Aminas

<p>Applications 5-Chloropyridazin-3-amine is an intermediate used to prepare aminopyrazines as novel, potent Nav1.7 antagonists.<br>References Bregman, H., et al.: Bioorg. Med. Chem. Lett., 22, 2033 (2012)<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo xy peptidase, plasmin, and plasminogen activator.<br>References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),<br></p>

<p>Applications 2-Dimethylaminoethyl Benzilate is an intermediate in the synthesis of Propinox (P771500), an antispasmodic agent used in the treatment of moderate to severe colic pain of biliary origin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mishra, R., et al.: Pharma. Chemica., 2, 185 (2010);<br></p>

<p>Applications Methyl 4-aminosalicylate<br></p>

<p>Applications Oleylamine is a surfactant in the synthesis of nanoparticles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is used for preparation of glutamic acid-containing acylating reagents for selective acylation of amino group(s) in peptides or proteins.<br>References Christensen, C., et al.: PCT Int. Appl. (2010), WO 2010084169 A2 20100729.<br></p>

Carboprost tromethamine is a synthetic prostaglandin analogue that is used to induce labor in pregnant women. Carboprost tromethamine has minimal toxicity and can be combined with other drugs to improve efficacy. This drug has been shown to be effective in combination therapy groups, with minimal side effects. Carboprost tromethamine inhibits the activity of the enzyme phospholipase A2, which is responsible for the breakdown of fatty acids and production of inflammatory mediators. It also has anti-inflammatory properties and can be used as a treatment for metabolic disorders such as bladder dysfunction. Carboprost tromethamine is not active against bacteria or fungi, but it does have some antibacterial properties that may come from its ability to inhibit bacterial rRNA synthesis at high concentrations. Carboprost tromethamine should not be used during pregnancy or breastfeeding due to its potential risk of uterine contractions after childbirth, which can interfere with placental

3-Amino-2-methylquinazolin-4(3H)-one is a bidentate ligand that has been shown to have antibacterial and anticancer activity. The functional theory of the compound is based on its ability to form an imine nitrogen with metal ions such as Fe(II) or Cu(II). 3-Amino-2-methylquinazolin-4(3H)-one is not active against Staphylococcus aureus, but inhibits the growth of other bacteria by binding to their ribosomes and inhibiting protein synthesis. 3-Amino-2-methylquinazolin-4(3H)-one also has in vitro anticancer activity, which may be due to its ability to inhibit DNA synthesis and cell division.

(2R)-1-[2-[(3-Hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile is a drug that belongs to the class of DPP-IV inhibitors and is used for the treatment of type 2 diabetes mellitus. It has been shown to be effective in reducing postprandial blood glucose levels in patients with type 2 diabetes mellitus. The mechanism of action of this drug is not fully understood, but it may have an effect on insulin release from pancreatic beta cells and/or inhibition of gastric emptying or intestinal absorption of glucose. This drug has been shown to reduce tubulointerstitial injury in diabetic rats and can be used as a combination therapy for type 2 diabetes mellitus. There are no known clinically relevant interactions between (2R)-1-[2-[(3-Hydroxytricyclo

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<p>Please enquire for more information about Pravastatin 1,1,3,3-tetramethylbutylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>4-Aminobenzenesulfonic acid is a sulfonic acid that is used in wastewater treatment. It has been shown to be an excellent water permeability agent and can be used as an additive to the process of making sulfonated polymers for use in water filtration. 4-Aminobenzenesulfonic acid has been shown to have enzyme inhibitory effects on metal hydroxide-dependent enzymes, such as sulphanilic and sulfanilic acid. This compound also has been investigated as a potential therapeutic agent for the treatment of cancer, with some success. It has been shown to stimulate the production of picolinic acid, which is an intermediate in the kynurenine pathway leading to production of nicotinamide adenine dinucleotide (NAD+). In humans, 4-aminobenzenesulfonic acid can bind toll-like receptors (TLRs) and activate TLR4 signaling pathways.</p>

<p>Dinonylamine is an industrial chemical that is used as a solvent for waxes and resins. It has been used as a substrate film for the production of polycarbonate plastics and in the manufacture of amines, nitroaromatic compounds, and fluoropolymers. Dinonylamine has been shown to have an inhibitory effect on the growth of microorganisms by reacting with their aromatic hydrocarbons. This chemical reacts with carbonyl groups to form hydroxyl groups, which are toxic to bacteria. It also reacts with radiation to form a patterned surface that can be used to immobilize enzymes or other proteins.br&gt;br&gt; br&gt;br&gt; Dinonylamine is used in industrial processes as a precursor for amines and hydroxy groups, which are important components in many organic molecules including pharmaceuticals. These reactions take place in solvent vapor phase reaction vessels at high temperatures.br&gt;br&gt; br&gt;br&gt; Din</p>

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<p>N-Nitroso-di-n-butylamine is a nitrosamine that is a product of wastewater treatment. It has been shown to inhibit mitochondrial function and induce liver lesions in rats at high doses. N-Nitroso-di-n-butylamine is structurally similar to the natural substrate ribose, which leads to inhibition of xanthine oxidase, an enzyme involved in purine metabolism. The structural analysis revealed the presence of reactive sites that are susceptible to attack by nucleophiles, such as hydroxyl radicals or hydrogen peroxide. This indicates that N-Nitroso-di-n-butylamine may be a precursor for other carcinogenic compounds. NADH is reduced by NADH dehydrogenase (complex I) in mitochondria to produce NAD+, which subsequently donates electrons to the electron transport chain and generates ATP. The ability of NNDB to inhibit complex I activity was assessed using hl60</p>

Dioleoyloxypropyl-N,N,N-trimethylammonium methylsulfate (DOTAP) is an antibacterial agent that disrupts the bacterial membrane. It has been shown to inhibit the uptake of chlamydia by inhibiting the binding of chlamydia to cells and enhancing the detection of chlamydia in cells. DOTAP also has pharmacological properties that are related to its ability to interfere with cellular membranes. DOTAP can be used as a strategy for developing antibacterial agents because it inhibits bacterial growth by disrupting their cellular membranes. This results in a decrease in phosphatidylethanolamine levels, leading to increased cell death.

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Alanine,n,N'-[[5-[2-amino-5-(2,2-dimethyl-1-oxopropyl)-4-thiazolyl]-2-furanyl]phosphinylidene]bis[2-methyl-,1,1'-diethylester] is a metabolic inhibitor that is used in the treatment of type 2 diabetes. It inhibits gluconeogenesis by inhibiting the enzyme phosphoenolpyruvate carboxykinase (PEPCK), which catalyzes the conversion of oxaloacetate to phosphoenolpyruvate. This compound has been shown to reduce fasting blood glucose levels in diabetic animals and humans.

<p>4-Amino-3-bromo-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidine is a drug that inhibits the growth of tumour cells by binding to and inhibiting kinases. It has been shown to have a significant inhibitory effect on lung cancer cells and pyridazine derivatives in vitro. 4-Amino-3-bromo-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidine has been shown to be effective against lung cancer cells in vivo. This drug may be useful for the treatment of cancer.</p>

<p>Please enquire for more information about 2-Methoxy-4-amino-5-ethylthiobenzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,2,4-Triazin-5-amine is a synthetic compound that has been shown to have significant activity against the enzyme carbonyl reductase. The term "significant" refers to the inhibition of this enzyme by 1,2,4-triazin-5-amine in a dose dependent manner. This inhibition was observed with allosteric inhibitors and orthosteric inhibitors. 1,2,4-Triazin-5-amine has also been shown to be effective in inhibiting phosphatases and butyric acid hydrolase in vitro. The mechanism of 1,2,4-triazin-5-amine is unknown but it is thought that it may act as an inhibitor of human diseases such as Alzheimer's disease or Parkinson's disease.</p>

<p>4-Methoxybenzylamine is an organic amine that has a redox potential of -0.14 V (vs. SHE) and a pK a of 10.5. It is used in the synthesis of trifluoroacetic acid esters, which are used as pharmaceutical intermediates. 4-Methoxybenzylamine has been shown to be effective in alleviating pain in animal models, and its mechanism of action may be due to inhibition of the enzyme cyclooxygenase. The kinetic data for this reaction were obtained by studying the deuterium isotope effect, which is characterized by a low energy barrier and rapid reaction rate. The hydrolysis step is also important for the reaction mechanism, with protocatechuic acid being an intermediate product. Hydrochloric acid is needed for dehydration of the reactants, while an aryl halide can be used instead in some cases. In these reactions, there are many possible reaction</p>

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<p>Please enquire for more information about [(1,4-Dimethyl-1H-benzimidazol-2-yl)methyl]amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-Butyl 3-(cyclopropylamino)azetidine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>2-(2-Methoxyphenoxy)ethylamine base is an inorganic base with a hydroxyl group. It is soluble in organic solvents and has been used as a coumarin derivative. 2-(2-Methoxyphenoxy)ethylamine base has shown potential use as an antifungal agent, which may be due to its ability to cause lysis in fungi cells. This compound has also shown in vitro activity against bacteria and viruses, including herpes simplex virus type 1 and HIV-1. The 2-(2-methoxyphenoxy)ethylamine base can be sulfonated or acid catalyzed to produce other derivatives that have potential use as anti-inflammatory or analgesic agents.</p>

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Pyridin-4-ylmethanamine is a chemical compound that contains a pyridine ring and an amine (-NH2) group. It is usually used as a building block for the synthesis of other compounds. Pyridin-4-ylmethanamine can be synthesized from picolinic acid, which is obtained through a reaction with sodium hydrochloride in an alkaline solution. This reaction proceeds via two steps: first, the formation of a pyridinecarboxylic acid ester and then the addition of ammonia to form pyridin-4-ylmethanamine. The transfer reactions that occur during this process are highly dependent on temperature and pH. The frequency shift effect can be observed when pyridin-4-ylmethanamine interacts with amines, which changes its absorption spectrum.

Dihydroergotamine mesylate is a medication that is used in the treatment of migraines. It belongs to the group of drugs called ergot alkaloids and has been shown to have high values in cerebral metabolism. Dihydroergotamine mesylate has also been shown to have an effect on dopamine levels in human serum, which may be due to its ability to inhibit neuronal death. Dihydroergotamine mesylate is administered intravenously, orally or intramuscularly for the treatment of acute migraine attacks. The drug can also be given rectally for the prevention of chronic migraine episodes. This drug may cause side effects such as nausea, vomiting and dizziness.

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3-Aminopropyltrimethoxysilane is a chemical that belongs to the group of aminopropyltriethoxysilanes. It is a reactive substance and is commonly used as an additive in adhesives and sealants. 3-Aminopropyltrimethoxysilane has been shown to be an efficient coupling agent for the formation of hydroxyl groups on nanoparticles, which are then used as drug carriers. The optimum concentration of 3-aminopropyltrimethoxysilane lies between 0.01 and 0.1 M, with a pH range of 6 and 8. This chemical can react with hydrochloric acid, resulting in the production of hydrogen gas; with cervical cancer cells in culture, leading to cell death; or with skin cells, causing damage to their transport properties.

3-Amino-5-methoxybenzoic acid is a macrocyclist, which means that it can switch between two different forms. When the temperature is below 27 degrees Celsius, it exists as a mesomorphic phase and when the temperature increases above 27 degrees Celsius, it exists as an isotropic phase. 3-Amino-5-methoxybenzoic acid also has homologues that are also mesomorphic or isotropic depending on their temperatures. The chemoenzymatic parameters of the two phases are different and so are their lamellar morphologies. The fluorine atom in 3-amino-5-methoxybenzoic acid makes it act like a Lewis acid, decreasing its melting point and increasing its vapor pressure. There are two isomers of 3-amino-5-methoxybenzoic acid: dodecyl and octadecyl 3--amino--5--methoxyben

Fmoc-trans-4-(aminomethyl)cyclohexane-1-carboxylic acid is a synthetic amino acid that has been shown in vitro to inhibit the growth of prostate cancer cells. It is an analog of butyric acid, a naturally occurring fatty acid. Fmoc-trans-4-(aminomethyl)cyclohexane-1-carboxylic acid has been synthesized by solid phase methods and labeled with radiotracers such as indium 111 or technetium 99m. The use of Fmoc-trans-4-(aminomethyl)cyclohexane-1-carboxylic acid in vivo is limited by its short circulating half life, rapid metabolism, and high toxicity.

4-Amino-3-bromoisoquinoline is an isocyanide that reacts with nucleophilic heteroatoms such as the amino group. It also reacts with bromine to form a bromopyridine. The nitrile group of 4-amino-3-bromoisoquinoline can be reduced with sodium borohydride to produce 4-aminoquinoline. This compound has shown potential for use in chemotherapy and treating bacterial infections.

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<p>Please enquire for more information about 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(1H-Indol-5-yl)ethanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Picolinic acid is a product of the reaction between sodium salts and tetrabutylammonium hydroxide. It has been shown to have anti-inflammatory properties in chronic arthritis patients and may be due to its ability to inhibit the production of prostaglandins. Picolinic acid also has been shown to inhibit the growth of bacteria, including Mycobacterium tuberculosis, by preventing protein synthesis. The analytical method for picolinic acid is electrochemical impedance spectroscopy with a 5% picolinic acid solution in human serum or other biological sample.</p>

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(1,3-Dimethylbutyl)amine is a chemical substance that can be found in dietary supplements. It is structurally similar to amines and has been shown to have an effect on blood pressure. (1,3-Dimethylbutyl)amine has also been reported as being used in the manufacture of medicines for the treatment of heart disease. This chemical substance is produced by the reaction of hydrochloric acid with isovaleric acid. The product is then purified by chromatography and converted into its salt form for use as a dietary supplement. In addition to this, (1,3-Dimethylbutyl)amine is also used in some herbal remedies.

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Fluoxetine is a potent inhibitor of the enzyme cytochrome P450 (CYP) 2C19. The inhibition of CYP2C19 by fluoxetine may lead to an increase in the plasma concentration of other drugs that are metabolized by this enzyme, such as glipizide and hydroxycyclohexyl. Fluoxetine inhibits human uric acid secretion and increases plasma concentrations of uric acid. This drug also inhibits human erythrocyte dihydropyrimidine dehydrogenase, leading to increased blood levels of pyrimidines, especially cytotoxic ones like 6-fluoro-3-indoxyl-beta-D-galactopyranoside. Fluoxetine has been shown to have a protective effect against acetaminophen toxicity in rats because it enhances the conversion of acetaminophen to its less toxic metabolite N-acetylcysteine.