Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(3R)-5-Oxothiomorpholine-3-carboxylic acid is a lactam antibiotic that inhibits the growth of bacteria by binding to ribosomes. It acts as an analogue of penicillin, but has a higher affinity for the ribosome. The chemical structure of (3R)-5-oxothiomorpholine-3-carboxylic acid consists of a trifluoroacetate ester at the 3 position, which is responsible for its acidic properties. This drug also contains two functional groups at the 5 position, which are responsible for its ability to interact with sulfoxides and eluting chemicals in chromatography. (3R)-5-Oxothiomorpholine-3-carboxylic acid is used in analytical chemistry as a model for other compounds with similar structures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-5-ethylthiophene is a brominated electron donor that has been used as an electron delocalizer in macrocyclic compounds. The electron delocalization is due to the coplanarity of the bithienyl and tetramer rings. 2-Bromo-5-ethylthiophene can be used for the synthesis of polymeric materials, such as polyimides, by lowering the melting point. It is also an excellent reagent for MALDI-TOF analysis in mass spectroscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>4-(2-Dimethylamino-ethoxy)-phenylamine is a synthetic, sustainable, membrane lipid that can form hydrophobic liposomes. These lipids are amphiphilic and form lamellar phases with one or two layers of molecules. The cavity in these phases can be filled with water, which may be useful for optical microscopy. The polymerase chain reaction (PCR) catalyzes the replication of DNA and RNA strands using 4-(2-dimethylamino-ethoxy)-phenylamine to coat the surface of the DNA template strand. This process allows for amplification of small amounts of target DNA sequences for research purposes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2S)-3-Cyclohexyl-2-hydroxypropanoic acid is an organic compound with the chemical formula CHCHOHCOH. It is a white solid that is soluble in water and polar organic solvents. (2S)-3-Cyclohexyl-2-hydroxypropanoic acid has been used for the synthesis of phenylpyruvic acid, which is an intermediate for the production of pharmaceuticals. The molecule has an acidic hydrolysis, which can be carried out through a nucleophilic substitution reaction with cyanide ion. The product of this reaction is phenylacetaldehyde, which can be converted to benzaldehyde. This process is enantioselective because it produces only one chiral form of benzaldehyde from a racemic mixture.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methoxyethyl)(pyridin-2-ylmethyl)amine is a coordination compound that has the ability to bind metal ions. It crystallizes in an orthorhombic system, and its color is light yellow. The oxygen atoms are bound to two halides, which are connected by four tetradentate ligands. 2-Methoxyethyl)(pyridin-2-ylmethyl)amine has a phenolic group with an oxygen atom that forms a molecule with a mononuclear ligand. This substance can be used as a ligand for coordination compounds.</p>

<p>1,2-Bis(4-methoxyphenyl)ethan-1-amine hydrochloride is an optical isomer of the industrial chemical 1,2-diaminobenzene. It has been shown to be a proton source in metal halides, and can be used as a kinetic probe of proton transfer reactions. The functionalities of this compound have been demonstrated by its ability to form carboxylic acids with different functional groups and isomers. The C=N bonds are highly reactive, which leads to the formation of diborane. This molecule has also been shown to be a competitive inhibitor of 6-membered ring enzymes such as reversed-phase HPLC and kinetically competitive inhibition.</p>

<p>1-(2-Bromophenyl)propan-1-one is a chemical compound that is generated from the reaction of bromobenzene and lithium. It is a useful intermediate for the synthesis of various organic compounds, such as cyclopentanones and butyllithium. The reaction proceeds through an intramolecular cyclization in which a ketone reacts with a lithium enolate to form a lactam.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(3-Methoxyphenyl)ethylamine is an enantiomer of the amino acid phenylalanine, and it has been used in the synthesis of racemic drugs. The optical properties of 1-(3-methoxyphenyl)ethylamine are different from those of other amino acids and can be used to create a chiral environment. This molecule can also be used as a calcimimetic that stimulates bone formation by increasing osteoblasts. It also inhibits aminotransferases and increases the production of malic acid, which is important for the synthesis of lactic acid. In addition, this molecule can be used as an efficient method for asymmetric synthesis with organic solvents such as amines or crystallography.</p>

<p>6-Amino-5-oxohexanoic acid hydrochloride is a metabolite of the amino acid 6-aminohexanoic acid. It is excreted in the urine and can be detected by resonance spectroscopy, ion-exchange chromatography, and magnetic resonance spectroscopy. The metabolite has been found to have acidic properties, which can be determined by gas-liquid chromatography. 6-Amino-5-oxohexanoic acid hydrochloride can be used as a biomarker for cerebrospinal fluid and has also been used in biochemical studies to explore the equilibrium between ionized and nonionized forms of acids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-[3-(Dimethylamino)propoxy]aniline is an antimicrobial agent that is a derivative of the amino acid aniline. It has been shown to have antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as fungi. 4-[3-(Dimethylamino)propoxy]aniline has also been found to inhibit the growth of certain antibiotic-resistant bacteria, such as Staphylococcus aureus. This compound is used in pharmaceuticals, including antidepressant agents and antiseptics. 4-[3-(Dimethylamino)propoxy]aniline can be synthesized in two ways: by reacting sodium carbonate with diaminobenzene or by combining toluene with dimethylformamide followed by heating to produce a mixture of isomers.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,2-Oxazole-3-carbohydrazide is an antibacterial agent that belongs to the class of isoxazoles. It has been shown to have antiplatelet properties and is a mesomorphic compound. This drug has also been shown to be active against a variety of bacteria, including Pseudomonas aeruginosa, Staphylococcus pyogenes, and Streptococcus pyogenes. 1,2-Oxazole-3-carbohydrazide has also been found to be effective in treating tuberculosis and may have antitubercular activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Curvularia lunata is a fungus that produces 3-cyclohexyl-3-oxopropanenitrile, an alkylating agent. Curvularia lunata has been shown to be effective in the treatment of inflammatory diseases and allergic diseases. The mechanism of action for its anti-inflammatory effects is not yet known, but it may be due to its ability to reduce the levels of prostaglandins and leukotrienes. Curvularia lunata also contains a chemical called optically active 3-cyclohexyl-3-oxopropanenitrile, which can be used as a starting material for the synthesis of other optically active compounds. Curvularia lunata is used as a natural product to synthesize stereoselective compounds with high optical purity.</p>

<p>Versatile small molecule scaffold</p>

<p>8-Bromonaphthalen-1-amine is an organic compound that belongs to the dipole class of pyrazoles. It has a solute molecule and its orientation can be affected by the inclusion of other solutes. The interaction between 8-bromonaphthalen-1-amine and other molecules can be studied using structural studies and advances in computational chemistry. This compound can also be used to synthesize chiral compounds, as it is a useful synthetic precursor to trifluoride ion.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Pyridin-2-yl)-1,4-diazepane is a ligand that binds to the 5-HT7 receptor, which is expressed primarily in the brain. It has shown low nanomolar affinity for this receptor and has been found to be an antagonist of this receptor. 1-(Pyridin-2-yl)-1,4-diazepane also binds to the dopamine D2 receptor with high affinity and is an antidepressant agent that may be useful for treating depression.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Hydroxy-PEG1-CH2CO2tBu is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, hydroxy-PEG1-CH2CO2tBu is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>Versatile small molecule scaffold</p>

<p>Scriptaid is an inhibitor of DNA methyltransferases that is used to treat infectious diseases. It can inhibit the growth of a wide range of bacteria, including those that are resistant to other antibiotics. Scriptaid has been shown to be effective in vitro against a variety of bacterial strains, including methicillin-resistant Staphylococcus aureus and Mycobacterium tuberculosis. Scriptaid also inhibits the growth of human squamous carcinoma cells and fetal bovine serum cells that have been infected with HIV. In addition, it stimulates the production of neurotrophic factors in human serum, which may be due to its inhibition of histone methylation. The optimum concentration for this drug is not yet known; however, it can inhibit dna methyltransferase at concentrations as low as 1 microgram/ml.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>