Nitro

<p>Stability Hygroscopic<br>Applications N-(3-Hydroxypropyl) 4-hydroxy-2-nitroaniline is a hair ingredient. It is used as a semipermanent (nonoxidative) hair colorant and as a toner in permanent (oxidative) hair dye products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Burnett, C. L., et al.: Int. J. Toxicol., 28, 217S (2009); Yazar, K., et al.: Contact Dermatitis, 61, 269 (2009)<br></p>

<p>Applications rac-4-Benzyloxy-3-nitrostyrene Oxide (cas# 51582-41-3) is a compound useful in organic synthesis.<br>References Karellas, P., et al.: J. Med. Chem., 51, 6128 (2008),<br></p>

<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>

<p>Applications 4-Nitrocatechol can be used as a catalyst and an antibacterial against intestinal bacteria.<br>References Jones, Matthew D., et al.: Polymer Preprints (Amer. Chem. Soc.), 48(2), 873-874 (2007);Jeong, Eun-Young, et al.: Food Chem.,  115(3), 1006-1010 (2009)<br></p>

<p>Applications 3,5-DINITRO-4-HYDROXYBENZOIC ACID (cas# 1019-52-9) is a useful research chemical.<br></p>

<p>Applications N-(Nitrosomethyl)ethanolamine can be used to study the chemical-molecular perspective of the liver specificity of the carcinogenicity of NOCs.<br>References Yuan, J., et.al.: Chem. Res. Toxicol., 25, 2432-2442, (2012);<br></p>

<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>

<p>Applications N,N-dimethyl-2,4-dinitroaniline (cas# 1670-17-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Nitroguaiacol (cas# 3251-56-7) is a compound useful in organic synthesis. Dyes and metabolites.<br>References Conn, H., et al.: J. Bacteriol.,54, 291(1947), Schleifer, K., et al.: Bacteriol. Rev., 36, 407 (1972), Collins, M., et al.: J. Gen. Microbiol., 100, 221(1977), Schleifer, K., et al.: Methods Microbiol., 18, 123 (1985),<br></p>

<p>Applications N,N-Diethyl-4-nitroaniline<br></p>

<p>Applications N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.<br>References Hiasa, Y., et al.: Cancer Lett, 145, 143-149 (1999)<br></p>

<p>Applications 2-nitrobenzene-1,4-diamine (cas# 5307-14-2) is a useful research chemical.<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>

<p>Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)<br></p>

<p>Applications 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino)quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors.<br>References Dudash, J., et al.: Bioorg. Med. Chem. Lett., 21, 4790 (2005); Hellerstein, M., et al.: J. Clin. Invest. 100, 1305 (1994)<br></p>

<p>Applications Methyl 2-Nitro-4-(trifluoromethyl)benzoate has been used in the synthesis of isoxazolinone antibacterial agents, using nitrogen as a replacement for the stereogenic center of the molecule. Also used in the preparation of benzo[b]azepines as inhibitors of cholesterol ester transfer.n<br>References Snyder, L. et al.: Bioorg. Med. Chem. Lett., 14, 4735 (2004);<br></p>

<p>Applications N,N-Dimethyl-4-nitrobenzamide<br></p>

<p>Applications N,N-Diamylnitrosamine (cas# 13256-06-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,3-Dinitrobenzene is used as an analyte to detect explosive environments (1), including those containing picric acid (2). Neurotoxic agent (3). Drinking water contaminant candidate (CCL3) as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. ÄŒapka, L. et al.: J. Chromatogr. A. 2015 Apr 3;1388:167-73.2. Sanda, S. et al.: Chem. Commun. (Camb) 2015 Apr 18;51(30):6576-93. Maurer, L. et al.: Neurotoxicology. 2016 Mar;53:74-84<br></p>

<p>Applications Nitrofurate is a useful organic reagent. It is used for preparation of polycyclic small molecules.<br>References Tan, D., et al.: J. Am. Chem. Soc., 121, 9073 (1999); Lu, P., et al.: Org. Lett., 11, 5710 (2009);<br></p>

<p>Applications Ethyl Nitroacetate is an ester of nitrocarboxylic acid used as an intermediate in the preparation of unsubstituted amino acids.<br>References Sidorin, G.I.: Gig. Aspe. Okhr. Zdor. Nasel., 144 (1977);<br></p>

<p>Applications Methyl 3-nitroisonicotinate (cas# 103698-10-8) is a useful research chemical.<br></p>

<p>Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);<br></p>

<p>Applications 3,4-Dinitroaniline is a useful intermediate for the preparation of various industrially important chemicals like dyes, pestices, herbicides and other useful research chemicals.<br>References Sivakumar, K. K., et al.: Int. J. Res. Pharm. Chem., 4, 517 (2014); Shahinian, E. G. H., et al.: Sci. Bull. B: Chem. Mater. Sci., 73, 153 (2011); Jahn, U.: Science of Synthesis, 41, 371 (2010)<br></p>

<p>Applications 1,5-Dinitroanthraquinone 97% (cas# 82-35-9) is a useful research chemical.<br></p>

<p>Impurity Iohexol USP Related Compound C<br>Applications N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.<br>References Haavaldsen, J. et al.: Acta Pharmac. Sue., 20, 219 (1983);<br></p>

<p>Applications N-Nitrosodipropylamine is a a N-nitrosamine derivative. The mutagenic activities of the carcinogenic N-nitrosamines were studied on both S. typhimurium TA100 and TA98, revealing moslty mutagenic activities on TA100 with few exceptions on TA98 (1). Water contaminant (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Yahagi, T. et al.: Mutat. Res. Fund. Mol. Mech. Mut. 1977. Apr:48(2) p121-1292. Mestankova, H. et al.: Water Res. 2016 Apr 15;93:110-20<br></p>

<p>Applications 4-hydroxy-2-nitrobenzoic acid (cas# 74230-08-3) is a useful research chemical.<br></p>