Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1H-Tetrazol-5-yl)phenol (HTZP) is a fluorescent probe that has been shown to have a high affinity for cancer cells. It binds to the DNA of cancer cells and emits light in the presence of hydrogen peroxide. This process generates a signal with a unique wavelength that can be detected by optical microscopy, flow cytometry, and fluorescence spectroscopy. HTZP has also been shown to bind to alkali metal ions such as Li+, K+, Na+, and Cs+. HTZP is an example of a supramolecular ligand that binds to cisplatin, which inhibits DNA replication and protein synthesis in cancer cells. The binding constants for HTZP are higher than those for cisplatin, suggesting that it may be used as an alternative treatment for cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>5-(o-Tolyl)tetrazole is a compound that can be synthesized by the reaction of tetrazole with an aldehyde. It has been shown to have high efficiency in the preparation of halides, including chlorides and bromides. 5-(o-Tolyl)tetrazole is also efficient for the synthesis of functional groups, such as methyl tetrazole, ethyl tetrazole, phenyl tetrazole, and substituted phenyl tetrazoles. The cyclic form of 5-(o-tolyl)tetrazole is obtained through irradiation or catalysis.<br>5-(o-Tolyl)tetrazole can also be used as a ligand in coordination chemistry to generate metal complexes with various metals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 4-azidobutanoate is a radiotracer that binds to the DNA of tumor cells. It has been shown to have high binding activity in xenograft models, which is mediated by the interaction between ethyl 4-azidobutanoate and nucleophilic sites on the DNA. This radiotracer also has a high specificity for tumors, with no detectable uptake in other tissues. Ethyl 4-azidobutanoate can be used as a diagnostic agent for detecting and quantifying radiation-induced damage in cells and tissues.</p>

<p>2-(Hydroxymethyl)pyridine-4-carbonitrile is a methyl ester of 4-cyanopyridine and cysteine, which are two natural amino acids. This compound has been found to be an intermediate in the biosynthesis of thiazoles. It can also be synthesized from the coupling of 2-cyanopyridines with aldehydes or ketones using metal catalysts, such as palladium or platinum. 2-(Hydroxymethyl)pyridine-4-carbonitrile was first identified in luciferin, a biomimetic compound that produces light when oxidized by an enzyme called luciferase.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Thiophene-3-carboxamide is an antibacterial agent that inhibits the growth of bacteria by binding to their ribosomes and inhibiting protein synthesis. It has been shown to be active against influenza virus, highlighting its potential as a drug for the treatment of influenza. Thiophene-3-carboxamide also has anti-tumor activities and can inhibit cancer cell growth by preventing DNA replication and RNA transcription. This drug binds to the viral neuraminidase, which is an enzyme that cleaves sialic acid from glycoproteins in the host cell membrane. This inhibits the release of progeny viruses from infected cells, thus reducing viral load.</p>

<p>Versatile small molecule scaffold</p>