyl 2-benzylhydrazinecarboxylate is an intermediate for the synthesis of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro.
References Kotzki, S. et al.: J. Pharm. Exp. Ther., 346, 424 (2013); Selwood, D> et al.: J. Med. CHem., 44, 78 (2001)

3-Chlorophenylhydrazine sulphate is a chemical compound that is made by the reaction of 3-chlorophenol and hydrazine. It has been shown to be stable when mixed with other compounds, such as acetone. 3-Chlorophenylhydrazine sulphate has a reaction time of one hour when it is reacted with sodium hydrogen sulfate and zinc powder in a liquid chromatography column. The final product is detected using chromatography detection, which can detect the presence of sulfates. This chemical compound can be used to make other chemicals, such as thiosulfate or hydrochloric acid.

4-Methylphenyl hydrazine hydrochloride is a chemical compound that has been shown to be an effective treatment for lung tumors. It has been shown to inhibit tumorigenesis in animal models by the inhibition of angiogenesis and tumor growth. This drug is administered as a subcutaneous injection and can cause hemorrhaging, inflammation, and necrosis at the injection site. 4-Methylphenyl hydrazine hydrochloride has also been postulated to have anti-tumorigenic properties in animals.
4-Methylphenyl hydrazine hydrochloride inhibits the production of adenomas and adenocarcinomas in rats when given orally or intragastrically, but not when given intravenously.