Building Blocks

2-(Trimethylsilyl)phenol is an inorganic compound that is used as a reagent to cleave bonds, which can be achieved by the addition of sodium sulfide or ultrasonic extraction. It also reacts with o-glycosylations and fatty acids. 2-(Trimethylsilyl)phenol is used to prepare samples for analysis by gas chromatography, mass spectrometry, or nuclear magnetic resonance spectroscopy.
2- (Trimethylsilyl)phenol is an analytical method that has been developed for the determination of chloride in water samples. This method is based on the protonation of chloride ions followed by bond cleavage reactions with protonated trimethylsilyl phenols and sodium sulfide. The reaction products are then analyzed using gas chromatography or infrared spectroscopy.

4-(Trimethylsilyl)benzoic Acid is a modification of the benzoic acid molecule. It is an organosilicon compound that can be synthesized by reacting trimethylsilyl chloride with 4-aminobenzoic acid in hydrochloric acid at low temperature. This modification has been shown to form nanoribbons when used as a photoelectron emitter, which changes the nature of the molecule. The functional theory and acetylation analysis have been done on this compound, and it has been shown to be centrosymmetric with a diameter of 1 nm. Synthetic yields are not high because temperatures must be maintained below -78°C.

2-(2-Methylbenzenesulfonyl)acetic acid is a heterocycle that belongs to the group of organic compounds. It is a chloride, which is a reactive functional group. The chloride can be found in the subunits of proteins and nucleic acids, which are involved in cell division and metabolism. The chloride ion has been shown to function as an antioxidant by scavenging reactive oxygen species such as hydroxyl radicals and peroxides. 2-(2-Methylbenzenesulfonyl)acetic acid also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This compound has been shown to have neuroprotective effects against Alzheimer's disease and Parkinson's disease, as well as cancerous tumours. 2-(2-Methylbenzenesulfonyl)acetic acid is prepared by reacting hydrochloric acid with an alkylsulfonyl chloride in the presence of an organic

2-Phenylcyclopentan-1-amine is a reconstituted drug that belongs to the group of amines. It is used for the treatment of inflammatory bowel disease, and is also an anti-epileptic drug. 2-Phenylcyclopentan-1-amine has been shown to inhibit mast cell activation and histamine release in rats with experimental colitis. This drug may be effective for the treatment of allergic diseases such as asthma, urticaria, and eczema.

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Cyanobenzotriazole is a labile and reactive compound that has been used as a reagent in organic synthesis, due to its nucleophilic properties. 1-Cyanobenzotriazole can be used in the elimination reactions of amines or as a coupling agent for the formation of nitriles from terminal alkynes. The compound has been used as an analytical method for measuring the concentration of protein, nucleic acid and peptide bonds. 1-Cyanobenzotriazole is also used in the preparation of biomolecules such as proteins, peptides, and oligosaccharides.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Ethylindolin-2-one is a synthetic compound that has been shown to be able to alkylate olefins. It is not yet known what the biological function of 3-ethylindolin-2-one might be. It has been found in leaves, but its presence there is not well understood. The reaction of 3-ethylindolin-2-one with amines gives the corresponding amides, while acylation reactions with alcohols yield esters and other compounds. The addition of 3-ethylindolin-2-one to benzene or butyllithium results in the formation of a new ring system containing three carbons and two nitrogens.

5-Amino-3-phenyl-1,2-oxazole-4-carboxamide (5APOC) is a mitochondria membrane permeable compound that inhibits the growth of cancer cells. 5APOC binds to annexin v, which is a protein found in the outer cell membrane. The binding causes depolarization of the mitochondrial membrane and induces apoptosis. 5APOC also inhibits the growth of colon cancer cells by inhibiting the activity of cytotoxic agents and inducing apoptosis. This drug has been shown to be effective against human colon cancer cells in vitro and in vivo.

2-Cyclopropylglycine is a cyclic amino acid that is synthesized from threonine. It is an important intermediate in the biosynthesis of the aminoacyl-tRNA synthetases. The synthesis of 2-cyclopropylglycine begins with the conversion of threonine to homoserine by a series of reactions called the threonine deaminase pathway. Homoserine is converted to 3-hydroxy-2-methylvaleric acid by hydroxymethylglutaryl-CoA synthase and then to 2-cyclopropylglycine by cyclopropane carboxylic acid reductase, which reduces it to 2-cyclopropylmalonic acid, which is then converted to 2-cyclopropylglycine. This compound binds borohydride and forms an unstable complex with phenolic compounds. The affinity for these substrates depends on the pyrroline ring structure, with

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydrazinoquinoline is a metal chelate that can be used as an analytical method to detect the presence of metals in urine samples. It is also used for the detection of methyl ethyl trifluoroacetic acid and other organic compounds. 2-Hydrazinoquinoline reacts with metal ions to form metal complexes, which are detected by spectroscopy or x-ray diffraction data. The reaction mechanism is not well understood, but it has been shown that reactive intermediates are involved.

Spiro[2.5]octan-6-one is a cyclopropanated biphenylene that reacts with diazomethane to form the chloride, resulting in an electron-rich spiro compound. The chloride is converted to the corresponding electron-deficient biphenylene by treatment with lead tetraacetate and cyclopropanes. The resulting biphenylenes can be reacted with an excess of cyclohexane in the presence of a catalytic amount of oriented Ni(0) to form the vinylcyclopropanes. This reaction can be used for the synthesis of dimers by reacting two vinylcyclopropanes together.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold