Building Blocks

Applications 1,6-Dibromohexane-d12 (CAS# 169397-96-0) is a useful isotopically labeled research compound.

Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.
References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)

Applications trans-1,4-Dibromo-2-butene-d6 (CAS# 118886-18-3) is a useful isotopically labeled research compound.

Stability Light Sensitive
Applications (2E)-1,4-Dibromo-2-butene, is used as a reagent in the preparation of diaminoalkenes though copper-mediated diamination reaction.
References Martinez, C., et al.: Eur. J. Org Chem., 2014, 2017 (2014)

Applications 2,5-Dibromothiophene (cas# 3141-27-3) is a compound useful in organic synthesis.

Applications 3,5-Dibromopyridine-d3 (CAS# 1219799-05-9) is a useful isotopically labeled research compound.

Applications Inhibitor of enzyme.

Applications Used in the preparation of indole cPLA2α inhibitors.
References McKew, J. et al.; J. Med. Chem. 51, 3388 (2008);

Applications 2,6-Dibromo-4-cyanophenyl Heptanoate-d13 is a useful isotopically labeled compound

Applications 3,6-Dibromo-9H-carbazole is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.
References Naidoo, J., et al.: Tetrahedron Lett., 54, 4429 (2013)

Applications 1,4-Dibromobutane-1,1,4,4-d4 (CAS# 36684-45-4) is a useful isotopically labeled research compound.

Applications 1,2-Dibromobenzene-d4 (CAS# 1643577-34-7) is a useful isotopically labeled research compound.

Applications 2,4'-Dibromoacetophenone-2-13C (CAS# 335081-05-5) is a useful isotopically labeled research compound.

Applications Cyclopentene-d8 (CAS# 6611-46-7) is a useful isotopically labeled research compound.

Applications DL-Lysine-3,3,4,4,5,5,6,6-d8 2HCl (CAS# 284664-87-5) is a useful isotopically labeled research compound.

Applications DL-Lysine-2-15N 2HCl (CAS# 2747-89-9) is a useful isotopically labeled research compound. This compound can be used for spectrophotometric analysis to determine the mechanism of electron-capture-induced dissociation of various peptides.
References Holm, A., et.al., J. Phy. Chem.A.,111,9641-9643,(2007); Nakamura, A. Nippon Kagaku Zasshi,86,500-505,(1965);

Applications DL-Lysine-4,4,5,5-d4 2HCl (CAS# 284664-88-6) is a useful isotopically labeled research compound.

Applications N,N'-Dibenzylethylene-d4-diamine (CAS# 1219795-20-6) is a useful isotopically labeled research compound.

Applications Cyclopentanone-d8 (CAS# 4477-17-2) is a useful isotopically labeled research compound.

Applications Dibenzyl Malonate is a synthetic intermediate. It is used in the synthesis of matrix metalloproteinase inhibitor. It can also be used to prepare 2-pyridones with bactericidal activities.
References Hirayama, R., et al.: Bioorg. Med. Chem., 5, 765 (1997); Li, Q., et al.: J. Med. Chem., 39, 3070 (1996)

Applications Cyclopentanecarboxylic Acid is an aliphatic cycloalkyl carboxylic acid used in the preparation of amino acids and other biologically active compounds. Cyclopentanecarboxylic Acid was shown to have plant growth regulating activity.
References Dimitrova, T. et al.: Dok. Bulg. Akad. Nauk., 50, 103 (1997); Hasegawa, M. et al.: Tetrahedron, 56, 10153 (2000);

Applications 2-Cyclopenten-1-one is a chemical reagent used in the synthesis of LY354740, an important glutamate receptor agonist with anticonvulsant and anxiolytic properties. Also used in the synthesis of Armillarivin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Monn, J. et al.: J. Med. Chem., 40, 528 (1997); Schwartz, B. et al.: 15, 1934 (2013);

Applications Cyclopropylmethanol-d3, is a labeled analogue of Cyclopropylmethanol (C988605), which is used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);

Applications 1,3-Propane-2,2-d2-diamine 2HCl (CAS# 352438-79-0) is a useful isotopically labeled research compound.

Applications Cyclopropyl-2,2,3,3-d4-methyl-d2 Alcohol (CAS# 1219805-67-0) is a useful isotopically labeled research compound.

Applications Dibenzosuberenol is an intermediate in the synthesis of 5H-Dibenzo[a,d]cycloheptene which itself was used in the synthesis of cyclotribenzylenes. Also functions as a calmodulin inhibitor affecting various crucial cellular processes.
References Schmuck, C. et al.: Synth., 5, 655 (2002); Lavoie, P.. et al.: J. Neurobio., 17, 681 (1986);

Applications Cyclopropylmethyl-d2 Alcohol (CAS# 90568-07-3) is a useful isotopically labeled research compound.

Applications Dibenzo[b,d]thiophene-4-boronic acid

Applications A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perich, J.W., et al.: Synthesis, 142 (1988), Wong, C-H., et al.: J. Am. Chem. Soc., 115, 2260 (1993)

Applications 1,1-Cyclopropane-2,2,3,3-d4-dicarboxylic Acid (CAS# 136503-99-6) is a useful isotopically labeled research compound.

Applications Bis(3-aminopropyl-d6)amine (CAS# 1219805-55-6) is a useful isotopically labeled research compound.

Applications 1,3-Propane-2,2-d2-diamine (CAS# 352438-78-9) is a useful isotopically labeled research compound.

Applications 1,3-Propane-1,1,3,3-d4-diamine (CAS# 347840-13-5) is a useful isotopically labeled research compound.

Applications 1,3-Diamino-2-propanol is a reagent used in the quantitative fluorescent detection of pyrophosphate with quinolin-ligated dinuclear zinc complexes.
References Mikata, Y., et al.: Inorg. Chem., 52, 10223 (2013)

Applications Cypionic Acid, can be used as an organic building blocks in the synthesis of variety of pharmaceutical compound. It is used for the synthesis of Testosterone Cypionate (T155100).
References Rabkin, J.G. et al.: J. Clin. Psychopharmacol., 19, 19 (1999);

Applications Cyclopropyl Methyl Ketone is a chemical reagents used in the synthesis of PDE4 inhibitors. Also used in the synthesis of α-trifluoromethyl-amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrer, M. et al.: Tetrahedron Lett., 54, 4821 (2013); Radchenko, D. et al.: Tetrahedron Lett., 54, 1897 (2013);

Applications 5,6-Diamino-2-hydroxybenzimidazole (cas# 55621-49-3) is a compound useful in organic synthesis.

Applications Cyclopropyl-1-d1 Methyl-d3 Ketone (CAS# 95249-93-7) is a useful isotopically labeled research compound.

Applications Cyclopropyl-2,2,3,3-d4 Methyl Ketone (CAS# 350818-63-2) is a useful isotopically labeled research compound.

Applications Labelled 2,4-Diaminobutyric Acid. 2,4-Diaminobutyric Acid is a pharmacological tool and potential chiral building block. 2,4-Diaminobutyric Acid is also used as an internal standard for amino acid analysis. 2,4-Diaminobutyric Acid is also found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity in vitro and in vivo against mouse fibrosarcoma cells.
References Riordan, J.F. et al.: Methods Enzymol., 47, 31 (1977); Beart, P.M. et al.: Neurscience Lett., 5, 193 (1977); Ronquist, G. et al.: J. Cancer Res. Clin. Oncol., 96, 259 (1980); Solladie-Cavallo, A. et al.: Tetrahedron Lett., 30, 6011 (1989);

Applications Cyclopropyl Methyl Ketone-d8 (CAS# 1219799-33-3) is a useful isotopically labeled research compound.

Applications 1,2-Cyclohexane-d10-diamine (cis/trans mixture) (CAS# 2120097-66-5) is a useful isotopically labeled research compound.

Stability Store in freezer at -20°C
Applications A synthetic intermediate

Stability Volatile
Applications Cyclopopylamines can inactivate major human drug-metabolizing cytochromes P450 enzymes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shaffer C., et al.: J. Am. Chem. Soc., 123, 8502 (2001); Polasek, T., et al.: Brit. J. Clin. Pharmaco., 61, 570 (2006)

Applications 3-Chloro-4-Fluoroiodobenzene (cas# 156150-67-3) is a useful research chemical.

Applications (±)-trans-1,2-Diaminocyclohexane is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, J. J., et al.: Bioorg. Med. Chem. Lett., 20, 306 (2010)

Stability Light and Moisture sensitive
Applications (Diacetoxyiodo)benzene is a hypervalent iodine reagent that is used in conjunction with catalytic amount of sodium azide in acetonitrile, which enables oxidative decarboxylation of 2-aryl carboxylic acid into the corresponding aldehydes, ketones and nitriles.
References Telvekar, V.N., et al.: Synlett., 2778 (2012); Liu, W.B., et al.: Beilstein. J. Org. Chem., 8, 244 (2012);

Applications (1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP
References Kündig, E., et al.: Helv. Chim. Acta, 77, 421 (1994); Aramoto, H., et al.: J. Org. Chem., 74, 628 (2009)

Applications 4-Cyano-4'-n-pentyl-d11-biphenyl (CAS# 57078-20-3) is a useful isotopically labeled research compound.

Applications Cyclopentylamine is a useful synthetic intermediate. It was used to prepare chiral N-aminoacyl pyrrolidines and (adamantylamino)acetamides as selective and orally bioavailable dipeptidyl peptidase IV inhibitors with antihyperglycemic properties. It is also a reagent used to prepare dipeptidyl peptidase IV inhibitors as potent anti-diabetic agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Villhauer, E., et al.: J. Med. Chem., 46, 2774 (2003); Ahn, J., et al.: Bioorg. Med. Chem. Lett., 14, 4461 (2004)

Applications 3,5-Dichloroiodobenzene is used as a glycolate oxidase inhibitors.
References Wang, Bing. et al., PCT Int. Appl. 737 pp.(2019)

Stability Volatile
Applications Cyclopropanecarboxaldehyde is a reagent in the preparation of N-alkylphenylalaninamides of pyridinylphenyl- and oxobipyridinylamines as human GPR 142 agonists for potential use as anti-diabetic agents and the cytochrome P 450 inhibition.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lizarzaburu, M., et al.: Bioorg. Med. Chem. Lett, 22, 5942 (2012)

Applications 2,2-Difluoromalonamide is a useful reagent for the synthesis of fluorine-containing endothiopeptide analogs.
References Pikun, N. V., et al.: ARKIVOC (Gainesville, FL, US), 36-44 (2018)

Applications N1,N4-Di-p-tolylbenzene-1,4-diamine is a useful intermediate for the preparation of some chemically active substances for polymeric materials.
References Belorossova, A. G., et al.: Uchenye Zapiski Yaroslavskogo Tekhnologicheskogo Instituta, 11, 200 (1969)

Applications Cyclopropane-1-d1-carboxylic Acid (CAS# 19136-94-8) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications (±)-Mevalonolactone-4,4,5,5-d4 (CAS# 349553-98-6) is a useful isotopically labeled research compound.

Applications Cyclopropane-d5-carboxylic Acid (CAS# 1219804-09-7) is a useful isotopically labeled research compound.

Applications Cyclooctatetraene is used as a reactant in the synthesis of tricyclo[4.2.2.02,5]dec-9-ene-3,4,7,8-tetracarboxylic acid diimide, an antitumor drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Vishnuvajjala, B.R., Cradock, J.C.: J. Pharm. Sci., 75, 301 (1986)

Applications Cyclopropane-1,2,2,3,3-d5-carbonyl chloride is a useful building block for organic synthesis

Applications 1-Cyclopentenecarboxylic Acid can be used for enantioselective 1,3-dipolar cycloadditions of diazoacetates and solid-phase synthesis of substituted indolines. It can also be used to develop antagonists for A1- and A2-adenosine receptors.
References Sibi, M. P., et al.: Org Lett. 9, 1553 (2007); Nicolaou, K. C., et al.: J. Am. Chem. Soc. 122, 2966 (2000); Jacobson, K. A., et al.: Biochem. Pharmacol. 37, 3653 (1988)

Applications DL-Leucine-d7 (iso-propyl-d7) (CAS# 259225-40-6) is a useful isotopically labeled research compound.

Applications p-(Dimethyl-d6-amino)nitrosobenzene is labelled p-(Dimethylamino)nitrosobenzene (D2907600 which is an intermediate in the synthesis of Meldola Blue (M215120), a biosensor for the measurement of lactate in serum.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Vinothkumar, S.P., et al.: J. Pharma. Res., 3, 1371 (2010); Huang, R., et al.: Chem. Res. Toxicol., 21, 659 (2008);

Applications Cyclohexane-d11 (CAS# 1520-59-8) is a useful isotopically labeled research compound.

Applications 2'-Deoxyuridine-5,6-d2 (CAS# 40632-23-3) is a useful isotopically labeled research compound.

Applications Cyclohexanecarboxylic-1-d1 Acid (CAS# 933-37-9) is a useful isotopically labeled research compound.

Applications Cyclohexylacetic acid

Applications Cyclohexyl phenyl ketone is a useful research chemical in organic synthesis.
References Yang, Tonghao, et al.: Org. Let., 20(7), 1875-1879 (2018);Jarava-Barrera, Carlos, et al.: Chem. - A Euro. J., 23(69), 17478-17481 (2017)

Applications 2-Cyclohexylethanol is a useful building block, and has recently been used in a green preparation of oxidative esterification of primary alcohols.
References Reddy, N.; et al.: Synth. Commun., 48, 1663 (2018).

Applications 2,4-DIAMINOPTERIDINE-6-CARBOXYLIC ACID (cas# 716-74-5) is a useful research chemical.

Applications 2-Cyclohexen-1-Ol (cas# 822-67-3) is a useful research chemical.

Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).
References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);

Applications 4-(Cyclohex-1-en-1-yl)morpholine (cas# 670-80-4) is a useful research chemical.

Applications 2-Cyano-6-Hydroxybenzothiazole (cas# 939-69-5) is a useful research chemical.

Applications 1-Formylcyclohexanecarboxylic Acid Methyl Ester (cas# 84393-05-5) is a useful research chemical.

Applications 1,4-Dibromopentane (CAS# 626-87-9) is a useful research chemical compound.