Nitro

<p>Applications Methyl 3-nitroisonicotinate (cas# 103698-10-8) is a useful research chemical.<br></p>

<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>

<p>Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);<br></p>

<p>Impurity Iohexol USP Related Compound C<br>Applications N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.<br>References Haavaldsen, J. et al.: Acta Pharmac. Sue., 20, 219 (1983);<br></p>

<p>Applications 4-Nitrocatechol can be used as a catalyst and an antibacterial against intestinal bacteria.<br>References Jones, Matthew D., et al.: Polymer Preprints (Amer. Chem. Soc.), 48(2), 873-874 (2007);Jeong, Eun-Young, et al.: Food Chem.,  115(3), 1006-1010 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications 4-Nitrobenzoic Acid is used in the synthesis of anti-Trypanosoma cruzi agents in the treatment of chagas disease.<br>References Palace-Berl, F. et al.: Bioorg, Med. Chem. Lett., 21, 5395 (2013); Zhou, L. et al.: J. Med. Chem., 56, 796 (2013);<br></p>

<p>Impurity Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole<br>Applications Niltazoxanide USP Related Compound A 2-Amino-5-nitrothiazole.<br>References Kariduraganavar, M. et al.; J. Mol. Struct. 987, 158 (2011). Tambe, S. J. et al.; Appl Polymer Sci. 114, 2291 (2009)<br></p>

<p>Applications N-Nitrosodipropylamine is a a N-nitrosamine derivative. The mutagenic activities of the carcinogenic N-nitrosamines were studied on both S. typhimurium TA100 and TA98, revealing moslty mutagenic activities on TA100 with few exceptions on TA98 (1). Water contaminant (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Yahagi, T. et al.: Mutat. Res. Fund. Mol. Mech. Mut. 1977. Apr:48(2) p121-1292. Mestankova, H. et al.: Water Res. 2016 Apr 15;93:110-20<br></p>

<p>Applications 4-ETHYL-3-NITROBENZOIC ACID (cas# 103440-95-5) is a useful research chemical.<br></p>

<p>Applications 4-Nitroguaiacol (cas# 3251-56-7) is a compound useful in organic synthesis. Dyes and metabolites.<br>References Conn, H., et al.: J. Bacteriol.,54, 291(1947), Schleifer, K., et al.: Bacteriol. Rev., 36, 407 (1972), Collins, M., et al.: J. Gen. Microbiol., 100, 221(1977), Schleifer, K., et al.: Methods Microbiol., 18, 123 (1985),<br></p>

<p>Applications N,N-dimethyl-2,4-dinitroaniline (cas# 1670-17-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2,5-Dinitrotoluene, is a building block used in various chemical synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3,4-Dinitroaniline is a useful intermediate for the preparation of various industrially important chemicals like dyes, pestices, herbicides and other useful research chemicals.<br>References Sivakumar, K. K., et al.: Int. J. Res. Pharm. Chem., 4, 517 (2014); Shahinian, E. G. H., et al.: Sci. Bull. B: Chem. Mater. Sci., 73, 153 (2011); Jahn, U.: Science of Synthesis, 41, 371 (2010)<br></p>

<p>Applications Methyl 2-Nitro-4-(trifluoromethyl)benzoate has been used in the synthesis of isoxazolinone antibacterial agents, using nitrogen as a replacement for the stereogenic center of the molecule. Also used in the preparation of benzo[b]azepines as inhibitors of cholesterol ester transfer.n<br>References Snyder, L. et al.: Bioorg. Med. Chem. Lett., 14, 4735 (2004);<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Applications N,N-Dimethyl-4-nitrobenzamide<br></p>

<p>Applications N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.<br>References Hiasa, Y., et al.: Cancer Lett, 145, 143-149 (1999)<br></p>

<p>Applications 3-Nitrobenzoylacetonitrile (cas# 21667-64-1) is a useful research chemical.<br></p>