Anéis de 6 membros

<p>Applications 3,4,5-Trimethoxytoluene is a reagent for oxadiazolylindazole sodium channel modulators which are neuroprotective toward hippocampal neurons.<br>References Clutterbuck, L. A., et al.: J. Med. Chem., 52, 2694 (2009);<br></p>

<p>Applications (4-(tert-Butyl)-1,2-phenylene)dimethanol is an intermediate in the synthesis of 4-tert-Butyl-1,2-bis(chloromethyl)benzene (B807070). 4-tert-Butyl-1,2-bis(chloromethyl)benzene is used as a reactant in the preparation of dihydronaphthalenes/naphthalenes via cobalt-catalyzed formal [4+2] cycloaddition of α,α'-dichloro-ortho-xylenes with alkynes.<br>References Komeyama, K., et al.: Angew. Chem. Int. Ed., 53, 11325 (2014)<br></p>

<p>Applications 2,3,5-Trimethylbenzonitrile is an methyl-substituted benzonitrile is an intermediate in the synthesis of Ketoprofen (K200800) related compounds.<br></p>

<p>Applications 1-(Benzyloxy)propan-2-one (cas# 22539-93-1) is a useful research chemical.<br></p>

<p>Applications Pentadecyltriphenylphosphonium Bromide is an intermediate used in the synthesis of (Z)-12-Heptacosene (H635230), which is an unsaturated lipid and a component of sex pheromones of queen bees (Bobus terrestris) and species of orchids.<br>References Xu, S.; et al.: Evolution, 65, 2606 (2011); Krieger, G. M.; et al.: L J. Chem. Ecol., 32, 453 (2006).<br></p>

<p>Stability Store in a Cool Dry Area.<br>Applications A metabolite of 1,4-diethenylbenzene.<br>References Linhart, I., et al.: Xenobiotica, 19, 645 (1989),<br></p>

<p>Applications Wittig reagent.<br></p>

<p>Applications (1S,3S,4S)-(-)-3,5-dinitrobenzoate Menthol is an intermediate in the synthesis of (±)-Neoisomenthol (N389960) which is a useful synthetic intermediate. It is used to prepare alkyl and aryl esters by chemoselective acylation of alkyl and aryl alcohols with carboxylic acid anhydrides in the presence of magnesium bis(trifluoromethylsulfonyl)amide under solvent-free conditions.<br>References Chakraborti, A., et al.: J. Org. Chem., 71, 5785 (2006)<br></p>

<p>Applications rac-trans-[3-Hydroxycyclohexyl]benzamide (cas# 177366-90-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Phenylselenyl Bromide is used as a reagent in the synthesis of the antihyperglycemic agent, (+)-Antroquinonol. Phenylselenyl Bromide is also used in the preparation of 9-epi-Artemisinin (A777505); the chiral isomer of Artemisinin (A777500) which is an antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sulake, R.S., et al.: J. Org. Chem., 80, 6044 (2015); Orabi, K.Y. et al.: Phytochem., 51, 257 (1999); Jefford, C.W. et al.: Helv. Chim. Acta, 83, 1239 (2000); Klayman, D.L., et al.: Science, 228, 1049 (1985)<br></p>

<p>Applications Methyl 2-(3-Nitrobenzylidene)-3-oxobutanoate is a useful reactant in organic synthesis.<br>References Miao, Chun-Bao, et al.: Heterocycles, 87(4), 853-859 (2013);Kang, Soosung, et al.: Bioorg. &amp; Med. Chem., 21(14), 4365-4373 (2013);Li, Wan, et al.: Archiv der Pharmazie (Weinheim, Germany), 346(9), 635-644 (2013)<br></p>

<p>Applications Dibenzyl Hydrogen Phosphate (cas# 538-60-3) is a compound useful in organic synthesis.<br></p>

<p>Applications TRIPHENYLSILANE (cas# 789-25-3) is a useful research chemical.<br></p>

<p>Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boettecher, B. &amp; Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)<br></p>

<p>Applications Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(Benzyloxy)-3-[[bis(benzyloxy)phosphoryl]oxy]propan-2-ol is an intermediate in the synthesis of Dihydroxyacetone Phosphate Lithium Salt (D450538), which is a metabolic intermediate involved in involved in a wide variety of metabolic pathways including glycolysis and lipid biosynthesis. In plants, Dihydroxyacetone phosphate is involved with the synthesis of vitamin B6.<br>References Jun Ogawa et. al.: et al.: Bioscience, biotechnology, and biochemistry, 67(4), undefined (2003-6-6); John P Richard, Biochemistry, 51(13), undefined (2012-3-14);<br></p>

<p>Applications 4,5-Dimethyl-o-phenylenediamine is used in biological processes as a substrate for CobT nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella typhimurium LT2.<br>References Trzebiatowski, J.R., et al.: J. Biol. Chem., 272, 17662 (1997); Johnson, M.G., et al., J. Biol. Chem., 267, 13302 (1992); Cheong, C., et al.: J. Biol. Chem., 277, 41120 (2002)<br></p>

<p>Applications METHYL 2-(4-OXOCYCLOHEXYL)ACETATE (cas# 66405-41-2) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications 4,4'-(1,4-Phenylenebis(ethene-2,1-diyl))dibenzonitrile (cas# 13001-40-6) is a useful research chemical.<br></p>

<p>Applications 1,4-Bis(diphenylphosphino)butane is a catalyst precursor used in organic synthesis such as the preparation of phenanthrothiazoles.<br>References Shi, X. et al.: J. Org. Chem., 82, 3886 (2017);<br></p>

<p>Applications 2-Phenylpropionitrile (cas# 1823-91-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(4-Octylphenyl)ethanol (cas# 162358-05-6) is a compound useful in organic synthesis.<br></p>

<p>Applications α-Chlorophenylacetyl Chloride is a reagent used for dehydrohalogenation of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brady, W.T., et al.: J. Org. Chem., 45, 3525 (1980); Brady, W.T., et al.: J. Org. Chem., 45, 2025 (1980);<br></p>

<p>Applications 3-Formyl-4-nitrobenzonitrile is the tri-substitiuted derivative of benzene. 3-Formyl-4-nitrobenzonitrile is an intermediate used in the synthetic preparation of various pharmaceuticals exhibiting large spectrum of activity.<br>References Kunzer, A.R.. et al. Tetrahedron. Letters., 52, 1815 (2011);<br></p>

<p>Applications tert-Butyl (Triphenylphosphoranylidene)carbamate is used in the preparation of ketimines.<br>References Yan, W., et. al.: Organic Lett., 14, 2512 (2012)<br></p>

<p>Applications N,N’-Di-Boc (R)-1-Azido-3-[[3-fluoro-4-(morpholin-4-yl)phenyl]amino]propan-2-yl Acetate is an intermediate used in the synthesis of N-Desacetyl-N,O-descarbonyl O-Acetyl Linezolid (D288280), which is an impurity of Linezolid (L466500); an oxazolidinone antimicrobial that inhibits bacterial mRNA translation.<br>References Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996); Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996); Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998); Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002)<br></p>

<p>Applications Tetrahydropyran is a useful synthetic intermediate. Tetrahydropyranyl (THP-) ethers derived from the reaction of alcohols and dihydropyran are common intermediates in organic synthesis. In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Earl, R., et al.: Org. Synth., 7, 334 (1990); Kluge, A.: Org. Synth., 7, 160 (1990)<br></p>

<p>Applications 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications 4-Phenylmorpholine, is a biochemical reagent used in various chemical synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-(3,4-Dimethoxyphenyl)-1-(2-hydroxyphenyl)propan-1-one is an intermediate for the synthesis of dTAG-7 (D710015), which is a degradation tag, was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research.<br>References Hai-Tsang Huang., eLife, 1-29, (2017)<br></p>

<p>Applications 2-(4-Acetoxyphenyl)ethanol is an intermediate in synthesizing Oleocanthal (O524540). It is a compound of olive oil with potential use as anti-inflammatory and chemotherapeutic agents.<br>References Scotece, M., et. al.: Drug Discovery Today, 20, 406 (2015)<br></p>

<p>Applications N-ethyl-3-phenyl-1-propanamine hydrochloride (cas# 13125-63-8) is a useful research chemical.<br></p>

<p>Applications (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Dibenzyl Carbamate Phosphate is an intermediate used in the synthesis of Glycerol 3-Phosphoethanolamine (G601595), which is the product of a alcoholysis reaction with phosphatidylcholine and phosphatidylethanolamine.<br>References Meng, Z., et al.: Zhongguo Youzhi, 38, 32 (2013)<br></p>

<p>Applications 5-Bromo-1-(2-fluorophenyl)-2-pentanone is an intermediate in the synthesis of Prasugrel (P701150). Prasugrel is a novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome.<br>References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),<br></p>

<p>Stability Hygroscopic<br>Applications 3-Phenylpropylamine is an compound used for the synthesis of various pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamochi, Y., et al.: Tetrahedron. Lett., 32, 3511 (1991);<br></p>

<p>Applications 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>

<p>Applications Methyl 3-(4-Hydroxy-benzyl)-3-oxopropanoate (cas# 1391053-46-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Methyl-2-nitrobenzene is a toxic pollutant of the environment because of its large scale use in the production of explosives. It is a useful synthetic intermediate. It shows carcinogenic activity in rats.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sikandar, M., et al.: Chemosphere, 90, 1920 (2013); Jones, C., et al.: Carcinogen., 24, 779 (2003)<br></p>

<p>Applications 2-Aminobenzyl alcohol (cas# 5344-90-1) is a useful research chemical.<br></p>

<p>Applications 4-Acetamidophenyl Glycidyl Ether is an intermediate in the preparation of cardioselective β-adrenergic receptor antagonists.<br>References Jones, G. et al.: J. Pharm. Sci., 81, 397, (1992); Agrawal, A. et al.: J. Pharm. Sci., 66, 887, (1977)<br></p>

<p>Applications Methyl 3-(4-chlorophenyl)-3-oxopropanoate (cas# 22027-53-8) is a useful research chemical.<br></p>

<p>Applications Ethyl 4-Iodobenzoate (cas# 51934-41-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Intermediate in the preparation of alkoxycarbonylthiazolethione derivatives.<br></p>

<p>Applications 4-Benzoylbenzoic acid is a reagent that is used in the synthesis of BzATP Triethylammonium Salt, which is a selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.<br>References Cole, D., Yount, R.: J. Biol. Chem., 265, 22537 (1990); Atarashi, K., et al.: Nature, 455, 808 (2008)<br></p>

<p>Applications 3-Benzyloxy-2-(2-hydroxy-2-phenylethyl)-4H-pyran-4-one is an intermediate in the synthesis of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.<br></p>

<p>Applications An intermediate used in the production of various ectoparasiticides, drug metabolites and analgesic agents.<br>References Rastogi, S., et al.: J. Med. Chem., 16, 797 (1973), Maguire, J., et al.: Drug Metab. Disposition, 9, 393 (1981),<br></p>

<p>Applications N-(2-Chloroethyl)benzenesulfonamide is an intermediate for the synthesis of Bensulide (B166000), which is an organophosphate acetylcholinesterase inhibitor used as an herbicide (1) in the protection of crops through pesticides (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br></p>

<p>Applications 3,3,5,5-Tetramethylcyclohexanone (cas# 14376-79-5) is a useful research chemical and a pharmaceutical intermediate.<br>References Ebrahimi, H. P., et al.: Spectrochim. Acta A: Mol. Biomol. Spectrosc., 137, 1067 (2015); Bishop, A. C., et al.: Bioorg. Med. Chem. Lett., 16, 4002 (2006)<br></p>

<p>Applications Hexyltriphenylphosphonium Bromide is useful for the synthesis of phenolic components of Grains of Paradise (Aframomum melegueta).<br>References Hattori, H., et al.: Tetrahedron Letters, 60, 1989 (2019)<br></p>

<p>Applications Methyl 5-(2,2-Dibromoacetyl)-2-hydroxybenzoate is a by-product in the synthesis of Labetalol-1-carboxylic Acid (L096510), an impurity of the α-and β-adrenergic, Labetalol (L096500).<br></p>

<p>Applications 4-Benzyloxy-2-(2’-carbomethoxy)thiophenylnitrobenzene (cas# 329217-03-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(2,6-Dimethyl-3-hydroxyphenyl)-3-oxo-2-azaindolizidine (cas# 1796881-08-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(3-Acetoxypropyl)phenyl Acetate is an intermediate used in biological studies for biodistribution and elimination of xenoestrogen nonylphenol in Wistar rats.<br>References Oriyama, T., et al.: Synlett., 6, 701 (1997);<br></p>

<p>Applications N-Depropyl N-Benzyl Propafenone is used in the preparation of Propafenone analogues as antimalarial agents.<br>References Lowes, D. et al.: J. Med. Chem., 54, 7477 (2011); Ecker, G. et al.: J. Med. Chem., 39, 4767 (1996)<br></p>

<p>Applications 9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium is an intermediate in the synthesis of SkQR1 (S555050), a mitochondria-targeted plastoquinone antioxidant that exhibits neuroprotective effect. Potent Mitochondrial Targeted antioxidant protecting against the anti-cancer treatment related to oxidative stress (1). Depicted positive effects on rat memory. (2)SkQRl is the substrate of multidrug resistance pump P-glycoproten (Pgp 170) and selectively protects Pgp 170-negative cells against oxidative stress (3)<br>References Fetisova EK, et al. 2010. FEBS Lett. Feb 5;584(3):562-6Stelmashook EV, 2015. Biochemistry (Mosc). May;80(5):592-5 Fetisova EK, et al. 2015. Radiat Res. Jan;183(1):64-71<br></p>

<p>Applications 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters.<br>References Picard, F. et al.: J. Med. Chem., 45, 3406 (2002); Donkor, I. et al.: J. Med. Chem., 51, 4346 (2008);<br></p>

<p>Applications 4-Oxocyclohexanecarboxylic Acid is used in the preparation of Indomethacin (I641000) analogues used in the treatment of prostate cancer. In addition it is used in the synthesis of β-alanine derivatives as glucagon receptor antagonists.<br>References Liedtke, A. et al.: J. Med. Chem., 56, 2429 (2013); Lau, J. et al.: J. Med. Chem., 50, 113 (2007);<br></p>

<p>Applications Dibenzyl azodicarboxylate is a reagent used in the synthesis of Minocycline-d6 (M344797). Minocycline-d6 is a labeled second generation tetracycline antibiotic. Antibacterial.<br>References Zbinovsky, V., et al.: Anal. Profiles Drug Subs., 6, 323 (1977); Oringer, R.J., et al.: J. Periodontol., 73, 835 (2002)<br></p>

<p>Applications P,P'-[(1,2-Phenylene)bis(methylene)]bisphosphonic Acid P,P,P',P'-Tetraethyl Ester also used in claisen condensations. Also used in the synthesis of styrylbenzenes as β-amyloid binding ligands as well as free radical scavengers.<br>References Gavara, L. et al.: Tetrahedron Lett., 54, 817 (2013); Flaherty, D. et al.: J. Med. CHem., 53, 7992 (2010);<br></p>

<p>Applications 1,2-Dimethoxy-4,5-dinitrobenzene (cas# 3395-03-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 9-Hydroxydecanoic Acid Benzyl Ester is an intermediate in the synthesis of Monocarboxyisodecyl Phthalate (M525575), a metabolite of Dibutyl phthalate (DBP) (D429495), which is found widely in consumer products.<br>References Weber, A. E., et al.: J. Med. Chem., 35, 3755 (1992);<br></p>

<p>Applications N-Ethylbenzylamine is a reactant or reagent used in various organic syntheses. It is used in the preparation of CXCR4 injhibitors which are used to treat cancer metastasis and inflammation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bai, R. et al.: Eur. J. Med. Chem., 118, 340 (2016);<br></p>

<p>Stability Moisture Sensitive<br>Applications Phenyl Dichlorophosphate is used as a reagent in the synthesis of aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication. Also a reagent in the synthesis of nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as inhibitors of HCV NS5B polymerase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maiti, M., et al.: Org. Biomol. Chem., 13, 5158 (2015); Jonckers, T.H.M., et al.: J. Med. Chem., 57, 1836 (2014)<br></p>

<p>Applications Methyl 2-benzylhydrazinecarboxylate is an intermediate for the synthesis of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro.<br>References Kotzki, S. et al.: J. Pharm. Exp. Ther., 346, 424 (2013); Selwood, D&gt; et al.: J. Med. CHem., 44, 78 (2001)<br></p>

<p>Applications Phthalodinitrile monomers can be polymerized thermally in the presence of small amounts of curing agents into thermosetting polymers. Phthalodinitrile is a precursor to phthalocyanine which is used as a dye or pigment.<br>References Sastri, S. B. and Keller, T. M.: J. Polym. Sci. A Polym. Chem., 36, 1885-1890(1998), Löbbert, G. Phthalocyanines. In Ullmann's Encyclopedia of Industrial Chemistry, (Ed.)., (2000).<br></p>

<p>Applications Intermediate in the preparation of Benzoxazines.<br></p>

<p>Applications 2-Benzylaniline was used to study efficient and convenient heterogeneous palladium-catalyzed regioselective deuteration at the benzylic position.<br>References Kurita, T., et al.: Chem. Eur. J., 14, 664 (2008);<br></p>

<p>Applications Benzyl 6-Oxohexanoate is an intermediate in the synthesis of N-5-Carboxypentyl-1-deoxynojirimycin (C181200), which is a ligand used for the preparation of an affinity resin highly specific for glucosidase I purification. Glucosidase I is involved in the post-translational processing of N-linked glycoproteins.<br>References HettKamp, H., et al.: Eur. J. Biochem., 142, 85 (1984); Shailubhai, K., et al.: Biochem. J., 247, 555 (1987); Bause, E., et al.: FEBS, 278, 167 (1991)<br></p>

<p>Applications 2,4-Dinitrobenzenesulfonic Acid (cas# 89-02-1) is a useful research chemical.<br></p>

<p>Applications (αS)-α-Amino-4-nitrobenzenepropanamide (cas# 81677-61-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(Phenylmethoxy)-3-(2-propen-1-yloxy)-2-propanol (cas# 83016-75-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-(4-Aminophenyl)propionic acid (cas# 2393-17-1) is a useful research chemical.<br></p>

<p>Applications 4-Benzyloxy-2-(2’-carbomethoxy)thiophenylaniline (cas# 329217-05-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(Benzyloxy)-2-hydroxy-5-(sulfooxy)benzoic Acid is an intermediate used in the synthesis of 4-Hydroxy Flecainide (H942485), which is an analogue of Flecainide (F390000).<br>References Blom, Y., et al.: J. Chromatogr., 653, 138 (1993),<br></p>

<p>Applications Methyl 1,4-Benzodioxan-2-carboxylate is an intermediate used to prepare 2,3-dihydrobenzo[b|[1,4|dioxin- and indolealkylamine derivatives as potential antidepressants.<br>References Wang, S., et al.: Archiv der Pharmazie (Weinheim, Germany), 347, 32 (2014); Wang, S., et al.: Bioorg. Med. Chem. Lettt., 24, 1766 (2014)<br></p>

<p>Applications (cas# 1999-08-01) is a useful research chemical.<br></p>

<p>Applications 2-(Cyclopropylmethoxy)-acetic Acid 1,1-Dimethyl-2-[4-(methylsulfonyl)phenyl]-2-oxoethyl Ester is a useful research chemical for organic synthesis and other chemical processes.<br>References Leblanc, Y., et al.: Bioorg. Med. Chem. Lett., 9, 2207 (1999)<br></p>

<p>Applications 5-Chloro-4-nitro-2,1,3-benzoselenadiazole (cas# 20718-46-1) is a compound useful in organic synthesis.<br>References Turesky, R., et al.: J. Agric. Food Chem., 53, 3248 (2005),<br></p>

<p>Applications (2-Cyclobuten-1-yldimethylsilyl)benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.<br>References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);<br></p>

<p>Applications Benzyl 4-Fluorophenyl Ketone is used in the preparation and evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors.<br>References Singh, S. et al.: Bioorg. Med. Chem., 12, 1881 (2004);<br></p>

<p>Applications 2-(((10-(Benzyloxy)-10-oxodecan-2-yl)oxy)carbonyl)benzoic Acid is an intermediate in the synthesis of Monocarboxyisodecyl Phthalate (M525575), a metabolite of Dibutyl phthalate (DBP) (D429495), which is found widely in consumer products.<br></p>

<p>Stability -20°C Freezer<br>Applications Useful reagent for preparing amino acid pentachlorophenol active esters.<br>References Kovacs, J., et al.: J. Am. Chem. Soc., 89, 183 (1967)<br></p>

<p>Applications 4-Nitrobenzonitrile (cas# 619-72-7) is a useful research chemical.<br></p>

<p>Applications benzyl (2s)-4-oxoazetidine-2-carboxylate, is a building block used for various chemical synthesis such as for the synthesis of NMDA receptor antagonists, 3-alkyl-L-aspartic acids, and orally active β-lactam inhibitors.<br>References Baldwin, J.E. et al. Tetrahedron 51, 11581-11581, (1995); Hanessian, S. et al. Synlett , 33-33, (1992)<br></p>

<p>Applications N-tert-Butoxycarbonyl-3,4-dibenzyloxyphenylethylamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.<br>References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),<br></p>

<p>Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications 3-(3-(3-(Benzyloxy)propoxy)propoxy)propan-1-ol is an intermediate in the synthesis of 3,3'-[Oxybis(3,1-propanediyloxy)]bis[1-propanol] (O870290). 3,3'-[Oxybis(3,1-propanediyloxy)]bis[1-propanol] is derived from 3-(Benzyloxy)propyl 4-Toluenesulfonate (B288830), which is used as a reagent in the synthesis of Silodosin (S465000); an antidysuria drug. 3-(Benzyloxy)propyl 4-Toluenesulfonate is also used as a reagent in the preparation of aryloxyalkyl derivatives of adenine which have antiviral activity.<br>References Calogero, F., et al.: Eur. J. Org. Chem., 2015, 6011 (2015); Petrov, V.I., et al.: Chem. Heterocyc. Compd., 39, 1218 (2003)<br></p>

<p>Applications Benzyltriphenylphosphonium Chloride was used as a reagent in the organic synthesis of several compounds including that of stabilised phosphonium ylides containing saturated oxygen heterocycles. Also used in the synthesis of novel substituted cis-stilbene derivatives which display antimicrobial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aitken, R., et al.: Org. Biomol. Chem., 14, 1794 (2016); Jain, D., et al.: World J. Pharm. Sci., 4, 1473 (2015);<br></p>