Álcoois

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethanol is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

2-Chlorophenyl)diphenylmethanol is an antifungal drug that blocks the function of a calcium ionophore in fungal cells. It has been shown to be effective against a variety of filamentous fungi, including Aspergillus fumigatus, Candida albicans, and Trichosporon cutaneum. This drug is used as a topical antifungal agent for treatment of skin infections caused by these fungi. 2-Chlorophenyl)diphenylmethanol has been shown to have anti-inflammatory properties in animal models of kidney fibrosis and cell binding. Clinical data suggests that it can be used for the prevention or treatment of stem cell transplantation complications such as graft versus host disease and leukemia.

Phenyl ethyl alcohol is a chemical compound that is used as an antiseptic. It is also known for its ability to reduce the surface tension of water, which makes it useful for cleaning and degreasing. Phenyl ethyl alcohol has been shown to be up-regulated in genes that are responsible for transcriptional regulation, as well as in genes that encode proteins involved in cellular metabolism. This compound has been used as a model system to study hydrogen bonds and biological samples. The structural biology of phenyl ethyl alcohol has been studied using detergent compositions and fatty acid models.

Trichloroethanol is an alkanoic acid that is used as a solvent and a laboratory reagent. It is also a potential bioactive compound. Trichloroethanol has been shown to have neurotoxic effects in rats, causing histological changes in the trigeminal nerve, which may be due to its inhibition of mitochondrial energy metabolism. Trichloroethanol has been shown to inhibit the activity of matrix metalloproteinase-9 (MMP-9) in human serum and the α1 subunit of Toll-like receptor (TLR) 4 in human monocytes. This compound has also been shown to be toxic to rat liver microsomes at high concentrations.

1-O-Octadecyl-rac-glycerol is a fatty acid that has been shown to have antiinflammatory properties. It is also known as 1,1'-dioctadecyl-rac-glycerol, or DOG. 1-O-Octadecyl-rac-glycerol has been shown to inhibit the production of inflammatory mediators such as prostaglandin E2 and monocyte chemotactic protein 1 (MCP1) in vitro and in vivo. It has also been shown to stimulate the production of colony stimulating factor (CSF), which stimulates the growth and differentiation of stem cells into macrophages, neutrophils, dendritic cells, erythrocytes, and lymphocytes. These cells are needed for wound healing and repair.

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Quinoline-4-carboxylic acid is a natural compound that is derived from the amino acid tryptophan. It has been shown to have antiinflammatory activity and to be an inhibitor of prostaglandin synthesis. Quinoline-4-carboxylic acid inhibits the growth of carcinoma cells in culture by inducing apoptosis, which is mediated by inhibition of protein synthesis. Quinoline-4-carboxylic acid also has pharmacokinetic properties, including a low volume of distribution, low clearance rate and high bioavailability.

Product FB158451, cis, trans-2-Buten-1,4-diol, is a versatile chemical compound with the CAS number 110-64-5. It is used a key building block in various chemical synthesis processes, making it an essential component for researchers and industrial applications. Its versatile nature allows it to be employed in the production of polymers, resins, and specialty chemicals, making it a valuable asset for a wide range of applications.

Methallyl alcohol is a reactive hydroxide solution that is used as an intermediate in the industrial synthesis of polycarboxylic acids, glycol ethers, and other compounds. It reacts with hydrogen chloride to form methallyl chloride, which can be used to produce polymers. Methallyl alcohol can also be used as a reagent for the synthesis of various esters, amides, and other organic compounds. The enzyme inhibitors it produces inhibit reactions involving fatty acid and aliphatic hydrocarbon oxidation. Methallyl alcohol is produced by the reaction of methanol with allyl chloride. This reaction occurs in vivo under acidic conditions.

Calcipotriol is a synthetic vitamin D3 analog that has been shown to be effective in the treatment of bone cancer. It has a film-forming property and is used in pharmaceutical preparations as well as for wastewater treatment. Calcipotriol monohydrate is made by reacting calcipotriol with hydrochloric acid, which produces an ester bond between the hydroxyl group and the carboxylic acid group. The reaction also produces water, methanol, and methyl ethyl ether. Studies have shown that calcipotriol monohydrate has a chemical stability of over 30 days at room temperature, indicating it can be stored for long periods without degradation.

3,3-Dimethyl-1,2-butanediol is a dioxolane with a constant boiling point of 110°C. This compound is synthesized from the reaction between acetone and formaldehyde, which produces a dioxolane ring. The reaction products can be profiled using gas chromatography to determine the ratio of each product. 3,3-Dimethyl-1,2-butanediol has been shown to have enantiomeric purity of greater than 99%. It has also been used as a chiral building block for the synthesis of carbohydrates with stereospecificity. 3,3-Dimethyl-1,2-butanediol's enzyme catalysis is used in the production of polyesters and polyurethanes.

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5-Chloro-8-hydroxyquinoline (5-CQ) is a quinoline derivative that has been used as an anticancer agent. It binds to DNA and inhibits the synthesis of RNA and proteins, leading to cell death. 5-CQ has been shown to be cytotoxic against skin cells in vitro by inhibiting mitochondrial oxidative phosphorylation and decreasing the mitochondrial membrane potential. This compound also has genotoxic effects on cultured choroidal neovascularization cells through the inhibition of DNA synthesis.
5-CQ binds to DNA via hydrogen bonds with nitrogen atoms in the purine ring of nucleobases. The overall geometry is that of a distorted octahedron with two faces, each containing six nitrogens in square planar coordination geometry. The binding constants are low for purines but high for pyrimidines, which is why 5-CQ preferentially targets purine rich regions of the genome.

2-Dimethylaminoethanol (+)-bitartrate salt is a potent, reversible inhibitor of protein synthesis that binds reversibly to the 50S ribosomal subunit. It is used in regulatory toxicology and clinical pathology as a positive control for the study of chronic toxicity and long-term effects. 2-Dimethylaminoethanol (+)-bitartrate salt has shown no treatment effect on ovary weight or estrous cycle length in female Sprague-Dawley rats after chronic exposure and long-term exposure at doses up to 1,000 mg/kg/day. This drug has also shown no effect on rat fertility or reproductive performance, indicating it does not cause reproductive toxicity.

3,4-Diethoxybenzylalcohol is a metabolite produced by the fungus Ustilago maydis. It has been shown to have pleiotropic effects on the metabolism of the organism. 3,4-Diethoxybenzylalcohol is involved in lignin biosynthesis and bond cleavage reactions. In addition to functioning as an intermediate in the pentose phosphate pathway, it is involved in the nature of the basidiomycete cell wall and also plays a role in carbon source utilization.

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