Building Blocks

Applications An intermediate in the manufacturing of pressor amines. The sulfate salt is used as topical vasoconstrictor.
References Zhang, L., et al.: Biochem. J., 340, 255 (1999), Miyazaki, M., et al.: J. Biol. Chem., 278, 33904 (2003), Li, C., et al.: Bioorg. Med. Chem. Lett., 19, 5214 (2009),

Applications 4-azidopyridine (cas# 39910-67-3) is a useful research chemical.

Stability Hygroscopic, Moisture Sensitive
Applications Used in the synthesis of peptides. Contains up to 10% imidazole.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pierschbacher, M., et al.: Nature, 309, 30 (1984),

Applications 4-Methyldibenzothiophene, is an alkyldibenzothiophene present in crude oil. Research concerning the biodegradation of Dibenzothiophene by different types of bacteria is a currently being carried out, as these bacteria have the ability to breakdown other harmful PAH’s as well. This may be used in removing spilled oil from marine and terrestrial environments.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Boberg, F., et al.: Erdoel & Kohle, Erdgas, Petrochemie, 47, 187 (1994); Tanaka, Y., et al.: Applied Microbiology and Biotech., 59 (2), 325 (2002); Prince, R., Spill Sci. Tech. Bulletin, 8 (2), 145 (2003);

Stability Unstable in solution
Applications Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole
References Stresser, D.M., et al.: J. Biochem. Toxicol., 10, 191 (1995), Bailey, G.S., et al.: J. Natl. Cancer Inst., 78, 931 (1987), D’Agostino et. al. Drug Metabolism and Disp. 27: 2018 (2009)

Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.
References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)

Stability Moisture Sensitive
Applications 3A-METHYLHEXAHYDROISOBENZOFURAN-1,3-DIONE (cas# 25550-51-0) is a useful research chemical.

Applications METHYL PIPERIDINE-1-CARBOXYLATE (cas# 1796-27-6) is a useful research chemical.

Impurity Fluorouracil EP Impurity D
Applications 5-Methoxyuracil (Fluorouracil EP Impurity D) is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides.
References Vorbrueggen, H. et al.: Chem. Ber., 114, 1279 (1981); Novacek, A. et al.: Coll. Czech. Chem. Comm., 32, 1045 (1967);

Stability Volatile
Applications Di-tert-butyl ether (cas# 6163-66-2) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications A sulfonate ester as potential genotoxic impurity in drug substances. It may exert genotoxic effects in bacterial and mammalian cell systems.
References Eder, E., et al.: Xenobiotica, 12, 831 (1982), Li, W., et al.: J. Chromatogr., 1046, 297 (2004), Glowienke, S., et al.: Mutat. Res., 581, 23 (2005), Colon, I., et al.: J. Pharm. Biomed. Anal., 39, 477 (2005),

Applications Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.
References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010)

Applications 4-Methylcatechol is a potent inducer of nerve growth factor (NGF) synthesis in vitro and in vivo.
References Kaechi, K., et al.: J. Pharmacol. Exp. Ther., 272, 1300 (1995); Hanaoka, Y., et al.: J. Neurol. Sci., 122, 28 (1994)

Impurity Albendazole EP Impurity G / Fenbendazole EP /Impurity B / USP Fenbendazole Related Compound B
Applications Methyl [5(6)-chlorobenzimidazole-2-yl]carbamate is an impurity for Fenbendazole (F246750), an anthelmintic (Nematodes). (Albendazole Impurity H)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),

Applications trans-Indole-3-acrylic Acid is a regent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize polyphenols.
References Madrigal-Carballo, S., et al.: Int Food Res J, 20, 2023-2034 (2013)

Applications An intermediate of Penbutolol (P220500), an antihypertensive agent.
References Janusz, J.M., et al.: J. Med. Chem., 41, 3102 (1998),

Applications Mesitoic acid can be used for its antioxidant.
References Thomas, P.S., et.al.: Medicines, 4, 1-7, (2017);

Applications 1-O-Benzylethanediol (cas# 622-08-2) is a compound useful in organic synthesis.