Cetonas

<p>Applications 1-[3,4-Bis(phenylmethoxy)phenyl]ethanone is an intermediate in synthesizing Arbutamine (A766300). It is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.<br>References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);<br></p>

<p>Applications 2-Hexylidenecyclopentanone is a compound that is found in fragrance.<br>References Scognamiglio, J., et al.: Food Chem. Tox., 3, S577 (2012)<br></p>

<p>Applications 4-Cyanocyclohexanone is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist.<br>References Marfat, A., et al.: PCT Int. Appl. (1998), WO 9845268 A1 19981015; Schmidt, D., et al.: Bioorg. Med. Chem. lett., 20, 3426 (2010)<br></p>

<p>Applications Cyclododecanone is a general chemical reagent used in organic synthesis.<br>References Hu, Y. et al.: Org. Biomol. Chem., 14, 3022 (2016);<br></p>

<p>Impurity: Propafenone EP Impurity H<br>Applications: Flavanone (Propafenone EP Impurity H) is a Propafenone (P757500) impurity.<br>References Kitagawa, S., et al.: Biol. Pharm. Bull., 29, 1 (2006), Boccard, J., et al.: Eur. J. Pharm. Sci., 36, 254 (2009),<br></p>

<p>Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.<br>References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)<br></p>

<p>Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Acetoxymethyl Vinyl Ketone (cas# 38982-28-4) is a compound useful in organic synthesis.<br>References Zingel, V., et al.: Eur. J. Med. Chem., 25, 673 (1990), Sabourin, P., et al.: Carcinogenesis, 13, 1633 (1992),<br></p>

<p>Applications 10-Hydroxy-2-decanone is an intermediate used in the synthesis of Monooxoisodecyl Phthalate (M547915), which is a derivative of Monoisodecyl Phthalate (M547905) which activates mouse and human Peroxisome Proliferator-Activated Receptors (PPARs).<br>References Bisset, K. M., et al.: Neurochem. Internatio., 59 (5), 706 (2011); Bility, M. T., et al.: Toxico. Sci., 82 (1), 170 (2004)<br></p>

<p>Applications 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE (cas# 2892-51-5) is a useful research chemical.<br></p>

<p>Applications 1-(2,4-Bis(benzyloxy)phenyl)ethanone is a useful research chemical for organic synthesis and other chemical processes.<br>References Chen, D., et al.: Eur. J. Med. Chem., 87, 765 (2014); Malik, N., et al.: Tetrahedron Lett., 54, 4121 (2013)<br></p>

<p>Applications 2-Heptacosanone is a useful research chemical for organic synthesis and other chemical processes.<br>References Dastillung, M., et al.: J. Chem. Res. Synopses, 5, 166 (1980), Liu, Q., et al.: Advan. Mater. Res., 230, 842 (2011)<br></p>

<p>Applications Benzyl p-Toluylketone (cas# 2001-28-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Z., et al.: Bioorg. Med. Chem. Lett., 18, 2211 (2008), Gadad, A., et al.: Bioorg. Med. Chem., 16, 276 (2008),<br></p>

<p>Applications 1-(2-Hydroxy-4,6-dimethylphenyl)-ethanone was investigated for its properties as an antibacterial agent and urease inhibitory effects.<br>References Ngan, L.T., et al.: J. Agri. Chem., 60, 9062 (2012); Chermenskaya, T.D., et al.: Industrial. Crops. Prod., 36, 122 (2012);<br></p>

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>

<p>Stability Volatile<br>Applications Cyclobutanone is a member of cycloketone compounds that have potential genotoxic and cytotoxic effects and are most commonly found in irradiated food.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anandon, A., et al.: EFSA Journal, 9, 1930 (2011); Delincee, H., et al.: Radiat. Phys. Chem., 63, 431 (2002); Obana, H. ,et al.: J. Health Sci., 52, 375 (2006)<br></p>

<p>Applications 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).<br>References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012)<br></p>

<p>Applications 4,4-Dimethoxy-2-butanone is a reactant in the synthesis of naphthalimide-naphthyridine derivatives as a fluorescent probe for the detection of hydroxyl radicals in living cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, L., et. al.: Chem. Commun., 50, 4843 (2014)<br></p>

<p>Applications 5-[(4-Fluorobenzylidene]-2,4-thiazolidinedione (cas# 262601-87-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Cyclohexylethanone is used in the synthesis of thiosemicarbazide derivatives which exhibits biological activity.<br>References Venkatesh, K., et al.: J. Chem. Pharm. Res., 7, 437-445 (2015)<br></p>

<p>Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxy-cyclohexanone is a chemical reagent used in organic synthesis. Used in enantioselective conjugate-addition reactions as well as the cross coupling of enantioenriched secondary potassium β-trifluoroboratoamides.<br>References Molander, G. et al.: Adv. Synth. Catal., 355, 3037 (2013); Kitanosono, T. et al.: Chem. Asian J., 9, 179 (2014);<br></p>

<p>Applications (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.<br>References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981); Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987)<br></p>

<p>Applications 1-Cyclopropyl-1,3-butanedione is a reagent in regioselective synthesis of pyrazolylpyrazolopyrimidine derivatives in aqueous medium for antimicrobial agents.<br>References Novinson, T., et al.: J. Med. Chem., 17, 645 (1974); Aggarwal, R., et al.: Eur. J. Med. Chem., 46, 3038 (2011)<br></p>

<p>Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.<br></p>

<p>Applications 1-(2-AMINO-5-HYDROXYPHENYL)ETHANONE (cas# 30954-71-3) is a useful research chemical.<br></p>

<p>Applications 5β-Estrane-3,17-dione is an intermediate in the synthesis of neuroactive steroids useful in the treatment of CNS-related diseases.<br>References PCT Int. Appl. (2015), WO 2015180679 A1 20151203;<br></p>

<p>Applications 2-ETHYL-1-INDANONE (cas# 22351-56-0) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(2-oxopropyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione (cas# 57384-79-9) is a useful research chemical.<br></p>

<p>Applications 3-Isochromanone can be used to prepare an organic catalyst.<br>References Wu, G., et.al.: Faming Zhuanli Shenqing, 31, (2021);<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Applications (E)-2-Heptylidenecyclopentanone, is a common substance that is found in fragrances.<br></p>

<p>Stability Unstable in Aqueous Solution<br>Applications (±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone is a volatile organic compound used in the silylation of alcohols,<br>References D'Sa, B.A. et al.: J. Org. Chem., 62, 5057 (1997);<br></p>