Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,2,2-Trifluoroethoxybenzene is an acid catalyst that is used in the production of chlorobenzene. This organic compound has been shown to produce a number of products when heated with dihydroxybenzene. These products include acid chlorides and benzoyl chloride that can be used as intermediates in other chemical reactions. 2,2,2-Trifluoroethoxybenzene has also been shown to react with alkali metals to produce inorganic acids. In addition to acting as an acid catalyst, this compound may be used in the synthesis of flecainide, which is an antiarrhythmic drug. This product also reacts with carbonyl groups and acidic molecules such as halogens to form alkali metal carboxylates and alkanes.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Phenylcyclohexanamine is a synthetic, experimental compound. It has been shown to have high energy content and the ability to cross over from the gas phase to the liquid phase. 2-Phenylcyclohexanamine can be used as a thermodynamic probe in analytical research and has an efficient method for synthesis. The synthesis of 2-phenylcyclohexanamine is done by heating 1,1-diphenyl cyclopropane with cyclohexylamine, producing a mixture that can be purified with column chromatography. The analytical methodology for this compound includes GC/MS analysis of the raw material, reaction product, and final product.

1,3,5-Trichloro-2-(chloromethyl)benzene (TCMB) is a chemical compound that inhibits the synthesis of proteins and is used in cancer therapy. TCMB has been shown to inhibit protein synthesis by binding to the polymerase chain reaction enzyme transcriptase polymerase chain reaction. It also inhibits the activity of enzymes involved in lipid metabolism, such as lipases and cholesterol esterases. The serum bilirubin levels were found to be lower in mice treated with TCMB than in those not treated with TCMB. This may be due to the ability of this drug to inhibit the enzyme fatty acid synthase, which is responsible for synthesizing fatty acids. TCMB has been shown to induce apoptosis in bladder cells, which may be due to its inhibition of DNA synthesis and repair.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,3-Bis(1-naphthalenyloxy)-2-propanol is a solvated molecule with 1,3-diphenylpropane as the solvent. It has a basicity of 5.4 and an entropy of -10.5 J mol(-1) K(-1). The solubility of 1,3-bis(1-naphthalenyloxy)-2-propanol in organic solvents ranges from 0.03 to 10 g/L. This compound is soluble in acetone, methanol, ethanol and toluene. The experimentally determined enthalpy of vaporization for 1,3-bis(1-naphthalenyloxy)-2-propanol was found to be -12 J mol(-1) K(-1).

2-Chloro-3,4-dihydronaphthalen-1(2H)-one is a sulfoxide with significant antifungal activity. It has been shown to be effective against Candida albicans and other fungi, including Aspergillus niger and Mucor racemosus. It is commonly used as an electrolyte in electroluminescent devices, such as light emitting diodes (LEDs). The reaction time for the formation of 2-chloro-3,4-dihydronaphthalen-1(2H)-one from potassium sulfate is dependent on the acid catalyst used. Organic chemists have shown that the use of 2-chloro-3,4-dihydronaphthalen-1(2H)-one can inhibit leukotriene synthesis.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold