Building Blocks

<p>5-Methylquinoline is a quinoline derivative that is used in the synthesis of other quinoline derivatives. It can be synthesized from cinnamaldehyde, which can be obtained from cinnamic acid or benzaldehyde. 5-Methylquinoline has been shown to have antioxidant properties and inhibit colorectal carcinoma cells in vitro. The compound also inhibits the growth of caco-2 cells. One isomer of 5-methylquinoline, ethenyl, has been shown to cause a shift in the spectrum of light absorbed by caco-2 cells.</p>

Versatile small molecule scaffold

4-(Trimethylsilyl)phenyl]methanamine is a pharmacological molecule that has been synthesized to have fluorine atoms. 4-(Trimethylsilyl)phenyl]methanamine is used in bioconjugate chemistry, which is the process of attaching two molecules together. In this case, the molecule attaches itself to a nucleotide. The fluorine atom helps stabilize the bond between the nucleotide and the molecule by increasing its electron affinity. This radiolabeled molecule can be used as a radioactive isotope in radiotracer studies to study how cells metabolize drugs and other agents.

1-Propyl-1H-1,3-benzodiazole is a nitro derivative of the benzimidazole compounds. It is used in the preparation of azo dyes and as a dye intermediate. 1-Propyl-1H-1,3-benzodiazole is metabolized through oxidative or reductive pathways to form reactive intermediates that bind to DNA and protein substrates. This compound also inhibits fatty acid synthesis by forming ternary complexes with enzyme acyl carrier protein (ACP) and coenzyme A (CoA). The metabolism of 1-propyl-1H-1,3-benzodiazole leads to the formation of reactive metabolites that can cause congestive heart failure in mammals.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Methyl-1,5-naphthyridine is an antitumor agent that inhibits the activity of an efflux pump in tumor cells. The drug was shown to inhibit the proliferation of a tumor cell line in vitro and inhibited tumor growth in vivo. 4-Methyl-1,5-naphthyridine also has potent synergistic effects with carbon disulfide, which is used as a chemotherapeutic agent for cancer treatment. This compound also inhibits the production of endocannabinoids and has been shown to have antidepressant and antinociceptive properties in animal models.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2-Vinylcyclopropane-1,1-dicarboxylic acid diethyl ester (VCPD) is a molecule that is synthesized by the nucleophilic attack of an alcohol on the double bond of a cyclopropane ring. VCPD is used in the production of polymers and copolymers. VCPD can be copolymerized with other monomers such as styrene, chloromethylstyrene, acrylonitrile, vinyl acetate, vinyl chloride and butadiene to produce various types of polymers. The polymerization process involves three steps: initiation, propagation and termination. Initiation takes place when persulfate is added to VCPD and water at high temperature. The polymerization process ends when there are no more VCPD molecules available for reaction or when all the monomers have been consumed during the reaction.

Versatile small molecule scaffold

<p>Methyl 2-bromo-3-hydroxypropanoate is a linear molecule that can be used to produce polymers and copolymers. This compound is polymerized with other monomers to form poly(methyl 2-bromo-3-hydroxypropanoate) (PMBH). It can also be used as a crosslinker in the production of polyurethane. Methyl 2-bromo-3-hydroxypropanoate can be made by reacting sodium carbonate, chloride, and trifluoride with methyl 3-methoxypropanoate. The reaction produces an intermediate that is then reacted with bromine gas to yield methyl 2-bromo-3-hydroxypropanoate.<br>Methyl 2-bromo-3-hydroxypropanoate is biodegradable and has been shown to have low toxicity. It has been used in a number of biomedical applications such as</p>

4-Chlorophenyl Chloroformate is a chlorinating agent that has been shown to increase intracellular levels of carbon sources. It also has been shown to selectively act on the phenyl group of histidine and amines. 4-Chlorophenyl Chloroformate can be used as a synthetic intermediate in the synthesis of other compounds, including antidiabetic agents.

2-Naphthyl chloroformate is a chemical reagent that is used to derivatize amines for chromatography. The compound reacts with the amine and forms an ester, which can be used as a chromatographic stationary phase. It has been shown that 2-naphthyl chloroformate can be used to detect serotonin in urine samples by fluorescence detection. This compound is also used in the production of ethylene diamine and citric acid. 2-Naphthyl chloroformate is not toxic and does not appear to cause any adverse effects on human health at levels up to 1,000 ppm.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>