Building Blocks

Applications 1-Bromo-3-chloro-5-fluorobenzene-d3 (CAS# 1219805-00-1) is a useful isotopically labeled research compound.

Applications 4-Bromophenetole is a non-irritant used to verify ocular irritability tests.
References Abraham, M., et al.: Toxicol. Sci., 76, 384 (2003); Cruz-Monteagudo, M., et al.: B. Math. Bio., 68, 1555 (2006)

Applications N-Tosylpyrrole (cas# 17639-64-4) is a compound useful in organic synthesis.

Applications 2-oxo-2,3-dihydrobenzo[d]oxazol-6-ylboronic acid pinacol ester (cas# 1105710-32-4) is a useful research chemical.

Applications o-Nitrophenylsulfonyl Chloride is used in the synthesis of renin inhibitors and also anticonvulsants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harish, K. et al.: Lett. Drug Des. Disc., 10, 783 (2013); Michida, M. et al.: Org. Proc. Res. Dev., 17, 1430 (2013);

Applications 2,4-Dichlorotoluene-3,5,6-d3 (CAS# 1398065-47-8) is a useful isotopically labeled research compound.

Applications 4-Bromo-1-butyne is used in the regioselective preparation and CDC25 phosphatase inhibition activity SAR of triazolobenzylidene-thiazolopyrimidines via parallel click chemistry between azidobenzylidene-thiazolopyrimidines and alkynes
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Duval, R., et al.: J. Comb. Chem., 11, 947 (2009)

Applications 2-Cyano-6-Hydroxybenzothiazole (cas# 939-69-5) is a useful research chemical.

Applications N,N-Dimethylacetamide-2,2,2-d3 (CAS# 20255-66-7) is a useful isotopically labeled research compound.

Applications 4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perez, D. et al.; J. Med. Chem. 54, 4042 (2011)

Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.

Applications 2-Methoxycarbonylphenylboronic acid

Applications N,N-Dimethylaniline-d3 (N-methyl-d3) (CAS# 88889-00-3) is a useful isotopically labeled research compound.

Applications 4-PICOLINE-N-OXIDE (cas# 1003-67-4) is a useful research chemical.

Applications Methyl Benzoate-d8 (CAS# 91929-46-3) is a useful isotopically labeled research compound.

Applications 4-PIPERAZIN-1-YL-QUINOLINE DIHYDROCHLORIDE (cas# 1350361-89-5) is a useful research chemical.

Applications trans-Stilbene-alpha,beta-13C2 (CAS# 153610-50-5) is a useful isotopically labeled research compound.

Applications Nefiracetam improves post-ischemia evoke-nonconvulsive seizure by altering pro-inflammatory cytokines.
References Fu, C. et al: Cell. Phys. Biochem., 37, 2023 (2015);

Applications Methyl Benzoate-2,3,4,5,6-d5 (CAS# 68661-19-8) is a useful isotopically labeled research compound.

Applications Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.
References Sun, L. et al.: Cell, 148, 213 (2012);

Applications Cyclohexyl phenyl ketone is a useful research chemical in organic synthesis.
References Yang, Tonghao, et al.: Org. Let., 20(7), 1875-1879 (2018);Jarava-Barrera, Carlos, et al.: Chem. - A Euro. J., 23(69), 17478-17481 (2017)

Applications Anteisoheneicosanoic acid-d3 is labelled Anteisoheneicosanoic acid which is used in cosmetics as it allows hair fiber to lie flat and parallel with respect to each other while its removal formed coarse tangled bundles, aligned in disorderly manner.
References Tanamachi, H., et al.: J. Cosmetic Sci., 61, 147 (2010); Breakspear, S., et al.: PMSE Preprints, 90, 276 (2004)

Applications Heptanoic Acid (D13, 98%) (cas# 130348-93-5) is a useful research chemical.

Applications 2,3-disubstituted benzaldehyde.

Applications 1,5-Dinitronaphthalene-d6 (CAS# 1219804-48-4) is a useful isotopically labeled research compound.

Applications 2-Nitropropane-1,1,1,3,3,3-d6 (CAS# 52809-86-6) is a useful isotopically labeled research compound.

Applications Cyclohexane-d11 (CAS# 1520-59-8) is a useful isotopically labeled research compound.

Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications A compound used in the models of aquatic toxicity developed (QSAR). Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis.
References Kubinyi, H., et al.: J. Med. Chem., 41, 2553 (1998), Hengstler, J., et al.: Toxicology, 220, 232 (2006),

Applications 1-Cyclopentenecarboxylic Acid can be used for enantioselective 1,3-dipolar cycloadditions of diazoacetates and solid-phase synthesis of substituted indolines. It can also be used to develop antagonists for A1- and A2-adenosine receptors.
References Sibi, M. P., et al.: Org Lett. 9, 1553 (2007); Nicolaou, K. C., et al.: J. Am. Chem. Soc. 122, 2966 (2000); Jacobson, K. A., et al.: Biochem. Pharmacol. 37, 3653 (1988)

Applications 2-Methyl-d3-3-butyn-1,1,1-d3-2-ol (CAS# 57444-27-6) is a useful isotopically labeled research compound.

Applications 1,3,5-Benzene-2,4,6-d3-tricarboxylic Acid (CAS# 62790-27-6) is a useful isotopically labeled research compound.

Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.
References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);

Applications 2-Pyridylacetic-alpha,alpha-d2 Acid-OD DCl (CAS# 1219802-51-3) is a useful isotopically labeled research compound.
Chemical Name: 2-Pyridylacetic-alpha,alpha-d2 Acid-OD DCl (CAS# 1219802-51-3) is a useful isotopically labeled research compound.

Applications 2,4,5-Tribromotoluene (cas# 3278-88-4) is a useful research chemical.

Applications (S)-(+)-4-Benzyl-3-benzyloxyacetyl-2-oxazolidinone is an oxazolidinone used as a building block in the synthesis of epothilones.
References Scheid, G. et al.: Tetrahedron., 15, 2861 (2004)

Applications 2,6-Naphthalenedicarboxylic-d6 Acid (CAS# 682321-46-6) is a useful isotopically labeled research compound.

Applications 5-Bromovaleric Acid used in the synthesis of inhibitors for aminoglycoside resistant bacteria. Also used in the preparation of sequence specific base pair mimics as topoisomerase IB inhibitors.
References Vong, K. et al.: ACS Chem. Biol., 7, 470 (2012); Vekhoff, P. et al.: Biochem., 52, 43 (2012);

Stability Air Sensitive
Applications alpha-Methyl-trans-cinnamaldehyde is a compound with antifungal activity for proteomics research use.

Applications Sodium Hexadecanoate-d31 (CAS# 467235-83-2) is a useful isotopically labeled research compound.

Applications N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE (cas# 55750-63-5) is a useful research chemical.

Stability Light Sensitive
Applications (E)-3-(Furan-2-yl)acrylaldehyde is a useful reagent in the synthesis of highly substituted tetrahydrofurans and tetrahydropyrans using double Michael addition strategy. A synthesis intermediate.
References Mondal, B., et al.: Asian J. Org. Chem., 7, 1788 (2018); Mukherjee, S., et al.: Org. Lett., 20, 2952 (2018)

Applications Sodium Hexadecanoate-16,16,16-d3 (CAS# 347841-37-6) is a useful isotopically labeled research compound.

Applications Cyclopropane-1,2,2,3,3-d5-carbonyl chloride is a useful building block for organic synthesis

Applications n-Propyl-3,3,3-d3-amine HCl (CAS# 478702-86-2) is a useful isotopically labeled research compound.

Applications 4-methyl-3-oxo-2,3-dihydro-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid (cas# 862273-50-5) is a useful research chemical.

Applications 1-Bromopentadecane-d31 (CAS# 349553-93-1) is a useful isotopically labeled research compound.

Applications Naphthalene-2,3,4,5,6,7,8-d7 (CAS# 887-68-3) is a useful isotopically labeled research compound.

Applications 2-Cyclopenten-1-one is a chemical reagent used in the synthesis of LY354740, an important glutamate receptor agonist with anticonvulsant and anxiolytic properties. Also used in the synthesis of Armillarivin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Monn, J. et al.: J. Med. Chem., 40, 528 (1997); Schwartz, B. et al.: 15, 1934 (2013);

Applications Cyclopentanecarboxylic Acid is an aliphatic cycloalkyl carboxylic acid used in the preparation of amino acids and other biologically active compounds. Cyclopentanecarboxylic Acid was shown to have plant growth regulating activity.
References Dimitrova, T. et al.: Dok. Bulg. Akad. Nauk., 50, 103 (1997); Hasegawa, M. et al.: Tetrahedron, 56, 10153 (2000);

Applications Naphthalene-1-d1 (CAS# 875-62-7) is a useful isotopically labeled research compound.

Applications (4-Methoxy-3,5-dimethylpyridin-2-yl)methanol (cas# 86604-78-6) is a useful research chemical.

Applications Fumaryl Chloride is a reagent used in the synthesis of thermosetting resins which are widely used in industrial fields.
References Kudo, K. et al.: J. App. Polym. Sci., 133 (2016);

Stability Volatile
Applications 2,5-Norbornadiene shows anti-ethylene effects on plants and inhibits polyphenol oxidase, peroxidase and phenylalanine ammonia lyase activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hu, W., et al.: J Food Sci, 3, 123-130 (2013)

Applications 5-​Bromopentyl Acetate is used to model the toxicity of haloesters on marine bacterium such as Vibrio fischeri.
References Cornin, M.T.D, et. al.: SAR QSAR Environ. Res., 11, 301 (2000)

Applications Gaboxadol is a sleep aid drug used for the treatment of chronic pain and insomnia. Gaboxadol is also known to exhibit antidepressant like properties through its agonistic activities towards GABA sites.
References Vashchinkina, E., et al.: J. Neurosci., 32, 5310 (2012); Christensen, T., et al.: Eur. Neuropsychopharmacol., 22, 751 (2012);

Applications A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perich, J.W., et al.: Synthesis, 142 (1988), Wong, C-H., et al.: J. Am. Chem. Soc., 115, 2260 (1993)

Applications exo-Norborneol (cas# 497-37-0) is a useful research chemical.

Applications Cyclopentanone-d8 (CAS# 4477-17-2) is a useful isotopically labeled research compound.

Applications N-Methyl-d3-form-d1-amide (CAS# 110505-55-0) is a useful isotopically labeled research compound.

Applications n-Octylbenzene-d22 (CAS# 1219799-28-6) is a useful isotopically labeled research compound.

Applications 1-Bromodecane-1,1,2,2-d4 (CAS# 1219805-58-9) is a useful isotopically labeled research compound.

Applications Cyclopentene-d8 (CAS# 6611-46-7) is a useful isotopically labeled research compound.