Building Blocks

4-Chloro-3-(2,3-dihydro-1H-indole-1-sulfonyl)benzoic acid is a ligand for the receptor for nerve growth factor. It has been shown to be an activator of ion channels and to inhibit protein interactions.

2-[4-(N-Methylthiophene-2-sulfonamido)phenoxy]acetic acid is a peptide that is used as a research tool in the study of protein interactions, antibody, cell biology and pharmacology. It is an inhibitor of ion channels and receptors. 2-[4-(N-Methylthiophene-2-sulfonamido)phenoxy]acetic acid has been shown to activate the nicotinic acetylcholine receptor by binding to it and preventing the displacement of acetylcholine from it.

Versatile small molecule scaffold

Versatile small molecule scaffold

Pyridine-sulfur trioxide complex is a sodium salt of sulfuric acid and pyridine. It is an intramolecular hydrogen acceptor, which means that it can act as a hydrogen donor to other molecules. Pyridine-sulfur trioxide complex has been shown to be effective against HIV infection in vitro. The biological properties of this drug are due to its ability to inhibit the proliferation of cells. Pyridine-sulfur trioxide complex also has antiproliferation activity against a variety of cancers, including prostate, breast, lung, ovarian, and pancreatic cancers. Pyridine-sulfur trioxide complex inhibits fatty acid synthase enzymes and is used as an analytical method for measuring cholesterol levels in the blood.

MLN-4760 is a new chemical entity with potent inhibitory effects against the angiotensin II type 1 receptor. It also has an inhibitory effect on the renin-angiotensin system, which is involved in regulating blood pressure and heart function. MLN-4760 binds to the angiotensin II type 1 receptor and blocks its interaction with angiotensin II, leading to reduced cardiac hypertrophy, heart failure, and death in animal models of cardiac hypertrophy. In addition, MLN-4760 has been shown to have antitumor properties in vitro and in vivo. This compound is a natural product that was isolated from Chinese herbs used for centuries for their therapeutic benefits.

Please enquire for more information about 2,6-Lutidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Methoxy-4-nitrobenzaldehyde (3MNB) is a biomolecular that is used to study nucleophilic substitutions. It has been shown to inhibit the growth of cells in culture, specifically those with fatty acid amides. 3MNB inhibits the synthesis of β-amyloid, a protein associated with Alzheimer's disease. 3MNB also has potent inhibitory activity on chloride channels and phenylhydrazone binding sites, which are targets for antipsychotic drugs. 3MNB inhibits the production of sh-sy5y cells and piperazine binding sites in the brain. The inhibition of these sites leads to an improvement in memory and learning ability.

3-Iodo-1-(phenylsulfonyl)indole (3-ISI) is a ligand that is used to crystallize metal ions. 3-ISI binds to metal ions through interactions with the halide ion. The 3-ISI molecule has two phenylsulfonyl groups and one iodine atom, which are the sites of coordination to metal ions. Friedel-Crafts acylation reactions use 3-ISI as a ligand because it does not react with the catalyst or acid, but can be easily replaced by other ligands during the reaction. Parameters for determining its structure include X-ray crystallography, NMR spectroscopy, IR spectroscopy, and elemental analysis. The chloride anion in 3-ISI is able to form hydrogen bonds with other chloride anions in order to stabilize its structure.
3-ISI can be synthesized by reacting iodides with benzyl bromide and phosphorous pent

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Pyridylmethylphosphonic acid is an inorganic compound that is a ligand for the metal Ruthenium. It is used in organic synthesis as a photosensitizer and a potentiometric titrant. The ligand binds to the metal through one or more of its oxygen atoms, forming a coordination complex. The bond cleavage reaction occurs when the molecule absorbs light of sufficient energy, causing it to break into two parts. 4-Pyridylmethylphosphonic acid is not very soluble in water and is therefore used as an electrolyte in potentiometric titrations. The pH of the solution will change depending on the concentration of the acid. 4-Pyridylmethylphosphonic acid can also be used as a catalyst for certain organic reactions such as esterification and transesterification reactions.

4-[(1H-Pyrazol-1-yl)methyl]phenol (4PMP) is an inhibitor of dopamine beta-hydroxylase that has been studied in assays with dopamine and noradrenaline. It has been shown to activate both noradrenaline and dopamine receptors, and can be used as a tool for the study of blood pressure regulation. 4PMP also increases reactive oxygen species production, which may be due to its ability to react with cyanide ions. The binding of 4PMP to the enzyme is reversible and competitive. The pH profile of 4PMP has also been studied, with a range from 2 to 5.4. Kinetic studies have shown that the reaction rate for 4PMP is best described by a Michaelis-Menten kinetic model, with a Km value of 0.03 mM and Vmax value of 9.3 μM/min for dopamine β-hydroxylase inhibition. There are

Versatile small molecule scaffold

Thiomorpholine-3,5-dione is a chemical compound that has an x-ray crystal structure. It was first synthesized in 1892 and was the first organic molecule with a herringbone molecular geometry to be discovered. Thiomorpholine-3,5-dione is used as a precursor for dyes, pharmaceuticals, and other organic compounds.

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Bromo-4-phenylbutan-2-one is an efficient method for the synthesis of secretory phospholipase A2 (sPLA2) inhibitors. This compound has been shown to inhibit a number of sPLA2 enzymes in vitro and in vivo, including those from human neutrophils, rat peritoneal macrophages, and rat pancreatic acinar cells. 3-Bromo-4-phenylbutan-2-one is hydrolyzed by a number of reagents, including acids and bases. It can also be used as a starting material for the synthesis of potent sPLA2 inhibitors with nonpancreatic activity.

2-Chloro-1-(furan-2-yl)ethan-1-one is a selenium compound that has been shown to have anti-inflammatory properties. This drug binds to the reactive oxygen species produced by the inflammation and prevents them from damaging cells. 2-Chloro-1-(furan-2-yl)ethan-1-one also has an effect on metabolic disorders, such as diabetes mellitus, where it inhibits the synthesis of amines that can lead to ketosis. It is also used to treat hepatitis, which may be due to its ability to inhibit the growth of bacteria. This drug has been shown to have antimicrobial activity against Mycobacterium avium and other infectious diseases.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about Boc-4-(4-fluorophenyl)-piperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Bromo-1,3,5-triisopropylbenzene is an ethylene acetal that is prepared by the catalyzed reaction of aryl chlorides and anhydrous zinc bromide in the presence of triethylamine. The selectivities of this method are high because it can produce mainly a single isomer. The stereoselectivity is also high because the reaction proceeds with the formation of only one stereoisomer. The mechanism for this reaction involves a nucleophilic substitution of the halogenated aryl chloride with the trialkylborane, which generates two different products. This product has been used in the synthesis of biphenyls and nitro compounds.

Please enquire for more information about 5-Bromo-1-methyl-1H-1,2,3-triazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Bromo-1-methyl-1H-imidazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Succinylcholine is a depolarizing neuromuscular blocking agent that is used in surgical procedures. Succinylcholine hydrolyzes to succinic acid and choline in vivo and is metabolized by the liver. The half-life of succinylcholine is about 2 minutes in humans. It has been shown that this drug causes respiratory paralysis, but only at high doses. Succinylcholine also has potent cardiac effects, which are due to its ability to block nicotinic acetylcholine receptors on the heart muscle. It was found that succinylmonocholine (a metabolite of succinylcholine) can be detected in urine samples after administration of this drug with a kinetic data analysis method. This method uses LC-MS/MS to measure the concentration of succinylmonocholine in human serum and isolated heart tissue samples. A pharmacokinetic study showed that succinycholines accumulation rate constant was 0.051 ± 0.

Versatile small molecule scaffold