Álcoois

Applications 4-​Bromo-​3-​methyl-2-buten-1-ol is an intermediate in the synthesis of 2-[(4-Bromo-3-methyl-2-buten-1-yl)oxy]tetrahydro-2H-pyran (B681855), which is a tetrahydropyran protected intermediate used in the synthesis of L-Cysteine derivatives.

Applications Bromo-tert-butyl Alcohol, is an organic building block that can be used in the variety of chemical synthesis. It is used in the synthesis of Monohalogeno-t-butyloxycarbonylamino Acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Takanobu, O. et al.: Bull. Chem.Sco. Jap., 45, 2603 (1972);

Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)

Applications 4-Amino-2-isopropylphenol is a building block used in the preparation of benzoate and benzamide derivatives as FXR antagonists.
References Song, K., et al.: Bioorg. Med. Chem., 23, 6427 (2015);

Stability Light Sensitive
Applications cis-1,5-Octadien-3-ol is an intermediate in the synthesis of (Z)-Octa-1,5-dien-3-one (O235830), which is an odorant found in green tea, and palm wines.
References Katsuno, T., et. al.: Food Chem., 148, 388 (2014); Lasekan, O.: Molecules, 18, 11809 (2013)

Applications 4-(phenylsulfanyl)phenol (cas# 5633-55-6) is a useful research chemical.

Applications 3,5,5-Trimethyl-1-hexanol can be used as a fragrance material and a flavoring agent for food.
References McGinty, D., et al.: Food and Chem. Toxic., 48(Suppl. 4), S47-S50 (2010);Letizia, C. S., et al.: Food and Chem. Toxic., 38(Suppl. 3), S223-S225 (2000)

Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976)

Applications 2-(Ethylamino)ethanol is used in the preparation of novel indole-2-carboxamide and 3-acetamide derivatives as antioxidant protective agents. Also used in the synthesis of novel amino acid based arginase inhibitors used towards the treatments of myocardial ischemia reperfusion injury.
References Oelgen, S. et al.: J. Enz. Inhib. Med. Chem., 28, 58 (2013); Van Zandt, M. et al.: J. Med. Chem., 56, 2568 (2013);

Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.
References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);

Applications 2-(Tetrahydro-2H-pyran-3-yl)ethanol (cas# 1050493-77-0) is a useful research chemical.

1H-Pyrazol-4-ol is a molecule that has been shown to have antibacterial properties by inhibiting the growth of bacteria. It was also found to be effective in inhibiting the activity of dopamine β-hydroxylase, which is an enzyme that catalyzes the conversion of dopamine to norepinephrine. 1H-Pyrazol-4-ol has been shown to inhibit nitrite ion reductase, which converts nitrite ions into nitric oxide. Nitric oxide is a potent vasodilator and can cause hypotension. 1H-Pyrazol-4-ol also inhibits the formation of nitro groups from diazonium salts, which are used in many industrial processes, including dyeing and photography. 1H-Pyrazol-4-ol is activated by UV light and reacts with epididymal adipose tissue (fatty tissue) in rats to generate pyrazole derivatives with cytotoxic effects on liver

4-Hydroxy-3-nitro-2(1H)-quinolinone is a quinoline derivative that has been shown to have anticancer activity against cancer cells. It can be used for the treatment of various types of cancer, including lung cancer, breast cancer, and colon cancer. This drug inhibits the growth of cancer cells by blocking the cycle at the G1 phase and inducing apoptosis. It also disrupts mitochondrial membrane potential, leading to an increase in reactive oxygen species and DNA damage. 4-Hydroxy-3-nitro-2(1H)-quinolinone is an epidermal growth factor receptor (EGFR) antagonist and blocks epidermal growth factor signaling through its inhibition of EGFR tyrosine kinase activity. It also downregulates TNFα expression in tumor cells by inhibiting NFκB activation.

Estra-1,3,5(10),6-tetraene-3,17-diol is a sulfonated derivative of estradiol. It is used as a ligand in binding assays to measure the affinity of various compounds for estrogens. Estra-1,3,5(10),6-tetraene-3,17-diol binds with high affinity to 17β-estradiol and other estrogens at the estrogen receptor. The binding of estradiol and its derivatives to the receptor leads to a conformational change that causes dissociation of heat shock proteins from the receptor. This results in an increase in transcriptional activity of the receptor and increased synthesis of mRNA.

(R)-1-Phenylethanol is an organic compound that belongs to the class of aldehydes. It has an optimal redox potential and is used as a reactive intermediate in surface methodology. The kinetic data for this compound have been reported, including its reaction solution, kinetic, and stereoselective properties. (R)-1-Phenylethanol can be used to synthesize aromatic hydrocarbons with acyl chains or amines, using enzymatic reactions. It can also be used as an asymmetric synthesis reagent for the preparation of chiral alcohols and amines.

2,6-Dibromophenol is a chemical compound that is used as an analytical reagent in the determination of bromide ion concentrations. It can be prepared by the debromination of 2-bromophenols using hydrochloric acid and heating to 150°C. This reaction mechanism is best described by kinetic data and a model system. The reaction product of this process is 2,6-dibromo-3-hydroxyphenol. This compound has been shown to have a higher dry weight in strains with high levels of hydroxy group activity.

a-Butylpiperonyl alcohol is a chiral molecule that is used in the synthesis of esters. It can be produced by microbial fermentation and low-temperature chemical reactions. This compound has been shown to inhibit the growth of Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae. The biosynthetic pathway for a-butylpiperonyl alcohol is not yet well understood, but it has been hypothesized that this compound is synthesized from an intermediate, acetic acid. The enzyme responsible for this conversion is unknown, but it may be catalysed by an acylase or acetate kinase. A study on the genome sequence of Coelicolor revealed that this organism produces a-butylpiperonyl alcohol from the intermediate 3-hydroxypropanoic acid.

5-Benzofuranol is a potent cytotoxic natural product that has been isolated from the fungus Cryptococcus neoformans. It possesses a terminal alkyne group and a sulfonic acid group, which are both important for its cytotoxicity. 5-Benzofuranol inhibits the growth of cells in vitro by inhibiting their ability to synthesize DNA. 5-Benzofuranol shows significant cytotoxicity against various cancer cell lines, as well as potent inhibition against Candida albicans, Aspergillus niger, and Saccharomyces cerevisiae strains in vitro. This compound's functional groups make it an effective antifungal agent.

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2H-1,2,3-Triazol-4-ylmethanol is an aliphatic hydrocarbon that can be synthesized by reacting chlorine with a hydroxy group. It has been shown to have insecticidal activity against flies and mosquitoes. 2H-1,2,3-Triazol-4-ylmethanol is also used as a precursor for the synthesis of triazole derivatives. These compounds are used in the production of pharmaceuticals and pesticides. 2H-1,2,3-Triazol-4-ylmethanol also has neurodegenerative disease activities. This compound may be useful in treating diseases such as Alzheimer's disease or Parkinson's disease because it inhibits the formation of beta amyloid proteins that are linked to these conditions.

3-Buten-2-ol is an organic compound that contains a hydroxyl group and a double bond in the form of an alkene. It is a colorless liquid with a sweet odor. 3-Buten-2-ol is used as a chemical intermediate to produce glycol ethers, which are used as solvents for paints and coatings. 3-Buten-2-ol has been shown to inhibit protein synthesis by inhibiting glutamate dehydrogenase, which is required for the conversion of glutamate to α-ketoglutarate in the TCA cycle. The deuterium isotope effect on the kinetic data suggests that 3-buten-2-ol binds to the active site of glutamate dehydrogenase and blocks its access to substrate.

L-phenylglycinol is a chiral compound that is synthesized by the reaction of phenylglycinol with hydroxide solution in the presence of an asymmetric synthesis catalyst. It is used as a precursor to chiral amides and aziridines, which are important for addressing the need for enantiopure compounds. The reaction mechanism involves nucleophilic substitution at the amino function, which can be catalyzed by copper complexes in solution. This reaction can also be monitored using liquid chromatography methods.

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4-Aminoquinoline-2-one is a nonsteroidal anti-inflammatory drug that has tuberculostatic activity. It binds to the nitrogen atoms of the enzyme dihydropteroate synthase, which is involved in the synthesis of folic acid and DNA. This leads to an increase in reactive oxygen species and inflammation, which causes disease activity. 4-Aminoquinoline-2-one has been shown to be synergistic with monoclonal antibodies when used as a treatment for inflammatory diseases. In order for 4-aminoquinoline-2-one to be taken up by cells, it must bind to cellular uptake proteins through hydrogen bonds or disulfide bonds.

1-ethynyl-cyclohexan-1-ol is a silicon sealant that can be used in a variety of industries. 1-ethynyl-cyclohexan-1-ol has high resistance to water, oil and other chemical substances. 1-ethynyl-cyclohexan-1-ol is a molecule with the formula CH2CH(OH)CH2 and it is not soluble in water. It is also chemically stable and does not react with hydrochloric acid. The FTIR spectra show that the carbonyl group in 1-ethynyl cyclohexanone is present as an ester. The nmr spectra indicate that the substrate film contains methyl ethyl silicone and that there are no other components present.

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4-Methylquinoline is a natural compound that is structurally related to coumarin. It serves as an enzyme substrate for various types of enzymes, and has been shown to inhibit the activity of enzymes such as N-acetyltransferase, indoleamine 2,3-dioxygenase, and tryptophan 2,3-dioxygenase. 4-Methylquinoline has also been shown to be effective against infectious diseases such as toxoplasmosis and leishmaniasis. Furthermore, 4-methylquinoline has been shown to have anti-inflammatory properties in autoimmune diseases such as multiple sclerosis. The mechanism of action of 4-methylquinoline is not fully understood but it may interfere with the production of nitric oxide by inhibiting the enzyme nitric oxide synthase.

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4-Pregnen-17a,20b-diol-3-one is a synthetic androgen with anabolic and androgenic activity. It has been shown in animal studies to increase maximal responses of the reproductive tract to gonadotropin stimulation. 4-Pregnen-17a,20b-diol-3-one binds to the activin receptor on the cell membrane, which leads to increased expression of a gene encoding for 3β-hydroxysteroid dehydrogenase (3βHSD), an enzyme involved in testosterone synthesis. This drug also increases the sensitivity of ovarian follicles to gonadotropins and decreases basal plasma levels of LH and FSH. 4-Pregnen-17a,20b-diol-3-one has not been found to be toxicologically significant at doses up to 10 mg/kg body weight per day.

R-(-)-1,2-Propanediol is a diol that is used as an additive in pharmaceutical preparations. It has been shown to inhibit the growth of several genera of bacteria and fungi, including Actinomyces, Bacillus, Clostridium, Corynebacterium, Enterobacteriaceae (Escherichia coli), Lactobacillus, Micrococcus, Mycobacteria (M. tuberculosis), Nocardia, Pseudomonas aeruginosa. R-(-)-1,2-Propanediol also inhibits the production of carbon source from glucose by inhibiting the enzyme pyruvate dehydrogenase which catalyzes the conversion of pyruvate to acetyl coenzyme A. R-(-)-1,2-Propanediol does not show any significant effect on bacterial growth when it is used at concentrations below 100mM. It has been shown that optimal reaction with R-(-)-

Dibromochloromethane (DBCM) is a chemical that is used as a solvent and cleaning agent. It was found to be genotoxic, with the potential to cause cancer in humans. DBCM causes cardiac effects in animals, including arrhythmias and an increase in heart rate. DBCM is not volatile and has a low vapor pressure, which makes it hazardous if inhaled or ingested. DBCM can also cause renal toxicity and liver injury in rats. Dibromochloromethane has been shown to have a toxic effect on the heart, lungs, kidneys and liver when administered at high doses in animals. It has been shown to damage DNA by causing mutations or cross-linking with DNA strands.

2-(1-Adamantyl)propan-2-ol is an alcohol that can be synthesized in a multistep process. This molecule has been shown to inhibit the influenza virus, which is a type of negative strand RNA virus. It reacts with the sulfide group on the influenza virus, forming a covalent bond. The structure of 2-(1-Adamantyl)propan-2-ol is similar to that of amantadine and azetidine, which are also antiviral drugs used for the treatment of influenza.

2-[(4-Methylbenzenesulfonyl)oxy]ethan-1-ol is a compound that contains a benzene ring and an ethyl chain. It has the following chemical structure: It is structurally related to benzodiazepine, but with an amide group instead of a diazepine ring. 2-[(4-Methylbenzenesulfonyl)oxy]ethan-1-ol is a membrane stabilizer that inhibits thrombin and can be used as an anticoagulant. This compound also has growth factor activity and can be used in the synthesis of heterocyclic compounds.

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4-Cinnolinecarboxaldehyde is an organic compound that belongs to the group of cinnoline. It is a colorless liquid that can be used as a precursor in the production of aluminum metal. 4-Cinnolinecarboxaldehyde reacts with lithium aluminum hydride to form a compound that can be used as a reducing agent in organic chemistry. 4-Cinnolinecarboxaldehyde is also used as a precursor for preparing other compounds, such as lithium aluminum hydride and lithium aluminum trihydride.

RITA is a novel compound that has been shown to have anticancer activity in vivo in a rat model. RITA is a small molecule with high potency and low toxicity. It binds selectively to the α subunit of the enzyme topoisomerase II, which is involved in DNA replication and repair. RITA has been shown to induce apoptosis in cancer cells by pro-apoptotic proteins such as Bax and Bak. These proteins are known for their ability to induce apoptosis by increasing mitochondrial membrane permeability, inhibiting mitochondrial functions, or destabilizing the mitochondrial membrane potential. The compound class of RITA is not yet known, but it has been shown to be chemically stable at physiological pH levels and does not require metabolic activation for its cytotoxicity. The pharmacokinetics of this drug have also been studied in human liver cells and humans, indicating that this drug may be able to cross the blood-brain barrier.

3-Methyl-1-pentyn-3-ol is a chemical that has been shown to have interactive effects on the metabolism of urea nitrogen and low light. 3-Methyl-1-pentyn-3-ol has been shown to produce a depressant effect in animals, which may be due to its ability to inhibit the production of acetylcholine by blocking the enzyme cholinesterase. This chemical has also been shown to react with hydroxyl groups, producing a pharmacological agent. The reaction mechanism for 3-methyl pentynol is via hydrolysis by hydrochloric acid or pentobarbital sodium.

3-Phenyl-1-propanol is an organic compound that belongs to the class of trifluoroacetic acids. It has a molecular weight of 134.24 and a molecular formula of C8H12O2F3. 3-Phenyl-1-propanol is a reactive compound that reacts with germinating seeds, causing them to stop growing. The reaction products are fatty acid esters, which may be responsible for the inhibition of seed germination. 3-Phenyl-1-propanol can be prepared by reacting phenylacetaldehyde with trifluoroacetic acid in the presence of potassium hydroxide at high temperature and pressure. This method also produces 4-vinylbenzyl alcohol as a side product, which is used in the production of polymers and plastics.

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