Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(3-Chlorophenyl)-1H-pyrazole-4-carbaldehyde is a pesticide that acts as a selective insecticide. It is effective against the larval stage of insects, such as the cabbage moth, Plutella xylostella. This compound has been shown to have biological activity against mites and insects with hydrazine hydrochloride and cinnabarinus. 1-(3-Chlorophenyl)-1H-pyrazole-4-carbaldehyde has also been shown to be able to cyclize with hydrazine to form an insecticidal compound.

Versatile small molecule scaffold

Versatile small molecule scaffold

tert-Butyl 5-nitroisoindoline-2-carboxylate is a platelet inhibitor that belongs to the group of antagonists. It has been shown to inhibit human platelets and inhibit the aggregation of fibrinogen. Tert-butyl 5-nitroisoindoline-2-carboxylate has also been shown to have high potency in animal models, but it is not yet known whether it will be effective in humans. The drug has been shown to be a potent antagonist at the platelet P2Y12 receptor, which mediates platelet aggregation and activation, as well as inhibiting ADP-, collagen-, thrombin-, and epinephrine-induced aggregation. Tert-butyl 5-nitroisoindoline-2-carboxylate may also act as a surrogate for agonists or mimetics of the P2Y12 receptor.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,6-Diaminopyridine-3-carbonitrile (CAS No. 20520-22-4) is a synthetic dyestuff with red color and low solubility in water. It has been used as a dye for polyester and other synthetic fibers. The dye is soluble in organic solvents such as ethoxycarbonylethyl acetate and benzene, but insoluble in water. In addition to the red color, 4,6-diaminopyridine-3-carbonitrile has good lightfastness properties. This chemical is also a precursor to diazotized compounds that can be used to produce hydrogenated hydrocarbons.

Versatile small molecule scaffold

3-Methyl-8-hydroxyquinoline (3MQ) is a chemical compound that has been shown to be an inhibitor of the enzyme cyclen. 3MQ binds to the active site of cyclen and blocks the binding of calcium ions, preventing the formation of calcium complexes with cyclen. This inhibition leads to a decrease in cyclen activity and an increase in the synthesis of protein. 3MQ has also been shown to be potent inhibitor against chloride ion currents through voltammetry experiments. It was found that its redox potential is very low, which suggests that it can be used as a probe for electron transfer reactions in cells. The photophysical properties of 3MQ have also been studied and it was found that this molecule absorbs light at wavelengths between 400–600 nm, which may lead to its use as a photosensitizer or photoantagonist for photodynamic therapy.

4-Hydroxy-N-(2-hydroxyethyl)benzamide (4OHEBA) is a natural product that belongs to the class of phenolic compounds. It is found in macroalgae and has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. 4OHEBA has also been shown to have chemical diversity and studies show that it can be used in preservative systems.

Versatile small molecule scaffold

3,4-dihydro-2H-1-benzopyran-6-amine is an olefinic, reactive chemical that is used as an excipient in the preparation of polyenes. It can be used as a reactant to form heterocycles and unsaturated fatty acids. 3,4-dihydro-2H-1-benzopyran-6-amine has been shown to inhibit platelet aggregation and has been used as a ligand for the study of chemical reactions. This drug also has a wittig reaction with amido compounds to form hydrocarbon groups.

Versatile small molecule scaffold

Versatile small molecule scaffold

Dimethyl 2,4-dibromoglutarate is a stereospecific, unselective opioid receptor ligand. It interacts with the opioid receptors and has been shown to have affinity for both mu and kappa receptors. Dimethyl 2,4-dibromoglutarate has been studied as a potential model for morphine and other selective ligands. The two enantiomers of dimethyl 2,4-dibromoglutarate were synthesized in order to study their selectivity for the opioid receptor. The racemic mixture of dimethyl 2,4-dibromoglutarate was found to be more potent than either of the individual enantiomers. The cyclopropane ring on the left side of the molecule is responsible for this effect. This ring confers higher affinity and selectivity than that on the right side of the molecule.

2,2',4,4'-tetrahydroxybenzophenone is a hydroxylated benzophenone that has immunomodulatory effects. It binds to the receptor in the immune system and can cause an increase in cytokine production. 2,2',4,4'-tetrahydroxybenzophenone is cytotoxic and has significant toxicity in vitro. The molecule has been shown to disrupt mitochondrial membrane potential. This may be due to its ability to form hydrogen bonds with molecules on the mitochondrial membrane. 2,2',4,4'-tetrahydroxybenzophenone also modulates transcriptional regulation of genes involved in cell proliferation and apoptosis. The drug is detectable at low levels by mass spectrometry and is not known to have any toxicological effects.END>>

Versatile small molecule scaffold

Isononyl alcohol is a polycarboxylic acid that has been used in the treatment of skin conditions, such as atopic dermatitis and psoriasis. It has been shown to penetrate the skin and stimulate the production of sebum. Isononyl alcohol is also used as a plasticizer for polyvinyl chloride (PVC) and other plastics, which increases their flexibility. This chemical also has a hydrophobic effect, which may be due to its hydroxyl group. The unsaturated alkyl chain on this chemical also makes it susceptible to oxidation by ozone in air and water vapor in air. Isononyl alcohol is metabolized by humans through conjugation with glucuronic acid or sulfate esters.

Versatile small molecule scaffold

2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.
2-Acetylbenzoic Acid

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

2-Phenoxyaniline is a nitro compound that can be converted to the corresponding palladium complexes. It is an inhibitor of the acylation reaction, which is a type of chemical reaction in which an organic molecule reacts with an acid. The inhibition of this reaction has been shown to have an effect on heart disease, specifically by lowering cholesterol levels and reducing atherosclerosis. 2-Phenoxyaniline has also been shown to inhibit the activation energy for electron transfer reactions, making it useful as a catalyst in analytical methods. 2-Phenoxyaniline also undergoes vibrational spectroscopy when exposed to liquid chromatography and other analytical methods.

Ethyl 3-formyl-1H-pyrrole-2-carboxylate is a formyl compound with the molecular formula C8H8O3. It is a colorless liquid that has a strong odor. The compound can be obtained by the reaction of ethyl acetoacetate and pyrrole in the presence of aluminum chloride. The compound has been studied for its nuclear magnetic resonance (NMR) properties. It has two conformers, which are distinguished by their different chemical shifts, and this difference can be used to study coupling between the carbonyl group and other groups in the molecule.

Versatile small molecule scaffold

Versatile small molecule scaffold

Trans-1,2-Dichloroethylene is a chlorinated hydrocarbon that is used in the production of polyvinyl chloride plastics. When ingested at dietary concentrations, trans-1,2-Dichloroethylene may cause liver damage and death in CD-1 mice. Trans-1,2-Dichloroethylene has been shown to react with nucleophilic substitutions and produce toxic reaction products. This chemical also causes polymerase chain reactions that can lead to cell death. The effective dose for this chemical is unknown because it has not been tested in clinical trials.

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about H-Ser-Ala-Glu-Glu-Tyr-Glu-Tyr-Pro-Ser OH trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page