Compostos Halogenados

<p>Applications Ethyl 8-chloro-6-hydroxyoctanoate is used in biological study for the enzymic resolution of chiral chlorohydrin precursor for (R)-α-lipoic acid synthesis via lipase catalyzed enantioselective transacylation with vinyl acetate.<br>References Zhou, W. et al.: Journal of Molecular Catalysis B: Enzymatic (2014), 99, 102-107<br></p>

<p>Applications tert-Butyl-(3-iodo-1,1-dimethyl-propoxy)-dimethyl-silane (cas# 105262-85-9) is used as a reagent in the preparation of Methyl Acetoacetate.<br>References Heslin, J. C., et al.: J. Chem. Soc. [Perkin 1]. 6, 1417 (1988)<br></p>

<p>Applications p-Chloroaniline-d4 Deuterium Chloride is an intermediate in synthesizing N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide-d4 (C377537), an isotope labelled analog of N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide. N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide is an impurity of Chlorhexidine Digluconate (C292770). Chlorhexidine gluconate is an antimicrobial irrigant that is used as an antiseptic for the skin in the healthcare industry. It is used in hospitals to prevent infection of patients during surgeries and can also be found in mouth rinses.<br>References Addy, M. &amp; Wright, R.: J. Clin. Periodont., 5, 198 (1978); Kuruvilla, J. &amp; Kamath, M.: J. Endododont., 24, 472 (1998); Maki, D., et al.: Lancet, 338, 339 (1991); Popovich, K., et al.: Inf. Cont. Hosp. Epidem., 30, 959 (2009); Rosenberg, A., et al.: Surg. Gyn. Obst., 143, 789 (1976)<br></p>

<p>Applications 9-Bromononanenitrile is used as a reactant for synthesis and its biological evaluation as potential antitrypanosomal agents.<br>References Artigas, A., et al.: Lett. Org. Chem. 15, 455 (2018)<br></p>

<p>Applications 1-Bromo-2-methoxy-d3-ethane is a useful isotopically labeled compound of 2-Bromoethyl Methyl Ether (B685140)<br></p>

<p>Applications 2-(3,5-Dichloro-2-hydroxyphenyl)-benzo[h]quinoline-4-carboxylic Acid is a useful research chemical.<br></p>

<p>Applications 16-Bromohexadecanenitrile is a useful research chemical.<br></p>

<p>Applications N,N-Bis(2-chloroethyl)aniline (cas# 553-27-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Sodium 2-Iodobenzenesulfonate is useful for the study of IBS-catalyzed oxidative rearrangement of tertiary allylic alcohols.<br>References Uyanik, M., et al.: Org. Lett., 11, 3470-3473 (2009)<br></p>

<p>Applications 2-Iodopropane-1,1,1,3,3,3-d6 (CAS# 39091-64-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)-1,4-dihydropyrimidine-5-carboxylate is a reagent in the synthesis of Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)pyrimidine-5-carboxylate (M303915) which is an intermediate of Rosuvastatin (R700500).<br>References Laufer, S., et al.: J. Med. Chem., 45, 2733 (2002), Palani, A., et al.: Bioorg. Med. Chem. Lett., 13, 709 (2003),<br></p>

<p>Applications Ethyl-6- bromo-4-[(pyrrolyl)-methyl]-5-hydroxy-1-methyl-2-[(phenylthio) methyl]-indole-3-carboxylate is a useful research chemical compound.<br></p>

<p>Applications Methyl 5-(4-Fluorophenyl)-(5S)-hydroxypentanoate is used in preparation of of Ezetimibe and intermediate thereof.<br>References Chen, J., et al.: Faming Zhuanli Shenqing, (2020);<br></p>

<p>Applications 1-Bromopentane-5,5,5-d3 (CAS# 75736-50-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3,5-Tribromo-2,4,6-Trimethylbenzene is a useful reagent for preparing highly durable superhydrophobic nanothorn arrays.<br>References Li, X., et al.: Small, 16, 1907013 (2020)<br></p>

<p>Applications (2S,3S,4S,5R)-6-(2-(Difluoromethoxy)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is metabolite of 2-(Difluoromethoxy)-acetaldehyde (D442365(M)). 2-(Difluoromethoxy)-acetaldehyde is a derivative of 2-(Difluoromethoxy)ethanol (D423695(M)), which is a useful reactant in the synthetic preparation of N-substituted alkoxyalkanamides as modulators of the integrated stress response pathway. The glucuronide that is attached to 2-(Difluoromethoxy)-acetaldehyde by the glycosidic bond.<br>References Atton, H., et al.: PCT Int. Appl. (2020), WO 2020216766 A1<br></p>

<p>Applications 3,4-Dichlorothiophene-2-carboxylic acid is a reagent used in the preparation of nicotinamides as PDE4 D isoenzymes inhibitors.<br>References Marfat, A. et al.: PCT Int. Appl., (1998)<br></p>

<p>Applications N-​(4-​Chlorophenyl)​-​3-​[(4-​chlorophenyl)​sulfinyl]​-​2-​hydroxy-​2-​methylpropanamide is a useful research chemical.<br></p>

<p>Applications 1,4-Dichloro-2-[(chloromethyl)thio]-benzene is an intermediate in the synthesis of Phenkapton(&gt;90%) (P294575). Phenkapton is an antiparasitic agent.<br>References Rico, A., et al.: Environ. Toxicol. Chem., 35, 494 (2016), Bai, G., et al.: Lihua Jianyan, Huaxue Fence, 49, 835 (2013)<br></p>

<p>Applications N-(4-Difluoromethoxy-2-nitrophenyl)acetamide is a key reagent used in the preparation of 2-mercapto-5-difluoromethoxy-1H-benzimidazole; an important medicinal intermediate.<br>References Vora, J. J., et al.: Adv. Appl. Sci. Res., 2, 89 (20110}, Xu, B., et al.: Jingxi Huagong, 17, 295 (2000)<br></p>

<p>Applications 4-Bromo-1-butanol is a useful reactant for the synthesis of tetrasubstituted alkenes from cross-​electrophile coupling and tandem metallacycle formation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimkin, K.W., et al.: J. Am. Chem. Soc., 140, 7074-78 (2018);<br></p>

<p>Applications 4'-Chloroacetophenone-d7 (CAS# 1174565-85-5) is a useful isotopically labeled research compound.<br></p>