Compostos Halogenados

Applications Ethyl 8-chloro-6-hydroxyoctanoate is used in biological study for the enzymic resolution of chiral chlorohydrin precursor for (R)-α-lipoic acid synthesis via lipase catalyzed enantioselective transacylation with vinyl acetate.
References Zhou, W. et al.: Journal of Molecular Catalysis B: Enzymatic (2014), 99, 102-107

Applications tert-Butyl-(3-iodo-1,1-dimethyl-propoxy)-dimethyl-silane (cas# 105262-85-9) is used as a reagent in the preparation of Methyl Acetoacetate.
References Heslin, J. C., et al.: J. Chem. Soc. [Perkin 1]. 6, 1417 (1988)

Applications p-Chloroaniline-d4 Deuterium Chloride is an intermediate in synthesizing N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide-d4 (C377537), an isotope labelled analog of N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide. N1-(4-chlorophenyl)-3,12-diimino-N14-2-chlorophenyl-2,4,11,13-Tetraazatetradecanediimidamide is an impurity of Chlorhexidine Digluconate (C292770). Chlorhexidine gluconate is an antimicrobial irrigant that is used as an antiseptic for the skin in the healthcare industry. It is used in hospitals to prevent infection of patients during surgeries and can also be found in mouth rinses.
References Addy, M. & Wright, R.: J. Clin. Periodont., 5, 198 (1978); Kuruvilla, J. & Kamath, M.: J. Endododont., 24, 472 (1998); Maki, D., et al.: Lancet, 338, 339 (1991); Popovich, K., et al.: Inf. Cont. Hosp. Epidem., 30, 959 (2009); Rosenberg, A., et al.: Surg. Gyn. Obst., 143, 789 (1976)

Applications 1,4-Dichlorocyclohexane is a solvent used in the synthesis of chemical foamed polysulfide sealants for aerospace fuel tank use.
References Stevens, B. E. et al.: U.S. Pat. Appl. Publ. 18 pp. (2017)

Applications 9-Bromononanenitrile is used as a reactant for synthesis and its biological evaluation as potential antitrypanosomal agents.
References Artigas, A., et al.: Lett. Org. Chem. 15, 455 (2018)