Amidas

<p>Clopamide is a diuretic drug that belongs to the group of protein genes. It is used in the treatment of chronic heart failure, low-density lipoprotein cholesterol and infectious diseases. Clopamide has been shown to increase the glomerular filtration rate by inhibiting the sodium citrate enzyme, which is involved in the formation of urine from blood plasma. This drug also reduces blood pressure by blocking angiotensin II receptors on vascular smooth muscle cells. Clopamide does not have any significant interactions with other drugs, although caution should be exercised when using it with cardiac drugs due to its effects on blood pressure.</p>

<p>Parathyroid hormone-related protein (PTHrP) is a peptide hormone produced by the parathyroid gland that functions as a phosphatase, inhibiting alkaline phosphatase. It also has an inhibitory effect on osteoclastic bone resorption and stimulates osteoblastic bone formation. PTHrP has been shown to be useful in treating osteoporosis and Paget's disease. It also has been used in conjunction with dexamethasone to treat patients with malignancies of the head and neck. PTHrP is an inhibitor of protein kinase A and phosphodiesterases, which are enzymes that regulate cellular processes such as proliferation and differentiation.</p>

<p>2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide is a carboxamide analog of dibucaine. It is synthesized from chloroacetyl chloride and isatin in the presence of sodium hydroxide. The synthesis has been scaled to an industrial level. 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide has been shown to have analgesic properties, similar to those of dibucaine. Radiolysis of this compound gives a carboxylic acid and a heterocyclic ring product.</p>

N,N-Dimethylformamide dibenzyl acetal is an organic solvent that has a low volatility and high solubility in water. It is used as a cosolvent for reactions involving carboxylic acids, formamides, and epoxides. N,N-Dimethylformamide dibenzyl acetal can be used to produce peroxide as a reagent for oxidation reactions. Hydrogen peroxide can be produced from this compound by treatment with thionyl chloride or alkanoic acid. This chemical is also derivatized by the mesoporous method to provide mesoporous silica nanoparticles with enhanced surface area.

H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl is a monoclinic crystalline compound. It has a molecular weight of 607.14 and contains the dipeptide Tyr-Lys in its structure. H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl crystallizes in the P21/c space group and has an asymmetric unit cell with dimensions a=8.851 Å, b=7.965 Å and c=5.98 Å. This compound has been shown to have antibacterial properties against methicillin resistant Staphylococcus aureus (MRSA) isolates and Clostridium perfringens strains by inhibiting bacterial protein synthesis through inhibition of peptidyl transferase activity.

<p>N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide is a chiral biocatalytic agent, which is synthesized by chemoenzymatic or enzymatic reactions. It has been used in enantioselective synthesis of 4-aminoacetophenone and as an antiarrhythmic agent. This compound is not active against bacterial infections.</p>

ATP-sensitive K+ channel blocker

<p>Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.</p>

<p>Parathyroid hormone (PTH) is a peptide hormone that regulates calcium and phosphate balance in the body. PTH is secreted by the parathyroid glands, located near the thyroid gland in the neck. It is also known as parathormone or parathyrin. The active form of PTH, called pTH (1-34) amide, has been shown to stimulate bone resorption and to inhibit bone formation. The amino acid sequence of this hormone starts with arginine and ends with phenylalanine. The N-terminal amino acid residue is an aspartic acid or asparagine and histidine is the only basic residue in this molecule. This molecule has two acidic residues, glutamic acid and aspartic acid, which are found on the side chains of two amino acids: aspartic acid and glutamic acid. Valine is found at position 3 and phenylalanine at position 34.</p>

<p>Please enquire for more information about 3-Nitro-4-[[(tetrahydropyran-4-yl)methyl]amino]benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-5-chloro-N,3-dimethylbenzamide is a synthetic compound. It has been shown to induce necrotic cell death in mammalian cells. This compound was synthesized by the reaction of 2-aminoquinoline with a Grignard reagent, followed by nitration of the resultant amine. The synthesis of this compound was thermodynamically favorable and exhibited good solubility in water. The chlorantraniliprole and anthranilic acid moieties are activated with an acylation reaction, which allows them to bind to the ryanodine receptor and inhibit calcium release from the sarcoplasmic reticulum (SR) with ammonolysis. This inhibition leads to ferroptosis, a type of programmed necrosis.</p>

<p>L-Glutamic acid alpha-amide is an ester hydrochloride that is a tissue culture amide. It is a cyclic peptide analog and a hydroxyl group. L-glutamic acid alpha-amide has been shown to inhibit the inflammatory response in the bowel disease, Crohn's disease, by blocking the toll-like receptor 4 and 5. This drug also inhibits protein synthesis, which may be due to its ability to bind to fatty acids, thereby inhibiting the production of proteins vital for cell division.</p>

<p>N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide is a fine chemical that can be used as a reagent or intermediate. It is a versatile building block that can be used in the production of useful scaffolds or useful intermediates. This compound has been shown to react with many different types of chemicals, including alcohols and amines. N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide can also be used as a reaction component in the synthesis of diverse compounds.</p>

<p>Please enquire for more information about Mca-Amyloid beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Phenylacetyl-(D-Arg2·28,p-chloro-Phe6, Homoarg 9·29,Tyr(Me)10, Abu 15, Nle 27)-GRF (1-29) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>2,2-Dimethylpropionamide is a synthetic chemical that has been shown to have cytotoxic and biochemical properties. It has been tested on leukemia cells (K562) and has been shown to inhibit the bcr-abl kinase. 2,2-Dimethylpropionamide has also been shown to inhibit the production of amide radicals in human serum under constant pressure. The structure of this compound was solved using X-ray diffraction data.</p>

<p>Please enquire for more information about GLP-1 (7-36)-Lys(6-FAM) amide (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

(S)-2-Aminobutyramide hydrochloride is a chiral amide compound, which is utilized primarily in scientific research settings. This compound is typically synthesized through the resolution of racemic mixtures or other specialized chemical processes that ensure the purity and stereospecificity required for research purposes.The mode of action of (S)-2-Aminobutyramide hydrochloride revolves around its role as an intermediate in chemical synthesis, serving as a building block for the production of more complex molecules. It has a noteworthy chiral configuration, which makes it an essential component in the formation of enantiomerically pure substances. This aspect is crucial in fields like pharmaceuticals, where stereochemistry can significantly impact biological activity.Its applications extend to various domains such as the synthesis of therapeutic agents, biochemical research, and the development of novel materials. Researchers value it for its ability to contribute to the fine-tuning of molecular assemblies, making it indispensable in studies focused on the interaction and function of chiral molecules. The hydrochloride form aids in its stability and solubility, which are important attributes for laboratory manipulation and experimentation.

<p>Please enquire for more information about Dnp-Pro-TNF-alpha (71-82) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>