Reagentes Sintéticos

<p>Applications Orally active inhibitor of central and peripheral catechol-O-methyltransferase (COMT). Antiparkinsonian.<br>References Dingemanse, J., et al.: Clin. Pharmacol. Ther., 57, 508 (1995), Keating, K.A., Drugs, 19, 165 (2005),<br></p>

<p>Applications Sofalcone is a substituted chalcone with anti-ulcer activity.<br>References Matsuo, Y., et al.: Arzneim. Forsch., 33, 242 (1983), Suwa, T., et al.: Jpn. J. Pharmacol., 35, 47 (1984),<br></p>

<p>Applications Sodium Pyrophosphate Decahydrate is a tetrabasic pyrophosphate salt used in buffers.<br></p>

<p>Applications A novel nonsteroidal FXR nuclear receptor agonist.<br>References Makishima, M., et al.: Science, 284, 1362 (1999), Wang, H., et al.: Mol. Cell, 3, 543 (1999), Zhang, Y., et al.: J. Biol. Chem., 276, 43018 (2001), Carlton, V.E., et al.: Nat. Genet., 34, 91 (2003),<br></p>

<p>Applications Sodium selenite is used in reducing carcinogenesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Sodium Phosphate Buffer Solution is used in the development of liquid chromatographic assay for determination of opicapone and BIA 9-1079 in rat matrixes. in the design of novel pyrimidin-4(3H)-one hydroxamate derivatives that showes inhibitory activity against histone deacetylase and exhibited antiproliferative activities against human cervical cancer HeLa and lung carcinoma A549 cells.<br>References Lu, H., et al.: Chem. Res. Chin. Univ., 32, 576 (2016); Goncalves, D., et al.: Biomed. Chromatogr., 30, 312 (2016)<br></p>

<p>Applications Trimethylamine is used as a reagent in the synthesis of L-Carnitine (C184110); an essential cofactor of fatty acid metabolism. L-Carnitine is required for the transport of fatty acids through the inner mitochondrial membrane and is synthetized primarily in the liver and kidney.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004); Wu, J., et al.: Faming Zhuanli Shenqing. CN 104030934 A 20140910. Sep 10, 2014<br></p>

<p>Applications Tetramethylammonium Hydroxide Pentahydrate is a useful compound for preparing gamma-cesium lead iodide films for high-efficiency deep-red light-emitting devices.<br>References Yi, C., et al.: Nat. Commun., 11, 4736 (2020)<br></p>

<p>Applications A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).<br>References David, E., et al.: Blood, 116, 5285 (2010); Nagai, T., et al.: Leukemia Res., 34, 1057 (2010); Hong, D., et al.: Clin. Cancer Res., 15, 7061 (2009)<br></p>

<p>Applications 3,3-Diphenylpropylamine is a metabolite of Prenylamine (P712800). 3,3-Diphenylpropylamine showed antiextensor effects as well as neuroexcitatory effects and antagonized barbital-induced loss of the righting reflex.<br>References Hornke, I. et al.: Arzneim.-Forsch., 20, 791 (1970); Remberg, G. et al.: Biomed. Mass Spec., 4, 197 (1977); Helke, C. et al.: Eur. J. Pharmacol., 48, 231 (1978);<br></p>

<p>Applications Bepotastine is a histamine H1 receptor antagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).<br>References Kaminuma, O. et al.: Biol. Pharm. Bull., 21, 411 (1998); Kitaba, S. et al.: J. Allergy, No pp. given (2008); Lyseng-Williamson, K.A., Drugs, 70, 1579 (2010);<br></p>

<p>Applications Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase.<br></p>

<p>Applications 6-O-α-D-Maltosyl-β-cyclodextrin is an additive to improve the solubility of quetiapine.<br>References Ogawa, N., et. al.: Chem. Pharm. Bull., 31, 809 (2013)<br></p>

<p>Applications 2-Amino-6-fluorobenzothiazole is a useful research chemical. An intermediate for the synthesis of benzothiazoles and aminobenzothiazoles with antimicrobial activity.<br>References Defrenza, I., et al.: J. Heterocycl. Chem., 52, 1705 (2015); Catalano, A., et al.: Eur. J. Med. Chem., 64, 357 (2013)<br></p>

<p>Applications Phosphoric Acid Monosodium Salt Dihydrate, is a reagent widely used in the preparation of biological buffers. It is highly hygroscopic and can be used in many applications including in gel electrophoresis.<br>References Salaun, F.: "Influence of mineral environment on the buffering capacity of casein micelles", "Milchwissenschaft", 62(1):3<br></p>

<p>Applications Thioisonicotinamide is an impurity of Ethionamide (E890420) with tuberculostatic activity.<br>References Pappalardo, G. et al.: Farm. Ediz. Sco., 22, 808 (1967); Waisser, K. et al.: Cesk.-Slov. Farm., 33, 99 (1984); Devani, M. B. et al.: J. Pharmac. Sci., 43, 1471 (1974);<br></p>

<p>Applications 3-acetylindole (cas# 703-80-0) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications Choline Hydroxide acts as an efficient catalyst for the synthesis of trans-2,3-dihydrofuro[3,2-c]coumarins. Also, it is used to prepare aqueous two-phase systems (ATPS) with polypropylene glycol. Efficient basic ionic liquid catalyst for the synthesis of α-hydroxyphosphonates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, M., et al.: J. Chem. Res., 40, 655-658 (2016); Lee, S. Y., et al.: Sep. Purif. Technol., 179, 152-160 (2017); Kalla, R. M., et al.: New J. Chem., 41, 5373-5379 (2017)<br></p>

<p>Applications (R)-RuCl[(p-cymene)(BINAP)]Cl is a ruthenium BINAP catalysts.<br>References Yue, C., et al.: Yingyong Huagong, 43, 1042 (2014); Bernas, H., et al.: Catal. Sci. Technol., 2, 1901 (2012)<br></p>

<p>Applications Samarium, can be used in the reduction of arylsulfonyl chlorides and arylsulfinates in combination of titanium(IV) chloride to make diaryl disulfides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janjetovic M. et. al.: Journal of physics. Condensed matter : an Institute of Physics journal, 25(2), undefined (2012-12-5)<br></p>

<p>Applications Potassium hydrogen fluoride (cas# 7789-29-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Chloropropanoic acid is a component of the oil-based lubricoolant SP-4. It is also a neurotoxicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ermolaeva, N. V., et al.: Ekologiya Urbanizirovannykh Territorii, 2, 39-43 (2015); Pritt, Michael L., et al.: Toxicological Sci., 141(2), 398-408 (2014)<br></p>

<p>Applications Trichloroacetic Anhydride is used in organometallic reactions as well as oxadiazole containing 5-lipoxygenase activating protein inhibitors.<br>References Takahashi, H. et al.: J. Med. Chem., 58, 1669 (2015);<br></p>

<p>Applications Bariumhydroxidemonohydrate (cas# 22326-55-2) is a useful research chemical.<br></p>

<p>Applications 2,4-Dichlorobenzoyl Chloride is a reactant used in the synthesis of aroyl(sulfamoylphenyl)thiourea derivatives as 15-lipoxygenase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mahdavi, M., et. al.: Eur. J. Med. Chem., 82, 308 (2014)<br></p>

<p>Applications Zinc Bromide is used as a catalyst in the synthesis of tetrazoles which exhibit antibacterial activity in vitro. Zinc Bromide is also a zinc salt that is added as a nutritional or functional ingredient in food and oral care products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cui, J., et al.: Xiandai Shengwuyixue Jinzhan, 12, 3478 (2012); Keast, R.S.J.: J. Food Sci., 68, 1871 (2003)<br></p>

<p>Applications 1,​2-​Bis(trimethylsiloxy)​ethane is an organic reagent, used in the preparation of nonracemic hexahydrofurapyranol which acts as a high-affinity ligand for HIV-1 protease inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ghosh, A. et al.: Tetra. Lett., 58, 3230 (2017)<br></p>

<p>Applications (R)​-​[2,​2'-​Bis(diphenylphosphin​o)​-​1,​1'-​binaphthyl]​dichlororuthenium is a catalyst used in the synthesis of helicobacter pylori lipopolysaccharide structures displaying anti-inflammatory activiy.<br>References Shimoyama, A. et al.: Chem. A Eur. J., 17, 14464 (2011);<br></p>

<p>Applications Copper(I) cyanide is useful as a catalyst and as a reagent in the preparation of nitriles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dieter, R.K., et al.: J. Org. Chem., 79, 1125 (2014);<br></p>

<p>Applications Aluminum Sulfate Hydrate is used in the synthesis of aluminum diethylphosphinate. Also used in the preparation of nanowires through a molten salt method.<br>References Yang, L. et al.: Chin. Chem. Lett., 22, 385 (2011); Huo, K. et al.: J. Nanosci. Nanotechol., 10, 4792 (2010);<br></p>

<p>Applications Protected D-Glucitol.<br></p>

<p>Applications Cerium Chloride, can be used as a starting point for the preparation of other cerium salts. It also plays an important role in organic synthesis for alkylation of ketones.<br>References Norioki, M., et al.: Chem. Lett., 15(3), 357 (1986); Luche, J. L., et al.: J. Chem. Soci., 14, 601 (1978);<br></p>

<p>Applications 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters.<br>References Picard, F. et al.: J. Med. Chem., 45, 3406 (2002); Donkor, I. et al.: J. Med. Chem., 51, 4346 (2008);<br></p>

<p>Applications DI-TERT-BUTYLSILANE (cas# 30736-07-3) is a useful research chemical.<br></p>

<p>Applications N-Aminohexamethylenimine is a sesquiterpene lactones with anti-hepatitis C virus activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rossini, M., et al.: Lett. Drug. Des. Discov., 9, 881 (2012); Hines, R.N., et al.: J. Pharmacol. Exp. Therap., 214, 88 (1980);<br></p>

<p>Applications POTASSIUM HEXAFLUOROPHOSPHATE (cas# 17084-13-8) is a useful research chemical.<br></p>

<p>Applications (+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane is a chiral reagent that is used as a catalyst and also as an enantioselective reagent in synthetic chemistry.<br>References Martin, N.: Electrochem. Soc. Interface, Yang, L., et al.: Eur. J. Org. Chem., 2013, 4434 (2013)<br></p>

<p>Applications Sodium Hydrogen Sulfate is used in production of Nickel Hydroxide Electrode material for Alkaline battery.<br>References Naboka, O., et al.: Eur. Pat. Appl., (2020);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrobenzyl Chloroformate is used in the preparation of prodrugs of cytotoxic acridines used in conjunction with enzyme prodrugs which counter carcinoma cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asche, C. et al.: Bioorg. Med. Chem. Lett., 16, 1990 (2006); Hay, M. et al.: J. Med. Chem., 46, 2546 (2003);<br></p>

<p>Applications Manganese Chloride Tetrahydrate is an inorganic chemical reagent used in oxidation studies and reactions.<br>References Huynh, M. et al.: J. Am. Chem. Soc., 136, 6002 (2014); Gupta, Y. et al.: Res. J. Chem. Env., 16, 48 (2012);<br></p>

<p>Applications 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.<br>References Chu, X., et al.: J. Med. Chem., 49, 6549 (2006); Thevenin, M., et al.: Bioorg. Med. Chem., 21, 4885 (2013)<br></p>

<p>Applications 2-(2-Bromoethoxy)tetrahydro-2H-pyran, is an heterocyclic building block used in the synthesis of various chemical compounds.<br></p>

<p>Applications [((R,R)-2-Amino-1,2-diphenylethyl)[(4-tolyl)sulfonyl]amido](chloro)(η6-p-cymene)ruthenium is an catalyst used for enantioselective hydrogenation of quinolines, N-Alky Ketimines and antitumor, antiproliferative derivatives of natural products isolated from bacteria.<br>References Son, S.M., et al.: J. Org. Chem., 79, 2666 (2014); Liu, Y., et al.: J. Org. Chem., 78, 12009 (2013); Fang, Z.J., et al.: J. Org. Chem., 78, 8594 (2013);<br></p>

<p>Applications Dichloroacetyl Chloride is a reagent used in the synthesis of substituted benzothiazoles exhibiting antitumor and anticancer activity.<br>References Chua, M. et al.: J. Med. Chem., 42, 381 (1999);<br></p>

<p>Applications Sodium Hydrosulfide Hydrate is a stable hydrogen sulfide (H2S) donor and oxidant in the formation of benzothiazoles. It is also used as a reagent in the synthesis of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, J., et al.: Int. J. Impot. Res., 25, 86 (2013); Park, N., et al.: Eur. J. Org. Chem., 2012, 1984 (2012); Vu, C.B., et al.: J. Med. Chem., 52, 1275 (2009)<br></p>

<p>Applications Selenium(IV) Oxide, is an important reagent in organic synthesis. Oxidation of paraldehyde (acetaldehyde trimer) with SeO2 gives glyoxal and the oxidation of cyclohexanone gives cyclohexane-1,2-dione.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hatch, C. C., et al.; Org. Synth., 4, 229 (1963); Ronzio, A. r., et al.: Org. Synth., 3, 438 (1955);<br></p>

<p>Applications Sodium Peroxide is a strong oxidizing agent.<br> E0<br></p>

<p>Applications Cumylamine is a reactant in the preparation of anti-malarial drugs. Also used in the preparation of HCV inhibitors.<br>References Ciana, C. et al.: Bioorg. Med. Chem. Lett., 23, 658 (2013); Girijavallabhan, V. et al.: Bioorg. Med. Chem. Lett., 22, 5652 (2012);<br></p>

<p>Applications Trimethyl Orthoformate is a reagent in the synthesis of CDK2/Cyclin A as antitumor agents derived from 3-aminopyrazole molecules. Also used in the preparation of PLD1/PLD2 selective inhibitors that decrease invasive migration of glioblastoma cells often associated with tumor progression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pevarello, P. et al.: J. Med. Chem., 48, 2944 (2005); O'Reilly, M. et al.: J. Med. Chem., 56, 2695 (2013);<br></p>

<p>Applications Chloro(triphenylphosphine)gold(I) is a coordination compound.<br></p>

<p>Applications Diphenylphosphine oxide (cas# 4559-70-0) is a useful research chemical.<br></p>

<p>Applications A derivative of Loratadine as dual antagonist of platelet activating factor (PAF) and histamine.<br>References Piwinski, J.J., et al.: J. Med. Chem., 34, 457 (1991),<br></p>

<p>Applications Copper(I) Chloride, has many applications. The main use of copper(I) Chloride is as a precursor to the fungicide copper oxychloride. In organic synthesis, CuCl is used as an initiator of radical reactions such as the hydrostannation of α,β-unsaturated ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wade, L. G., et al.: Org. Chem., 5th Ed., 871 (2003); Ooi, T., et al.: Tetrahedron Lett., 40, 2133 (1999);<br></p>

<p>Stability Hygroscopic<br>Applications Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.<br>References Freeman, J., et al.: Pediatrics, 102, 1358 (1998), Thio, L., et al.: Neurology, 54, 325 (2000), Rho, J., et al.: Epilepsia, 43, 358 (2002),<br></p>

<p>Applications (S)-(-)-Glycidol is a cyclic AB 2-type monomer that can be polymerized in a ring-opening multibranching polymerization. S)-(-)-Glycidol is also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chiummiento, L., et al.: Tetrahedron, 65, 5984 (2009); Tokar, R., et al.: Macromolecules, 27, 320 (1994)<br></p>

<p>Applications cis-1-Ethoxy-2-(tributylstannyl)ethene is used in the synthesis of (+)-pleuromutilin (P610500), an antibiotic substance produced by the basidiomycetes Pleurotus mutilus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fazakerley, N.J., et. al.: Chem. Eur. J., 19, 6718 (2013)<br></p>

<p>Applications 2-Ethyl-2-methyl-1,3-dioxolane is used as a reagent in the synthesis of Strychnine Hydrochloride (S687710); a compound that acts as an antagonist for cholinesterases and beta amyloid aggregation. Also used as a reagent in the study of the prodrugs of peptide aldehyde as proteasome inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ohshima, T., et al.: Tetrahedron, 60, 9569 (2004); Han, L., et al.: J. Chin. Pharm. Sci., 21, 21 (2012)<br></p>

<p>Applications Potassium Hexamethyldisilazane is used in the preparation of 5-azacytidine, an antineoplastic drug. Also used in the preparation of β3-AR agonists used in anti-stress formulations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vujjini, S. et al.: Org. Proc. Res. Dev., 17, 303 (2013); Xu, F. et al.: Org. Lett., 15, 1342 (2013);<br></p>

<p>Stability Light Sensitive<br>Applications Butyl Nitrite is reagent used in the preparation of p-hydroxyphenylpyruvate dioxygenase inhibitors which has herbicidal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Witschel, M., Bioorg. Med. Chem., 17, 4221 (2009)<br></p>

<p>Applications Sodium Bismuthate, is an inorganic compound, which is a strong oxidiser. Sodium Bismuthate converts almost any manganese compound to permanganate, which is easily assayed spectrophotometrically.<br>References Kitchin, J., et al.: Encyclopedia of Reagents for Organic (2001); Seiburger, Ch., et al.: Revista de la Asociacion Argentina de los Quimicos y Tecnicos de la Industria del, 8, 73 (1967);<br></p>

<p>Applications 5-Bromoindoline is a brominated indoline derivative and a product of biocatalyzed halogenation of nucleobase analogs. 5-Bromoindoline is used in the synthetic preparation of biologically active compounds such as selective human β3 adrenergic receptor agonists.<br>References Mathvink, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 1869 (1999); Medici, R. et al.: Biotechnol. Lett., 33, 1999 (2011);<br></p>

<p>Applications Phenylselenyl Bromide is used as a reagent in the synthesis of the antihyperglycemic agent, (+)-Antroquinonol. Phenylselenyl Bromide is also used in the preparation of 9-epi-Artemisinin (A777505); the chiral isomer of Artemisinin (A777500) which is an antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sulake, R.S., et al.: J. Org. Chem., 80, 6044 (2015); Orabi, K.Y. et al.: Phytochem., 51, 257 (1999); Jefford, C.W. et al.: Helv. Chim. Acta, 83, 1239 (2000); Klayman, D.L., et al.: Science, 228, 1049 (1985)<br></p>

<p>Stability Moisture Sensitive<br>Applications Used in tests for skin corrosivity.<br> E0<br>References Fentem, J.H., et al.: Toxicology in Vitro, 12, 483 (1998),<br></p>

<p>Applications Methyl cyanoformate is a reagent that is used in the preparation of XEN907, which is a spiro-oxindole blocker of Nav1.7 for the treatment of pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chowdhury, S., et al.: Bioorg. Med. Chem. Lett., 21, 3676 (2011);<br></p>

<p>Applications 4-Aminomorpholine (cas# 4319-49-7) is a useful research chemical.<br></p>

<p>Applications 3-Chloro-2,4-pentanedione is an useful building block reagent in the preparation of organic compounds of research interest that has been studied as a possible β-​diketone for antitumor treatment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nakano, K., et. al.: Anticancer Res., 24, 711 (2004);Lever, A. B. P.: Inorg. Chem., 29, 1271 (1990);Dawood, K., et. al.: Bioorg. Med. Chem., 14, 3672 (2006)<br></p>

<p>Applications Di-O-acetyl-L-tartaric Anhydride (cas# 6283-74-5) is a compound useful in organic synthesis.<br></p>

<p>Applications n-Butyltriphenylphosphonium Bromide is used in the synthesis of inhibitors of tubulin polymerization thus expressing antimitotic and antitubulin properties. Also used in the synthesis of 3-phenylpropanoic acids as peroxisome proliferator-activated receptor dual agonists affecting the mitochondrial carnitine system.<br>References Cushman, M. et al.: J. Med. Chem., 38, 2041 (1995); Laghezza, A. et al.: J. Med. Chem., 56, 60 (2013);<br></p>

<p>Applications Boron trifluoride acetic acid complex is used as a catalyst for the synthesis of fluoro ethers and thioamides.<br>References Gros, L., et al.: Chem. Heterocycl. Compd., 42, 176-79 (2006); Tamura, E, et al.: Jpn. Kokai Tokkyo Koho 22 pp. Patent 1999 CODEN:JKXXAF;<br></p>

<p>Applications Chloro(triethylphosphine)gold is an analogue of auranofin. Auranofin and its analogs show antimicrobial activity against multidrug-resistant pathogens<br>References Tizian M. et al.: Chem. Med. Chem. 13(22), 2448-2454 (2018)<br></p>

<p>Applications (4-Nitrophenyl)acetic Acid used in the synthesis of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones which may act as angiogenesis inhibitors. Also used in the one step construction of amino-substituted squaraine dye.<br>References Kirk, N., et al.: Bioorg. Med. Chem. Lett., 26, 1813 (2016); Ying, H., et al.: Dyes Pigments, 131, 264 (2016);<br></p>

<p>Applications Lithium bromide is used as an inexpensive catalyst for the opening of epoxide rings by amines at room temperature. Lithium bromide is also used in conjunction with water to create a refrigerant-absorbent solution for use in refrigeration systems.<br>References Arun, M., et al.: Appl. Therm. Eng., 21, 1273 (2001); Chakraborti, A., et al.: Eur. J. Org. Chem., 17, 3597 (2004)<br></p>

<p>Applications Benzeneruthenium(II) Chloride Dimer is a catalyst for SNAr reactions of fluoroarenes and cyclic amines, a precatalyst for the hydrogenation of β-keto esters and a precursor for the preparation of other ruthenium catalysts.<br></p>

<p>Applications A chiral derivative of Camphor.<br>References Peng, R., et al.: Biochem. Pharmacol., 35, 1391 (1986), Tanaka, E., et al.: Biochem. Pharmacol., 41, 472 (1991),<br></p>