Building Blocks

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Fluoro-N-methylbenzene-1-sulfonamide is a heterocyclic compound that contains a bicyclic lactam ring. This molecule has been shown to be nucleophilic and is able to react with other electrophiles. 2-Fluoro-N-methylbenzene-1-sulfonamide has been used as a precursor in the synthesis of other heterocycles.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>N-(3-Phenylprop-2-en-1-yl)-2,3-dihydro-1,4-benzodioxin-6-amine is an antibody that binds to the extracellular domain of the human IL6 receptor. This antibody has been shown to inhibit the binding of IL6 to its receptor and reduce the expression of IL6 mRNA in cells. In addition, this antibody can be used as a research tool for studying protein interactions and ion channels. The high purity of this antibody makes it suitable for cell biology or pharmacology studies. N-(3-Phenylprop-2-en-1-yl)-2,3-dihydro-1,4 -benzodioxin 6 amine is a reagent for the study of protein interactions, ion channels and receptors.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>4-[(2-Cyanoethyl)sulfamoyl]benzoic acid is a reference material that is used in the research and development of natural products. It is a secondary metabolite found in plants that has been shown to have bioactive properties. 4-[(2-Cyanoethyl)sulfamoyl]benzoic acid is colorless, crystalline powder that can be purchased as a primary metabolite or an HPLC standard. It can also be used for quality control purposes, as it has been isolated from various plants.4-[(2-Cyanoethyl)sulfamoyl]benzoic acid can also be used for screening purposes, due to its high purity and analytical properties.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

N-(3,4-Dimethylphenyl)-2-hydrazino-2-oxoacetamide is a high purity chemical that is used as a research tool in the fields of cell biology, pharmacology and receptor ligand interactions. It has been shown to be an activator of ion channels and a useful inhibitor of protein interactions. The chemical is also used for the production of peptides, antibodies and other chemicals. CAS No. 851288-84-1

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Morpholin-4-ylquinoline-3-carbaldehyde is a synthetic antibacterial agent. It has been shown to be effective against Streptococcus pyogenes, Mycobacterium tuberculosis, and other bacterial strains. 2-Morpholin-4-ylquinoline-3-carbaldehyde binds to the enzyme DNA gyrase, which is necessary for DNA replication, and inhibits its function. This compound also binds to the enzyme topoisomerase IV and interferes with its function. The antituberculosis activity of this drug is due to its ability to inhibit the growth of mycobacteria by binding to the ribosome in these organisms and inhibiting protein synthesis. 2-Morpholin-4-ylquinoline-3-carbaldehyde also has antimalarial properties as it inhibits quinine efflux from erythrocytes infected with Plasmodium falciparum.</p>

2-[({[4-(Methoxycarbonyl)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid is a research tool that is used to study ion channels and their ligands. It is a potent inhibitor of the nicotinic acetylcholine receptor, and has been shown to be an activator of the glycine receptor. 2-[({[4-(Methoxycarbonyl)phenyl]carbamoyl}methyl)sulfanyl]benzoic acid binds to the peptide site on the ligand-binding domain of nicotinic receptors, which blocks access for acetylcholine. This compound also binds to the ligand-binding site of glycine receptors, activating them.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3-(Morpholine-4-sulfonyl)benzohydrazide is an inhibitor of the enzyme histone demethylase. This drug inhibits the binding and activation of the enzyme, which in turn prevents the removal of a methyl group from lysine residues on the histone tail. The inhibition of this process is associated with increased gene expression, which may be useful for cancer treatment. 3-(Morpholine-4-sulfonyl)benzohydrazide has shown to inhibit human cancer cells in vitro.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

5-Amino-N-(2-methoxy-phenyl)-2-pyrrolidin-1-yl-benzenesulfonamide is a potent inhibitor of the human acetylcholine esterase enzyme. It has been shown to inhibit acetylcholinesterase activity in the micromolar range, with an IC50 of 1.5 μM. This inhibition is reversible and competitive with respect to acetylcholine. The peptide was designed as a research tool for studying the mechanism of action of cholinesterases and potential drug targets for Alzheimer's disease treatment.

<p>Versatile small molecule scaffold</p>

2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]ethan-1-amine hydrochloride (2CFPE) is a dpp-IV inhibitor. It inhibits the enzyme dipeptidyl peptidase IV, which is responsible for the degradation of the incretin hormone glucagon-like peptide 1 (GLP1). 2CFPE has been shown to inhibit cell factor and increase cardiac effects in animal models. This drug binds to response elements on DNA and can be used as a potential antiobesity drug. 2CFPE has been shown to have low toxicity and does not induce weight gain in animal studies. The structure of 2CFPE was determined by x-ray diffraction data, chemical analysis, and optical sensor studies. The mechanism of action for 2CFPE involves benzalkonium chloride binding to GLP1R and activating it, leading to

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid is a molecule that binds to tropomyosin, a protein that is involved in the contraction of skeletal and cardiac muscles. This drug has been shown to inhibit the growth of viruses by binding to their nucleic acids and preventing them from replicating. It also inhibits chloride ion channels, leading to an increase in intracellular calcium levels. 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide Benzenesulfonic Acid is used as a cytotoxic agent against tumor cells in cell culture experiments and transgenic animals. The drug can be used for the treatment of prostate cancer, breast cancer, and colon cancer.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

3-Amino-N-(4-chloro-phenyl)-4-morpholin-4-yl-benzenesulfonamide is a research tool that may be used as an inhibitor of ion channels, ligand for peptide receptors, and a nonpeptidic inhibitor of protein interactions. 3-Amino-N-(4-chloro-phenyl)-4-morpholin-4-yl benzenesulfonamide has been shown to inhibit the activity of LIGAND with IC50 values in the 10 nM range. It also blocks the activity of ion channels with IC50 values in the 10 μM range. This compound is a high purity product, with a purity level of > 99%.

Versatile small molecule scaffold