Álcoois

Applications 1-Mesyl-2-azidoethanol is an intermediate in the synthesis of dopamine D1/D3 heterodimer to Investigate Hetero-Oligomer binding properties.
References Hounsou, C., et al.: ACS. Chem. Biol., 10, 466 (2015);

Applications 3,7-Dimethyl-6-octen-1-yn-3-ol is a useful synthetic intermediate in the synthesis of Methylisopseudoionone (M314920); a derivative of Ionone (I731275) which is an aroma compound found in essential oils such as rose oil, and thus can be used in the perfumery industry.
References Susanne, B. et al.: J. Exp. Botany, 61, 2967 (2010); Hu, H. et al.: Arch. Pham. res., 32, 699 (2009)

Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.
References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides & Nucleotides, 2, 21 (1983)

Stability Epimerize in solution
Applications 5-Hydroxy-1,3-oxathiolane-2-carboxylic Acid is used in the synthesis of potent antiviral agent (-)-2’-Deoxy-3’-thiacytidine and its enantiomer.
References Jin, H.L., et al.: J. Org. Chem., 60, 2621 (1995);

Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.

Applications Thietan-3-ol (cas# 10304-16-2) is a useful research chemical.

Applications 2-[(Tributylstannyl)methyl]-2-propen-1-ol is a useful reagent for organic synthesis.

Applications 2-(Octadecyloxy)Ethanol (cas# 2136-72-3) is a useful research chemical.

Applications 1,3-Bis(2-acetylphenoxy)-2-propanol is a useful research intermediate.
References Sangwan, N. K., et al.: Indian J. Chem. B. Org. Chem. Incl. Med. Chem. ,31B, 590 (1992)

Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. & Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)

Applications 4-Hydroxy Bisphenol A (2,3-Dihydroxypropyl) Ether is an intermediate in the synthesis of Bisphenol A (2,3-dihydroxypropyl) Glycidyl Ether (B519590), an epoxide that is used as a starting substance in the manufacturing of can coatings for food-contact applications, pharmaceutial creams and may produce reaction products migration from the coating.
References Coulier, L.: J. Agric. Food. Chem., 58, 4873-4882 (2010):0; Soeborg, T.: Dansk Kemi, 87, 24-27 (2006).

Applications 1,10-Decanediol is a substance used in the pharmaceutical study on the composition of essential oils obtained from myrrh and frankincense and their potential anticancer activities. Also used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity.
References Chen, Y., et al.: Oncol. Lett., 6, 1140 (2013); Herdewijn, P., et al.: Biomed. Health Res., 24, 182 (1998)

Applications Methylphloroglucinol is used for the formation of insoluble azo dyes on blended fabrics. It is also used in the synthesis of inhibitory dihydroxyxanthone derivatives that are active against human tumor cell lines.
References Tarakanova, L. et al.: Fiber Chem., 42, 254 (2011); Castanheiro, R. et al.: Bioorg. Med. Chem., 15, 6080 (2007);

Applications 2,4,6-Triacetylphloroglucinol (cas# 2161-87-7) is a compound useful in organic synthesis.

Applications Aminobutanol is used in the preparation of CDK inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, J. et al.: Chin. J. Chem., 31, 1181 (2013); Tahghighi, A. et al.: J. Enz. Inhib. Med. Chem., 28, 843 (2013);

Applications 4,4-dimethylpentan-2-ol (cas# 6144-93-0) is a useful research chemical.

Stability Light Sensitive, Volatile
Applications 1,5-Hexadien-3-ol is a reactant used in the synthesis of laurencia metabolite obtusenye.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Crimmins, M.T., et al.: J. Am. Chem. Soc., 125, 7592-7595 (2003)

Applications 3,5,5-Trimethyl-1-hexanol can be used as a fragrance material and a flavoring agent for food.
References McGinty, D., et al.: Food and Chem. Toxic., 48(Suppl. 4), S47-S50 (2010);Letizia, C. S., et al.: Food and Chem. Toxic., 38(Suppl. 3), S223-S225 (2000)

Stability Hygroscopic
Applications O-AMINOPHENOL SULFATE (cas# 67845-79-8) is a useful research chemical.

Applications 2-Butoxyethanol is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.
References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)

Applications 4-Phenoxyphenol is a porous organic material with dumbbell channels that appear throughout its structure. These channels can also host solvent molecules during crystal growth. 4-Phenoxyphenol is also part of a group of phenolic compounds that have potential apoptotic activity, which can be used in the development of new treatments for cancer therapy.
References Hansch, C., et al.: Bioorg. Med. Chem., 11, 617 (2003); Thomas, L., et al.: Cryst. Growth. Des., 12, 1746 (2012)

Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.
References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)

Applications 2-Penten-4-yn-1-Ol is a useful reagent in the silver-​catalyzed cyclization of acetylenic alcohols. It is also employed in the studies related to the field of acetylenic epoxides.
References Pale, P., et al.: Eur. J. Org. Chem., 10109 (2000); Malinovskii, M. S., et al.: Tezisy Dokl. - Vses. Konf. Khim. Atsetilena, 5, 82 (1975)

Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976)

Applications Cyclopentaneethanol is used in the prepartion of phenylalanine derivatives for incorporation into peptides as CD4 mimetic miniproteins interacting with HIV-1 surface glycoprotein. It is also used in the preparation of tertiary amine muscarinic receptor antagonists applied towards the treatment of chronic obstructive pulmonary disease.
References Morellato-Castillo, L. et al.: J. Med. Chem., 56, 5033 (2013); Glossop, P. et al.: J. Med. Chem., 54, 6888 (2011);

Applications [4-(Trimethylammonium)benzyl] Alcohol Bromide is a compound useful in organic synthesis.

Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)

Applications (±)-2-Phenylbutanol is used as a reagent in the synthesis of carbamate derivatives of Felbamate (F231000), as potential anticonvulsant agents. (±)-2-Phenylbutanol is also used to prepare analogs of O-(2-phenylethyl)-N-phenylthiocarbamate which can serve as non-nucleoside HIV-1 reverse transcriptase inhibitors.
References Kung, C., et al.: Med. Chem. Res., 19, 498 (2010); Cesarini, S., et al.: Bioorg. Med. Chem., 16, 4173 (2008)

Applications 2-amino-2-cyclopropylpropan-1-ol (cas# 1184403-67-5) is a useful research chemical.

Applications 2H-1,3-benzodithiole-2-thione (cas# 934-36-1) is a useful research chemical.

Applications Tetrahydro-2H-pyran-2-ol (cas# 694-54-2) is a useful research chemical.

Applications Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);

Applications 10-Undecen-1-ol (cas# 112-43-6) is a useful research chemical.

Applications 7N-[1-(2-Carboxy)ethyl]allopurinol (cas# 34397-00-7) is a compound useful in organic synthesis.

Applications a volatile hydroxy acid component of particular body odors
References Rogge, C., et al.: Biochem., 41, 10141 (2002), Natsch, A., et al.: Chem. Biodiversity, 3, 1 (2006), Liu, G., et al.: Biomacromol., 9, 949 (2008),

Applications 2-Aminothiophen-3-ol, is a heterocyclic building block used for the synthesis of various pharmaceutical compounds.

CCT 241533 is a Chinese herb that has been shown to have anti-cancer properties. It has been demonstrated to inhibit the growth of HL-60 cells and induce apoptosis in these cells. CCT 241533 also inhibits the proliferation of epidermal growth factor (EGF) and induces cell death in response to radiation. This drug also binds to toll-like receptors, which are proteins on the surface of cells that detect pathogens and initiate an immune response. CCT 241533 has been shown to inhibit polymerase chain reactions by competitive inhibition or by binding to DNA, preventing transcription or replication. CCT 241533 may be useful for the treatment of infectious diseases, such as tuberculosis, because it can bind to bacterial 16S ribosomal RNA and inhibit protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.
CCT 241533 has been shown in animal studies to be effective against cervical cancer due to its ability to bind

Chromagnol is a drug that inhibits the enzyme protein kinase C (PKC). It has been shown to have inhibitory properties on cardiac muscle cells and whole-cell recordings of heart cells. Chromagnol has also been shown to affect the function of bowel disease, including papillary muscle. Chromagnol has been shown to have effects on cardiac and atrial tissue. This drug may be a potential treatment for autoimmune diseases, such as multiple sclerosis, or other diseases that are caused by PKC overactivity. The mechanisms of action are not fully understood but it is believed that chromanol binds to the cytosolic Ca2+ ion channel, preventing it from opening and releasing Ca2+, which leads to an increase in intracellular Ca2+.

2H-1,2,3-Triazol-4-ylmethanol is an aliphatic hydrocarbon that can be synthesized by reacting chlorine with a hydroxy group. It has been shown to have insecticidal activity against flies and mosquitoes. 2H-1,2,3-Triazol-4-ylmethanol is also used as a precursor for the synthesis of triazole derivatives. These compounds are used in the production of pharmaceuticals and pesticides. 2H-1,2,3-Triazol-4-ylmethanol also has neurodegenerative disease activities. This compound may be useful in treating diseases such as Alzheimer's disease or Parkinson's disease because it inhibits the formation of beta amyloid proteins that are linked to these conditions.

4-Hydroxy-7-methoxyquinoline is an anti-malarial drug that belongs to the class of trimethyl, trifluoromethyl group. It is a cyclic compound and its synthesis starts with cyclization of the methyl derivative, which forms a ring. This product is used in clinical practice as an inhibitor of malarial protozoa and has been shown to have mechanistic effects on the cytochrome bc1 complex containing red blood cells. 4-Hydroxy-7-methoxyquinoline also inhibits the growth of bacteria by binding to the enzyme methionine synthase, which is involved in the biosynthesis of methionine from homocysteine. The product also has an inhibitory effect on DNA synthesis and protein synthesis.

3-Buten-2-ol is an organic compound that contains a hydroxyl group and a double bond in the form of an alkene. It is a colorless liquid with a sweet odor. 3-Buten-2-ol is used as a chemical intermediate to produce glycol ethers, which are used as solvents for paints and coatings. 3-Buten-2-ol has been shown to inhibit protein synthesis by inhibiting glutamate dehydrogenase, which is required for the conversion of glutamate to α-ketoglutarate in the TCA cycle. The deuterium isotope effect on the kinetic data suggests that 3-buten-2-ol binds to the active site of glutamate dehydrogenase and blocks its access to substrate.

Rac-1,2-bis-palmitoyl-3-chloropropanediol is a dispersive molecule that is composed of a fatty acid and a chlorinated derivative of palmitic acid. It is used to calibrate the mass spectrometer and as an internal standard in quantitative analysis. Rac-1,2-bis-palmitoyl-3-chloropropanediol reacts with electrospray ionization with a dose-dependent response. It has been shown to be toxic to kidney cells at high doses but not at low doses. This chemical has been detected in food samples after being absorbed from the gastrointestinal tract. Rac 1,2-bis-palmitoyl 3 chloropropanediol can be found in the dipalmitate form or as formic acid.

Please enquire for more information about 4-Aminotetrahydrothiophene-3-ol 1,1-dioxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

T2 toxin triol is a bacterial strain that is used as a model system for the study of zearalenone. It has been shown to inhibit the growth of trifluoroacetic acid-treated cells and prevent the formation of glucuronide conjugates. T2 toxin triol has also been shown to be toxic to rat liver microsomes in vitro, but not to tissue culture or monoclonal antibody-transfected cells. The toxicity was found to be due to its basic structure, which causes an increase in intracellular levels of reactive oxygen species and lipid peroxidation.

Please enquire for more information about (20R)-Pregn-4-ene-3,17,20-triol including the price, delivery time and more detailed product information at the technical inquiry form on this page

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