Building Blocks

<p>2-(4-Hydroxy-3-methoxyphenyl)-1,3-dithiolane is a metabolite of the drug product 2-[4-(hydroxymethyl)phenyl]-1,3-dithiolane. It is used as an analytical standard for drug development and in natural product research and development. The chemical properties of 2-(4-hydroxy-3-methoxyphenyl)-1,3-dithiolane are similar to those of its parent compound, but it has a smaller molecular weight. This compound has been found to be a substrate for CYP2C9 and CYP2C19 in vitro. Metabolism studies have shown that 2-(4-hydroxy-3-methoxyphenyl)-1,3-dithiolane is not converted to the parent compound or any other metabolites when incubated with human liver microsomes at 37°C.</p>

<p>Versatile small molecule scaffold</p>

<p>Thiepan-4-one is an indole derivative that belongs to the group of unsymmetrical ketones. It is a heterocyclic compound that has been found to be an effective antibiotic against Gram-positive bacteria, such as Streptococcus pyogenes and Staphylococcus aureus. Thiepan-4-one has also shown activity against Mycobacterium tuberculosis and Mycobacterium avium complex.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 4-methylheptanoate is a volatile compound that is used as a synthetic pheromone to control populations of Nicrophorus beetles. The compound is synthesized by the reaction of ethyl ester and heptanal, mediated by an organocuprate. It has been shown that this compound has a long-distance mediated effect on the population of Nicrophorus beetles. The phylogeny of this compound was determined using gas chromatography-mass spectrometry (GC-MS) analysis, which indicated that this compound is found in many species in the genus Ethyl 4-methylheptanoate. This substance also has fatty acid esters, which have been shown to have operational and behavioral effects on these beetles.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Amino-2,3-dihydro-1,2-benzothiazole-1,1,3-trione is a nitro compound that has been shown to have toxin and sweet taste activity. 5-Amino-2,3-dihydro-1,2-benzothiazole-1,1,3-trione is used in the analysis of sweeteners in food products. It is also used as an intermediate in the synthesis of other compounds. 5AMT has been shown to be mutagenic and cytotoxic in some assays.</p>

<p>6-Amino-1,1-dioxo-1,2-benzothiazol-3-one (6ABT) is a diazo compound that has been used in the synthesis of bioconjugates. 6ABT is an intermediate for the preparation of monoclonal antibodies and as an inhibitor of carbonic anhydrase II. 6ABT has been shown to have anti-cancer properties by inhibiting proliferation and inducing apoptosis in human cancer cells. It also inhibits cell growth in human colon cancer cells and human breast cancer cells. 6ABT has been found to inhibit the diphenolase activity of beta-hexosaminidase and alpha-glucosidase, which are enzymes that break down proteins and carbohydrates respectively. This inhibition may lead to metabolic disorders such as diabetes mellitus type 2.</p>