Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 2-methyl-5-phenyl-1H-pyrrole-3-carboxylate is a serotonin analog. It has been shown to have antidepressant properties and inhibit the reuptake of serotonin by the neurotransmitter transporter. This leads to an increase in serotonin levels in the brain, which may be due to its ability to act on 5-HT2A and 5-HT2C receptors. The compound also acts as an antagonist at 5HT1A receptors, which may contribute to its antidepressant effects. In vivo activities of this drug have been confirmed using various animal models. Ethyl 2-methyl-5-phenyl-1H-pyrrole-3--carboxylate is a lead compound for other potential antidepressants with similar activity.

Ethyl 6-aminohexanoate,hydrochloride is a monomer that can be polymerized with other ethyl 6-aminohexanoate,hydrochloride monomers to form polyelectrolytes. This compound has hydrophobic properties and reacts with functional groups. Ethyl 6-aminohexanoate,hydrochloride is fluorescent and has reactive properties. Polyelectrolytes are polymers that contain multiple charged groups which are able to form ionic bonds with other polymers or ions in solution. Ethyl 6-aminohexanoate,hydrochloride can be used as a crosslinker because it contains two methacrylate groups that react with the amino groups of proteins or polypeptides to form covalent bonds.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(Pyridin-3-yl)butane-1,3-dione is an activating agent that can be used to treat a variety of disorders. It activates the insulin receptor and has been shown to activate the PPAR alpha and gamma heterodimers in vitro. 1-(Pyridin-3-yl)butane-1,3-dione may also have a proliferating effect on cells. This compound is a chelate ring that contains heterocyclic bonds, which are often found in compounds with profiles similar to those of 1-(pyridin-3-yl)butane-1,3-dione. The structural formula for this compound is shown below:

Pyrimidine-2,4,5-triamine is a nucleotide derivative that is used to study the effects of extracellular Ca2+ on cell growth. It has anticancer activity and is used in the treatment of human immunodeficiency virus (HIV) infection and other inflammatory diseases. Pyrimidine-2,4,5-triamine has been shown to inhibit phosphatases, including malonic acid phosphatase and nitro phosphatase. This inhibition leads to an accumulation of malonic acid and nitro compounds which are cytotoxic. The drug also inhibits the production of hydrogen peroxide by inhibiting surface methodology enzymes such as peroxidase or catalase. Pyrimidine-2,4,5-triamine has been shown to be resistant to hydrolysis by hydrophobic effect enzymes such as esterases or glucuronidases. The drug also causes irreversible inhibition of DNA gyrase and topoisomerase

4-Phenoxyphenyl isothiocyanate is a potent anthelmintic drug that has been shown to produce mutations in the DNA of animals. It is a nitro compound that may cause mutagenicity, which is a heritable change in the genetic material. 4-Phenoxyphenyl isothiocyanate has been shown to be mutagenic and has hydroxylamine and thiourea as metabolites. The hydroxylamine metabolite has been shown to be an anthelmintic, whereas the thiourea metabolite was found to be mutagenic. 4-Phenoxyphenyl isothiocyanate is biotransformed into diphenyl ether, which also possesses antimicrobial properties.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold