Anéis de 6 membros

<p>Applications Used in the preparation of antifungal agents.<br>References Del Poeta, M. et al.; Antimicrob. Agents Ch., 42, 2495 (1998)<br></p>

<p>Applications 4-​Chloro-​3-​sulfobenzoic acid is a useful chemical for the preparation of pyridinylbiphenylcarboxamide derivatives for the use as nervous system agents.<br>References Wei, Z.L., et al.: PCT Int. Appl. 199pp. Patent 2009 CODEN:PIXXD2;<br></p>

<p>Applications N-(3,4-dimethylphenyl)acetamide (cas# 2198-54-1) is a useful research chemical.<br></p>

<p>Applications 5-Ethyl-2-fluorophenylboronic acid<br></p>

<p>Applications 1,6-Anhydro-β-L-gulopyranose is an intermediate used in the synthesis of Troxacitabine (T805580), which is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.<br>References Robak, T., et al.: Curr. Med. Chem., 18, 638 (2011); Kornblau, S.M., et al.: Clin. Cancer. Res., 16, 3721 (2010);<br></p>

<p>Applications 2,3-Dimethylbenzoquinone is a reagent in the preparation of hydroxycinnolines which has antifungal activity.<br>References Ryu, C., et al.: Bioorg. Med. Chem. Lett., 16, 1850 (2006)<br></p>

<p>Applications 4-Hydroxyphenylacetone (cas# 770-39-8) is a useful research chemical.<br></p>

<p>Applications trans-2-(Chloromethyl)cyclohexanemethanol is an impurity of Lurasidone Hydrochloride (L474920), an antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008)<br></p>

<p>Applications 3,4-Bis(isobutoxycarbonyl)benzoic Acid is a useful reagent in organic synthesis.<br></p>

<p>Applications Used in the preparation of homobifunctional rhodamine for labeling proteins.<br>References Corrie, J. et al.; Bioconjugate Chem. 9, 160 (1998)<br></p>

<p>Applications 3,5-Dimethoxytoluene (cas# 4179-19-5) is a useful research chemical.<br></p>

<p>Applications 2-Phenylcyclobutan-1-one (cas# 42436-86-2) is a useful research chemical.<br></p>

<p>Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.<br>References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),<br></p>

<p>Applications Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid (V850000); a lichen metabolite with anti-inflammatory properties.<br>References Shachak, M., et al.: Science, 236, 1098 (1987); Froberg, L., et al.: Lichenologist, 25, 83 (1993); Hesbacher, S., et al.: J. Chem. Ecology, 21, 233 (1995)<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester<br></p>

<p>Applications 4-(3-Oxetanyl)benzenemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.<br></p>

<p>Applications Ethyl 2,2-Dimethyl-3-(4-mercaptophenyl)propionate (cas# 869853-73-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Cyclohexylbutanoic Acid (cas# 4361-38-0) is a useful reagent for the preparation of oxoheterocyclylalkyl hydroxypiperidinylketones as USP19 inhibitors for treating diseases.<br>References Hewitt, P., et al.: PCT Int. Appl. (2018), WO 2018020242 A1<br></p>

<p>Applications 1,4-Dicyanobenzene is used in the preparation of aryl nitriles.<br>References Lee, H.G., et. al.: J. Am. Chem. Soc., 137, 648 (2015)<br></p>

<p>Applications Alkylating agent.<br></p>

<p>Impurity Darifenacin 5 Carboxymethyl Impurity/ Darifenacin Bromo Impurity<br>Applications 5-(2-Bromoethyl)-2,3-dihydrobenzofuran (cas# 127264-14-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 2-(p-Tolyl)benzoate is an intermediate in the synthesis of Telmisartan (T017000) analogs.<br>References Ries, U., et al.: J. Med. Chem., 36, 4040 (1993), Balmforth, A., et al.: Biol. Chem., 272, 4245 (1997),<br></p>

<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>

<p>Applications 5-Hydroxytoluene-2,4-disulfonic Acid acts as a synthetic reagent in the sulfonation of 2 and 3-Methylphenol.<br>References Strandlund, G., et al.: Acta Chem. Scand., 33, 261 (1979)<br></p>

<p>Applications Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate is used in synthesis of 1-Alkynyl(triphenyl)arsonium Tetrafluoroborates by onium transfer reaction of 1-Alkynyl(phenyl)iodonium Tetrafluoroborates with Triphenylarsine. Also, used in preparation of Furan- and Thiophene-substituted alkynes and alkynyl ketones by Copper Iodide-catalyzed coupling and carbonylation of Heterocyclic Boronic Acids with Alkynyliodonium salts.<br>References Nagaoka, T., et al.: Tetrah. Lett., 36, 261-4 (1995); Yu, Chan-Mo, et al.: Synlett, 2631-2634 (2005);<br></p>

<p>Applications N-Phenylanthranilic acid is used in biological studies for inhibitors of aldo-keto reductase 1C3 based on N-phenyl-aminobenzoates.<br>References Adeniji, A. O., et al.: J. Med. Chem., 55, 2311 (2012);<br></p>

<p>Stability Smelly, Volatile product<br>Applications 1,4-Cyclohexadiene Monoepoxide is a synthetic intermediate. It is used as a reactant in the enantioselective formal synthesis of 4-demethoxydaunomycin. Also used in the asymmetric synthesis of β-amino and vicinal amino alcohols.<br>References Sekine, A., et al.: Tetrahedron, 58, 75 (2002); Carree, F., et al.: Org. Lett., 7, 1023 (2005); Arai, K., et al.: J. Am. Chem. Soc., 129, 8103 (2007);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4,4'-Bis(isocyanatophenyl)oxide is a reagent used in the synthesis of lipid-conjugated Smac analogs with antitumor activity against human breast cancer cell lines.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Micewicz, E et al.: Bioorg. Med. Chem. Lett., 25, 4419 (2015);<br></p>

<p>Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications 5-Methylbenzotriazole intermediate.<br>References Vitale, G., et al.: Med. Chem., 5, 507 (2009), El-Sharief, A., et al.: Eur. J. Med. Chem., 44, 4315 (2009), Potter, A., et al.: Bioorg. Med. Chem. Lett., 20, 586 (2010),<br></p>

<p>Applications Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Romanov, G.V. et al.: Khim.-Farm. Zhur., 24, 28 (1990);<br></p>

<p>Applications Methyl 4-amino-2,3,5,6-tetrafluorobenzoate (cas# 715-37-7) is a useful research chemical.<br></p>